602 research outputs found
Lutzomyia longipalpis s.l. in Brazil and the impact of the Sao Francisco River in the speciation of this sand fly vector
Lutzomyia longipalpis s.l. (Diptera: Psychodidae) is the principal vector of Leishmania infantum chagasi in the Americas, and constitutes a complex of species. Various studies have suggested an incipient speciation process based on behavioral isolation driven by the chemotype of male sexual pheromones. It is well known that natural barriers, such as mountains and rivers can directly influence population divergence in several organisms, including insects. In this work we investigated the potential role played by the Sao Francisco River in eastern Brazil in defining the current distribution of Lu. longipalpis s.l. Our studies were based on analyses of polymorphisms of the cytochrome b gene (cyt b) sequences from Lu. longipalpis s.l. available in public databases, and from additional field-caught individuals. Altogether, 9 distinct populations and 89 haplotypes were represented in the analyses. Lu. longipalpis s.l. populations were grouped according to their distribution in regards to the 10°S parallel: north of 10°S (<10°S); and south of 10°S (>10°S). Our results suggest that although no polymorphisms were fixed, moderate genetic divergences were observed between the groups analyzed (i.e., FST = 0.184; and Nm = 2.22), and were mostly driven by genetic drift. The population divergence time estimated between the sand fly groups was about 0.45 million years (MY), coinciding with the time of the change in the course of the Sao Francisco River, during the Mindel glaciation. Overall, the polymorphisms on the cyt b haplotypes and the current speciation process detected in Lu. longipalpis s.l. with regards to the distribution of male sexual pheromones suggest a role of the Sao Francisco River as a significant geographical barrier in this process
Identificação molecular de cochonilhas-farinhentas (Pseudococcidae) associadas à videira no Submédio São Francisco.
Este trabalho teve como objetivo a identificação de cochonilhas-farinhentas por meio de análise molecular
Maconellicoccus hirsutus (Green, 1908) (Hemiptera: Pseudococcidae): exotic pest introduced on vine in the São Francisco Valley.
The pink hibiscus mealybug, Maconellicoccus hirsutusis a polyphagous pest that attacks more than 200 generous and about more than 74 botanical families of cultivated or uncultivated plants. Many of these plants are of economic importance to Brazil, including cotton, cocoa, coffee, coconut, citrus, cucumber, corn, beans, papaya, sweet potatoes, figs, grapes, guavas, peanuts, roses, hibiscusand ornamental palms. However, M. hirsutus was recently introduced in Brazil. This study reported the first time occurence this pest in São Francisco Valley, Northeastern Brazil. After the pest presence alert, samplings were taken inside and around of the plantation of vines. The mealybugs were found attacking all structures of grape plants (Vitis vinifera), native plants of caatinga, weeds, "windbreaks" and fruit trees. In grape plants, the mealybugs inside bunches caused the reduction of the fruits quality and the discard of them, and on the sprouts they cause the inhibition of branches development, compromising at least two harvests. Thus, by severity of the damage, M. hirsutus may be considered one of the most important pests of the grape culture in theregion. The control of this new pest is a big challenge that will require a set of actions including chemical insecticides registration, the development of an effective monitoring plan as well as the search and use of natural enemies adapted to the region
Phlebotomus papatasi SP15: mRNA expression variability and amino acid sequence polymorphisms of field populations
Citation: Ramalho-Ortigao, M., Coutinho-Abreu, I. V., Balbino, V. Q., Figueiredo, C. A. S., Mukbel, R., Dayem, H., . . . McDowell, M. A. (2015). Phlebotomus papatasi SP15: mRNA expression variability and amino acid sequence polymorphisms of field populations. Parasites & Vectors, 8, 14. doi:10.1186/s13071-015-0914-2Background: The Phlebotomus papatasi salivary protein PpSP15 was shown to protect mice against Leishmania major, suggesting that incorporation of salivary molecules in multi-component vaccines may be a viable strategy for anti-Leishmania vaccines. Methods: Here, we investigated PpSP15 predicted amino acid sequence variability and mRNA profile of P. papatasi field populations from the Middle East. In addition, predicted MHC class II T-cell epitopes were obtained and compared to areas of amino acid sequence variability within the secreted protein. Results: The analysis of PpSP15 expression from field populations revealed significant intra-and interpopulation variation.. In spite of the variability detected for P. papatasi populations, common epitopes for MHC class II binding are still present and may potentially be used to boost the response against Le. major infections. Conclusions: Conserved epitopes of PpSP15 could potentially be used in the development of a salivary gland antigen-based vaccine.Additional Authors: Lobo, N. F.;Mahon, A. R.;Emrich, S. J.;Kamhawi, S.;Collins, F. H.;McDowell, M. A
Consumo de um simbiótico no controle urêmico de portadores de doença renal crônica em hemodiálise.
