Nota corta. Especies de ácaros fitoseidos (Acari: Phytoseiidae) en manzanos de Río Negro, Argentina

The presence of phytoseiid mites was determined in two unsprayed apple orchards at Cinco Saltos and Cipolletti, Río Negro Province, Argentina. Twenty apple trees were chosen in each orchard and a sample of 10 leaves per tree was taken at seven different sampling dates. Neoseiulus californicus (McGregor), Euseius fructicolus (Gonzalez &Schuster) and Paraseiulus talbii Athias-Henriot were found at Cinco Saltos, and Proprioseiopsis messor (Wainstein), N. californicus and Metaseiulus camelliae (Chant & Yoshida-Shaul) at Cipolletti. Of these species, only N. californicus has previously been reported from the Alto Valle del Río Negro region. Proprioseiopsis messor and Paraseiulus talbii are reported for the first time in South America and on the American Continent respectively.Se llevó a cabo un estudio para determinar la presencia de ácaros fitoseidos en dos plantaciones de manzanos no tratadas con plaguicidas, localizadas en Cinco Saltos y Cipolletti, Provincia de Río Negro, Argentina. Se seleccionaron 20 árboles en cada huerto y se tomó una muestra de 10 hojas por árbol en siete diferentes fechas de muestreo. Neoseiulus. californicus (McGregor), Euseius fructicolus (Gonzalez & Schuster) y Paraseiulus talbii Athias-Henriot fueron las especies identificadas en Cinco Saltos. Proprioseiopsis messor (Wainstein), N. californicus y Metaseiulus camelliae (Chant & Yoshida-Shaul) fueron identificadas en Cipolletti. De las especies recolectadas solamente había sido mencionada previamente N. californicus en la región del Alto Valle del Río Negro. P. messor y P. talbii constituyen nuevas citas para América del Sur y el continente americano, respectivamente

Risk Factors and Clinical Profile of Sapovirus-associated Acute Gastroenteritis in Early Childhood: A Nicaraguan Birth Cohort Study

Background: Sapovirus is increasingly recognized as an important cause of acute gastroenteritis (AGE) in children. We identified risk factors and characterized the clinical profile of sapovirus AGE in a birth cohort in León, Nicaragua. Methods: We conducted a case-control study nested within a birth cohort (n = 444). Fieldworkers conducted weekly household AGE surveillance. AGE stools were tested for sapovirus by reverse transcriptase quantitative polymerase chain reaction. For each first sapovirus episode, we selected 2 healthy age-matched controls and estimated independent risk factors of sapovirus AGE using conditional logistic regression. We compared clinical characteristics of sapovirus AGE episodes with episodes associated with other etiologies and identified co-infections with other enteric pathogens. Results: From June 2017 to July 2019, we identified 63 first sapovirus AGE episodes and selected 126 controls. Having contact with an individual with AGE symptoms and vaginal delivery were independent risk factors for sapovirus AGE. All cases experienced diarrhea, lasting a median 6 days; 23% experienced vomiting. Compared with children with AGE due to another etiology, sapovirus AGE was similar in severity, with less reported fever. Most cases experienced co-infections and were more likely than controls to be infected with diarrheagenic Escherichia coli or astrovirus. Conclusions: Sapovirus was a commonly identified AGE etiology in this Central American setting, and symptoms were similar to AGE associated with other etiologies. The association between vaginal delivery and sapovirus is a novel finding. Gut microbiome composition might mediate this relationship, or vaginal delivery might be a proxy for other risk factors. Further investigation into more specific biological mechanisms is warranted

Non-motor symptom burden in patients with Parkinson's disease with impulse control disorders and compulsive behaviours : results from the COPPADIS cohort

The study was aimed at analysing the frequency of impulse control disorders (ICDs) and compulsive behaviours (CBs) in patients with Parkinson's disease (PD) and in control subjects (CS) as well as the relationship between ICDs/CBs and motor, nonmotor features and dopaminergic treatment in PD patients. Data came from COPPADIS-2015, an observational, descriptive, nationwide (Spain) study. We used the validated Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) for ICD/CB screening. The association between demographic data and ICDs/CBs was analyzed in both groups. In PD, this relationship was evaluated using clinical features and treatment-related data. As result, 613 PD patients (mean age 62.47 ± 9.09 years, 59.87% men) and 179 CS (mean age 60.84 ± 8.33 years, 47.48% men) were included. ICDs and CBs were more frequent in PD (ICDs 12.7% vs. 1.6%, p < 0.001; CBs 7.18% vs. 1.67%, p = 0.01). PD patients had more frequent previous ICDs history, premorbid impulsive personality and antidepressant treatment (p < 0.05) compared with CS. In PD, patients with ICDs/CBs presented younger age at disease onset, more frequent history of previous ICDs and premorbid personality (p < 0.05), as well as higher comorbidity with nonmotor symptoms, including depression and poor quality of life. Treatment with dopamine agonists increased the risk of ICDs/CBs, being dose dependent (p < 0.05). As conclusions, ICDs and CBs were more frequent in patients with PD than in CS. More nonmotor symptoms were present in patients with PD who had ICDs/CBs compared with those without. Dopamine agonists have a prominent effect on ICDs/CBs, which could be influenced by dose

Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

We show the distribution of SARS-CoV-2 genetic clades over time and between countries and outline potential genomic surveillance objectives. We applied three available genomic nomenclature systems for SARS-CoV-2 to all sequence data from the WHO European Region available during the COVID-19 pandemic until 10 July 2020. We highlight the importance of real-time sequencing and data dissemination in a pandemic situation. We provide a comparison of the nomenclatures and lay a foundation for future European genomic surveillance of SARS-CoV-2.Peer reviewe