Draft genome of Haloarcula rubripromontorii strain SL3, a novel halophilic archaeon isolated from the solar salterns of Cabo Rojo, Puerto Rico.

The genus Haloarcula belongs to the family Halobacteriaceae which currently has 10 valid species. Here we report the draft genome sequence of strain SL3, a new species within this genus, isolated from the Solar Salterns of Cabo Rojo, Puerto Rico. Genome assembly performed using NGEN Assembler resulted in 18 contigs (N50 = 601,911 bp), the largest of which contains 1,023,775 bp. The genome consists of 3.97 MB and has a GC content of 61.97%. Like all species of Haloarcula, the genome encodes heterogeneous copies of the small subunit ribosomal RNA. In addition, the genome includes 6 rRNAs, 48 tRNAs, and 3797 protein coding sequences. Several carbohydrate-active enzymes genes were found, as well as enzymes involved in the dihydroxyacetone processing pathway which are not found in other Haloarcula species. The NCBI accession number for this genome is LIUF00000000 and the strain deposit number is CECT9001

Search for Supersymmetry in the Jets + Met + TAUS Final State Using the CMS Detector at the LHC

In this dissertation results are presented from a search for the pair production of heavy colored particles (gluinos, squarks) in R-parity conserving supersymmetric models, in which the lightest supersymmetric particle is a stable and neutral object. The search was performed for events with at least two tau leptons, two highly energetic jets and large missing transverse momentum in the final state on a data sample of proton-proton collisions at sqrt(s) = 7 TeV. The data sample was collected by the Compact Muon Solenoid detector at the Large Hadron Collider in 2011, and it corresponds to an integrated luminosity of 5fb^−1. The tau isolation variable was optimized for this search. The number of events corresponding to standard model processes in the final selection was estimated to be 7.49 ± 0.74 using background estimation techniques based on data. Nine observed events are found to be in agreement with the standard model prediction, and exclusion limits on gluino mass are obtained in the context of supersymmetric models at the 95% confidence level

Fabricación de concreto normal empleando piedra pómez como sustituyente del cemento

En la presente tesis de investigación experimental denominada: “Fabricación de Concreto Normal Utilizando Piedra Pómez como Sustituyente del Cemento”, se utilizará Concreto de tal manera que, incorporará a sus componentes partículas de la Piedra Pómez molida para mejorar sus propiedades mecánicas y químicas del Concreto. Así también como Concreto hecho a bases de sus componentes comunes, para así poder hacer una comparación de los resultados obtenidos de la Resistencia a la Compresión. Para cumplir con este objetivo es necesario moler y dejar en polvo la denominada Piedra Pómez, la cual se caracteriza por tener propiedades puzolánicas. Una vez obtenida la piedra, y después de molida, se procederá a tamizar, llegando a pasar a través del tamiz N° 200, y así asegurar que la piedra cumpla con las exigencias para la realización de este proyecto. El proceso consistió en quitar porcentajes de cemento (10%, 20%, 30%, 40%) y reemplazarlo con puzolana (Piedra Pómez molida), y comparar su Resistencia a la Compresión con Concreto elaborado con 100% de cemento. Se elaboró 8 probetas por cada edad de rotura y por cada porcentaje estimado, obteniendo así valores que se acercan a resultados más óptimos. Se fabricó 105 probetas con porcentaje de puzolana y sin puzolana, las cuales fueron ensayadas y comparadas a los 7, 14 y 28 días de curado, y así se determinó la resistencia alcanzada por cada una de ellas

Higgs phenomenology of supersymmetric economical 3-3-1 model

We explore the Higgs sector in the supersymmetric economical 3-3-1 model and find new features in this sector. The charged Higgs sector is revised i.e., in difference of the previous work, the exact eigenvalues and states are obtained without any approximation. In this model, there are three Higgs bosons having masses equal to that of the gauge bosons--the W and extra X and Y. There is one scalar boson with mass of 91.4 GeV, which is closed to the $Z$ boson mass and in good agreement with present limit: 89.8 GeV at 95% CL. The condition of eliminating for charged scalar tachyon leads to splitting of VEV at the first symmetry breaking, namely, $w \simeq w^\prime$. The interactions among the standard model gauge bosons and scalar fields in the framework of the supersymmetric economical 3-3-1 model are presented. From these couplings, at some limit, almost scalar Higgs fields can be recognized in accordance with the standard model. The hadronic cross section for production of the bilepton charged Higgs boson at the CERN LHC in the effective vector boson approximation is calculated. Numerical evaluation shows that the cross section can exceed 35.8 fb.Comment: 33 pages, 1 figur

3-3-1 Models at Electroweak Scale

We show that in 3-3-1 models there exist a natural relation among the $SU(3)_L$ coupling constant $g$, the electroweak mixing angle $\theta_W$, the mass of the $W$, and one of the vacuum expectation values, which implies that those models can be realized at low energy scales and, in particular, even at the electroweak scale. So that, being that symmetries realized in Nature, new physics may be really just around the corner.Comment: 10 pages, version to be published in Physics Letters

