Designing Public Transport To Foster Patronage And Social Inclusion

Institute of Transport and Logistics Studies. Faculty of Economics and Business. The University of Sydne

Кіноніми Кіровоградщини: особливості вибору кличок та способи їх творення

Стаття присвячена вивченню особливостей української кінонімії. Основну увагу зосереджено на дослідженні процесу номінації та способів словотворення кличок собак. Окремо розглянуто офіційні назви тварин, які мають родослівну.Статья посвящена изучению особенностей украинской кинонимии. Основное внимание сосредоточено на изучении процесса номинации и способах словообразования кличек собак. Отдельно рассмотрены официальные названия собак, имеющих родословную.The article is devoted to the research of the peculiarities of Ukrainian cynonymy. Most attention is taid to the research of the process of nomination and to the ways of formation of dogs' names. Special consideration is given to the official names of the animals with genealogy

“In-situ” lipase-catalyzed cotton coating with polyesters from ethylene glycol and glycerol

"Available online 12 January 2018"Several polyesters were synthesized from ethylene glycol, glycerol and adipate, succinate dimethyl esters. Immobilized Candida antarctica lipase B was used as catalyst for 6hours under vacuum at 70°C without any further solvents. The highest conversion rate of 88.5% occurred for the polymerization of poly (ethylene adipate), evaluated by 1H NMR. MALDI-TOF analysis indicated that most of the oligomers formed were dimers or trimers. After successfully synthesize the polyesters we set-up the optimal conditions for their in-situ coating onto cotton substrates with a soluble lipase from Thermomyces lanuginosus. This work presents a novel bio-approach to impart hydrophobic properties to coated cotton-based fiber materials.This work was supported by Chinese government scholarship under the State Scholarship Fund (grant number 201706790049), Jiangsu Province Scientific Research Innovation Project for Academic Graduate Students (grant number KYLX16_0788), Training Fund for Excellent Doctoral Student in Jiangnan University, Key Projects of governmental cooperation in international scientific and technological innovation (grant number 2016 YFE0115700) and the National Key R & D Program of China (grant number 2017 YFB0309100). This work was also supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (grant number POCI-01-0145-FEDER-006684) and under the Project RECI/BBB-EBI/0179/2012 (grant number FCOMP01-0124-FEDER-027462). This study was also supported by BioTecNorte operation (grant number NORTE-01-0145-FEDER000004) funded by the European Regional Development Fund under the scope of Norte2020 – Programa Operacional Regional do Norte. This work was also supported by the National Natural Science Foundation of China (grant number 31470509 and 31201134), the Industry-Academic Joint Technological Prospective Fund Project of Jiangsu Province (grant number BY2013015-24 and BY2016022-23), the fundamental research funds for the central universities (grant number JUSRP 51622A), and a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.info:eu-repo/semantics/publishedVersio

Development of lyophilized spherical particles of poly(epsilon-caprolactone) and examination of their morphology, cytocompatibility and influence on the formation of reactive oxygen species

A common limitation of using polymeric micro- and nanoparticles in long-term conservation is due to their poor physical and chemical stability. Freeze-drying is one of the most convenient methods that enable further reconstitution of micro- and nanoparticles for therapeutical use. Nevertheless, this process generates various stresses during freezing and desiccation steps. This paper underlines the combined outcomes of freeze drying method and physicochemical solvent/non-solvent approach to design biocompatible poly(epsilon-caprolactone) (PCL) nanospheres and evaluate influence of different cryoprotectants (glucose, saccharose, polyvinyl alcohol or polyglutamic acid) on the outcome of freeze-dried PCL particles. Samples were characterized using Fourier transform infrared spectroscopy (FT-IR). scanning electron microscopy (SEM) and dynamic light scattering method (DLS). In vitro studies used, include MTT assay (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide). testing cytotoxicity as the quality of being toxic to cells, and DCFH-DA assay (2',7'-dichlordihydrofluorescein-diacetate), testing the possible increase in ROS levels. It was found that cryoprotection with 1% glucose solution is an optimal for obtaining uniform, spherical but also biocompatible PCL nanoparticles for biomedical purposes

Thermally-activated shape memory effect on biodegradable nanocomposites based on PLA/PCL blend reinforced with hydroxyapatite

