45 research outputs found

    Monkey see, monkey do: truth-telling in matching algorithms and the manipulation of others

    Get PDF
    We test the effect of the amount of information on the strategies played by others in the theoretically strategy-proof Top Trading Cycles (TTC) mechanism. We find that providing limited information on the strategies played by others has a negative and significant effect in truth-telling rates. Subjects report truthfully more often when either full information or no information on the strategies played by others is available. Our results have potentially important implications for the design of markets based on strategy-proof matching algorithms

    Upscaling the impact of sustainability certification initiatives; Enabling conditions and policy recommendations for regional development

    Get PDF
    Sustainability certification is seen by many as an important means to make supply chains more sustainable. Even though there is some robust evidence on farm-level impacts of certification, and more studies are underway, very little information is available on regional level impacts of certification initiatives. In this study, we offer recommendations to governments, businesses, standard-setting bodies and civil society organisations to help contribute to improvements in impact. Three research questions have been addressed: 1. What impact of initiatives, positive and negative, on farm level but especially on regional level, has been documented on the environment, the society and the economy in production areas? 2. Which contextual factors and regional conditions are required or have proven instrumental for the scaling up of impact and catalysing regional impacts? 3. What can certification initiatives, governments, businesses, international organisations and NGOs do to ensure that the abovementioned conditions are created, supported and promoted? In this study, we refer to the impacts on the regional level as impacts which result from farm-level or local level impacts. To answer the above questions, we reviewed literature sources and conducted semi-structured interviews with stakeholders involved in coffee, cocoa, soy and palm oil supply chains

    Dynamics of liquid He-4 in confined geometries from Time-Dependent Density Functional calculations

    Full text link
    We present numerical results obtained from Time-Dependent Density Functional calculations of the dynamics of liquid He-4 in different environments characterized by geometrical confinement. The time-dependent density profile and velocity field of He-4 are obtained by means of direct numerical integration of the non-linear Schrodinger equation associated with a phenomenological energy functional which describes accurately both the static and dynamic properties of bulk liquid He-4. Our implementation allows for a general solution in 3-D (i.e. no symmetries are assumed in order to simplify the calculations). We apply our method to study the real-time dynamics of pure and alkali-doped clusters, of a monolayer film on a weakly attractive surface and a nano-droplet spreading on a solid surface.Comment: q 1 tex file + 9 Ps figure

    Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels

    Get PDF
    Background So far, more than 170 loci have been associated with circulating lipid levels through genomewide association studies (GWAS). These associations are largely driven by common variants, their function is often not known, and many are likely to be markers for the causal variants. In this study we aimed to identify more new rare and low-frequency functional variants associated with circulating lipid levels. Methods We used the 1000 Genomes Project as a reference panel for the imputations of GWAS data from ~60 000 individuals in the discovery stage and ~90 000 samples in the replication stage. Results Our study resu

    The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape : A Large-Scale Genome-Wide Interaction Study

    Get PDF
    Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and shape change as people grow older and these changes differ substantially between men and women. To systematically screen for age-and/or sex-specific effects of genetic variants on BMI and WHRadjBMI, we performed meta-analyses of 114 studies (up to 320,485 individuals of European descent) with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium. Each study tested the association of up to similar to 2.8M SNPs with BMI and WHRadjBMI in four strata (men 50y, women 50y) and summary statistics were combined in stratum-specific meta-analyses. We then screened for variants that showed age-specific effects (G x AGE), sex-specific effects (G x SEX) or age-specific effects that differed between men and women (G x AGE x SEX). For BMI, we identified 15 loci (11 previously established for main effects, four novel) that showed significant (FDR= 50y). No sex-dependent effects were identified for BMI. For WHRadjBMI, we identified 44 loci (27 previously established for main effects, 17 novel) with sex-specific effects, of which 28 showed larger effects in women than in men, five showed larger effects in men than in women, and 11 showed opposite effects between sexes. No age-dependent effects were identified for WHRadjBMI. This is the first genome-wide interaction meta-analysis to report convincing evidence of age-dependent genetic effects on BMI. In addition, we confirm the sex-specificity of genetic effects on WHRadjBMI. These results may providefurther insights into the biology that underlies weight change with age or the sexually dimorphism of body shape.Peer reviewe

    Histologic evaluation of a biodegradable polyactive/hydroxyapatite membrane

    Get PDF
    Contains fulltext : 22187.PDF (publisher's version ) (Open Access

    Tissue reaction to dacron velour and titanium fibre mesh used for anchorage of percutaneous devices

    Get PDF
    Contains fulltext : 23236___.PDF (publisher's version ) (Open Access

    Quantitative analysis of fibroblast morphology on microgrooved surfaces with various groove and ridge dimensions

    Get PDF
    Contains fulltext : 22838___.PDF (publisher's version ) (Open Access
    corecore