5 research outputs found
Feasibility study of biofuel production from freshwater fern, Azolla sp in Anzali Wetland
- Author
- Publication venue
- Publication date
- 01/01/2013
- Field of study
Production of bioethanol through acidic and enzymatic hydrolysis of aquatic Azolla sp., as a new source of bio-mass, has been performed, as a means to control increasing growth and reducing undesirable effects of this plant in Anzali lagoon.
After sampling, drying and crushing, Azolla was hydrolyzed, using diluted acid and enzyme. Diluted acid hydrolysis was done using both autoclave and a high-pressure system (Batch Synth® Microwave synthesizer). The effects of temperature and time (in autoclave) and concentration of acid (in both) were compared. Cellubrix®, a ommercial cellulase source, was used for enzymatic hydrolysis process. The amounts of reducing sugars, glucose and furfural, released from hydrolyzate, were measured. To produce alcohol, Sacchromyces cerevisiae (to ferment sixcarbon sugars), Zygowilliopsis californica and Pichia stipitis (to ferment five-carbon and sixcarbon sugars) were used.
Maximum amounts of glucose (4.83% w/w) and reducing sugars (14.15% w/w) were obtained using acid hydrolysis in autoclave. In the microwave oven, maximum glucose (5.04% w/w) and reducing sugars (13.27 w/w) were obtained at 180 and 200 °C, respectively. Under these conditions, maximum produced furfural was 1.54 g/L. The difference between amounts of furfural obtained from acid hydrolysis of Azolla in microwave oven compared to autoclave was statistically significant. Amounts of alcohol produced and its yields were 3.99 g/L and 33.13% for S. cerevisiae in 48 hours, 3.73 g/L and 30.45% for Pichia stipites in 48 hours, and 3.73 g/L and 30.45% for Z. californica in 24 hours after inoculation, respectively, with significant differences.
Statistical comparison of results showed significant differences (P<0.05) in glucose production, at different conditions. Amounts of reducing sugars and glucose increased after optimization of levels of acid, time, and temperature. The overall optimum released sugar and glucose were obtained with 1.67% (w/v) acid using autoclave. Higher temperatures in microwave oven caused a significant increase (P<0.05) in furfural. Furfural severely inhibits fermentation. Hence, regarding the issues of energy consumption and time, amounts of inhibiting substances and sugar production, autoclave is found to be superior to the high temperature and pressure, generated in
microwave oven, for hydrolyzing Azolla. Furthermore, given the amounts of Azolla in Anzali lagoon, it may be recommendable to use this plant as a biomass resource
Role of Chloroquine and Cocaine Injection on Synaptophysin Protein Level in PTSD Model of Male Wistar Rat
- Publication venue
- Publisher: School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences
- Publication date
- 06/04/2020
- Field of study
Introduction: Drug abuse could induce molecular changes in synapses, leading to mood-related disorders. In addition, some patients suffering from mood disease use drug to get comfort. In some behavioral disorders, autophagy inhibitor drugs are used.Materials and Methods: In the current study, the effect of chloroquine (CQ, an autophagy inhibitor drug) in a rat model of Post-Traumatic Stress Disorder (PTSD), together with the role of cocaine abuse was examined. Rats were injected with the CQ and/or cocaine alone or following single-prolonged-stress exposure and were confirmed as PTSD, using elevated-plus maze (EPM) test and then protein level of synaptophysin (a synaptic vesicle glycoprotein) was investigated by western blotting tecnique. It should be noted that cocaine was administered intracerebroventricularly (i.c.v, 20µg/rat) and CQ was administered intraperitoneally (50 mg/kg, IP).Results: Obtained data revealed that PTSD and chronic administration of cocaine (i.c.v) in PTSD animals could increase the level of Synaphtophysin. CQ injection in them decreased Synaptophysin. So cocaine increase Synaphtophysin while CQ decrease it in PTSD animals.Conclusion: The current data suggests altering neural plasticity by Synaptophysin protein level changes in brain on PTSD rats
Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
- Abbastabar Hedayat
- Abd El Razek Hassan Magdy
- Abd El Razek Muhammed Magdy
- Abd-Allah Foad
- Abdelalim Ahmed
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abdullah Kanaan Hamagharib
- Abedi Aidin
- Abedi Parisa
- Abegaz Kedir Hussein
- Abolhassani Hassan
- Abosetugn Akine Eshete
- Aboyans Victor
- Abrams Elissa M.
- Abreu Lucas Guimaraes
- Abrigo Michael R. M.
- Abu Haimed Abdulaziz Khalid
- Abu-Gharbieh Eman
- Abu-Raddad Laith Jamal
- Abualhasan Ahmed
- Abushouk Abdelrahman I.
- Acebedo Alyssa
- Ackerman Ilana N.
- Adabi Maryam
- Adair Tim
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adelson Jaimie D.
- Adeoye Abiodun Moshood
- Adetokunboh Olatunji O.
- Adham Davoud
- Advani Shailesh M.
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agardh Emilie E.
- Agarwal Gina
- Agasthi Pradyumna
- Agesa Kareha M.
- Aghaali Mohammad
- Aghamir Seyed Mohammad Kazem
- Agrawal Anurag
- Ahmad Tauseef
- Ahmadi Alireza
- Ahmadi Keivan
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmadpour Ehsan
- Ahmed Muktar Beshir
- Aji Budi
- Akalu Temesgen Yihunie
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akombi Blessing
- Akunna Chisom Joyqueenet
- Al-Aly Ziyad
- Al-Mekhlafi Hesham M.
- Al-Raddadi Rajaa M.
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Samiah
- Alam Tahiya
- Alanezi Fahad Mashhour
- Alanzi Turki M.
- Albertson Samuel B.
- Alcalde-Rabanal Jacqueline Elizabeth
- Alema Niguse Meles
- Alemu Biresaw Wassihun
- Alemu Yihun Mulugeta
- Alhabib Khalid F.
- Alhassan Robert Kaba
- Ali Muhammad
- Ali Saqib
- Alicandro Gianfranco
- Alijanzadeh Mehran
- Alinia Cyrus
- Alipour Vahid
- Alizade Hesam
- Aljunid Syed Mohamed
- Alla Francois
- Allebeck Peter
- Almadi Majid Abdulrahman Hamad
- Almasi Ali
- Almasi-Hashiani Amir
- Almasri Nihad A.
- Almulhim Abdulaziz M.
- Alonso Jordi
- Altirkawi Khalid A.
- Alumran Arwa Khalid
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J.
- Amare Azmeraw T.
- Amare Bekalu
- Amini Saeed
- Amini-Rarani Mostafa
- Aminorroaya Arya
- Amiri Fatemeh
- Amit Arianna Maever L.
- Amugsi Dickson A.
- Amul Gianna Gayle Herrera
- Anbesu Etsay Woldu
- Ancuceanu Robert
- Anderlini Deanna
- Anderson Jason A.
- Andrei Catalina Liliana
- Andrei Tudorel
- Androudi Sofia
- Angus Colin
- Anjomshoa Mina
- Ansari Fereshteh
- Ansari Iman
- Ansari-Moghaddam Alireza
- Antonazzo Ippazio Cosimo
- Antonio Carl Abelardo T.
- Antony Catherine M.
- Antriyandarti Ernoiz
- Anvari Davood
- Anwer Razique
- Appiah Seth Christopher Yaw
- Arab-Zozani Morteza
- Arabloo Jalal
- Aravkin Aleksandr Y.
- Arba Aseb Arba Kinfe
- Aremu Olatunde
- Ariani Filippo
- Aripov Timur
- Armoon Bahram
- Arnlov Johan
- Arowosegbe Oluwaseyi Olalekan
- Aryal Krishna K.
- Arzani Afsaneh
- Asaad Malke
- Asadi-Aliabadi Mehran
- Asadi-Pooya Ali A.
- Asgari Samaneh
- Asghari Babak
- Ashbaugh Charlie
- Assmus Michael
- Atafar Zahra
- Athari Seyyed Shamsadin
- Atnafu Desta Debalkie
- Atout Maha Moh'd Wahbi
- Atre Sachin R.
- Atteraya Madhu Sudhan
- Ausloos Floriane
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel Gbenato Arthur
- Ayano Getinet
- Ayanore Martin Amogre
- Aynalem Getie Lake
- Aynalem Yared Asmare
- Ayza Muluken Altaye
- Azari Samad
- Azarian Ghasem
- Azene Zelalem Nigussie
- Azhar Gulrez
- Azzopardi Peter S.
