77 research outputs found

    Effects of Irrigation Frequency and Manure on Growth Parameters, Crop Coefficient and Yield of Okro (Abelmoscus Esculeutus)

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    It is essential to maintain readily available water in the soil if crops are to make satisfactory growth and give optimum yield. This work studied the response of Okro to the application of different regimes of irrigation water (W1, W2 and W3) in order to determine its growth performance and yield. Twenty seven (27) bucket of the volumetric capacity of 10litres each, Okro was planted in each bucket equal treatment of animal and organic fertilizer was applied in the ratio 6:1 while response to plant height observed were 13 cm, 10.8 cm and 15 cm, also, stem diameter observed were 0.06 mm, 0.12 mm, and 0.17 mm.The effects of irrigation frequency, average plant height (cm), average number of leaves; average Stem (diameter, mm) and yield (g) were studied.  W1 gave 13, 4, 0.06, 11.4; W2:  10.8, 6, 0.12, 18.1; W3: 15, 7, 0.17, 23.3. Plants under W3 recorded the highest plant height and it also produced the highest number of leaves at 7 stem diameter (0.17mm) and consequently the highest mean yield. The study showed that with readily available nutrients present in soil, the most desirable frequency of irrigation gives an optimum crop yield as nutrients is easily taken up by plants. It is recommended that a standard model green house be constructed to study various crop coefficients and consumptive use for this zone. Keywords: irrigation frequency, growth parameters, crop coefficient, yield, Okr

    Growth of Pseudomonas fluorescens on Cassava Starch hydrolysate for Polyhydroxybutyrate production

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    The potential of local strains of microorganism (Pseudomonas fluorescens) in polyhydroxbutyrate production was investigated in this study. This was with a view to establishing the capabilities of local strains of microorganisms on utilizing renewable and locally available substrates in polyhydroxybutyrate production. This involved hydrolysis of starch extracted from freshly harvested cassava tubers using enzyme-enzyme method of hydrolysis, followed by aerobic fermentation of Pseudomonas fluorescens on a mixture of the hydrolysate and nutrient media in a fermentor in batch cultures. The reducing sugar hydrolysate served as the carbon source and diammonium sulphate as the limiting nutrient. The reaction temperature, pH and agitation rate in the fermentor were maintained at 30°C, 7.5 and 400 rpm respectively. The biomass growth was measured by cell dry weight and the polyhydroxybutyrate content measured by gas chromatography. When the fermentation process was shut down after 84 hour, the substrate consumption by the organism was 9.2 g/L to give a dry cell weight of 1.75 g/L resulting in a biomass yield on substrate (Yx/s) of 0.1902 g/g (19.02 % wt/wt). The gas chromatographic analysis gave a final polyhydroxybutyrate value of 1.254 g/L with corresponding product yield on biomass (Yp/x) of 0.7166 g g-1 [71.66% wt/wt] and product yield on substrate (Yp/s) of 0.1363 g g-1 [13.63% wt/wt]. The results show that the organism accumulated polyhydroxybutyrate in excess of 50 % of the cell dry weight by giving a final polyhydroxybutyrate yield on biomass (Yp/x) of 0.7166 g g-1 [71.66% wt/wt] which agrees with the general trend in polyhydroxybutyrate production. @ JASEMJ. Appl. Sci. Environ. Manage. December, 2010, Vol. 14 (4) 61 - 6

    SCHOOL EAR,NOSEAND THROAT DISEASES SCREENING PROGRAMME IN LAGOS,NIGERIA

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    Background: Ear, nose and throat disease remain a common diseases in children in developing countries. It is usually wrongly or late diagnosed or complicated at presentation to Otorhinolaryngologist. is study aimed at determines the common ear, nose and throat diseases and their prevalence in children at studied age group with possible responsible factor. Materials and method: It is a prospective study of pupils in a private nursery (preschool) and primary school in urban area of Lagos, Nigeria. Inform consent was obtained from parent or guardian through the parent-teachers association of the school. A total of 512 consented subjects were enrolled into the study between March 2015 and February 2016. Data obtained were collated and statistically analyzed using SPSS version 16. Results: A total of 512 pupils were enrolled into the study with male: female ratio 1:1. Commonest age group were 0-5 years. Normal otorhinolaryngological findings was noted in minority population 71 (13.9%) of our enrollee. Ear, nose and throat diseases accounted for 54.1%, 55.3% and 18.0% respectively. Earwax impaction 23.0% accounted for the commonest ear pathology. Other common ear diseases were otitis media with effusion, hearing loss and otitis externa were 15.0%, 8.3% and 5.1% respectively. Nasal diseases were found to be 26.2%, allergic rhinitis 12.1%, infective rhinitis and 9.4% adenoid enlargement. Distribution of throat diseases were 9.0% tonsillitis and 5.5%speech disorders. About 98.0% had past history of ear, nose or throat diseases treated by 60.9% family physician, 20.1% paediatrician and 87 (17.0%) of the participants has had otorhinolaryngological consultation in life and 16 (3.1%) had either major or minor ear, nose and throat surgery before. ere is scarcity of ear, nose and throat care centre and otolaryngologist and their services. Conclusion: Preventable ear, nose and throat diseases were common among school children. Routine annual school otorhinolaryngological screening is recomended for preschool and school children

