Clinical Placement: Experiences, School and Hospital-based Gaps and Challenges of Undergraduate Nursing Students of the University of Cape Coast

The goal of the study was to assess the school-based and hospital-based gaps and challenges among undergraduate nursing students. The specific objectives of the study was identify the gaps between school-based and hospital-based learning, explore students’ clinical practice experiences and to determine the challenges students encounter during clinical placement. The Explanatory Mixed Method Design was used for the study. For the quantitative part, the simple random sampling technique was used to select 141 study participants. Questionnaires were used to collect numeric data. Quantitative data was analysed using IBM SPSS version 21. For the qualitative part, purposive sampling was used to select five participants for interviewing. Braun and Clarke (2006) steps for thematic analysis was employed to analyse the responses for the interviewing. The qualitative data was used to validate the quantitative results.The findings from the quantitative and qualitative aspects of the study point to common gaps and challenges and experiences of nursing students. The findings showed a consensus on differences in types of equipment and availability of equipment, learning experiences and clinical nursing practices between the hospital and school settings. Challenges with students attending more errands, poor supervision and combining school and academic work were also highlighted in the two data sets. However, the two data sets suggest that nurses create an enabling environment for the students to meet their learning objectives. This study has highlighted areas that require improvement and further research. Gaps and challenges with school learning and clinical placement in terms of making students aware of their objectives, availability of equipment, ensuring proper supervision and feedback need to be addressed. Keywords: Undergraduate nursing, clinical placement, hospital learning, theory-practice DOI: 10.7176/JEP/11-5-04 Publication date: February 29th 202

Hemodialysis Removes Uremic Toxins That Alter the Biological Actions of Endothelial Cells

Chronic kidney disease is linked to systemic inflammation and to an increased risk of ischemic heart disease and atherosclerosis. Endothelial dysfunction associates with hypertension and vascular disease in the presence of chronic kidney disease but the mechanisms that regulate the activation of the endothelium at the early stages of the disease, before systemic inflammation is established remain obscure. In the present study we investigated the effect of serum derived from patients with chronic kidney disease either before or after hemodialysis on the activation of human endothelial cells in vitro, as an attempt to define the overall effect of uremic toxins at the early stages of endothelial dysfunction. Our results argue that uremic toxins alter the biological actions of endothelial cells and the remodelling of the extracellular matrix before signs of systemic inflammatory responses are observed. This study further elucidates the early events of endothelial dysfunction during toxic uremia conditions allowing more complete understanding of the molecular events as well as their sequence during progressive renal failure

Optimizing Blood Transfusion Service Delivery across the West Africa Sub-Region

The sub-continent of West Africa is made up of 16 countries: Benin, Burkina Faso, Cape Verde, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Liberia, Mali, Mauritania, Niger, Nigeria, Senegal, Sierra Leone, The Gambia and Togo. As of 2018, the population of the sub-continent was estimated at about 381 million. The main challenge associated with blood transfusion service delivery across the sub-region concerns adequacy and safety. In this chapter, we highlighted the challenges associated with the delivery of a quality blood transfusion service in countries in the sub-region including: implementation of component therapy rather than whole blood transfusion, effective cold chain management of blood and blood products, alloimmunization prevention, implementation of column agglutination and automation rather than the convention manual tube method in blood transfusion testing, effective management of major haemorrhage, optimization of screening for transfusion transmissible infections, optimizing blood donation, implementation of universal leucodepletion of blood and blood products, effective management of transfusion-dependent patients, pre-operative planning and management of surgical patients, management of Rhesus D negative pregnancy and women with clinically significant alloantibodies, implementation of haemovigilance system, implementation of alternatives to allogenic blood, availability and use of specialized blood products, optimizing safe blood donation, enhancing blood transfusion safety, operating a quality management system-based blood transfusion service and implementation of non-invasive cell-free foetal DNA testing. There is the urgent need for the implementation of evidence-based best practices in blood transfusion service delivery across the sub-region to allow for excellent, safe, adequate and timely blood transfusion service delivery across the sub-region

Educational readiness among health professionals in rheumatology: Low awareness of EULAR offerings and unfamiliarity with the course content as major barriers—results of a EULAR-funded European survey

Background Ongoing education of health professionals in rheumatology (HPR) is critical for high-quality care. An essential factor is education readiness and a high quality of educational offerings. We explored which factors contributed to education readiness and investigated currently offered postgraduate education, including the European Alliance of Associations for Rheumatology (EULAR) offerings.Methods and participants We developed an online questionnaire, translated it into 24 languages and distributed it in 30 European countries. We used natural language processing and the Latent Dirichlet Allocation to analyse the qualitative experiences of the participants as well as descriptive statistics and multiple logistic regression to determine factors influencing postgraduate educational readiness. Reporting followed the Checklist for Reporting Results of Internet E-Surveys guideline.Results The questionnaire was accessed 3589 times, and 667 complete responses from 34 European countries were recorded. The highest educational needs were ‘professional development’, ‘prevention and lifestyle intervention’. Older age, more working experience in rheumatology and higher education levels were positively associated with higher postgraduate educational readiness. While more than half of the HPR were familiar with EULAR as an association and the respondents reported an increased interest in the content of the educational offerings, the courses and the annual congress were poorly attended due to a lack of awareness, comparatively high costs and language barriers.Conclusions To promote the uptake of EULAR educational offerings, attention is needed to increase awareness among national organisations, offer accessible participation costs, and address language barriers

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Virginia Avis Ulrey standing in concert gown

Virginia Avis Ulrey-Purdue Music Organization concert choir gown, 1942-152 Sheetz St. West Lafayette. Photographer-Theodora Ulrey Andrews; gift of Michael Humnicky, 2007

Oral history interview with Teddy Andrews, 2007 Aug. 10

Theodora Andrews was born in this area and graduated from West Lafayette High School in 1939. She recounts early staff members in the Library Eleanor Commack, Margaret Sullivan and Esther Schlunt. The Director was John Moriarty who replaced Professor Hepburn. Also a description of the early Departmental Libraries. Pharmacy, Chemistry and Library in The Agriculture Experiment Station. Purdue being the land grant institution. Andrews talks about early days as the Librarian in the General Library and then her long tenure as the School of Pharmacy and Pharmacal Sciences Librarian, after receiving her degree in Library Science. Andrews was an active member of the Special Libraries Association at the state and national level as well as the medical library association