- Babaee Ebrahim
- Badawi Alaa
- Badiye Ashish D.
- Bagherzadeh Mojtaba
- Bagli Eleni
- Bahrami Mohammad Amin
- Baig Atif Amin
- Bairwa Mohan
- Bakhshaei Mohammad Hossein
- Bakhtiari Ahad
- Bakkannavar Shankar M.
- Balachandran Arun
- Balakrishnan Senthilkumar
- Balalla Shivanthi
- Balassyano Shelly
- Baldasseroni Alberto
- Bali Ahmed Omar
- Ball Kylie
- Ballew Shoshana H.
- Balzi Daniela
- Banach Maciej
- Bandpei Mohammad A. Mohseni
- Banerjee Srikanta K.
- Banik Palash Chandra
- Bannick Marlena S.
- Bante Agegnehu Bante
- Bante Simachew Animen
- Baraki Adhanom Gebreegziabher
- Barboza Miguel A.
- Barker-Collo Suzanne Lyn
- Barnighausen Till Winfried
- Barrero Lope H.
- Barthelemy Celine M.
- Barua Lingkan
- Barzegar Akbar
- Basaleem Huda
- Bassat Quique
- Basu Sanjay
- Baune Bernhard T.
- Bayati Mohsen
- Baye Bayisa Abdissa
- Bazmandegan Gholamreza
- Becker Jacob S.
- Bedi Neeraj
- Beghi Ettore
- Behzadifar Masoud
- Bejot Yannick
- Bekuma Tariku Tesfaye Tesfaye
- Bell Michelle L.
- Bello Aminu K.
- Bender Rose G.
- Bennett Derrick A.
- Bennitt Fiona B.
- Bensenor Isabela M.
- Benziger Catherine P.
- Berhe Kidanemaryam
- Berman Adam E.
- Bernabe Eduardo
- Bernstein Robert S.
- Bertolacci Gregory J.
- Bhagavathula Akshaya Srikanth
- Bhageerathy Reshmi
- Bhala Neeraj
- Bhandari Dinesh
- Bhardwaj Pankaj
- Bhat Anusha Ganapati
- Bhattacharyya Krittika
- Bhattarai Suraj
- Bhutta Zulfiqar A.
- Bibi Sadia
- Bicer Burcu Kucuk
- Biehl Molly H.
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bin Sayeed Muhammad Shahdaat
- Bin Zaman Sojib
- Biondi Antonio
- Birihane Binyam Minuye
- Bisanzio Donal
- Bisignano Catherine
- Biswas Raaj Kishore
- Bitew Helen
- Bjorge Tone
- Bockarie Moses John
- Bohlouli Somayeh
- Bohluli Mehdi
- Bojia Hunduma Amensisa
- Bolla Srinivasa Rao
- Boloor Archith
- Boon-Dooley Alexandra S.
- Borges Guilherme
- Borzi Antonio Maria
- Borzouei Shiva
- Bose Dipan
- Bosetti Cristina
- Boston Sofia
- Boufous Soufiane
- Bourne Rupert
- Brady Oliver J.
- Braithwaite Dejana
- Brauer Michael
- Brayne Carol
- Breitborde Nicholas J. K.
- Breitner Susanne
- Brenner Hermann
- Breusov Alexey V.
- Briant Paul Svitil
- Briggs Andrew M.
- Briko Andrey Nikolaevich
- Briko Nikolay Ivanovich
- Britton Gabrielle B.
- Brugha Traolach
- Bryazka Dana
- Buchbinder Rachelle
- Bumgarner Blair R.
- Burkart Katrin
- Burnett Richard Thomas
- Busse Reinhard
- Butt Zahid A.
- Caetano dos Santos Florentino Luciano
- Cahill Leah E.
- Cahuana-Hurtado Lucero
- Cai Tianji
- Callender Charlton S. K. H.
- Camera Luis Alberto
- Campos-Nonato Ismael R.
- Cao Jackie
- Car Josip
- Car Lorainne Tudor
- Cardenas Rosario
- Carreras Giulia
- Carrero Juan J.
- Carvalho Felix
- Castaldelli-Maia Joao Mauricio
- Castaneda-Orjuela Carlos A.
- Castelpietra Giulio
- Castle Chris D.
- Castro Emma
- Castro Franz
- Catala-Lopez Ferran
- Causey Kate
- Cederroth Christopher R.
- Cercy Kelly M.
- Cerin Ester
- Chalek Julian
- Chandan Joht Singh
- Chang Alex R.
- Chang Angela Y.
- Chang Jung-Chen
- Chang Kai-Lan
- Charan Jaykaran
- Charlson Fiona J.
- Chattu Vijay Kumar
- Chaturvedi Sarika
- Cherbuin Nicolas
- Chimed-Ochir Odgerel
- Chin Ken Lee
- Chirinos-Caceres Jesus Lorenzo
- Cho Daniel Youngwhan
- Choi Jee-Young Jasmine
- Christensen Hanne
- Chu Dinh-Toi
- Chung Michael T.
- Chung Sheng-Chia
- Cicuttini Flavia M.
- Ciobanu Liliana G.
- Cirillo Massimo
- Cislaghi Beniamino
- Classen Thomas Khaled Dwayne
- Cohen Aaron J.
- Collins Emma L.
- Comfort Haley
- Compton Kelly
- Conti Sara
- Cooper Owen R.
- Corso Barbara
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Cousin Ewerton
- Cowden Richard G.
- Cowie Benjamin C.
- Cromwell Elizabeth A.
- Croneberger Andrew J.
- Cross Di H.
- Cross Marita
- Crowe Christopher Stephen
- Cruz Jessica A.
- Cummins Steven
- Cunningham Matthew
- D'Amico Emanuele
- da Silva Diana Dias
- Dahlawi Saad M. A.
- Dai Haijiang
- Dai Hancheng
- Damasceno Albertino Antonio Moura
- Damiani Giovanni
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Dangel William James
- Danielsson Anna-Karin
- Dargan Paul I.
- Darshan B. B.
- Darwesh Aso Mohammad
- Daryani Ahmad
- Das Gupta Rajat
- Das Neves Jose
- Das Jai K.
- Dash Aditya Prasad
- Davey Gail
- Davila-Cervantes Claudio Alberto
- Davis Adrian C.
- Davitoiu Dragos Virgil
- Davletov Kairat
- De Leo Diego
- De Neve Jan-Walter
- Dean Frances E.
- DeCleene Nicole K.
- Deen Amanda
- Defo Barthelemy Kuate
- Degenhardt Louisa
- DeLang Marissa
- Dellavalle Robert Paul
- Demeke Feleke Mekonnen
- Demoz Gebre Teklemariam
- Demsie Desalegn Getnet
- Denova-Gutierrez Edgar
- Dereje Nebiyu Dereje
- Deribe Kebede
- Dervenis Nikolaos
- Desai Rupak
- Desalew Assefa
- Dessie Getenet Ayalew
- Deuba Keshab
- Dharmaratne Samath Dhamminda
- Dhungana Govinda Prasad
- Dianatinasab Mostafa
- Diaz Daniel
- Dichgans Martin
- Didarloo Alireza
- Dingels Zachary V.
- Dippenaar Ilse N.
- Dirac M. Ashworth
- Djalalinia Shirin
- Do Hoa Thi
- Dokova Klara
- Doku David Teye
- Dolecek Christiane
- Dolgert Andrew J.
- Dorostkar Fariba
- Doshi Chirag P.
- Doshi Pratik P.
- Doshmangir Leila
- Douiri Abdel
- Doxey Matthew C.
- Doyle Kerrie E.
- Driscoll Tim Robert
- Dubljanin Eleonora
- Dunachie Susanna J.
- Duncan Bruce B.
- Duraes Andre Rodrigues
- Eagan Arielle Wilder
- Ebrahimi Hedyeh
- Edvardsson David
- Effiong Andem
- Ehrlich Joshua R.
- El Nahas Nevine
- El Sayed Iman
- El Tantawi Maha
- El-Jaafary Shaimaa I.
- Elbarazi Iffat
- Elgendy Islam Y.
- Elhabashy Hala Rashad
- Elsharkawy Aisha
- Elyazar Iqbal R. F.
- Emamian Mohammad Hassan
- Emmons-Bell Sophia
- Erskine Holly E.
- Eshrati Babak
- Eskandari Khalil
- Eskandarieh Sharareh
- Esmaeilnejad Saman
- Esmaeilzadeh Firooz
- Esteghamati Alireza
- Esteghamati Sadaf
- Estep Kara
- Etemadi Arash
- Etisso Atkilt Esaiyas
- Ezekannagha Oluchi
- Fanzo Jessica
- Farag Tamer
- Farahmand Mohammad
- Faraj Anwar
- Faraon Emerito Jose A.
- Fareed Mohammad
- Faridnia Roghiyeh
- Farinha Carla Sofia e Sa
- Farioli Andrea
- Faris Pawan Sirwan
- Faro Andre
- Faruque Mithila
- Farzadfar Farshad
- Fattahi Nazir
- Fazaeli Ali Akbar
- Fazlzadeh Mehdi
- Feigin Valery L.
- Feldman Rachel
- Fereshtehnejad Seyed-Mohammad
- Fernandes Eduarda
- Ferrara Giannina
- Ferrara Pietro
- Ferrari Alize J.
- Ferreira Manuela L.
- Feyissa Garumma Tolu
- Filip Irina
- Fischer Florian
- Fisher James L.
- Fitzgerald Ryan
- Flohr Carsten
- Flor Luisa Sorio
- Foigt Nataliya A.
- Folayan Morenike Oluwatoyin
- Fomenkov Artem Alekseevich
- Force Lisa M.
- Fornari Carla
- Forooshani Zahra Sadat Dibaji
- Foroutan Masoud
- Fox Jack T.
- Francis Joel Msafiri
- Frank Tahvi D.
- Franklin Richard Charles
- Freitas Marisa
- Fu Weijia
- Fukumoto Takeshi
- Fukutaki Kai
- Fuller John E.
- Fullman Nancy
- Furtado Joao M.
- Gad Mohamed M.
- Gaidhane Abhay Motiramji
- Gakidou Emmanuela
- Galles Natalie C.
- Gallus Silvano
- Gamkrelidze Amiran
- Garcia-Basteiro Alberto L.
- Gardner William M.
- Geberemariyam Biniyam Sahiledengle
- Gebrehiwot Abiyu Mekonnen
- Gebremedhin Ketema Bizuwork
- Gebremeskel Gebreamlak Gebremedhn
- Gebremeskel Leake G.
- Gebresillassie Begashaw Melaku
- Gebreslassie Assefa Ayalew Ayalew Ayalew
- Gela Jiregna Darega
- Geramo Yilma Chisha Dea
- Geremew Abraham
- Gesesew Hailay Abrha
- Gething Peter W.
- Gezae Kebede Embaye
- Ghadimi Maryam
- Ghadiri Keyghobad
- Ghaffarifar Fatemeh
- Ghafourifard Mansour
- Ghajar Alireza
- Ghamari Farhad
- Ghashghaee Ahmad
- Ghiasvand Hesam
- Ghith Nermin
- Gholamian Asadollah
- Ghosh Rakesh
- Giampaoli Simona
- Gilani Syed Amir
- Gill Paramjit Singh
- Gill Tiffany K.
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageed
- Ginindza Themba G.
- Gitimoghaddam Mojgan
- Giussani Giorgia
- Glagn Mustefa
- Glushkova Ekaterina Vladimirovna
- Gnedovskaya Elena V.
- Godinho Myron Anthony
- Goharinezhad Salime
- Golechha Mahaveer
- Goli Srinivas
- Gomez Ricardo Santiago
- Gona Philimon N.
- Gopalani Sameer Vali
- Goren Emily
- Gorini Giuseppe
- Gorman Taren M.
- Gottlich Harrison Chase
- Goudarzi Houman
- Goudarzian Amir Hossein
- Goulart Alessandra C.
- Goulart Barbara Niegia Garcia
- Grada Ayman
- Greaves Felix
- Grivna Michal
- Grosso Giuseppe
- Gubari Mohammed Ibrahim Mohialdeen
- Gudi Nachiket
- Gugnani Harish Chander
- Guimaraes Andre Luiz Sena
- Guimaraes Rafael Alves
- Guled Rashid Abdi
- Gultie Teklemariam
- Guo Gaorui
- Guo Yuming
- Gupta Rahul
- Gupta Rajeev
- Gupta Tarun
- Haagsma Juanita A.
- Hachinski Vladimir
- Haddock Beatrix
- Hafezi-Nejad Nima
- Hafiz Abdul
- Hagins Hailey
- Haile Lydia M.
- Haile Teklehaimanot Gereziher
- Haj-Mirzaian Arvin
- Haj-Mirzaian Arya
- Hall Brian J.
- Halvaei Iman
- Hamadeh Randah R.
- Hameed Sajid
- Hamidi Samer
- Hamilton Erin B.
- Hammer Melanie S.
- Han Chieh
- Han Hannah
- Handiso Demelash Woldeyohannes
- Hanif Asif
- Hankey Graeme J.
- Hanson Sarah Wulf
- Haririan Hamidreza
- Haro Josep Maria
- Harvey James D.
- Hasaballah Ahmed I.
- Hasan Md Mehedi
- Hasanpoor Edris
- Hasanzadeh Amir
- Hashemian Maryam
- Hashi Abdiwahab
- Hassan Amr
- Hassan Shoaib
- Hassanipour Soheil
- Hassankhani Hadi
- Havmoeller Rasmus J.
- Hawariat Feleke Gebremeskel W.
- Hay Roderick J.
- Hay Simon I.
- Hayat Khezar
- Hayoon Anna Gershberg
- Heibati Behzad
- Heidari Behnam
- Heidari Golnaz
- Heidari-Soureshjani Reza
- Hendrie Delia
- Henny Kiana
- Henok Andualem
- Henrikson Hannah J.
- Henry Nathaniel J.
- Herbert Molly E.
- Herrera Ana M. Mantilla
- Herteliu Claudiu
- Heydarpour Fatemeh
- Hird Thomas R.
- Ho Hung Chak
- Hoek Hans W.
- Hole Michael K.
- Holla Ramesh
- Hollingsworth Bruce
- Hoogar Praveen
- Hopf Kathleen Pillsbury
- Horita Nobuyuki
- Hosgood H. Dean
- Hossain Naznin
- Hosseini Mostafa
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Househ Mowafa
- Hoy Damian G.
- Hsairi Mohamed
- Hsiao Thomas
- Hsieh Vivian Chia-Rong
- Hu Guoqing
- Hu Kejia
- Huda Tanvir M.
- Hugo Fernando N.
- Humayun Ayesha
- Hussain Rabia
- Huynh Chantal K.
- Hwang Bing-Fang
- Iannucci Vincent C.
- Iavicoli Ivo
- Ibeneme Charles Ugochukwu
- Ibitoye Segun Emmanuel
- Ikeda Nayu
- Ikuta Kevin S.
- Il Shin Jae
- Ilesanmi Olayinka Stephen
- Ilic Irena M.
- Ilic Milena D.
- Imani-Nasab Mohammad Hasan
- Inbaraj Leeberk Raja
- Ippolito Helen
- Iqbal Usman
- Irvani Seyed Sina Naghibi
- Irvine Caleb Mackay Salpeter
- Islam M. Mofizul
- Islam MdMohaimenul
- Islam Sheikh Mohammed Shariful
- Islami Farhad
- Iso Hiroyasu
- Ivers Rebecca Q.
- Iwu Chidozie C. D.
- Iwu Chinwe Juliana
- Iyamu Ihoghosa Osamuyi
- Jaafari Jalil
- Jabbari Seyed Hossein Yahyazadeh
- Jacobsen Kathryn H.
- Jadidi-Niaragh Farhad
- Jafarabadi Mohammad Asghari
- Jafari Hussain
- Jafarinia Morteza
- Jahagirdar Deepa
- Jahani Mohammad Ali
- Jahanmehr Nader
- Jakovljevic Mihajlo
- Jalali Amir
- Jalilian Farzad
- James Spencer L.
- Janjani Hosna
- Janodia Manthan Dilipkumar
- Javaheri Tahereh
- Javidnia Javad
- Jayatilleke Achala Upendra
- Jeemon Panniyammakal
- Jenabi Ensiyeh
- Jha Ravi Prakash
- Jha Vivekanand
- Ji John S.