    Malignant Otitis Externa in Developing Country

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    Objective: Malignant otitis externa is a potentially life threatening infection of external auditory canal and skull base in an immunocompromised person. The outcome tends to be fatal due to the skull base osteomyelitis, especially if diagnois is delayed or is poorly treated. This epidemiological study in developing country is aimed at sensitizing for high level of suspicious early diagnosis and treatment. Method: This is a prospective study of patients with diagnosis of malignant otitis externa managed in a tertiary hospital between year 2012 - 2016. All consented patients with the disorder were enrolled into the study. Data obtained were collated and analysed. Result: Nine patients with malignant otitis externa were seen during the study period. Male to female ratio was 1:1. The peak was between 61 and 70 years. The most frequent symptoms were otalgia 9 (100%) and hearing loss 9 (100%) while cranial neuropathy was encountered in 6 (66.7%). The most implicated microganisms was Pseudomonas aeruginosa 7(28%). All patients had combination of both medical and surgical intervention. There was 1death (11.1%). Conclusion: Malignant otitis external is a complication of diabetes with high morbidity, however prompt diagnosis and treatment could mitigate the mortalit

    Ear, nose and throat injuries at Bugando Medical Centre in northwestern Tanzania: a five-year prospective review of 456 cases.

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    Injuries to the ear, nose and throat (ENT) regions are not uncommon in clinical practice and constitute a significant cause of morbidity and mortality in our setting. There is dearth of literature on this subject in our environment. This study was conducted to describe the causes, injury pattern and outcome of these injuries in our setting and proffer possible preventive measures. This was a descriptive prospective study of patients with ear, nose and throat injuries managed at Bugando Medical Centre between May 2007 and April 2012. Ethical approval to conduct the study was sought from relevant authorities. Statistical data analysis was performed using SPSS computer software version 17.0. A total of 456 patients were studied. The median age of patients at presentation was 18 years (range 1 to 72 years). The male to female ratio was 2:1. The commonest cause of injury was foreign bodies (61.8%) followed by road traffic accidents (22.4%). The ear was the most common body region injured accounting for 59.0% of cases. The majority of patients (324, 71.1%) were treated as an outpatient and only 132(28.9%) patients required admission to the ENT wards after definitive treatment. Foreign body removal and surgical wound debridement were the most common treatment modalities performed in 61.9% and 16.2% of cases respectively. Complication rate was 14.9%. Suppurative otitis media (30.9%) was the commonest complication in the ear while traumatic epistaxis (26.5%) and hoarseness of voice (11.8%) in the aero-digestive tract were commonest in the nose and throat. The overall median length of hospital stay for in-patients was 8 days (range 1 to 22 days). Patients who developed complications and those who had associated injuries stayed longer in the hospital (P < 0.001).Mortality rate related to isolated ENT injuries was 1.3% (6 deaths). The majority of patients (96.9%) were treated successfully and only 3.1% of cases were discharged with permanent disabilities. Injuries to the ENT regions are not uncommon in our environment and foreign bodies constitute a significant cause of injury. Majority of these injuries can be prevented through public enlightenment campaigns

