Fit für die Konzeption von E-Learning-Angeboten: Eine praktische Online-Einführung für Angestellte in Bibliotheken

Die vorliegende Arbeit befasst sich mit der Konzeption und Erstellung von E-Learning-Angeboten in Bibliotheken. Im Zuge der Digitalisierung verändert sich das Verhalten von Bibliotheksnutzern. Der Bedarf nach E-Learning-Angeboten in Bibliotheken steigt. Das tatsächliche Angebot der Bibliotheken wird diesem steigenden Bedarf jedoch nicht gerecht. Insbesondere werden die Frage nach möglichen Gründen für das mangelnde Angebot und die Bedarfe der Angestellten in Bibliotheken in diesem Bereich genauer betrachtet. Nach der theoretischen Auseinandersetzung mit den Themen Informationskompetenz und E-Learning an Hochschulen folgt der empirische Teil der Arbeit. In Form einer Onlineumfrage wurden u.a. die Kompetenzen und Bedarfe sowie zeitliche und finanzielle Rahmenbedingungen der Angestellten im Bereich der Konzeption und Erstellung von E-Learning-Angeboten erfasst. Zudem wurden die Angestellten zum aktuellen Angebot von E-Learning an der Bibliothek, in der sie tätig sind, befragt. Über die Hälfte der befragten Angestellten gab an, dass in der Bibliothek, in der sie tätig sind, keinerlei E-Learning-Angebote zur Verfügung stehen. Gründe hierfür sind nach Angabe der Befragten in erster Linie die zeit- und arbeitsintensive Erstellung sowie die aufwändige Pflege von E-Learning-Angeboten. Als Ziel der Arbeit wurde unter Einbeziehung der konkret ermittelten Bedarfe von 327 Angestellten in Bibliotheken eine Online-Einführung konzipiert und in Form eines Erklärvideos umgesetzt. Das Video beantwortet die wichtigsten Fragen bei der Konzeption und Erstellung von E-Learning-Angeboten und soll somit die Schwelle zur Erstellung solcher Angebote verringern. Hier der Link zu dem Video auf Youtube: https://youtu.be/M7st4sgl2x

O Consumidor e a Constituição - 30 anos.

O presente artigo aborda a instituição do Direito do Consumidor decorrente da promulgação da Constituição Federal de 1988, que estabeleceu normas de proteção e defesa do consumidor de ordem publica e interesse social, nos termos dos art. 5º, inciso XXXII, art. 170, inciso 5º e o art. 48 e suas disposições transitórias, com cláusula pétrea. Discorrida rápida referência ao surgimento do CDC, aborda-se sobre a politica nacional da relação de consumo; da qualidade da vida do consumidor; dos seus princípios e da qualidade institucional dos serviços públicos oferecidos ao cidadão consumidor

Autosomal dominant hereditary spastic paraplegia: Novel mutations in the REEP1 gene (SPG31)

<p>Abstract</p> <p>Background</p> <p>Mutations in the <it>SPG4 </it>gene (spastin) and in the <it>SPG3A </it>gene (atlastin) account for the majority of 'pure' autosomal dominant form of hereditary spastic paraplegia (HSP). Recently, mutations in the <it>REEP1 </it>gene were identified to cause autosomal dominant HSP type SPG31. The purpose of this study was to determine the prevalence of <it>REEP1 </it>mutations in a cohort of 162 unrelated Caucasian index patients with 'pure' HSP and a positive family history (at least two persons per family presented symptoms).</p> <p>Methods</p> <p>162 patients were screened for mutations by, both, DHPLC and direct sequencing.</p> <p>Results</p> <p>Ten mutations were identified in the <it>REEP1 </it>gene, these included eight novel mutations comprising small insertions/deletions causing frame shifts and subsequently premature stop codons, one nonsense mutation and one splice site mutation as well as two missense mutations. Both missense mutations and the splice site mutation were not identified in 170 control subjects.</p> <p>Conclusion</p> <p>In our HSP cohort we found pathogenic mutations in 4.3% of cases with autosomal dominant inheritance. Our results confirm the previously observed mutation range of 3% to 6.5%, respectively, and they widen the spectrum of <it>REEP1 </it>mutations.</p

Causal Agents of Hop Dying

Stockfaule Hopfenpflanzen im Hopfenanbaugebiet Spalt bei Nürnberg weisen Befall mit dem Gefäßparasiten Ceratocystis paradoxa auf. Aus Bodenproben von über 100-jährigen Hopfengärten konnten die Pilze Fusarium oxysporum und F. equiseti isoliert werden. Bei der mikroskopischen Untersuchung von Hopfenwurzeln wurden Pilze der Gattungen Rhizoctonia und Pythium gefunden, die als Wurzelfäule-Erreger bekannt sind. An Faserwurzeln war starker Befall mit Hopfen-Zystennematoden (Heterodera humili), sowie an Haarwurzeln Befall mit Strahlenpilzen (Actinomycetes) zu erkennen, die für Bodenmüdigkeitserscheinungen verantwortlich sind.Rotten hop-stocks in the hop growing area of Spalt near Nuremberg were attacked by the vessels-invading fungus Ceratocystis paradoxa. The fungi Fusarium oxysporum and F. equiseti could be isolated from soil of a 100 years old hop garden. By microscopic examination, fungi of the genera Rhizoctonia and Pythium were found, which are known as root rot pathogens. The filamentous roots were severely attacked by hop cyst nematodes (Heterodera humili), and the hairy roots were infested with Actinomycetes, both responsible for the soil exhaustion syndrom