- Jia Peng
- Johansson Lars
- John Oommen
- John-Akinola Yetunde O.
- Johnson Catherine Owens
- Johnson Sarah Charlotte
- Jonas Jost B.
- Joo Tamas
- Joshi Ankur
- Joukar Farahnaz
- Jozwiak Jacek Jerzy
- Jurisson Mikk
- Kabir Ali
- Kabir Zubair
- Kafil Hossein Samadi
- Kalan Mohammad Ebrahimi
- Kalani Hamed
- Kalani Rizwan
- Kalankesh Leila R.
- Kalhor Rohollah
- Kalhori Reza Pourmirza
- Kamath Aruna M.
- Kamiab Zahra
- Kanchan Tanuj
- Kapoor Neeti
- Karanikolos Marina
- Karch Andre
- Karim Mohd Anisul
- Karimi Salah Eddin
- Karimi Seyed Asaad
- Karimi Seyed M.
- Karyani Ali Kazemi
- Kasa Ayele Semachew
- Kassa Getachew Mullu
- Kassebaum Nicholas J.
- Katikireddi Srinivasa Vittal
- Kawakami Norito
- Kayode Gbenga A.
- Keddie Suzanne H.
- Keiyoro Peter Njenga
- Keller Cathleen
- Kemmer Laura
- Kendrick Parkes J.
- Kereselidze Maia
- Khader Yousef Saleh
- Khafaie Morteza Abdullatif
- Khalid Nauman
- Khammarnia Mohammad
- Khan Ejaz Ahmad
- Khan Gulfaraz
- Khan Maseer
- Khaneghah Amin Mousavi
- Khang Young-Ho
- Khatab Khaled
- Khater Amir M.
- Khater Mona M.
- Khatib Mahalaqua Nazli
- Khayamzadeh Maryam
- Khazaei Salman
- Khazaie Habibolah
- Khodayari Mohammad Taghi
- Khoja Abdullah T.
- Khubchandani Jagdish
- Khundkar Roba
- Kianipour Neda
- Kieling Christian
- Kim Cho-Il
- Kim Daniel
- Kim Young-Eun
- Kim Yun Jin
- Kimokoti Ruth W.
- Kinfu Yohannes
- Kisa Adnan
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- Kissimova-Skarbek Katarzyna
- Kissoon Niranjan
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- Moghadam Telma Zahirian
- Moghadaszadeh Masoud
- Moghaddam Sahar Saeedi
- Mohajer Bahram
- Mohamad Osama
- Mohamadi Efat
- Mohammad Dara K.
- Mohammad Yousef
- Mohammadbeigi Abolfazl
- Mohammadian-Hafshejani Abdollah
- Mohammadifard Noushin
- Mohammadpourhodki Reza
- Mohammed Ammas Siraj
- Mohammed Hussen
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- Mohammed Shafiu
- Mohebi Farnam
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- Molokhia Mariam
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- Moradi Ghobad
- Moradi Masoud
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- Moradi-Lakeh Maziar
- Moradzadeh Rahmatollah
- Moraga Paula
- Morales Linda
- Morawska Lidia
- Morgado-da-Costa Joana
- Morrison Shane Douglas
- Mosapour Abbas
- Mosser Jonathan F.
- Motlagh Soraya Nouraei
- Mouodi Simin
- Mousavi Seyyed Meysam
- Mueller Ulrich Otto
- Mukhopadhyay Satinath
- Mullany Erin C.
- Mumford John Everett
- Munro Sandra B.
- Muriithi Moses K.
- Murray Christopher J. L.
- Musa Kamarul Imran
- Mustafa Ghulam
- Muthupandian Saravanan
- Nabavizadeh Behnam
- Nabhan Ashraf F.
- Naderi Mehdi
- Nagaraja Sharath Burugina
- Nagarajan Ahamarshan Jayaraman
- Nagel Gabriele
- Naghavi Mohsen
- Naghshtabrizi Behshad
- Naik Gurudatta
- Naimzada Mukhammad David
- Nair Sanjeev
- Najafi Farid
- Naldi Luigi
- Nandakumar Vishnu
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- Nangia Vinay
- Nansseu Jobert Richie
- Nasab Entezar Mehrabi
- Naserbakht Morteza
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- Nazari Javad
- Ndejjo Rawlance
- Ndwandwe Duduzile Edith
- Negoi Ionut
- Negoi Ruxandra Irina
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- Ngari Kiirithio N.
- Nguefack-Tsague Georges
- Ngunjiri Josephine W.
- Nguyen Cuong Tat
- Nguyen Diep Ngoc
- Nguyen Huong Lan Thi
- Nguyen Jason
- Nguyen Michele
- Nguyen Ming
- Nguyen Trang Huyen
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- Nigatu Dabere
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- Nikbakhsh Rajan
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- Nnaji Chukwudi A.
- Nomura Shuhei
- Norheim Ole F.
- Norrving Bo
- Noubiap Jean Jacques
- Nowak Christoph
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- Nunez-Samudio Virginia
- Oancea Bogdan
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- Ogbo Felix Akpojene
- Oghenetega Onome Bright
- Oh In-Hwan
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- Okunga Emmanuel Wandera
- Oladnabi Morteza
- Olagunju Andrew T.
- Olusanya Bolajoko Olubukunola
- Olusanya Jacob Olusegun
- Oluwasanu Mojisola Morenike
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- Oren Eyal
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- Ortiz Alberto
- Osarenotor Osayomwanbo
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- Otstavnov Nikita
- Otstavnov Stanislav S.
- Overland Simon
- Owolabi Mayowa O.
- Padubidri Jagadish Rao
- Pakhale Smita
- Pakhare Abhijit P.
- Pakshir Keyvan
- Palladino Raffaele
- Pana Adrian
- Panda-Jonas Songhomitra
- Pandey Anamika
- Pangaribuan Helena Ullyartha
- Park Eun-Kee
- Park James
- Parmar Priya G. Kumari
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- Pasovic Maja
- Pasupula Deepak Kumar
- Patel Jenil R.
- Patel Sangram Kishor
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- Pathak Ashish
- Pathak Mona
- Patten Scott B.
- Patton George C.
- Paudel Deepak
- Paudel Sagun
- Paulson Katherine R.
- Pease Spencer A.
- Peden Amy E.
- Pennini Alyssa
- Pepito Veincent Christian Filipino
- Peprah Emmanuel K.
- Pereira Alexandre
- Pereira David M.
- Pereira Jeevan
- Perico Norberto
- Pescarini Julia Moreira
- Pesudovs Konrad
- Pham Hai Quang
- Phillips Michael R.
- Piccinelli Cristiano
- Pierce Maxwell
- Pigott David M.
- Pilgrim Thomas
- Pilz Tessa M.
- Pinheiro Marina
- Piradov Michael A.
- Pirsaheb Meghdad
- Pishgar Farhad
- Plana-Ripoll Oleguer
- Plass Dietrich
- Pletcher Martin
- Pokhrel Khem Narayan
- Polibin Roman V.
- Polinder Suzanne
- Polkinghorne Kevan R.
- Pond Constance Dimity
- Postma Maarten J.
- Pottoo Faheem Hyder
- Pourjafar Hadi
- Pourmalek Farshad
- Pourshams Akram
- Poznanska Anna
- Prada Sergio I.
- Prakash Sanjay
- Prakash V.
- Prasad Narayan
- Preotescu Liliana
- Pribadi Dimas Ria Angga
- Pupillo Elisabetta
- Quazi Syed Zahiruddin
- Quintanilla Beatriz Paulina Ayala
- Rabiee Mohammad
- Rabiee Navid
- Radfar Amir
- Rafiee Ata
- Rafiei Alireza
- Raggi Alberto
- Rahim Fakher
- Rahimi-Movaghar Afarin
- Rahman Mohammad Hifz Ur
- Rahman Muhammad Aziz
- Rajabpour-Sanati Ali
- Rajati Fatemeh
- Rakovac Ivo
- Ram Pradhum
- Ramezanzadeh Kiana
- Rana Saleem Muhammad
- Ranabhat Chhabi Lal
- Ranta Annemarei
- Rao Puja C.
- Rao Sowmya J.