    Foreign Bodies in the Upper Aerodigestive Tract of Nigerian Children

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    Aim/Background This is an audit of number, nature, sites of impaction and methods of removals and treatment outcome of upper aero-digestive foreign bodies among children in an urban University hospital in Nigeria. Patients and Methods This is an 8year retrospective review of foreign body in upper aero-dgestive tract of children (January 2001 to December 2007) was conducted at the ENT department of the University of Ilorin Teaching Hospital, Ilorin, Nigeria . Case notes of the patients were retrieved and the following were data extracted: demographic, clinical, operative and outpatient visits outcome. Results 81 children aged 9months to 16years were seen (mean 4.28, SD 2.95) with 49 males and 32 females and a male: female ratio of 1.5: 1.0.The commonest age group was 9months to 4years (76.5%). Most common of impaction sites were nasal cavity in 31 cases (38.3%), oesophagus in 23 cases (28.4%), oropharynx in 16 (19.8%) and larynx in 6 (7.4%)).The commonest FBs was coins in 33 (40.7 %) in the oesophagus and 37.5% of pharyngeal FBs .Inanimate FBs in the nose constituted 31(38.3%) [Non vegetative 27(87.1%), vegetative 4(12.9 %)]. Fish bones were seen in 11 cases (13.6%) [6 in the larynx and 5 around the tonsillar fauces] and miscellaneous objects in 6 cases. Conclusion Upper aero-digestive foreign bodies are common especially among the under fours', commonest sites being the nose and pharyngooesophageal region with coins and inanimate FBs constituting about four-fifth. There is the need for parental health education on object placements, and a high index of suspicion among practitioners to facilitate early referral and avoid preventable complications

    Past, present, and future of global health financing : a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995-2050

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    Background Comprehensive and comparable estimates of health spending in each country are a key input for health policy and planning, and are necessary to support the achievement of national and international health goals. Previous studies have tracked past and projected future health spending until 2040 and shown that, with economic development, countries tend to spend more on health per capita, with a decreasing share of spending from development assistance and out-of-pocket sources. We aimed to characterise the past, present, and predicted future of global health spending, with an emphasis on equity in spending across countries. Methods We estimated domestic health spending for 195 countries and territories from 1995 to 2016, split into three categories-government, out-of-pocket, and prepaid private health spending-and estimated development assistance for health (DAH) from 1990 to 2018. We estimated future scenarios of health spending using an ensemble of linear mixed-effects models with time series specifications to project domestic health spending from 2017 through 2050 and DAH from 2019 through 2050. Data were extracted from a broad set of sources tracking health spending and revenue, and were standardised and converted to inflation-adjusted 2018 US dollars. Incomplete or low-quality data were modelled and uncertainty was estimated, leading to a complete data series of total, government, prepaid private, and out-of-pocket health spending, and DAH. Estimates are reported in 2018 US dollars, 2018 purchasing-power parity-adjusted dollars, and as a percentage of gross domestic product. We used demographic decomposition methods to assess a set of factors associated with changes in government health spending between 1995 and 2016 and to examine evidence to support the theory of the health financing transition. We projected two alternative future scenarios based on higher government health spending to assess the potential ability of governments to generate more resources for health. Findings Between 1995 and 2016, health spending grew at a rate of 4.00% (95% uncertainty interval 3.89-4.12) annually, although it grew slower in per capita terms (2.72% [2.61-2.84]) and increased by less than 1percapitaoverthisperiodin22of195countries.Thehighestannualgrowthratesinpercapitahealthspendingwereobservedinupper−middle−incomecountries(5.55 1 per capita over this period in 22 of 195 countries. The highest annual growth rates in per capita health spending were observed in upper-middle-income countries (5.55% [5.18-5.95]), mainly due to growth in government health spending, and in lower-middle-income countries (3.71% [3.10-4.34]), mainly from DAH. Health spending globally reached 8.0 trillion (7.8-8.1) in 2016 (comprising 8.6% [8.4-8.7] of the global economy and 10.3trillion[10.1−10.6]inpurchasing−powerparity−adjusteddollars),withapercapitaspendingofUS 10.3 trillion [10.1-10.6] in purchasing-power parity-adjusted dollars), with a per capita spending of US 5252 (5184-5319) in high-income countries, 491(461−524)inupper−middle−incomecountries, 491 (461-524) in upper-middle-income countries, 81 (74-89) in lower-middle-income countries, and 40(38−43)inlow−incomecountries.In2016,0.4 40 (38-43) in low-income countries. In 2016, 0.4% (0.3-0.4) of health spending globally was in low-income countries, despite these countries comprising 10.0% of the global population. In 2018, the largest proportion of DAH targeted HIV/AIDS ( 9.5 billion, 24.3% of total DAH), although spending on other infectious diseases (excluding tuberculosis and malaria) grew fastest from 2010 to 2018 (6.27% per year). The leading sources of DAH were the USA and private philanthropy (excluding corporate donations and the Bill & Melinda Gates Foundation). For the first time, we included estimates of China's contribution to DAH (644.7millionin2018).Globally,healthspendingisprojectedtoincreaseto 644.7 million in 2018). Globally, health spending is projected to increase to 15.0 trillion (14.0-16.0) by 2050 (reaching 9.4% [7.6-11.3] of the global economy and $ 21.3 trillion [19.8-23.1] in purchasing-power parity-adjusted dollars), but at a lower growth rate of 1.84% (1.68-2.02) annually, and with continuing disparities in spending between countries. In 2050, we estimate that 0.6% (0.6-0.7) of health spending will occur in currently low-income countries, despite these countries comprising an estimated 15.7% of the global population by 2050. The ratio between per capita health spending in high-income and low-income countries was 130.2 (122.9-136.9) in 2016 and is projected to remain at similar levels in 2050 (125.9 [113.7-138.1]). The decomposition analysis identified governments' increased prioritisation of the health sector and economic development as the strongest factors associated with increases in government health spending globally. Future government health spending scenarios suggest that, with greater prioritisation of the health sector and increased government spending, health spending per capita could more than double, with greater impacts in countries that currently have the lowest levels of government health spending. Interpretation Financing for global health has increased steadily over the past two decades and is projected to continue increasing in the future, although at a slower pace of growth and with persistent disparities in per-capita health spending between countries. Out-of-pocket spending is projected to remain substantial outside of high-income countries. Many low-income countries are expected to remain dependent on development assistance, although with greater government spending, larger investments in health are feasible. In the absence of sustained new investments in health, increasing efficiency in health spending is essential to meet global health targets.Peer reviewe