Business consulting report para el Hospital II-1 Luis Heysen Incháustegui

En el ámbito de la salud peruana, los hospitales del Seguro Social de Salud, localizados estratégicamente a lo largo del Perú, se encargan de satisfacer la gran demanda de salud existente brindando prestaciones de salud en prevención, promoción y recuperación entre la población asegurada. En ese sentido, el presente trabajo de investigación ha elaborado un Business Consulting para el Hospital II-1 Luis Heysen Incháustegui en la ciudad de Chiclayo. El propósito de esta consultoría es conocer los factores externos e internos que inciden en el desempeño de la gestión del nosocomio relacionado a un alto embalse quirúrgico, que compromete al establecimiento en no conseguir sus objetivos de largo plazo. Las reuniones con parte de la Dirección del Hospital y el personal asistencial coinciden a que la causa raíz del problema está vinculada con procesos y procedimientos del flujograma de atención del paciente quirúrgico programado. En base a la literatura investigada, se propone implementar un programa innovador denominado “Cirugía al Dia”, iniciativa que establece poner en marcha intervenciones quirúrgicas electivas que no requieren ocupar una cama hospitalaria postoperatoria. De esta manera, la ejecución del plan de implementación espera impactar de manera favorable en la gestión de las cirugías en términos de reducción de costos operativos por paciente, satisfacción en calidad de servicio al paciente y disponibilidad de mayor número de programaciones de intervenciones. Por último, la elaboración de una serie de estimados para tres años, corroboran lo esperado, logrando así alcanzar una mayor producción que resulta en 8127 intervenciones quirúrgicas adicionales. Además, se obtiene una reducción del embalse quirúrgico del 30%; en otras palabras, el número de asegurados en lista de espera para un servicio de cirugía baja a 665. Y se alcanza un ahorro por concepto de pagos de pacientes fuera de Lambayeque en un rango de S/ 1.2 millones y S/ 1.6 millones anuales.In the field of Peruvian health, the Social Health Security hospitals, strategically located throughout Peru, are in charge of satisfying the great demand for existing health by providing health benefits in prevention, promotion and recovery among the insured. In this sense, the present research work has prepared a Business Consulting for Hospital II-1 Luis Heysen Incháustegui in the city of Chiclayo. The purpose of this consultancy is to know the external and internal factors that affect the performance of hospital management related to a high surgical reservoir, which commits the establishment not to achieve its long-term objectives. The meetings with part of the Hospital Directorate and the healthcare personnel agree that the cause of the problem is linked to processes and procedures of the care flow chart of the scheduled surgical patient. Based on the researched literature, it is proposed to implement an innovative program called "Surgery to the Day", an initiative that establishes the implementation of elective surgical interventions that do not require occupying a postoperative hospital bed. In this way, the execution of the implementation plan expects to have a favorable impact on the management of surgeries in terms of reduction of operating costs per patient, satisfaction in the quality of patient service and availability of a greater number of intervention programs. Finally, the preparation of a series of estimates for three years corroborates what was expected, thus achieving a higher production resulting in 8127 additional surgical interventions. In addition, a reduction of the surgical reservoir of 30% is obtained; In other words, the number of insured persons on the waiting list for a surgery service drops to 665. And there is savings for patient payments outside Lambayeque in a range of S / 1.2 million and S / 1.6 million annually

Carbon nanotube-Cu hybrids enhanced catalytic activity in aqueous media

V. González, O. Martín and J. Baselga wish to thank Ministerio de Economía y Competitividad for funding through Grant MAT2010-17091. Authors also wish to thank to Sofía M. Vega for XPS measurements, Juan P. Fernández for TGA measurements and Lakshmy Pulickal Rajukumar for EDX measurements. C. Martín-Alberca thanks the University of Alcalá for his pre-doctoral Grant

Myocardial and circulating levels of microRNA-21 reflect left ventricular fibrosis in aortic stenosis patients

Background: Various human cardiovascular pathophysiological conditions associate aberrant expression of microRNAs (miRNAs) and circulating miRNAs are emerging as promising biomarkers. In mice, myocardial miR-21 overexpression is related to cardiac fibrosis elicited by pressure overload. This study was designed to determine the role of myocardial and plasmatic miR-21 in the maladaptive remodeling of the extracellular matrix induced by pressure overload in aortic stenosis (AS) patients and the clinical value of miR-21 as a biomarker for pathological myocardial fibrosis. Methods: In left ventricular biopsies from 75 AS patients and 32 surgical controls, we quantified the myocardial transcript levels of miR-21, miR-21-targets and ECM- and TGF-β-signaling-related elements. miR-21 plasma levels were determined in 25 healthy volunteers and in AS patients. In situ hybridization of miR-21 wasperformed in myocardial sections. Results: The myocardial and plasma levels of miR-21 were significantly higher in the AS patients compared with controls and correlated directly with the echocardiographic mean transvalvular gradients. miR-21 overexpression was confined to interstitial cells and absent in cardiomyocytes. Using bootstrap validated multiple linear regression, the variance in myocardial collagen expression was predicted by myocardial miR-21 (70% of collagen variance) or plasma miR-21 (52% of collagen variance), together with the miR-21 targets RECK and PDCD4, and effectors of TGF-β signaling. Conclusions: Our results support the role of miR-21 as a regulator of the fibrotic process that occurs in response to pressure overload in AS patients and underscore the value of circulating miR-21 as a biomarker for myocardial fibrosis