[EN] In this work, the effect of the addition of different amount of nanosized hydroxyapatite (nHA) on the shape memory behavior of blends based on poly (lactic acid) (PLA) and poly (epsilon-caprolactone) (PCL) has been studied. In particular PLA/PCL blend with 70 wt % PLA has been reinforced with 0.5, 1 and 3 wt % nHA. Moreover, the relationship between the morphology and the final properties of the nanocomposites has been investigated by field emission scanning electron microscopy, confocal Raman spectroscopy and atomic force microscopy. In particular, PeakForce has been used to study quantitative nanomechanical properties of the multifunctional materials leading to conclusion that nHA increase the phase separation between PLA and PCL as well as act as reinforcements for the PCL-rich phase of the nanocomposites. Furthermore, excellent thermally-activated shape memory response has been obtained for all the nanocomposites at 55 degrees C. Finally, the disintegration under composting conditions at laboratory scale level was studied in order to confirm the biodegradable character of these nanocomposites. Indeed, these materials are able to be used for biomedical issues as well as for packaging applications where both thermally-activated shape memory effect and biodegradability are requested.Authors thank the Spanish Ministry of Economy, Industry and Competitiveness, MINEICO, (MAT2017-88123-P) and the Regional Government of Madrid (S2013/MIT-2862) for the economic support. M.P.A. and L.P. acknowledge the Juan de la Cierva (FJCI-2014-20630) and Ramon y Cajal (RYC-2014-15595) contracts from the MINEICO, respectively. The authors also thanks CSIC for the I-Link project (I-Link1149).Peponi, L.; Sessini, V.; Arrieta, MP.; Navarro-Baena, I.; Sonseca Olalla, Á.; Dominici, F.; Giménez Torres, E.... (2018). Thermally-activated shape memory effect on biodegradable nanocomposites based on PLA/PCL blend reinforced with hydroxyapatite. Polymer Degradation and Stability. 151:36-51. https://doi.org/10.1016/j.polymdegradstab.2018.02.019S365115

Aluminum salen and salan complexes in the ring-opening polymerization of cyclic esters: Controlled immortal and copolymerization of <em>rac</em>-β-butyrolactone and <em>rac</em>-lactide

Aluminum-based salen and salan complexes mediate the ring-opening polymerization (ROP) of rac-β-butyrolactone (β-BL), rac-lactide, and ε-caprolactone. Al-salen and Al-salan complexes exhibit excellent control over the ROP of rac-β-butyrolactone, yielding atactic poly(3-hydroxybutyrate) (PHB) with narrow PDIs of <1.15 for Al-salen and <1.05 for Al-salan. Kinetic studies reveal pseudo-first-order polymerization kinetics and a linear relationship between molecular weight and percent conversion. These complexes also mediate the immortal ROP of rac-β-BL and rac-lactide, through the addition of excess benzyl alcohol of up to 50 mol eq., with excellent control observed. A novel methyl/adamantyl-substituted Al-salen system further improves control over the ROP of rac-lactide and rac-β-BL, yielding atactic PHB and highly isotactic poly(lactic acid) (Pm = 0.88). Control over the copolymerization of rac-lactide and rac-β-BL was also achieved, yielding poly(lactic acid)-co-poly(3-hydroxybutyrate) with narrow PDIs of <1.10. 1H NMR spectra of the copolymers indicate a strong bias for the insertion of rac-lactide over rac-β-BL

Recent approaches in designing bioadhesive materials inspired by mussel adhesive protein

Marine mussels secret protein-based adhesives, which enable them to anchor to various surfaces in a saline, intertidal zone. Mussel foot proteins (Mfps) contain a large abundance of a unique, catecholic amino acid, Dopa, in their protein sequences. Catechol offers robust and durable adhe-sion to various substrate surfaces and contributes to the curing of the adhesive plaques. In this article, we review the unique features and the key functionalities of Mfps, catechol chemistry, and strategies for preparing catechol-functionalized poly- mers. Specifically, we reviewed recent findings on the contributions of various features of Mfps on interfacial binding, which include coacervate formation, surface drying properties, control of the oxidation state of catechol, among other features. We also summarized recent developments in designing advanced biomimetic materials including coacervate-forming adhesives, mechanically improved nano- and micro-composite adhesive hydrogels, as well as smart and self-healing materials. Finally, we review the applications of catechol-functionalized materials for the use as biomedical adhesives, therapeutic applications, and antifouling coatings