Proving and improving – evaluating policy engagement is an opportunity for researchers and institutions to learn as well as demonstrate impact.

The challenges of evaluating the contribution of research to policy making are well documented. In this post Chris Roche, Alana Tomlin, Ujjwal Krishna and Will Pryor outline seven principles for effective monitoring, evaluation and learning for policy engagement. They were developed through consultation with researchers, support staff and others in a range of science and humanities disciplines at the University of Oxford and beyond. The authors suggest if research institutions want to be able to better demonstrate policy impact, they should approach monitoring and evaluation by building on the intrinsic motivation of researchers to learn and improve, rather than as an exercise in simply recording and proving impact

Mass segregation in young compact star clusters in the Large Magellanic Cloud: II. Mass Functions

We review the complications involved in the conversion of stellar luminosities into masses and apply a range of mass-to-luminosity relations to our Hubble Space Telescope observations of the young LMC star clusters NGC 1805 and NGC 1818. Both the radial dependence of the mass function (MF) and the dependence of the cluster core radii on mass indicate clear mass segregation in both clusters at radii r <= 20-30'', for masses in excess of ~1.6-2.5 Msun. This result does not depend on the mass range used to fit the slopes or the metallicity assumed. It is clear that the cluster MFs, at any radius, are not simple power laws. The global and the annular MFs near the core radii appear to be characterised by similar slopes in the mass range (-0.15 <= log m/Msun <= 0.85), the MFs beyond r >= 30'' have significantly steeper slopes. We estimate that while the NGC 1818 cluster core is between ~5 and ~30 crossing times old, the core of NGC 1805 is likely $\lesssim 3-4$ crossing times old. However, since strong mass segregation is observed out to ~6 Rcore and ~3 Rcore in NGC 1805 and NGC 1818, respectively, it is most likely that significant primordial mass segregation was present in both clusters, particularly in NGC 1805.Comment: 16 pages, incl. 9 embedded postscript figures, MNRAS, resubmitted (referee's comments included

Dead-box proteins: a family affair—active and passive players in RNP-remodeling

DEAD-box proteins are characterized by nine conserved motifs. According to these criteria, several hundreds of these proteins can be identified in databases. Many different DEAD-box proteins can be found in eukaryotes, whereas prokaryotes have small numbers of different DEAD-box proteins. DEAD-box proteins play important roles in RNA metabolism, and they are very specific and cannot mutually be replaced. In vitro, many DEAD-box proteins have been shown to have RNA-dependent ATPase and ATP-dependent RNA helicase activities. From the genetic and biochemical data obtained mainly in yeast, it has become clear that these proteins play important roles in remodeling RNP complexes in a temporally controlled fashion. Here, I shall give a general overview of the DEAD-box protein family