Suplemento. Edição dos resumos do 13º Congresso Nacional da Sociedade Brasileira de Alimentação e Nutrição, São Paulo, 2015
Characterizing the initial conditions of heavy-ion collisions at the LHC with mean transverse momentum and anisotropic flow correlations
Correlations between mean transverse momentum and anisotropic flow coefficients or are measured as a function of centrality in Pb–Pb and Xe–Xe collisions at sqrt(sNN) = 5.02 TeV and 5.44 TeV, respectively, with ALICE. In addition, the recently proposed higher-order correlation between [pt], v2, and v3 is measured for the first time, which shows an anticorrelation for the presented centrality ranges. These measurements are compared with hydrodynamic calculations using IP-Glasma and TRENTO initial-state shapes, the former based on the Color Glass Condensate effective theory with gluon saturation, and the latter a parameterized model with nucleons as the relevant degrees of freedom. The data are better described by the IP-Glasma rather than the TRENTO based calculations. In particular, Trajectum and JETSCAPE predictions, both based on the TRENTO initial state model but with different parameter settings, fail to describe the measurements. As the correlations between [pt] and vn are mainly driven by the correlations of the size and the shape of the system in the initial state, these new studies pave a novel way to characterize the initial state and help pin down the uncertainty of the extracted properties of the quark–gluon plasma recreated in relativistic heavy-ion collisions
Search for a common baryon source in high-multiplicity pp collisions at the LHC
We report on the measurement of the size of the particle-emitting source from two-baryon correlations with ALICE in high-multiplicity pp collisions at s=13 TeV. The source radius is studied with low relative momentum p–p, p‾–p‾, p–Λ, and p‾–Λ‾ pairs as a function of the pair transverse mass mT considering for the first time in a quantitative way the effect of strong resonance decays. After correcting for this effect, the radii extracted for pairs of different particle species agree. This indicates that protons, antiprotons, Λ s, and Λ‾ s originate from the same source. Within the measured mT range (1.1–2.2) GeV/c2the invariant radius of this common source varies between 1.3 and 0.85 fm. These results provide a precise reference for studies of the strong hadron–hadron interactions and for the investigation of collective properties in small colliding systems. © 2020 CERN for the benefit of the ALICE CollaborationPeer reviewe
Measurement of the Lifetime and Λ Separation Energy of _{Λ}^{3}H
The most precise measurements to date of the _{Λ}^{3}H lifetime τ and Λ separation energy B_{Λ} are obtained using the data sample of Pb-Pb collisions at sqrt[s_{NN}]=5.02 TeV collected by ALICE at the LHC. The _{Λ}^{3}H is reconstructed via its charged two-body mesonic decay channel (_{Λ}^{3}H→^{3}He+π^{-} and the charge-conjugate process). The measured values τ=[253±11(stat)±6(syst)] ps and B_{Λ}=[102±63(stat)±67(syst)] keV are compatible with predictions from effective field theories and confirm that the _{Λ}^{3}H structure is consistent with a weakly bound system
General balance functions of identified charged hadron pairs of (pi,K,p) in Pb-Pb collisions at 2.76 TeV
First measurements of balance functions (BFs) of all combinations of identified charged hadron ( π , K, p)
pairs in Pb–Pb collisions at √sNN = 2.76 TeV recorded by the ALICE detector are presented. The BF
measurements are carried out as two-dimensional differential correlators versus the relative rapidity
(delta-y) and azimuthal angle (delta-φ) of hadron pairs, and studied as a function of collision centrality. The delta-φ
dependence of BFs is expected to be sensitive to the light quark diffusivity in the quark–gluon plasma.
While the BF azimuthal widths of all pairs substantially decrease from peripheral to central collisions, the
longitudinal widths exhibit mixed behaviors: BFs of π π and cross-species pairs narrow significantly in
more central collisions, whereas those of KK and pp are found to be independent of collision centrality.
This dichotomy is qualitatively consistent with the presence of strong radial flow effects and the existence
of two stages of quark production in relativistic heavy-ion collisions. Finally, the first measurements of
the collision centrality evolution of BF integrals are presented, with the observation that charge balancing
fractions are nearly independent of collision centrality in Pb–Pb collisions. Overall, the results presented
provide new and challenging constraints for theoretical models of hadron production and transport in
relativistic heavy-ion collisions
Measurement of the non-prompt D-meson fraction as a function of multiplicity in proton-proton collisions at = 13 TeV
The fractions of non-prompt (i.e. originating from beauty-hadron decays) D0
and D+ mesons with respect to the inclusive yield are measured as a function of the
charged-particle multiplicity in proton-proton collisions at a centre-of-mass energy of √s =
13 TeV with the ALICE detector at the LHC. The results are reported in intervals of
transverse momentum (pT) and integrated in the range 1 < pT < 24 GeV/c. The fraction
of non-prompt D0 and D+ mesons is found to increase slightly as a function of pT in
all the measured multiplicity intervals, while no significant dependence on the charged-
particle multiplicity is observed. In order to investigate the production and hadronisation
mechanisms of charm and beauty quarks, the results are compared to PYTHIA 8 as well
as EPOS 3 and EPOS 4 Monte Carlo simulations, and to calculations based on the colour
glass condensate including three-pomeron fusion
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