    Past, present, and future of global health financing: a review of development assistance, government, out-of-pocket, and other private spending on health for 195 countries, 1995–2050

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    Background: Comprehensive and comparable estimates of health spending in each country are a key input for health policy and planning, and are necessary to support the achievement of national and international health goals. Previous studies have tracked past and projected future health spending until 2040 and shown that, with economic development, countries tend to spend more on health per capita, with a decreasing share of spending from development assistance and out-of-pocket sources. We aimed to characterise the past, present, and predicted future of global health spending, with an emphasis on equity in spending across countries. Methods: We estimated domestic health spending for 195 countries and territories from 1995 to 2016, split into three categories—government, out-of-pocket, and prepaid private health spending—and estimated development assistance for health (DAH) from 1990 to 2018. We estimated future scenarios of health spending using an ensemble of linear mixed-effects models with time series specifications to project domestic health spending from 2017 through 2050 and DAH from 2019 through 2050. Data were extracted from a broad set of sources tracking health spending and revenue, and were standardised and converted to inflation-adjusted 2018 US dollars. Incomplete or low-quality data were modelled and uncertainty was estimated, leading to a complete data series of total, government, prepaid private, and out-of-pocket health spending, and DAH. Estimates are reported in 2018 US dollars, 2018 purchasing-power parity-adjusted dollars, and as a percentage of gross domestic product. We used demographic decomposition methods to assess a set of factors associated with changes in government health spending between 1995 and 2016 and to examine evidence to support the theory of the health financing transition. We projected two alternative future scenarios based on higher government health spending to assess the potential ability of governments to generate more resources for health. Findings: Between 1995 and 2016, health spending grew at a rate of 4·00% (95% uncertainty interval 3·89–4·12) annually, although it grew slower in per capita terms (2·72% [2·61–2·84]) and increased by less than 1percapitaoverthisperiodin22of195countries.Thehighestannualgrowthratesinpercapitahealthspendingwereobservedinupper−middle−incomecountries(5⋅55inlower−middle−incomecountries(3⋅711 per capita over this period in 22 of 195 countries. The highest annual growth rates in per capita health spending were observed in upper-middle-income countries (5·55% [5·18–5·95]), mainly due to growth in government health spending, and in lower-middle-income countries (3·71% [3·10–4·34]), mainly from DAH. Health spending globally reached 8·0 trillion (7·8–8·1) in 2016 (comprising 8·6% [8·4–8·7] of the global economy and 10⋅3trillion[10⋅1–10⋅6]inpurchasing−powerparity−adjusteddollars),withapercapitaspendingofUS10·3 trillion [10·1–10·6] in purchasing-power parity-adjusted dollars), with a per capita spending of US5252 (5184–5319) in high-income countries, 491(461–524)inupper−middle−incomecountries,491 (461–524) in upper-middle-income countries, 81 (74–89) in lower-middle-income countries, and 40(38–43)inlow−incomecountries.In2016,0⋅4countries,despitethesecountriescomprising10⋅0DAHtargetedHIV/AIDS(40 (38–43) in low-income countries. In 2016, 0·4% (0·3–0·4) of health spending globally was in low-income countries, despite these countries comprising 10·0% of the global population. In 2018, the largest proportion of DAH targeted HIV/AIDS (9·5 billion, 24·3% of total DAH), although spending on other infectious diseases (excluding tuberculosis and malaria) grew fastest from 2010 to 2018 (6·27% per year). The leading sources of DAH were the USA and private philanthropy (excluding corporate donations and the Bill & Melinda Gates Foundation). For the first time, we included estimates of China’s contribution to DAH (644⋅7millionin2018).Globally,healthspendingisprojectedtoincreaseto644·7 million in 2018). Globally, health spending is projected to increase to 15·0 trillion (14·0–16·0) by 2050 (reaching 9·4% [7·6–11·3] of the global economy and $21·3 trillion [19·8–23·1] in purchasing-power parity-adjusted dollars), but at a lower growth rate of 1·84% (1·68–2·02) annually, and with continuing disparities in spending between countries. In 2050, we estimate that 0·6% (0·6–0·7) of health spending will occur in currently low-income countries, despite these countries comprising an estimated 15·7% of the global population by 2050. The ratio between per capita health spending in high-income and low-income countries was 130·2 (122·9–136·9) in 2016 and is projected to remain at similar levels in 2050 (125·9 [113·7–138·1]). The decomposition analysis identified governments’ increased prioritisation of the health sector and economic development as the strongest factors associated with increases in government health spending globally. Future government health spending scenarios suggest that, with greater prioritisation of the health sector and increased government spending, health spending per capita could more than double, with greater impacts in countries that currently have the lowest levels of government health spending Interpretation: Financing for global health has increased steadily over the past two decades and is projected to continue increasing in the future, although at a slower pace of growth and with persistent disparities in per-capita health spending between countries. Out-of-pocket spending is projected to remain substantial outside of high-income countries. Many low-income countries are expected to remain dependent on development assistance, although with greater government spending, larger investments in health are feasible. In the absence of sustained new investments in health, increasing efficiency in health spending is essential to meet global health targets. Funding: Bill & Melinda Gates Foundatio