The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

BACKGROUND: Sleep difficulties might be a contributory causal factor in the occurrence of mental health problems. If this is true, improving sleep should benefit psychological health. We aimed to determine whether treating insomnia leads to a reduction in paranoia and hallucinations. METHODS: We did this single-blind, randomised controlled trial (OASIS) at 26 UK universities. University students with insomnia were randomly assigned (1:1) with simple randomisation to receive digital cognitive behavioural therapy (CBT) for insomnia or usual care, and the research team were masked to the treatment. Online assessments took place at weeks 0, 3, 10 (end of therapy), and 22. The primary outcome measures were for insomnia, paranoia, and hallucinatory experiences. We did intention-to-treat analyses. The trial is registered with the ISRCTN registry, number ISRCTN61272251. FINDINGS: Between March 5, 2015, and Feb 17, 2016, we randomly assigned 3755 participants to receive digital CBT for insomnia (n=1891) or usual practice (n=1864). Compared with usual practice, the sleep intervention at 10 weeks reduced insomnia (adjusted difference 4·78, 95% CI 4·29 to 5·26, Cohen's d=1·11; p<0·0001), paranoia (-2·22, -2·98 to -1·45, Cohen's d=0·19; p<0·0001), and hallucinations (-1·58, -1·98 to -1·18, Cohen's d=0·24; p<0·0001). Insomnia was a mediator of change in paranoia and hallucinations. No adverse events were reported. INTERPRETATION: To our knowledge, this is the largest randomised controlled trial of a psychological intervention for a mental health problem. It provides strong evidence that insomnia is a causal factor in the occurrence of psychotic experiences and other mental health problems. Whether the results generalise beyond a student population requires testing. The treatment of disrupted sleep might require a higher priority in mental health provision. FUNDING: Wellcome Trust

Suicide trends in the early months of the COVID-19 pandemic: an interrupted time-series analysis of preliminary data from 21 countries

BackgroundThe COVID-19 pandemic is having profound mental health consequences for many people. Concerns have been expressed that at its most extreme, this may manifest itself in increased suicide rates.MethodsWe sourced real-time suicide data from around the world via a systematic internet search and recourse to our networks and the published literature. We used interrupted time series analysis to model the trend in monthly suicides prior to COVID-19 in each country/area-within-country, comparing the expected number of suicides derived from the model with the observed number of suicides in the early months of the pandemic. Countries/areas-within countries contributed data from at least 1 January 2019 to 31 July 2020 and potentially from as far back as 1 January 2016 until as recently as 31 October 2020. We conducted a primary analysis in which we treated 1 April to 31 July 2020 as the COVID-19 period, and two sensitivity analyses in which we varied its start and end dates (for those countries/areas-within-countries with data beyond July 2020).OutcomesWe sourced data from 21 countries (high income [n=16], upper-middle income [n=5]; whole country [n=10], area(s)-within-the-country [n=11]). In general, there does not appear to have been a significant increase in suicides since the pandemic began in the countries for which we had data. In fact, in a number of countries/areas-within-countries there appears to have been a decrease.InterpretationThis is the first study to examine suicides occurring in the context of the COVID-19 pandemic in multiple countries. It offers a consistent picture, albeit from high- and upper-middle income countries, of suicide numbers largely remaining unchanged or declining in the early months of the pandemic. We need to remain vigilant and be poised to respond if the situation changes as the longer-term mental health and economic impacts of the pandemic unfold

Scope

Scope, later retitled Centerscope, was published by the Boston University Medical Center to report on events at and around the Center

Methoden zur Stoerschallunterdrueckung bei ortsungebundener Spracheingabe in Raeumen

SIGLEAvailable from TIB Hannover: DW 5091 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Current approaches and utilization of new screening techniques for evaluation of FHB resistance at CIMMYT.

Fusarium head blight (FHB) is a major disease of wheat in most wheat growing areas of the world. Resis- tance to FHB is a key trait for CIMMYT and many wheat breeding programs worldwide. New plant pheno- typing techniques such as quantification of fungal biomass using real-time PCR have become available re- cently. CIMMYT’s approach is to test new techniques for their feasibility and to apply them in routine disease screening programs if they prove to be valuable. Two sets of spring wheat genotypes assembled on the basis of low (group 1) and high (group 2) FHB index observed in previous years, were phenotyped and genotyped in CIMMYT’s FHB screening program. Phenotyping consisted of visual disease scoring (FHB index), mycotoxin analysis (DON) and quantification of fungal biomass. Apart from the FHB index, the two groups differed slightly in terms of DON accumulation although no differences were observed for average fungal biomass. This observation combined with the lack of correlation between disease symptoms and amount of fungal biomass suggested that some useful informa- tion may not be considered to discriminate resistant from susceptible genotypes when field selection is solely based on visual scoring results. DON/biomass-ratio was assessed for all genotypes and was found to be higher in the more resistant group 1 contrary to expectiations. An increase in DON production resulting from a stress or from resistance is discussed as a possible hypothesis. The determination of fungal biomass proved to be potentially valuable as a phenotyping tool. Genotyping results also showed that new genotypes harboring moderate levels of resistance and differing from traditional sources of scab resistance become available