Non-heme iron hydroperoxo species in superoxide reductase as a catalyst for oxidation reactions

International audienceThe non-hemehigh-spin ferric iron hydroperoxo species formed in superoxide reductase catalyzesoxidative aldehyde deformylation through its nucleophile character.This species also acts as an electrophile to catalyze oxygen atom transfer in sulfoxidation reactions, highlighting the oxidation potential of non-heme iron hydroperoxo species. The mechanisms of oxygen activation and oxidation reactions catalyzed by metalloenzymes have been thoroughly investigated during the last past decades. 1-5 For cytochrome P450 5, 6 and several non-heme iron monooxygenases, 4, 7, 8 it is now well admitted that high-valent iron-oxo species formed at their active site is the effective oxidant for organic substrate oxidation and oxygen transfer. Nevertheless, the fact that alternative species, e.g. ferric iron (hydro)peroxide intermediate, 1 or other metal-oxidant adducts, 9

Introduction to the French GEOTRACES North Atlantic Transect (GA01): GEOVIDE cruise

The GEOVIDE cruise, a collaborative project within the framework of the international GEOTRACES programme, was conducted along the French-led section in the North Atlantic Ocean (Section GA01), between 15 May and 30 June 2014. In this special issue (https://www.biogeosciences.net/special_issue900.html), results from GEOVIDE, including physical oceanography and trace element and isotope cyclings, are presented among 18 articles. Here, the scientific context, project objectives, and scientific strategy of GEOVIDE are provided, along with an overview of the main results from the articles published in the special issue

Spirituality and childbirth: An international virtual co-operative inquiry

PROBLEM: Medicalised maternity systems do not address spirituality as an aspect of childbirth and its practices of care. Neglecting the spiritual nature of childbirth may negatively affect psychological, emotional and physical wellbeing. BACKGROUND: While there is growing interest in the spiritual side of childbirth there is a paucity of literature on the topic, and hence a lack of understanding generally about how to attend to women's needs for emotional and spiritual support in childbirth. AIM: To collaboratively and through consensus explore ways that spirituality could be honoured in 2st Century maternity care. METHODS: An online co-operative inquiry. Starting with a scoping exercise (N=17) nine co-inquirers continued to Phase One using online discussion boards and seven co-inquirers continued to Phase Two and Three. Co-inquirers were involved in international group work and individual reflective and transformational processes throughout. FINDINGS: Four reflective themes emerged: 'meaning and sense-making'; 'birth culture'; 'embodied relationships and intuition'; and 'space/place/time'. 'Spiritual midwifing' was an overarching theme. There were eight areas of individual transformation and actions concerning spirituality and birth: 1) disseminating inquiry findings; 2) motivating conversations and new ways of thinking; 3) remembering interconnectedness across time and spaces; 4) transforming relationships; 5) transforming practice; 6) generating reflexivity; 7) inspiring self and others to change, and 8) inspiring creativity. CONCLUSION: Spiritual awareness around birth experience emerges through relationships and is affected by the spatial environment. Spiritual midwifing is a relational approach to birth care that recognises and honours the existential significance and meaningfulness of childbirth

Implantable SAW sensor for telemetry of temperature and blood pressure: The ANR-TECSAN CIMPA project

NUMÉRO SPÉCIAL ANRInternational audienceThe CIMPA Project (2007-2008), led under the ANR-TECSAN Call, was coordinated by SENSeOR, in partnership with the LEAT and the FEMTO. The aim of the project was to develop a surface acoustic wave sensor demonstrator, passive implantable to monitoring the blood pressure and the temperature. This sensor uses the surface acoustic wave technology (SAW) and is composed of three resonators using quartz as piezoelectric substrate. One resonator for temperature measurement (T), a second resonator for the blood pressure measurement (P) and a third resonator, which is used as reference (R). This sensor is compatible with size requirements inherent to an implantation in an artery, since the size of the resonator with its antennas in its most compact configuration is of the order of 5.2mm×3.7mm×0.85mm. It requires no embarked sources of energy and being able to be interrogated by a radiofréquence (RF) connection thanks to a transceiver, which emits a signal in the band industrial, scientific and medical (ISM). The sensor (connected to an integrated antenna on quartz of very small dimension) requested by the signal of interrogation emits in its turn a signal, which carries information of pressure and temperature. The transceiver then collects apart from its transmitting phase the signal emitted by the sensor and extracts by an appropriate signal processing method information of pressure and temperature. The targeted range for pressure measurement extends from 1bar to 1.35bar with an accuracy of about 2% FS

The Value of Molecular vs. Morphometric and Acoustic Information for Species Identification Using Sympatric Molossid Bats

A fundamental condition for any work with free-ranging animals is correct species identification. However, in case of bats, information on local species assemblies is frequently limited especially in regions with high biodiversity such as the Neotropics. The bat genus Molossus is a typical example of this, with morphologically similar species often occurring in sympatry. We used a multi-method approach based on molecular, morphometric and acoustic information collected from 962 individuals of Molossus bondae, M. coibensis, and M. molossus captured in Panama. We distinguished M. bondae based on size and pelage coloration. We identified two robust species clusters composed of M. molossus and M. coibensis based on 18 microsatellite markers but also on a more stringently determined set of four markers. Phylogenetic reconstructions using the mitochondrial gene co1 (DNA barcode) were used to diagnose these microsatellite clusters as M. molossus and M. coibensis. To differentiate species, morphological information was only reliable when forearm length and body mass were combined in a linear discriminant function (95.9% correctly identified individuals). When looking in more detail at M. molossus and M. coibensis, only four out of 13 wing parameters were informative for species differentiation, with M. coibensis showing lower values for hand wing area and hand wing length and higher values for wing loading. Acoustic recordings after release required categorization of calls into types, yielding only two informative subsets: approach calls and two-toned search calls. Our data emphasizes the importance of combining morphological traits and independent genetic data to inform the best choice and combination of discriminatory information used in the field. Because parameters can vary geographically, the multi-method approach may need to be adjusted to local species assemblies and populations to be entirely informative.publishe