    Global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2017, and forecasts to 2030, for 195 countries and territories: a systematic analysis for the Global Burden of Diseases, Injuries, and Risk Factors Study 2017

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    Background Understanding the patterns of HIV/AIDS epidemics is crucial to tracking and monitoring the progress of prevention and control efforts in countries. We provide a comprehensive assessment of the levels and trends of HIV/AIDS incidence, prevalence, mortality, and coverage of antiretroviral therapy (ART) for 1980–2017 and forecast these estimates to 2030 for 195 countries and territories. Methods We determined a modelling strategy for each country on the basis of the availability and quality of data. For countries and territories with data from population-based seroprevalence surveys or antenatal care clinics, we estimated prevalence and incidence using an open-source version of the Estimation and Projection Package—a natural history model originally developed by the UNAIDS Reference Group on Estimates, Modelling, and Projections. For countries with cause-specific vital registration data, we corrected data for garbage coding (ie, deaths coded to an intermediate, immediate, or poorly defined cause) and HIV misclassification. We developed a process of cohort incidence bias adjustment to use information on survival and deaths recorded in vital registration to back-calculate HIV incidence. For countries without any representative data on HIV, we produced incidence estimates by pulling information from observed bias in the geographical region. We used a re-coded version of the Spectrum model (a cohort component model that uses rates of disease progression and HIV mortality on and off ART) to produce age-sex-specific incidence, prevalence, and mortality, and treatment coverage results for all countries, and forecast these measures to 2030 using Spectrum with inputs that were extended on the basis of past trends in treatment scale-up and new infections. Findings Global HIV mortality peaked in 2006 with 1·95 million deaths (95% uncertainty interval 1·87–2·04) and has since decreased to 0·95 million deaths (0·91–1·01) in 2017. New cases of HIV globally peaked in 1999 (3·16 million, 2·79–3·67) and since then have gradually decreased to 1·94 million (1·63–2·29) in 2017. These trends, along with ART scale-up, have globally resulted in increased prevalence, with 36·8 million (34·8–39·2) people living with HIV in 2017. Prevalence of HIV was highest in southern sub-Saharan Africa in 2017, and countries in the region had ART coverage ranging from 65·7% in Lesotho to 85·7% in eSwatini. Our forecasts showed that 54 countries will meet the UNAIDS target of 81% ART coverage by 2020 and 12 countries are on track to meet 90% ART coverage by 2030. Forecasted results estimate that few countries will meet the UNAIDS 2020 and 2030 mortality and incidence targets. Interpretation Despite progress in reducing HIV-related mortality over the past decade, slow decreases in incidence, combined with the current context of stagnated funding for related interventions, mean that many countries are not on track to reach the 2020 and 2030 global targets for reduction in incidence and mortality. With a growing population of people living with HIV, it will continue to be a major threat to public health for years to come. The pace of progress needs to be hastened by continuing to expand access to ART and increasing investments in proven HIV prevention initiatives that can be scaled up to have population-level impact
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