1,513 research outputs found
Recommended from our members
Myosin-I nomenclature.
We suggest that the vertebrate myosin-I field adopt a common nomenclature system based on the names adopted by the Human Genome Organization (HUGO). At present, the myosin-I nomenclature is very confusing; not only are several systems in use, but several different genes have been given the same name. Despite their faults, we believe that the names adopted by the HUGO nomenclature group for genome annotation are the best compromise, and we recommend universal adoption
Conjunctions of Among Constraints
Many existing global constraints can be encoded as a conjunction of among
constraints. An among constraint holds if the number of the variables in its
scope whose value belongs to a prespecified set, which we call its range, is
within some given bounds. It is known that domain filtering algorithms can
benefit from reasoning about the interaction of among constraints so that
values can be filtered out taking into consideration several among constraints
simultaneously. The present pa- per embarks into a systematic investigation on
the circumstances under which it is possible to obtain efficient and complete
domain filtering algorithms for conjunctions of among constraints. We start by
observing that restrictions on both the scope and the range of the among
constraints are necessary to obtain meaningful results. Then, we derive a
domain flow-based filtering algorithm and present several applications. In
particular, it is shown that the algorithm unifies and generalizes several
previous existing results.Comment: 15 pages plus appendi
Professional quality of life and burnout amongst radiation oncologists:The impact of alexithymia and empathy
Background and purpose: Different factors may influence the professional quality of life of oncology professionals. Among them, personality traits, as alexithymia and empathy, are underinvestigated. Alexithymia is about deficits in emotion processing and awareness. Empathy is the ability to understand another's 'state of mind'/emotion. The PROject on BurnOut in RadiatioN Oncology (PRO BONO) assesses professional quality of life, including burnout, in the field of radiation oncology and investigates alexithymia and empathy as contributing factors. Material and methods: An online survey was conducted amongst ESTRO members. Participants completed 3 validated questionnaires for alexithymia, empathy and professional quality of life: (a) Toronto Alexithymia Scale; (b) Interpersonal Reactivity Index; (c) Professional Quality of Life Scale. The present analysis, focusing on radiation/clinical oncologists, evaluates Compassion Satisfaction (CS), Secondary Traumatic Stress (STS) and Burnout and correlates them with alexithymia and empathy (empathic concern, perspective taking and personal distress) with generalized linear modeling. Significant covariates on univariate linear regression analysis were included in the multivariate linear regression model. Results: A total of 825 radiation oncologists completed all questionnaires. A higher level of alexithymia was associated to decreased CS (beta:-0.101; SE: 0.018; p <0.001), increased STS (beta: 0.228; SE: 0.018; p <0.001) and burnout (beta: 0.177; SE: 0.016; p <0.001). A higher empathic concern was significantly associated to increased CS (beta: 0.1.287; SE: 0.305; p = 0.001), STS (beta: 0.114; SE: 0.296; p <0.001), with no effect on burnout. Personal distress was associated to decreased CS (beta:-1.423; SE: 0.275; p <0.001), increased STS (beta: 1.871; SE: 0.283; p <0.001) and burnout (beta: 1.504; SE: 0.245; p <0.001). Conclusions: Alexithymic personality trait increased burnout risk, with less professional satisfaction. Empathic concern was associated to increased stress, without leading to burnout, resulting in higher professional fulfillment. These results may be used to benchmark preventing strategies, such as work-hour restrictions, peer support, debriefing sessions, and leadership initiatives for professionals at risk. (c) 2020 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 147 (2020) 162-16
Functional Effects of Parasites on Food Web Properties during the Spring Diatom Bloom in Lake Pavin: A Linear Inverse Modeling Analysis
This study is the first assessment of the quantitative impact of parasitic chytrids on a planktonic food web. We used a carbon-based food web model of Lake Pavin (Massif Central, France) to investigate the effects of chytrids during the spring diatom bloom by developing models with and without chytrids. Linear inverse modelling procedures were employed to estimate undetermined flows in the lake. The Monte Carlo Markov chain linear inverse modelling procedure provided estimates of the ranges of model-derived fluxes. Model results support recent theories on the probable impact of parasites on food web function. In the lake, during spring, when âinedibleâ algae (unexploited by planktonic herbivores) were the dominant primary producers, the epidemic growth of chytrids significantly reduced the sedimentation loss of algal carbon to the detritus pool through the production of grazer-exploitable zoospores. We also review some theories about the potential influence of parasites on ecological network properties and argue that parasitism contributes to longer carbon path lengths, higher levels of activity and specialization, and lower recycling. Considering the âstructural asymmetryâ hypothesis as a stabilizing pattern, chytrids should contribute to the stability of aquatic food webs