- Rasella Davide
- Rashedi Vahid
- Rastogi Prateek
- Rath Goura Kishor
- Rathi Priya
- Rawaf David Laith
- Rawaf Salman
- Rawal Lal
- Rawassizadeh Reza
- Rawat Ramu
- Razo Christian
- Regassa Lemma Demissie
- Reiner Robert C., Jr.
- Reinig Nickolas
- Reitsma Marissa Bettay
- Remuzzi Giuseppe
- Renjith Vishnu
- Renzaho Andre M. N.
- Resnikoff Serge
- Rezaei Negar
- Rezaei Nima
- Rezai Mohammad Sadegh
- Rezapour Aziz
- Rhinehart Phoebe-Anne
- Riahi Seyed Mohammad
- Ribeiro Antonio Luiz P.
- Ribeiro Daniel Cury
- Ribeiro Daniela
- Rickard Jennifer
- Rincon Julio Cesar Campuzano
- Rivera Juan A.
- Robalik Toshana
- Roberts Nicholas L. S.
- Roberts Shaun
- Robinson Stephen R.
- Rodriguez-Ramirez Sonia
- Roever Leonardo
- Rolfe Sam
- Romoli Michele
- Ronfani Luca
- Room Robin
- Roshandel Gholamreza
- Rostamian Morteza
- Roth Gregory A.
- Rothenbacher Dietrich
- Rubagotti Enrico
- Rumisha Susan Fred
- Rwegerera Godfrey M.
- Saadatagah Seyedmohammad
- Sabour Siamak
- Sachdev Perminder S.
- Saddik Basema
- Sadeghi Ehsan
- Sadeghi Masoumeh
- Saeedi Reza
- Saeidi Shahram
- Safari Yahya
- Safi Sare
- Safiri Saeid
- Sagar Rajesh
- Sahebkar Amirhossein
- Sahraian Mohammad Ali
- Sajadi S. Mohammad
- Salahshoor Mohammad Reza
- Salam Nasir
- Salama Joseph S.
- Salamati Payman
- Salem Hosni
- Salem Marwa R.
- Salimi Yahya
- Salimzadeh Hamideh
- Salman Omar Mukhtar
- Salomon Joshua A.
- Salz Inbal
- Samad Zainab
- Sambala Evanson Zondani
- Samy Abdallah M.
- Sanabria Juan
- Sanchez-Pimienta Tania G.
- Santomauro Damian Francesco
- Santos Itamar S.
- Santos Joao Vasco
- Santric-Milicevic Milena M.
- Saraswathy Sivan Yegnanarayana Iyer
- Sarmiento-Suarez Rodrigo
- Sarrafzadegan Nizal
- Sartorius Benn
- Sarveazad Arash
- Sathian Brijesh
- Sathish Thirunavukkarasu
- Sattin Davide
- Savic Miloje
- Sawyer Susan M.
- Saxena Deepak
- Saxena Sonia
- Saylan Mete
- Sbarra Alyssa N.
- Schaeffer Lauren E.
- Schiavolin Silvia
- Schlaich Markus P.
- Schmidt Maria Ines
- Schutte Aletta Elisabeth
- Schwebel David C.
- Schwendicke Falk
- Section Mahesh P. A.
- Seedat Soraya
- Sekerija Mario
- Senbeta Anbissa Muleta
- Senthilkumaran Subramanian
- Sepanlou Sadaf G.
- Serdar Berrin
- Serre Marc L.
- Servan-Mori Edson
- Sha Feng
- Shabani Mahsima
- Shackelford Katya Anne
- Shadid Jamileh
- Shafaat Omid
- Shahabi Saeed
- Shahbaz Mohammad
- Shaheen Amira A.
- Shaikh Masood Ali
- Shaji K. S.
- Shalash Ali S.
- Shams-Beyranvand Mehran
- Shamsi MohammadBagher
- Shamsizadeh Morteza
- Shannawaz Mohammed
- Sharafi Kiomars
- Sharafi Zeinab
- Sharan Subodh
- Sharara Fablina
- Sharifi Hamid
- Sharma Rajesh
- Shaw David H.
- Sheena Brittney S.
- Sheikh Aziz
- Sheikhtaheri Abbas
- Shetty B. Suresh Kumar
- Shetty Ranjitha S.
- Shibuya Kenji
- Shield Kevin David
- Shiferaw Wondimeneh Shibabaw
- Shigematsu Mika
- Shin Min-Jeong
- Shiri Rahman
- Shirkoohi Reza
- Shivakumar K. M.
- Shrime Mark G.
- Shuval Kerem
- Siabani Soraya
- Sierpinski Radoslaw
- Sigfusdottir Inga Dora
- Sigurvinsdottir Rannveig
- Silva Diego Augusto Santos
- Silva Joao Pedro
- Simonetti Biagio
- Simpson Kyle E.
- Singh Ambrish
- Singh Jasvinder A.
- Singh Pushpendra
- Sinha Dhirendra Narain
- Skiadaresi Eirini
- Skou Soren T.
- Skryabin Valentin Yurievich
- Sliwa Karen
- Smith Amanda
- Smith Emma U. R.
- Sobngwi Eugene
- Soheili Amin
- Sokhan Anton
- Soltani Shahin
- Somefun Oluwaseyi Dolapo
- Soofi Moslem
- Sorensen Reed J. D.
- Soriano Joan B.
- Sorrie Muluken Bekele
- Soshnikov Sergey
- Soyiri Ireneous N.
- Spencer Cory N.
- Spotin Adel
- Spurlock Emma Elizabeth
- Sreeramareddy Chandrashekhar T.
- Srinivasan Vinay
- Sripada Kam
- Stanaway Jeffrey D.
- Stark Benjamin A.
- Steel Nicholas
- Stefan Simona Catalina
- Stein Caroline
- Stein Dan J.
- Steiner Caitlyn
- Steiner Timothy J.
- Steuben Krista M.
- Stockfelt Leo
- Stokes Mark A.
- Stovner Lars Jacob
- Straif Kurt
- Stranges Saverio
- Stubbs Jacob L.
- Suchdev Parminder S.
- Sudaryanto Agus
- Sufiyan Mu'awiyyah Babale
- Suleria Hafiz Ansar Rasul
- Sulo Gerhard
- Sultan Iyad
- Swope Carolyn B.
- Sykes Bryan L.
- Sylte Dillon O.
- Szocska Miklos
- Szumowski Lukasz
- Tabares-Seisdedos Rafael
- Tabb Karen M.
- Tabuchi Takahiro
- Tadakamadla Santosh Kumar
- Taddele Biruk Wogayehu
- Tadesse Degena Bahrey
- Taherkhani Amir
- Tahir Zarfishan
- Tajdini Masih
- Takahashi Ken
- Takala Jukka S.
- Tamiru Animut Tagele
- Tang Muming
- Tanser Frank C.
- Tareque Md Ismail
- Tarigan Ingan Ukur
- Taveira Nuno
- Taylor Heather Jean
- Teagle Whitney L.
- Teame Hirut
- Tediosi Fabrizio
- Tefera Yonas Getaye
- Tehrani-Banihashemi Arash
- Teklehaimanot Berhane Fseha
- Tela Freweini Gebrearegay
- Temsah Mohamad-Hani
- Terrason Sonyah
- Tesema Getayeneh Antehunegn
- Tessema Zemenu Tadesse
- Thakur Bhaskar
- Thankappan Kavumpurathu Raman
- Thapar Rekha
- Thomas Nihal
- Thomson Azalea M.
- Thrift Amanda G.
- Thurston George D.
- Titova Mariya Vladimirovna
- Tlou Boikhutso
- Tohidinik Hamid Reza
- Tonelli Marcello
- Topor-Madry Roman
- Topouzis Fotis
- Toroudi Hamidreza Pazoki
- Torre Anna E.
- Touvier Mathilde
- Tovani-Palone Marcos Roberto
- Traini Eugenio
- Tran Bach Xuan
- Travillian Ravensara
- Trias-Llimos Sergi
- Troeger Christopher E.
- Truelsen Thomas Clement
- Tsai Alexander C.
- Tsatsakis Aristidis
- Tyrovolas Stefanos
- Uddin Riaz
- Ullah Irfan
- Ullah Saif
- Umeokonkwo Chukwuma David
- Undurraga Eduardo A.
- Unnikrishnan Bhaskaran
- Upadhyay Era
- Uthman Olalekan A.
- Vacante Marco
- Vaicekonyte Regina
- Vakilian Alireza
- Valdez Pascual R.
- Valli Alessandro
- Van Donkelaar Aaron
- Vardavas Constantine
- Varughese Santosh
- Vasankari Tommi Juhani
- Vasconcelos Ana Maria Nogales
- Vasseghian Yasser
- Veisani Yousef
- Velasquez Ilais Moreno
- Venketasubramanian Narayanaswamy
- Vidale Simone
- Violante Francesco S.
- Vlassov Vasily
- Vollset Stein Emil
- Vongpradith Avina
- Vos Theo
- Vu Giang Thu
- Vujcic Isidora S.
- Vukovic Ana
- Vukovic Rade
- Waheed Yasir
- Wallin Mitchell Taylor
- Walters Magdalene K.
- Wamai Richard G.
- Wang Fang
- Wang Haidong
- Wang Hongbo
- Wang Jiayu
- Wang Yafeng
- Wang Yanzhong
- Wang Yuan-Pang
- Ward Joseph L.
- Watson Alexandrea
- Watson Stefanie
- Wei Jingkai
- Wei Melissa Y. Wei
- Weintraub Robert G.
- Weiss Daniel J.
- Weiss Jordan
- Welay Fissaha Tekulu
- Weldesamuel Girmay Teklay
- Werdecker Andrea
- West J. Jason
- Westerman Ronny
- Whisnant Joanna L.
- Whiteford Harvey A.
- Wiangkham Taweewat
- Wickramasinghe Nuwan Darshana
- Wiens Kirsten E.
- Wijeratne Tissa
- Wilner Lauren B.
- Wilson Shadrach
- Wiysonge Charles Shey
- Wojtyniak Bogdan
- Woldu Gebremariam
- Wolfe Charles D. A.
- Wondmeneh Temesgen Gebeyehu
- Wondmieneh Adam Belay
- Wool Eve E.
- Wozniak Sarah S.
- Wu Ai-Min
- Wu Chenkai
- Wu Junjie
- Wunrow Han Yong
- Xie Yang
- Xu Gelin
- Xu Rixing
- Yadgir Simon
- Yamada Tomohide
- Yamagishi Kazumasa
- Yaminfirooz Mousa
- Yano Yuichiro
- Yaya Sanni
- Yazdi-Feyzabadi Vahid
- Yearwood Jamal A.
- Yeheyis Tomas Y.
- Yeshitila Yordanos Gizachew
- Yilgwan Christopher Sabo
- Yilma Mekdes Tigistu
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- York Hunter W.
- Younis Mustafa Z.
- Younker Theodore Patrick
- Yousefi Bahman
- Yousefi Zabihollah
- Yousefifard Mahmoud
- Yousefinezhadi Taraneh
- Yousuf Abdilahi Yousuf
- Yu Chuanhua
- Yu Yong
- Yuan Chun-Wei
- Yuce Deniz
- Yusefzadeh Hasan
- Zadey Siddhesh
- Zahabi Saleh Salehi
- Zaidi Syed Saoud
- Zaki Leila
- Zaki Maysaa El Sayed
- Zakzuk Josefina
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zangeneh Alireza
- Zarafshan Hadi
- Zastrozhin Mikhail Sergeevich
- Zewdie Kaleab Alemayehu
- Zhang Jianrong
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Jeff T.
- Zhao Xiu-Ju George
- Zhao Yingxi
- Zheleva Bistra
- Zheng Peng
- Zhou Maigeng
- Zhu Cong
- Ziapour Arash
- Zimsen Stephanie R. M.
- Zlavog Bianca S.
- Zodpey Sanjay
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens
Mapping routine measles vaccination in low- and middle-income countries
- Author
- Aaron E Osgood-Zimmerman (8383062)
- Abbas Azadmehr (12151653)
- Abbas Mosapour (9154247)
- Abbas Sheikhtaheri (9715088)
- Abdallah M Samy (8383428)
- Abdelrahman I Abushouk (9714446)
- Abdollah Mohammadian-Hafshejani (9714923)
- Abiy H Sinke (12150585)
- Abiyu Mekonnen Gebrehiwot (9715364)
- Abolfazl Mohammadbeigi (9715730)
- Adel Spotin (7384796)
- Adhanom Gebreegziabher Baraki (8595675)
- Adnan Kisa (6419198)
- Adrian Pana (5814992)
- Afsaneh Arzani (9153932)
- Agus Sudaryanto (1979845)
- Ahad Bakhtiari (6192659)
- Ahamarshan Jayaraman Nagarajan (9154253)
- Ahmad Ghashghaee (9154076)
- Ahmed Abdelalim (8673294)
- Ahmed I Hasaballah (9154109)
- Ahmed Omar Bali (9154271)
- Ai Koyanagi (430702)
- Ai-Min Wu (561245)
- Aisha Elsharkawy (9154031)
- Alaa Badawi (521535)
- Aleksandra Barac (8673444)
- Alem Girmay (8173929)
- Ali Almasi (9153917)
- Ali Bijani (8383632)
- Ali H Mokdad (8383332)
- Ali Kabir (9154145)
- Ali Kazemi Karyani (8383668)
- Ali S Shalash (9154358)
- Ali Yadollahpour (8674665)
- Alireza Ansari-Moghaddam (9714485)
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- Yuming Guo (162863)
- Yun Jin Kim (2133199)
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- Zemenu Tadesse Tessema (8383464)
- Zhi-Jiang Zhang (539386)
- Zubair Kabir (394455)
- Zul Kamal (6426083)
- Zulfiqar A Bhutta (8051936)
- Publication venue
- Publication date
- 21/01/2021
- Field of study
The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhood MCV1 coverage at 5 × 5-km2 pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati Cristiana
- Abbas Kaja M.
- Abbasi Mohammad
- Abbasi-Kangevari Mohsen
- Abbasifard Mitra
- Abbastabar Hedayat
- Abd El Razek Hassan Magdy
- Abd El Razek Muhammed Magdy
- Abd-Allah Foad
- Abdelalim Ahmed
- Abdollahi Mohammad
- Abdollahpour Ibrahim
- Abdulkader Rizwan Suliankatchi
- Abdullah Kanaan Hamagharib
- Abedi Aidin
- Abedi Parisa
- Abegaz Kedir Hussein
- Abolhassani Hassan
- Abosetugn Akine Eshete
- Aboyans Victor
- Abrams Elissa M.
- Abreu Lucas Guimaraes
- Abrigo Michael R. M.
- Abu Haimed Abdulaziz Khalid
- Abu-Gharbieh Eman
- Abu-Raddad Laith Jamal
- Abualhasan Ahmed
- Abushouk Abdelrahman I.
- Acebedo Alyssa
- Ackerman Ilana N.
- Adabi Maryam
- Adair Tim
- Adamu Abdu A.
- Adebayo Oladimeji M.
- Adedeji Isaac Akinkunmi
- Adekanmbi Victor
- Adelson Jaimie D.
- Adeoye Abiodun Moshood
- Adetokunboh Olatunji O.
- Adham Davoud
- Advani Shailesh M.
- Afarideh Mohsen
- Afshari Mahdi
- Afshin Ashkan
- Agardh Emilie E.
- Agarwal Gina
- Agasthi Pradyumna
- Agesa Kareha M.
- Aghaali Mohammad
- Aghamir Seyed Mohammad Kazem
- Agrawal Anurag
- Ahmad Tauseef
- Ahmadi Alireza
- Ahmadi Keivan
- Ahmadi Mehdi
- Ahmadieh Hamid
- Ahmadpour Ehsan
- Ahmed Muktar Beshir
- Aji Budi
- Akalu Temesgen Yihunie
- Akinyemi Rufus Olusola
- Akinyemiju Tomi
- Akombi Blessing
- Akunna Chisom Joyqueenet
- Al-Aly Ziyad
- Al-Mekhlafi Hesham M.
- Al-Raddadi Rajaa M.
- Alahdab Fares
- Alam Khurshid
- Alam Noore
- Alam Samiah
- Alam Tahiya
- Alanezi Fahad Mashhour
- Alanzi Turki M.
- Albertson Samuel B.
- Alcalde-Rabanal Jacqueline Elizabeth
- Alema Niguse Meles
- Alemu Biresaw Wassihun
- Alemu Yihun Mulugeta
- Alhabib Khalid F.
- Alhassan Robert Kaba
- Ali Muhammad
- Ali Saqib
- Alicandro Gianfranco
- Alijanzadeh Mehran
- Alinia Cyrus
- Alipour Vahid
- Alizade Hesam
- Aljunid Syed Mohamed
- Alla Francois
- Allebeck Peter
- Almadi Majid Abdulrahman Hamad
- Almasi Ali
- Almasi-Hashiani Amir
- Almasri Nihad A.
- Almulhim Abdulaziz M.
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- Alvis-Guzman Nelson
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- Amare Azmeraw T.
- Amare Bekalu
- Amini Saeed
- Amini-Rarani Mostafa
- Aminorroaya Arya
- Amiri Fatemeh
- Amit Arianna Maever L.
- Amugsi Dickson A.
- Amul Gianna Gayle Herrera
- Anbesu Etsay Woldu
- Ancuceanu Robert
- Anderlini Deanna
- Anderson Jason A.
- Andrei Catalina Liliana
- Andrei Tudorel
- Androudi Sofia
- Angus Colin
- Anjomshoa Mina
- Ansari Fereshteh
- Ansari Iman
- Ansari-Moghaddam Alireza
- Antonazzo Ippazio Cosimo
- Antonio Carl Abelardo T.
- Antony Catherine M.
- Antriyandarti Ernoiz
- Anvari Davood
- Anwer Razique
- Appiah Seth Christopher Yaw
- Arab-Zozani Morteza
- Arabloo Jalal
- Aravkin Aleksandr Y.
- Arba Aseb Arba Kinfe
- Aremu Olatunde
- Ariani Filippo
- Aripov Timur
- Armoon Bahram
- Arnlov Johan
- Arowosegbe Oluwaseyi Olalekan
- Aryal Krishna K.
- Arzani Afsaneh
- Asaad Malke
- Asadi-Aliabadi Mehran
- Asadi-Pooya Ali A.
- Asgari Samaneh
- Asghari Babak
- Ashbaugh Charlie
- Assmus Michael
- Atafar Zahra
- Athari Seyyed Shamsadin
- Atnafu Desta Debalkie
- Atout Maha Moh'd Wahbi
- Atre Sachin R.
- Atteraya Madhu Sudhan
- Ausloos Floriane
- Ausloos Marcel
- Avila-Burgos Leticia
- Avokpaho Euripide Frinel Gbenato Arthur
- Ayano Getinet
- Ayanore Martin Amogre
- Aynalem Getie Lake
- Aynalem Yared Asmare
- Ayza Muluken Altaye
- Azari Samad
- Azarian Ghasem
- Azene Zelalem Nigussie
- Azhar Gulrez
- Azzopardi Peter S.
- Babaee Ebrahim
- Badawi Alaa
- Badiye Ashish D.
- Bagherzadeh Mojtaba
- Bagli Eleni
- Bahrami Mohammad Amin
- Baig Atif Amin
- Bairwa Mohan
- Bakhshaei Mohammad Hossein
- Bakhtiari Ahad
- Bakkannavar Shankar M.
- Balachandran Arun
- Balakrishnan Senthilkumar
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- Balassyano Shelly
- Baldasseroni Alberto
- Bali Ahmed Omar
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- Ballew Shoshana H.
- Balzi Daniela
- Banach Maciej
- Bandpei Mohammad A. Mohseni
- Banerjee Srikanta K.
- Banik Palash Chandra
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- Bante Agegnehu Bante
- Bante Simachew Animen
- Baraki Adhanom Gebreegziabher
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- Barker-Collo Suzanne Lyn
- Barnighausen Till Winfried
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- Barthelemy Celine M.
- Barua Lingkan
- Barzegar Akbar
- Basaleem Huda
- Bassat Quique
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- Bayati Mohsen
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- Berman Adam E.
- Bernabe Eduardo
- Bernstein Robert S.
- Bertolacci Gregory J.
- Bhagavathula Akshaya Srikanth
- Bhageerathy Reshmi
- Bhala Neeraj
- Bhandari Dinesh
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- Bhattacharyya Krittika
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- Biehl Molly H.
- Bijani Ali
- Bikbov Boris
- Bilano Ver
- Bin Sayeed Muhammad Shahdaat
- Bin Zaman Sojib
- Biondi Antonio
- Birihane Binyam Minuye
- Bisanzio Donal
- Bisignano Catherine
- Biswas Raaj Kishore
- Bitew Helen
- Bjorge Tone
- Bockarie Moses John
- Bohlouli Somayeh
- Bohluli Mehdi
- Bojia Hunduma Amensisa
- Bolla Srinivasa Rao
- Boloor Archith
- Boon-Dooley Alexandra S.
- Borges Guilherme
- Borzi Antonio Maria
- Borzouei Shiva
- Bose Dipan
- Bosetti Cristina
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- Braithwaite Dejana
- Brauer Michael
- Brayne Carol
- Breitborde Nicholas J. K.
- Breitner Susanne
- Brenner Hermann
- Breusov Alexey V.
- Briant Paul Svitil
- Briggs Andrew M.
- Briko Andrey Nikolaevich
- Briko Nikolay Ivanovich
- Britton Gabrielle B.
- Brugha Traolach
- Bryazka Dana
- Buchbinder Rachelle
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- Burnett Richard Thomas
- Busse Reinhard
- Butt Zahid A.
- Caetano dos Santos Florentino Luciano
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- Cai Tianji
- Callender Charlton S. K. H.
- Camera Luis Alberto
- Campos-Nonato Ismael R.
- Cao Jackie
- Car Josip
- Car Lorainne Tudor
- Cardenas Rosario
- Carreras Giulia
- Carrero Juan J.
- Carvalho Felix
- Castaldelli-Maia Joao Mauricio
- Castaneda-Orjuela Carlos A.
- Castelpietra Giulio
- Castle Chris D.
- Castro Emma
- Castro Franz
- Catala-Lopez Ferran
- Causey Kate
- Cederroth Christopher R.
- Cercy Kelly M.
- Cerin Ester
- Chalek Julian
- Chandan Joht Singh
- Chang Alex R.
- Chang Angela Y.
- Chang Jung-Chen
- Chang Kai-Lan
- Charan Jaykaran
- Charlson Fiona J.
- Chattu Vijay Kumar
- Chaturvedi Sarika
- Cherbuin Nicolas
- Chimed-Ochir Odgerel
- Chin Ken Lee
- Chirinos-Caceres Jesus Lorenzo
- Cho Daniel Youngwhan
- Choi Jee-Young Jasmine
- Christensen Hanne
- Chu Dinh-Toi
- Chung Michael T.
- Chung Sheng-Chia
- Cicuttini Flavia M.
- Ciobanu Liliana G.
- Cirillo Massimo
- Cislaghi Beniamino
- Classen Thomas Khaled Dwayne
- Cohen Aaron J.
- Collins Emma L.
- Comfort Haley
- Compton Kelly
- Conti Sara
- Cooper Owen R.
- Corso Barbara
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Cousin Ewerton
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- Cowie Benjamin C.
- Cromwell Elizabeth A.
- Croneberger Andrew J.
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- Crowe Christopher Stephen
- Cruz Jessica A.
- Cummins Steven
- Cunningham Matthew
- D'Amico Emanuele
- da Silva Diana Dias
- Dahlawi Saad M. A.
- Dai Haijiang
- Dai Hancheng
- Damasceno Albertino Antonio Moura
- Damiani Giovanni
- Dandona Lalit
- Dandona Rakhi
- Daneshpajouhnejad Parnaz
- Dangel William James
- Danielsson Anna-Karin
- Dargan Paul I.
- Darshan B. B.
- Darwesh Aso Mohammad
- Daryani Ahmad
- Das Gupta Rajat
- Das Neves Jose
- Das Jai K.
- Dash Aditya Prasad
- Davey Gail
- Davila-Cervantes Claudio Alberto
- Davis Adrian C.
- Davitoiu Dragos Virgil
- Davletov Kairat
- De Leo Diego
- De Neve Jan-Walter
- Dean Frances E.
- DeCleene Nicole K.
