Autonomia-Relacionada como Tendência do Desenvolvimento do Self: Novas Evidências em um Contexto Brasileiro

Studies in Brazil on developmental trajectories of the self , mostly with mothers of young children, indicate a prevalence of the related autonomy model (RA). Aiming to broaden the investigation of this trend, two studies were realized: (a) with grandparents, mothers, fathers and their sons and daughters (16-25 years old), and (b) with four groups of caretakersof children up to one year old, with diverse educational levels, non-randomly selected. We observed predominance of RA self for all participants. The effect of school level over autonomy was confirmed for fathers, RA of fathers and sons and daughters (study 1), and of mothers (study 2). Mothers who were raised in Rio de Janeiro (state capital) had higher autonomy scores. The results support the family consistency of the related-autonomy model of development of the self.Estudos brasileiros, em sua maioria com mães de crianças pequenas, sobre as trajetórias de desenvolvimento do self, indicam predominância do modelo de autonomia-relacionada (AR). Visando ampliar a investigação dessa tendência, foram realizados dois estudos: 1) com avós (ôs), mães, pais e filhos (16-25 anos) e 2) quatro grupos de cuidadoras de crianças com até um ano, com níveis de escolaridade diversos, selecionados não aleatoriamente. Observamos predomínio de características de self AR para todos os participantes. O efeito da escolaridade sobre autonomia foi confirmado para os pais, a AR de pais e filhos (estudo 1), e de mães (estudo 2). Mães criadas no Rio de Janeiro (capital) têm maiores escores de autonomia. A consistência familiar de modelo de self autônomo-relacionado foi evidenciada

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

O uso do solo urbano: históricas desigualdades, novas leis e algumas percepções de moradores da favela da Rocinha

Este trabalho aborda a interpelação exercida pelo espaço urbano nos processos de subjetivação do homem contemporâneo, com especial atenção a situações relacionadas ao direito e ao uso do solo. É realizado um breve histórico do conceito de “uso social do solo” no país, de políticas públicas que vêm sendo implantadas com vistas à produção de habitação popular e à regularização fundiária de favelas e apresentadas impressões de moradores da favela da Rocinha, localizada na cidade do Rio de Janeiro, em face deste processo, ora em andamento em algumas de suas áreas. Os relatos dos moradores foram obtidos a partir dos trabalhos de campo realizados no âmbito da pesquisa “Espaço Urbano Contemporâneo e Subjetividade: um foco especial sobre as favelas do Rio de Janeiro”, sediada no Programa de Pós-Graduação em Psicologia Social, da UERJ, com apoio financeiro Prodoc/CAPES

Concepções sobre autonomia em faixas etárias diversas

Resumo Autonomia e relação são tendências universais desenvolvidas ao longo da ontogênese, concomitantes com distintas fases psicossociais. A autonomia é compreendida como uma necessidade psicológica que não exclui a de relação com os outros e proximidade interpessoal. Assim, o objetivo deste estudo foi analisar as crenças e concepções sobre autonomia em diferentes faixas etárias. Participaram 110 sujeitos, dentre eles crianças de 10 a 13 anos de idade; adolescentes entre 15 e 18 anos; jovens e adultos entre 20 e 50 anos; e adultos acima dos 50. Os participantes responderam um questionário de dados sociodemográficos e à questão de evocação de palavras ou expressões relacionadas a autonomia. Utilizando a análise de conteúdo temático-categorial, foram estabelecidas dez categorias, e as respostas foram classificadas de acordo com elas. Diferenças entre as faixas etárias foram encontradas, sendo que as categorias independência e senso de liberdade foram as mais frequentes. Os resultados sugerem o desenvolvimento de um processo contínuo com a construção da identidade se dando ao longo do ciclo vital

Intranasal Liposomal Formulation of Spike Protein Adjuvanted with CpG Protects and Boosts Heterologous Immunity of hACE2 Transgenic Mice to SARS-CoV-2 Infection

Mucosal vaccination appears to be suitable to protect against SARS-CoV-2 infection. In this study, we tested an intranasal mucosal vaccine candidate for COVID-19 that consisted of a cationic liposome containing a trimeric SARS-CoV-2 spike protein and CpG-ODNs, a Toll-like receptor 9 agonist, as an adjuvant. In vitro and in vivo experiments indicated the absence of toxicity following the intranasal administration of this vaccine formulation. First, we found that subcutaneous or intranasal vaccination protected hACE-2 transgenic mice from infection with the wild-type (Wuhan) SARS-CoV-2 strain, as shown by weight loss and mortality indicators. However, when compared with subcutaneous administration, the intranasal route was more effective in the pulmonary clearance of the virus and induced higher neutralizing antibodies and anti-S IgA titers. In addition, the intranasal vaccination afforded protection against gamma, delta, and omicron virus variants of concern. Furthermore, the intranasal vaccine formulation was superior to intramuscular vaccination with a recombinant, replication-deficient chimpanzee adenovirus vector encoding the SARS-CoV-2 spike glycoprotein (Oxford/AstraZeneca) in terms of virus lung clearance and production of neutralizing antibodies in serum and bronchial alveolar lavage (BAL). Finally, the intranasal liposomal formulation boosted heterologous immunity induced by previous intramuscular vaccination with the Oxford/AstraZeneca vaccine, which was more robust than homologous immunity

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved