97 research outputs found

    Evaluation of soil salinity indexes based on bulk electrical conductivity

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    [SPA] Los sensores del suelo que miden conductividad eléctrica (CE) y humedad desempeñan un papel esencial en el control de la salinidad del suelo. Sin embargo, la interpretación precisa de la salinidad del suelo depende del desarrollo de Índices de Salinidad (IS) adecuados. Este trabajo se enfoca en el estudio del potencial de varios IS basados en la CE del medio (ECb), utilizando análisis de regresión para conocer cómo estos IS representan la salinidad del suelo. Los resultados indican que el ECb es un IS eficiente siempre que se mida a humedad constante. Además, la precisión de esta medida aumenta con la humedad del sustrato. La pendiente del ajuste de regresión lineal humedad-ECb se propone como un IS nuevo y fiable. [ENG] Soil sensors that measure electrical conductivity (EC) and moisture play an essential role in monitoring soil salinity. However, the accurate understanding of salinity depends on the development of suitable sensor-based Salinity Indices (SI). This work studied the potential of several SIs based on bulk EC (ECb), which is the only EC directly measured by sensors. Regression studies were performed to know how these SIs describe soil salinity. The results indicate that ECb is an efficient SI as long as humidity is constant. Moreover, its accuracy increases with substrate moisture. The slope of the linear regression fit moisture-ECb is proposed as a novel and reliable SIEsta investigación ha sido financiada por el Ministerio de Ciencia, Innovación y Universidades de España, el Fondo Europeo de Desarrollo Regional, subvención número RTI2018-093997-B-I00, y por la AEI española (subvención número PCI 2019-103608) bajo el programa PRIMA en el marco del proyecto PRECIMED

    Estudio de la marcha en pacientes tratados ortopédicamente de fractura unilateral del calcáneo

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    Veinticinco pacientes afectos de fractura unilateral desplazada articular de calcá- neo fueron tratados mediante inmovilización con yeso, siendo los resultados a los 6 años (rango: 3-10), excelentes en 5 pacientes, buenos en 4, regulares en 7 y malos en 9. De este grupo se excluyeron los afectos de patología local o general asociada, siendo útiles para el estudio de la marcha 12 pacientes a los que se les hizo deambular sobre plataformas dinamométricas para registrar la fuerza de reacción al suelo, demostrando una disminución de la fuerza vertical de apoyo y despegue (F1 y F3) y un aumento estadísticamente significativo del tiempo de apoyo total durante la marcha. Abogamos por la restitución anatómica del calcáneo como medio para mejorar la capacidad funcional del paciente.Twenty-five patients with unilateral displaced joint calcaneus fracture were treated by cast being the results after 6 years (range: 3-10), excellent in 5 patients, good in 4 patients, poor in 7 and bad in 9. We excluded for the study the patients with associated local or general pathology being useful for our study 12 patients. These patients walked on a dynamometric platform in order to analyse floor reaction forces, proving a diminuí ion of vertical support and takeoff forces (Fl and F2), and statistically significant a increase of total support phase during gait

    Evidence for a mixed mass composition at the `ankle' in the cosmic-ray spectrum

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    We report a first measurement for ultra-high energy cosmic rays of the correlation between the depth of shower maximum and the signal in the water Cherenkov stations of air-showers registered simultaneously by the fluorescence and the surface detectors of the Pierre Auger Observatory. Such a correlation measurement is a unique feature of a hybrid air-shower observatory with sensitivity to both the electromagnetic and muonic components. It allows an accurate determination of the spread of primary masses in the cosmic-ray flux. Up till now, constraints on the spread of primary masses have been dominated by systematic uncertainties. The present correlation measurement is not affected by systematics in the measurement of the depth of shower maximum or the signal in the water Cherenkov stations. The analysis relies on general characteristics of air showers and is thus robust also with respect to uncertainties in hadronic event generators. The observed correlation in the energy range around the `ankle' at lg(E/eV)=18.519.0\lg(E/{\rm eV})=18.5-19.0 differs significantly from expectations for pure primary cosmic-ray compositions. A light composition made up of proton and helium only is equally inconsistent with observations. The data are explained well by a mixed composition including nuclei with mass A>4A > 4. Scenarios such as the proton dip model, with almost pure compositions, are thus disfavoured as the sole explanation of the ultrahigh-energy cosmic-ray flux at Earth.Comment: Published version. Added journal reference and DOI. Added Report Numbe