- Deen Amanda
- Defo Barthelemy Kuate
- Degenhardt Louisa
- DeLang Marissa
- Dellavalle Robert Paul
- Demeke Feleke Mekonnen
- Demoz Gebre Teklemariam
- Demsie Desalegn Getnet
- Denova-Gutierrez Edgar
- Dereje Nebiyu Dereje
- Deribe Kebede
- Dervenis Nikolaos
- Desai Rupak
- Desalew Assefa
- Dessie Getenet Ayalew
- Deuba Keshab
- Dharmaratne Samath Dhamminda
- Dhungana Govinda Prasad
- Dianatinasab Mostafa
- Diaz Daniel
- Dichgans Martin
- Didarloo Alireza
- Dingels Zachary V.
- Dippenaar Ilse N.
- Dirac M. Ashworth
- Djalalinia Shirin
- Do Hoa Thi
- Dokova Klara
- Doku David Teye
- Dolecek Christiane
- Dolgert Andrew J.
- Dorostkar Fariba
- Doshi Chirag P.
- Doshi Pratik P.
- Doshmangir Leila
- Douiri Abdel
- Doxey Matthew C.
- Doyle Kerrie E.
- Driscoll Tim Robert
- Dubljanin Eleonora
- Dunachie Susanna J.
- Duncan Bruce B.
- Duraes Andre Rodrigues
- Eagan Arielle Wilder
- Ebrahimi Hedyeh
- Edvardsson David
- Effiong Andem
- Ehrlich Joshua R.
- El Nahas Nevine
- El Sayed Iman
- El Tantawi Maha
- El-Jaafary Shaimaa I.
- Elbarazi Iffat
- Elgendy Islam Y.
- Elhabashy Hala Rashad
- Elsharkawy Aisha
- Elyazar Iqbal R. F.
- Emamian Mohammad Hassan
- Emmons-Bell Sophia
- Erskine Holly E.
- Eshrati Babak
- Eskandari Khalil
- Eskandarieh Sharareh
- Esmaeilnejad Saman
- Esmaeilzadeh Firooz
- Esteghamati Alireza
- Esteghamati Sadaf
- Estep Kara
- Etemadi Arash
- Etisso Atkilt Esaiyas
- Ezekannagha Oluchi
- Fanzo Jessica
- Farag Tamer
- Farahmand Mohammad
- Faraj Anwar
- Faraon Emerito Jose A.
- Fareed Mohammad
- Faridnia Roghiyeh
- Farinha Carla Sofia e Sa
- Farioli Andrea
- Faris Pawan Sirwan
- Faro Andre
- Faruque Mithila
- Farzadfar Farshad
- Fattahi Nazir
- Fazaeli Ali Akbar
- Fazlzadeh Mehdi
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- Fernandes Eduarda
- Ferrara Giannina
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- Fisher James L.
- Fitzgerald Ryan
- Flohr Carsten
- Flor Luisa Sorio
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- Fomenkov Artem Alekseevich
- Force Lisa M.
- Fornari Carla
- Forooshani Zahra Sadat Dibaji
- Foroutan Masoud
- Fox Jack T.
- Francis Joel Msafiri
- Frank Tahvi D.
- Franklin Richard Charles
- Freitas Marisa
- Fu Weijia
- Fukumoto Takeshi
- Fukutaki Kai
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- Fullman Nancy
- Furtado Joao M.
- Gad Mohamed M.
- Gaidhane Abhay Motiramji
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- Gallus Silvano
- Gamkrelidze Amiran
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- Geberemariyam Biniyam Sahiledengle
- Gebrehiwot Abiyu Mekonnen
- Gebremedhin Ketema Bizuwork
- Gebremeskel Gebreamlak Gebremedhn
- Gebremeskel Leake G.
- Gebresillassie Begashaw Melaku
- Gebreslassie Assefa Ayalew Ayalew Ayalew
- Gela Jiregna Darega
- Geramo Yilma Chisha Dea
- Geremew Abraham
- Gesesew Hailay Abrha
- Gething Peter W.
- Gezae Kebede Embaye
- Ghadimi Maryam
- Ghadiri Keyghobad
- Ghaffarifar Fatemeh
- Ghafourifard Mansour
- Ghajar Alireza
- Ghamari Farhad
- Ghashghaee Ahmad
- Ghiasvand Hesam
- Ghith Nermin
- Gholamian Asadollah
- Ghosh Rakesh
- Giampaoli Simona
- Gilani Syed Amir
- Gill Paramjit Singh
- Gill Tiffany K.
- Gillum Richard F.
- Ginawi Ibrahim Abdelmageed
- Ginindza Themba G.
- Gitimoghaddam Mojgan
- Giussani Giorgia
- Glagn Mustefa
- Global Burden Dis
- Glushkova Ekaterina Vladimirovna
- Gnedovskaya Elena V.
- Godinho Myron Anthony
- Goharinezhad Salime
- Golechha Mahaveer
- Goli Srinivas
- Gomez Ricardo Santiago
- Gona Philimon N.
- Gopalani Sameer Vali
- Goren Emily
- Gorini Giuseppe
- Gorman Taren M.
- Gottlich Harrison Chase
- Goudarzi Houman
- Goudarzian Amir Hossein
- Goulart Alessandra C.
- Goulart Barbara Niegia Garcia
- Grada Ayman
- Greaves Felix
- Grivna Michal
- Grosso Giuseppe
- Gubari Mohammed Ibrahim Mohialdeen
- Gudi Nachiket
- Gugnani Harish Chander
- Guimaraes Andre Luiz Sena
- Guimaraes Rafael Alves
- Guled Rashid Abdi
- Gultie Teklemariam
- Guo Gaorui
- Guo Yuming
- Gupta Rahul
- Gupta Rajeev
- Gupta Tarun
- Haagsma Juanita A.
- Hachinski Vladimir
- Haddock Beatrix
- Hafezi-Nejad Nima
- Hafiz Abdul
- Hagins Hailey
- Haile Lydia M.
- Haile Teklehaimanot Gereziher
- Haj-Mirzaian Arvin
- Haj-Mirzaian Arya
- Hall Brian J.
- Halvaei Iman
- Hamadeh Randah R.
- Hameed Sajid
- Hamidi Samer
- Hamilton Erin B.
- Hammer Melanie S.
- Han Chieh
- Han Hannah
- Handiso Demelash Woldeyohannes
- Hanif Asif
- Hankey Graeme J.
- Hanson Sarah Wulf
- Haririan Hamidreza
- Haro Josep Maria
- Harvey James D.
- Hasaballah Ahmed I.
- Hasan Md Mehedi
- Hasanpoor Edris
- Hasanzadeh Amir
- Hashemian Maryam
- Hashi Abdiwahab
- Hassan Amr
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- Hassankhani Hadi
- Havmoeller Rasmus J.
- Hawariat Feleke Gebremeskel W.
- Hay Roderick J.
- Hay Simon I.
- Hayat Khezar
- Hayoon Anna Gershberg
- Heibati Behzad
- Heidari Behnam
- Heidari Golnaz
- Heidari-Soureshjani Reza
- Hendrie Delia
- Henny Kiana
- Henok Andualem
- Henrikson Hannah J.
- Henry Nathaniel J.
- Herbert Molly E.
- Herrera Ana M. Mantilla
- Herteliu Claudiu
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- Yeshitila Yordanos Gizachew
- Yilgwan Christopher Sabo
- Yilma Mekdes Tigistu
- Yip Paul
- Yonemoto Naohiro
- Yoon Seok-Jun
- York Hunter W.
- Younis Mustafa Z.
- Younker Theodore Patrick
- Yousefi Bahman
- Yousefi Zabihollah
- Yousefifard Mahmoud
- Yousefinezhadi Taraneh
- Yousuf Abdilahi Yousuf
- Yu Chuanhua
- Yu Yong
- Yuan Chun-Wei
- Yuce Deniz
- Yusefzadeh Hasan
- Zadey Siddhesh
- Zahabi Saleh Salehi
- Zaidi Syed Saoud
- Zaki Leila
- Zaki Maysaa El Sayed
- Zakzuk Josefina
- Zamani Mohammad
- Zamanian Maryam
- Zandian Hamed
- Zangeneh Alireza
- Zarafshan Hadi
- Zastrozhin Mikhail Sergeevich
- Zewdie Kaleab Alemayehu
- Zhang Jianrong
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Jeff T.
- Zhao Xiu-Ju George
- Zhao Yingxi
- Zheleva Bistra
- Zheng Peng
- Zhou Maigeng
- Zhu Cong
- Ziapour Arash
- Zimsen Stephanie R. M.
- Zlavog Bianca S.
- Zodpey Sanjay
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2020
- Field of study