Measurement of CNGS muon neutrino speed with Borexino
We have measured the speed of muon neutrinos with the Borexino detector using
short-bunch CNGS beams. The final result for the difference in time-of-flight
between a =17 GeV muon neutrino and a particle moving at the speed of light
in vacuum is {\delta}t = 0.8 \pm 0.7stat \pm 2.9sys ns, well consistent with
zero.Comment: 6 pages, 5 figure
Recommended from our members
Antarctic last interglacial isotope peak in response to sea ice retreat not ice-sheet collapse
Several studies have suggested that sea-level rise during the last interglacial implies retreat of the West Antarctic Ice Sheet (WAIS). The prevalent hypothesis is that the retreat coincided with the peak Antarctic temperature and stable water isotope values from 128,000 years ago (128âka); very early in the last interglacial. Here, by analysing climate model simulations of last interglacial WAIS loss featuring water isotopes, we show instead that the isotopic response to WAIS loss is in opposition to the isotopic evidence at 128âka. Instead, a reduction in winter sea ice area of 65±7% fully explains the 128âka ice core evidence. Our finding of a marked retreat of the sea ice at 128âka demonstrates the sensitivity of Antarctic sea ice extent to climate warming
In-situ evidence for dextral active motion at the Arabia-India plate boundary
International audienceThe Arabia-India plate boundary--also called theOwen fracture zone--is perhaps the least-known boundary among large tectonic plates1-6. Although it was identified early on as an example of a transform fault converting the divergent motion along the Carlsberg Ridge to convergent motion in the Himalayas7, its structure and rate of motion remains poorly constrained. Here we present the first direct evidence for active dextral strike-slip motion along this fault, based on seafloor multibeam mapping of the Arabia-India-Somalia triple junction in the northwest Indian Ocean. There is evidence for 12km of apparent strike-slip motion along the mapped segment of the Owen fracture zone, which is terminated to the south by a 50-km-wide pull-apart basin bounded by active faults. By evaluating these new constraints within the context of geodetic models of global plate motions, we determine a robust angular velocity for the Arabian plate relative to the Indian plate that predicts 2-4mmyrâ1 dextral motion along the Owen fracture zone. This transformfault was probably initiated around 8 million years ago in response to a regional reorganization of plate velocities and directions8-11, which induced a change in configuration of the triple junction. Infrequent earthquakes of magnitude 7 and greater may occur along the Arabia-India plate boundary, unless deformation is in the formof aseismic creep
Glaciation Effects on the Phylogeographic Structure of Oligoryzomys longicaudatus (Rodentia: Sigmodontinae) in the Southern Andes
The long-tailed pygmy rice rat Oligoryzomys longicaudatus (Sigmodontinae), the major reservoir of Hantavirus in Chile and Patagonian Argentina, is widely distributed in the Mediterranean, Temperate and Patagonian Forests of Chile, as well as in adjacent areas in southern Argentina. We used molecular data to evaluate the effects of the last glacial event on the phylogeographic structure of this species. We examined if historical Pleistocene events had affected genetic variation and spatial distribution of this species along its distributional range. We sampled 223 individuals representing 47 localities along the species range, and sequenced the hypervariable domain I of the mtDNA control region. Aligned sequences were analyzed using haplotype network, Bayesian population structure and demographic analyses. Analysis of population structure and the haplotype network inferred three genetic clusters along the distribution of O. longicaudatus that mostly agreed with the three major ecogeographic regions in Chile: Mediterranean, Temperate Forests and Patagonian Forests. Bayesian Skyline Plots showed constant population sizes through time in all three clusters followed by an increase after and during the Last Glacial Maximum (LGM; between 26,000â13,000 years ago). Neutrality tests and the âgâ parameter also suggest that populations of O. longicaudatus experienced demographic expansion across the species entire range. Past climate shifts have influenced population structure and lineage variation of O. longicaudatus. This species remained in refugia areas during Pleistocene times in southern Temperate Forests (and adjacent areas in Patagonia). From these refugia, O. longicaudatus experienced demographic expansions into Patagonian Forests and central Mediterranean Chile using glacial retreats
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of âs = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pTâ„20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60â€pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2â€{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
- âŠ