331 research outputs found

    The renormalization of the axial anomaly in dimensional regularization

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    The prescription for the Îł5\gamma_5-matrix within dimensional regularization in multiloop calculations is elaborated. The three-loop anomalous dimension of the singlet axial current is calculated.Comment: 11 pages, 1 figure available on request from the author, NIKHEF-H/92-1

    Four-loop beta function and mass anomalous dimension in Dimensional Reduction

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    Within the framework of QCD we compute renormalization constants for the strong coupling and the quark masses to four-loop order. We apply the DR-bar scheme and put special emphasis on the additional couplings which have to be taken into account. This concerns the epsilon-scalar--quark Yukawa coupling as well as the vertex containing four epsilon-scalars. For a supersymmetric Yang Mills theory, we find, in contrast to a previous claim, that the evanescent Yukawa coupling equals the strong coupling constant through three loops as required by supersymmetry.Comment: 15 pages, fixed typo in Eq. (18

    Holomorphic potentials for graded D-branes

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    We discuss gauge-fixing, propagators and effective potentials for topological A-brane composites in Calabi-Yau compactifications. This allows for the construction of a holomorphic potential describing the low-energy dynamics of such systems, which generalizes the superpotentials known from the ungraded case. Upon using results of homotopy algebra, we show that the string field and low energy descriptions of the moduli space agree, and that the deformations of such backgrounds are described by a certain extended version of `off-shell Massey products' associated with flat graded superbundles. As examples, we consider a class of graded D-brane pairs of unit relative grade. Upon computing the holomorphic potential, we study their moduli space of composites. In particular, we give a general proof that such pairs can form acyclic condensates, and, for a particular case, show that another branch of their moduli space describes condensation of a two-form.Comment: 47 pages, 7 figure

    Birth defects associated with paternal firefighting in the National Birth Defects Prevention Study

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    Background: Few studies have evaluated birth defects among children of firefighters. We investigated associations between birth defects and paternal work as a firefighter compared to work in non-firefighting and police officer occupations. Methods: We analyzed 1997–2011 data from the multi-site case-control National Birth Defects Prevention Study. Cases included fetuses or infants with major structural birth defects and controls included a random sample of live-born infants without major birth defects. Mothers of infants self-reported information about parents' occupations held during pregnancy. We investigated associations between paternal firefighting and birth defect groups using logistic regression to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Referent groups included families reporting fathers working non-firefighting and police officer jobs. Results: Occupational groups included 227 firefighters, 36,285 non-firefighters, and 433 police officers. Twenty-nine birth defects were analyzed. In adjusted analyses, fathers of children with total anomalous pulmonary venous return (TAPVR; OR = 3.1; 95% CI = 1.1–8.7), cleft palate (OR = 1.8; 95% CI = 1.0–3.3), cleft lip (OR = 2.2; 95% CI = 1.2–4.2), and transverse limb deficiency (OR = 2.2; 95% CI = 1.1–4.7) were more likely than fathers of controls to be firefighters, versus non-firefighters. In police-referent analyses, fathers of children with cleft palate were 2.4 times more likely to be firefighters than fathers of controls (95% CI = 1.1–5.4). Conclusions: Paternal firefighting may be associated with an elevated risk of birth defects in offspring. Additional studies are warranted to replicate these findings. Further research may contribute to a greater understanding of the reproductive health of firefighters and their families for guiding workplace practices

    Vacuum instability in external fields

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    We study particles creation in arbitrary space-time dimensions by external electric fields, in particular, by fields, which are acting for a finite time. The time and dimensional analysis of the vacuum instability is presented. It is shown that the distributions of particles created by quasiconstant electric fields can be written in a form which has a thermal character and seems to be universal. Its application, for example, to the particles creation in external constant gravitational field reproduces the Hawking temperature exactly.Comment: 36 pages, LaTe

    Supersymmetric Regularization, Two-Loop QCD Amplitudes and Coupling Shifts

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    We present a definition of the four-dimensional helicity (FDH) regularization scheme valid for two or more loops. This scheme was previously defined and utilized at one loop. It amounts to a variation on the standard 't Hooft-Veltman scheme and is designed to be compatible with the use of helicity states for "observed" particles. It is similar to dimensional reduction in that it maintains an equal number of bosonic and fermionic states, as required for preserving supersymmetry. Supersymmetry Ward identities relate different helicity amplitudes in supersymmetric theories. As a check that the FDH scheme preserves supersymmetry, at least through two loops, we explicitly verify a number of these identities for gluon-gluon scattering (gg to gg) in supersymmetric QCD. These results also cross-check recent non-trivial two-loop calculations in ordinary QCD. Finally, we compute the two-loop shift between the FDH coupling and the standard MS-bar coupling, alpha_s. The FDH shift is identical to the one for dimensional reduction. The two-loop coupling shifts are then used to obtain the three-loop QCD beta function in the FDH and dimensional reduction schemes.Comment: 44 pages, minor corrections and clarifications include

    The state of the Martian climate

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    60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

    Neurologic Phenotypes Associated With Mutations in RTN4IP1 (OPA10) in Children and Young Adults

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    Importance: Neurologic disorders with isolated symptoms or complex syndromes are relatively frequent among mitochondrial inherited diseases. Recessive RTN4IP1 gene mutations have been shown to cause isolated and syndromic optic neuropathies. Objective: To define the spectrum of clinical phenotypes associated with mutations in RTN4IP1 encoding a mitochondrial quinone oxidoreductase. Design, Setting, and Participants: This study involved 12 individuals from 11 families with severe central nervous system diseases and optic atrophy. Targeted and whole-exome sequencing were performed-at Hospital Angers (France), Institute of Neurology Milan (Italy), Imagine Institute Paris (France), Helmoltz Zentrum of Munich (Germany), and Beijing Genomics Institute (China)-to clarify the molecular diagnosis of patients. Each patient\u27s neurologic, ophthalmologic, magnetic resonance imaging, and biochemical features were investigated. This study was conducted from May 1, 2014, to June 30, 2016. Main Outcomes and Measures: Recessive mutations in RTN4IP1 were identified. Clinical presentations ranged from isolated optic atrophy to severe encephalopathies. Results: Of the 12 individuals in the study, 6 (50%) were male and 6 (50%) were female. They ranged in age from 5 months to 32 years. Of the 11 families, 6 (5 of whom were consanguineous) had a member or members who presented isolated optic atrophy with the already reported p.Arg103His or the novel p.Ile362Phe, p.Met43Ile, and p.Tyr51Cys amino acid changes. The 5 other families had a member or members who presented severe neurologic syndromes with a common core of symptoms, including optic atrophy, seizure, intellectual disability, growth retardation, and elevated lactate levels. Additional clinical features of those affected were deafness, abnormalities on magnetic resonance images of the brain, stridor, and abnormal electroencephalographic patterns, all of which eventually led to death before age 3 years. In these patients, novel and very rare homozygous and compound heterozygous mutations were identified that led to the absence of the protein and complex I disassembly as well as mild mitochondrial network fragmentation. Conclusions and Relevance: A broad clinical spectrum of neurologic features, ranging from isolated optic atrophy to severe early-onset encephalopathies, is associated with RTN4IP1 biallelic mutations and should prompt RTN4IP1 screening in both syndromic neurologic presentations and nonsyndromic recessive optic neuropathies
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