15 research outputs found
Estudo Preliminar das Propriedades Psicométricas do Inventário de Lateralidade de Edinburgh numa Amostra de Adultos da População Portuguesa
- Publication venue
- 'International Society for Managing and Technical Editors (ISMTE)'
- Publication date
- 01/01/2016
- Field of study
Introdução: A lateralidade é a diferença na capacidade de controlo entre os dois lados do corpo. Os métodos utilizados para avaliar a lateralidade manual incluem a observação efetiva do uso do membro dominante ou a aplicação de inventários respondidos pelo próprio indivíduo avaliado. O Inventário de Lateralidade de Edinburgh (EHI) é o instrumento mais utilizado para avaliar a lateralidade manual.
Apesar do seu uso amplo, em Portugal não existem estudos que avaliem a sua validade e fidedignidade.
Objetivos: Estudar as propriedades psicométricas do Inventário de Lateralidade de Edinburgh numa amostra da população portuguesa.
Métodos: A amostra é constituída por 290 pessoas (135 homens e 155 mulheres), com idades compreendidas entre os 18 e os 65 anos. Todos os participantes preencheram uma declaração de consentimento informado e uma bateria de testes neuropsicológicos
Resultados: A média no EHI foi de 62,36 (DP = 38,00). Os resultados demonstraram que das seis variáveis sociodemográficas (idade, sexo, escolaridade, zona de residência, regiões e profissão) três apresentaram ter influência significativa nas pontuações do EHI: idade, zona de residência e regiões. A confiabilidade e a
estabilidade temporal do EHI apresentaram resultados adequados. A análise fatorial confirmatória mostrou que o modelo não é melhor explicado por um fator. Para dois fatores o modelo continua a não ser adequado.
Conclusão: Apesar de termos obtido uma boa consistência interna não nos é possível considerar este teste como o mais adequado para medir o constructo da lateralidade. / Introduction: The handedness is the difference in the control capacity between the two sides of the body. The methods used to evaluate the manual handedness include the effective observation of the use of dominant member or application of inventories answered by the person assessed. The Edinburgh Handedness Inventory (EHI) is the most used to evaluate manual handedness. Even though being widely used, in Portugal there are no studies that measure its validity and reliability.
Objective: To study the psychometric properties of Edinburgh Handedness Inventory in a Portuguese sample.
Methods: The sample consists of 290 people (135 men and 155 women), aged between 18 and 65 years. All participants filled an informed consent form and a battery of neuropsychological tests.
Results: The average in EHI was 62.36 (SD = 38.00). The results showed that 3 of 6 sociodemographic variables showed significant influence in EHI scores. The reliability and temporal stability of EHI were adequate. Confirmatory factor analysis showed that the model is not better explained by one factor. A two-factor model was not also suitable.
Conclusion: Even though we got a good internal consistency we cannot consider this test as the most appropriate for measuring the handedness construct
Characterisation of microbial attack on archaeological bone
- Author
- Abrantes Ana M
- Abreu Ana C
- Abreu Renato
- Abreu Renato
- Abreu Wilson
- Acedo Guadalupe
- Afonso Carlos
- Afreixo Vera
- Agudelo Mª E
- Alarcão Violeta
- Albuquerque Carlos
- Albuquerque Carlos
- Albuquerque Carlos
- Alencar Liana
- Alferes Valentim R
- Aliseda Isabel R
- Almada Lívia F
- Almeia António
- Almeida Ana
- Almeida Ana
- Almeida António
- Almeida António
- Almeida Armando
- Almeida Armando
- Almeida Fabrícia M
- Almeida Henrique
- Almeida Henrique A
- Almeida Henrique A
- Almeida Inês
- Almeida Jorge
- Almeida José P
- Almeida Maria
- Almeida Pedro
- Almeida Sidalina
- Alvarenga-Martins Nathália
- Alves B.
- Alves B.
- Alves Celeste
- Alves Dina
- Alves Gilberto
- Alves Helder
- Alves Josiane
- Alves José M
- Alves Juliana
- Alves Júlia M
- Alves Nuno
- Alves Nuno
- Alves Samuel
- Amado Diogo
- Amado João
- Amado Sandra
- Amaral Ana P
- Amaral Ana P
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Amaral Odete
- Ambrósio Sara
- Amendoeira José
- Amorim Ana
- Amorim Ana P
- Amorim Helena
- Andrade Diogo
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade Isabel
- Andrade J. A
- Andrade Karizia V
- Andrade Renato
- Andrade Renato
- Andrade Susana
- Antunes Ana
- Antunes Ana
- Antunes Cristina
- Antunes Lígia
- Antunes Sandra
- Antunes Sandra
- Aparício Graça
- Aparício Graça
- Aparício José
- Apolinário-Hagen Jennifer
- Apolinário-Hagen Jennifer
- Aquino Caroline Q
- Aquino Caroline Q
- Aquino Priscila S
- Aquino Priscila S
- Araujo André R
- Araújo Beatriz
- Araújo Elsa
- Araújo Lia
- Araújo Odete
- Araújo Odete
- Araújo Patrícia
- Araújo Patrícia
- Araújo Patrícia
- Armas-Gonzalez Yadira
- Arreguy-Sena Cristina
- Arreguy-Sena Cristina
- Ascenso Rita T
- Ascenso Rita T
- Assunção Victor
- Augusto Cláudia
- Avelelas Francisco
- Ayoub Rodrigo
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azeredo Zaida
- Azevedo Julieta
- Azevedo Julieta
- Azevedo Marcelo
- Azevedo Maria H
- Azevedo Mª H
- Azevedo Tatiana
- Azzalis L.