    Atmospheric effects on extensive air showers observed with the Surface Detector of the Pierre Auger Observatory

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    Atmospheric parameters, such as pressure (P), temperature (T) and density, affect the development of extensive air showers initiated by energetic cosmic rays. We have studied the impact of atmospheric variations on extensive air showers by means of the surface detector of the Pierre Auger Observatory. The rate of events shows a ~10% seasonal modulation and ~2% diurnal one. We find that the observed behaviour is explained by a model including the effects associated with the variations of pressure and density. The former affects the longitudinal development of air showers while the latter influences the Moliere radius and hence the lateral distribution of the shower particles. The model is validated with full simulations of extensive air showers using atmospheric profiles measured at the site of the Pierre Auger Observatory.Comment: 24 pages, 9 figures, accepted for publication in Astroparticle Physic

    Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure

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    A percentage of hepatitis C virus (HCV)-infected patients fail direct acting antiviral (DAA)-based treatment regimens, often because of drug resistance-associated substitutions (RAS). The aim of this study was to characterize the resistance profile of a large cohort of patients failing DAA-based treatments, and investigate the relationship between HCV subtype and failure, as an aid to optimizing management of these patients. A new, standardized HCV-RAS testing protocol based on deep sequencing was designed and applied to 220 previously subtyped samples from patients failing DAA treatment, collected in 39 Spanish hospitals. The majority had received DAA-based interferon (IFN) a-free regimens; 79% had failed sofosbuvir-containing therapy. Genomic regions encoding the nonstructural protein (NS) 3, NS5A, and NS5B (DAA target regions) were analyzed using subtype-specific primers. Viral subtype distribution was as follows: genotype (G) 1, 62.7%; G3a, 21.4%; G4d, 12.3%; G2, 1.8%; and mixed infections 1.8%. Overall, 88.6% of patients carried at least 1 RAS, and 19% carried RAS at frequencies below 20% in the mutant spectrum. There were no differences in RAS selection between treatments with and without ribavirin. Regardless of the treatment received, each HCV subtype showed specific types of RAS. Of note, no RAS were detected in the target proteins of 18.6% of patients failing treatment, and 30.4% of patients had RAS in proteins that were not targets of the inhibitors they received. HCV patients failing DAA therapy showed a high diversity of RAS. Ribavirin use did not influence the type or number of RAS at failure. The subtype-specific pattern of RAS emergence underscores the importance of accurate HCV subtyping. The frequency of “extra-target” RAS suggests the need for RAS screening in all three DAA target regions

    7th Drug hypersensitivity meeting: part two

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    No abstract availabl

    Medidas para reducir la exposición de los ciclistas a los principales contaminantes atmosféricos urbanos

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    Recoge los principales resultados generados durante la realización del proyecto LIFE+RESPIRA, llevado a cabo en la ciudad de Pamplona (Navarra, España) por un equipo interdisciplinar constituido por más de 30 investigadores pertenecientes a la Universidad de Navarra, el Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT) y Gestión Ambiental de Navarra (GAN-NIK). El libro, que se ha publicado en castellano y en inglés, se ha dividido en 7 capítulos: 1. ¿Ciudades sostenibles? 2. Exposición de los ciudadanos a la contaminación atmosférica 3. Papel de la vegetación urbana en la calidad del aire 4. Modelos de alta resolución para evaluar la calidad del aire 5. Impactos de la contaminación urbana 6. Movilidad y sostenibilidad urbanas 7. Comunicación y educación ambiental. Este libro pretende ser una guía de utilidad para científicos, gestores y ciudadanos, aportando un conjunto de herramientas que permitan mejorar la calidad de vida de nuestras ciudades. Además, quiere rendir un homenaje a todos los voluntarios ciclistas que han participado en dicho proyecto y que son los verdaderos artífices del mismo, ya que gracias a su dedicación incondicional durante más de dos años, han proporcionado una cantidad ingente de datos sobre la calidad del aire de la ciudad de Pamplona

    Astrophysical Interpretation Of Pierre Auger Observatory Measurements Of The Uhecr Energy Spectrum And Mass Composition

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    The Pierre Auger Observatory Status And Latest Results

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