Ischemia/Reperfusion Injury of the Ascending Colon in Ponies: A Correlative Study Utilizing Microvascular Histopathology and Corrosion Casting

Volvulus of the ascending colon (ACV) in the horse results in microvascular injury and necrosis of the intestinal mucosa. This study investigated the site and type of microvascular injury which occurs within the mucosa and sub mucosa following ACV. Histopathology of volvulus treated ponies demonstrated mucosa! necrosis with microvascular hemorrhage and thrombosis. Thrombi occurred within the subepithelial capillaries and edema and hemorrhage developed throughout the mucosa and submucosa. Vascular casts allowed 3-D viewing of samples obtained from the entire pelvic flexure and demonstrated two distinct microvascular changes: 1) disruption of the colonic glandular capillary network occurred concomitantly with the mucosal injury, and 2) extensive endothelial leakage from the submucosal microvasculature contributes to edema formation. Thus, microcorrosion casting of the equine pelvic flexure provided an effective means to characterize the location and severity of vascular leakage and visualize the extent and severity of injury to the capillary network not easily depicted by histopathology. Microvascular casting in conjunction with routine histopathology provided additional information on the pathomorphologic changes in this model of ischemia/reperfusion injury

The ATLAS magnet test facility at CERN

The magnet system for the ATLAS detector at CERN consists of a Barrel Toroid (BT), two End-Cap Toroids (ECT) and a Central Solenoid (CS). The overall dimensions of the system are 20 m in diameter by 26 m in length. Before underground installation all coils will be tested on surface in a magnet test facility which is under construction. Moreover two model coils are tested as well as subsystems. In this paper the design and construction of the test facility is presented. (3 refs)

Performance of the ATLAS electromagnetic calorimeter end-cap module 0

The construction and beam test results of the ATLAS electromagnetic end-cap calorimeter pre-production module 0 are presented. The stochastic term of the energy resolution is between 10% GeV^1/2 and 12.5% GeV^1/2 over the full pseudorapidity range. Position and angular resolutions are found to be in agreement with simulation. A global constant term of 0.6% is obtained in the pseudorapidity range 2.5 eta 3.2 (inner wheel)

Performance of the ATLAS Electromagnetic Calorimeter End-cap Module 0

The construction and beam test results of the ATLAS electromagnetic end-cap calorimeter pre-production module 0 are presented. The stochastic term of the energy resolution is between 10% GeV^1/2 and 12.5% GeV^1/2 over the full pseudorapidity range. Position and angular resolutions are found to be in agreement with simulation. A global constant term of 0.6% is obtained in the pseudorapidity range 2.5 < eta < 3.2 (inner wheel)

Readout technologies for directional WIMP Dark Matter detection

The measurement of the direction of WIMP-induced nuclear recoils is a compelling but technologically challenging strategy to provide an unambiguous signature of the detection of Galactic dark matter. Most directional detectors aim to reconstruct the dark-matter-induced nuclear recoil tracks, either in gas or solid targets. The main challenge with directional detection is the need for high spatial resolution over large volumes, which puts strong requirements on the readout technologies. In this paper we review the various detector readout technologies used by directional detectors. In particular, we summarize the challenges, advantages and drawbacks of each approach, and discuss future prospects for these technologies

Performance of a lead-glass detector for high-energy gamma -rays

An array of 84 lead-glass blocks covering 1.8 m/sup 2/ has been used in a series of experiments in a short-lived neutral beam at the CERN PS. The photon energy is measured with a fwhm of Delta E=0.11* square root E(GeV) for photon energies between 0.5 and 5.0 GeV. The energy calibration has been monitored continuously during the course of the experiments using electrons which originated mainly from K/sub e3//sup 0/ decays, the momenta being measured in a magnetic spectrometer. (14 refs)