- Baffour Gabriel
- Baffour Gabriel
- Bairros Keila
- Baixinho Cristina L
- Bajo Roberto
- Baltazar Ana L
- Barbeiro Ana P
- Barbosa Flávio
- Barbosa Tiago
- Barreira Eduarda
- Barreiros Luísa
- Barros Luísa
- Barros Luísa
- Barros Teresa
- Barroso Isabel
- Barroso Isabel
- Barroso Isabel
- Barroso João
- Basto Marta L
- Basto Marta L
- Basto Marta L
- Bastos Fernanda
- Bastos Fernanda
- Batalha Joana
- Batista Marco
- Batista Marco
- Batista Marco
- Batista Rita
- Baylina Pilar
- Becerra Isabel A
- Bellém Fernando
- Bellém Fernando
- Belo Pedro
- Benevides Joana
- Benevides Joana
- Bento Elisabete
- Bento Elisabete
- Bento Sandrina
- Bento Teresa
- Bergland Astrid
- Bernardes Lúcia G
- Bernardes Tiago
- Bernardo Helena
- Bexiga Filipa
- Bianchini Bruna
- Bizarro Carla
- Björklund Anita
- Blanco Valeriana G
- Boavida José
- Bonfim Luís
- Bordin Ronaldo
- Bordin Ronaldo
- Bordini Magali
- Borges Raphaelle
- Botelho Mª F
- Braga Fátima
- Braga Luciene
- Braga Luciene M
- Braga Luciene M
- Braga Margarida
- Branco Marco
- Brandão Daniela
- Brandão Daniela
- Brandão Frederico
- Brandão Piedade
- Brandão Teresa
- Bravo Rafael
- Bravo Rafael
- Breda São J
- Brito Alice
- Brito António
- Brito Irma
- Brito Luísa S
- Brito Nuno
- Brooks Dina
- Brunhoso Germana
- Brás Carina
- Brás Manuel
- Brêda Mª S J
- Bye Asta
- Caballero Francisco P
- Caballero Francisco P
- Caballero Francisco P
- Cabral Cremilde
- Cabral Gil
- Cabral Isabel
- Cabral Joana
- Cabral Lídia
- Cabral Priscila P
- Cabrita José
- Caceiro Elisa F
- Cadorio Inês
- Caeiro Patrícia
- Caldeira Suzana N
- Calha António
- Calha António
- Calvo Cristina
- Calvo Mª C
- Camarinha Luís
- Camarinha Luís
- Camarneiro Ana
- Camarneiro Ana
- Caminha Madson
- Campi Liliana
- Campofiorito C.
- Campos Maria
- Campos Maria
- Campos Mariana
- Campos Mª J
- Capelas Sylvie
- Cardoso Américo
- Cardoso Andreia
- Cardoso Ilda
- Cardoso Margarida
- Cardoso Mário E
- Cardoso Sara
- Cardoso Susana
- Carecho Nélio
- Carmen Barriga
- Carmo A.
- Carmo Bruno M
- Carneiro Juliana
- Carneiro Lara
- Carneiro Lara
- Carneiro M. A
- CaroMinghelli Eulália
- Carreira Diana
- Carreiras Diogo
- Carrão Luís
- Carvalhais Maribel
- Carvalhais Maribel
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- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Carla
- Carvalho Célia B
- Carvalho Célia B
- Carvalho Célia B
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Daniel
- Carvalho Francisco L
- Carvalho Inês
- Carvalho Joana
- Carvalho Lisiane L
- Carvalho Lisiane L
- Carvalho Lucinda
- Carvalho Nelma
- Carvalho Rosa
- Carvalho Rui
- Carvalho Sara
- Carvalho Sérgio
- Carvalho Teresa
- Carvalho Teresa
- Carvalho Tiago
- Carvalho Yara M
- Casalta-Lopes João
- Casas-Novas Mónica
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Caseiro Armando
- Casimiro Ana P
- Castilho Amélia
- Castilho Amélia
- Castilho Amélia
- Castilho Amélia
- Castilho Paula
- Castro Conceição
- Castro Régia B
- Castuera Ruth J
- Catarino Elisabete
- Catarino Helena
- Catarino Helena
- Catarino Helena
- Catarino Helena
- Catela David
- Cavalheiro Luís
- Cavalheiro Luís
- Certo Ana
- Cervato-Mancuso Ana M
- Cezanne Catarina
- Charepe Zaida
- Charepe Zaida
- Cheio Mónica
- Chen Gang
- Chung Wu F
- Clara João G
- Coelho Alexandre
- Coelho André
- Coelho Carina
- Coelho Elza S
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- Coelho Inês
- Coelho Luís
- Coelho Luís
- Coelho P.
- Coelho Patrícia
- Coelho Patrícia
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- Colaço Armanda
- Colaço Diogo
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- Collado-Mateo Daniel
- Combadão Jaime
- Conceição Milena A
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- Cordeiro Eugénio
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Marina
- Cordeiro Raul
- Correia André
- Correia Jony
- Correia Telma
- Costa Ana R
- Costa André
- Costa Cláudia
- Costa Diana
- Costa Diana
- Costa Emília
- Costa Joyce O
- Costa Joyce O
- Costa Pablo O
- Costa Ricardo
- Costa Rui
- Costa Tânia
- Costa Tânia
- Costa Vanessa
- Coucelo Tiago
- Coutinho André P
- Coutinho Paula
- Couto Cristina
- Couto Diana
- Couto Margarida
- Couto Margarida
- Cova Marco P
- Cruz Agostinho
- Cruz Agostinho
- Cruz Agostinho
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- Cruz x
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- Cunha Marina
- