9 research outputs found
Modern Security Screening and Electromagnetic Interference With Cardiac Implantable Electronic Devices
Synthesis and characterisation of hetero-bimetallic organometallic phenylalanine and PNA monomer derivatives
Security millimetre wave body scanner safe for patients with leadless pacemakers or subcutaneous implantable cardioverter-defibrillators
Phosphorus recovery from municipal wastewater: An integrated comparative technological, environmental and economic assessment of P recovery technologies
The incidence, indications and predictors of acute pacemaker implantation after ablation of persistent atrial fibrillation
Agronomic efficiency of selected phosphorus fertilisers derived from secondary raw materials for European agriculture. A meta-analysis
Experimental analysis of thermo-acoustic instabilities in a generic gas turbine combustor by phase-correlated PIV, chemiluminescence, and laser Raman scattering measurements
Human pathogenic streptococcal proteomics and vaccine development
Gram-positive streptococci are non-motile, chain-forming bacteria commonly found in the normal oral and bowel flora of warm-blooded animals. Over the past decade, a proteomic approach combining 2-DE and MS has been used to systematically map the cellular, surface-associated and secreted proteins of human pathogenic streptococcal species. The public availability of complete streptococcal genomic sequences and the amalgamation of proteomic, genomic and bioinformatic technologies have recently facilitated the identification of novel streptococcal vaccine candidate antigens and therapeutic agents. The objective of this review is to examine the constituents of the streptococcal cell wall and secreted proteome, the mechanisms of transport of surface and secreted proteins, and describe the current methodologies employed for the identification of novel surface-displayed proteins and potential vaccine antigens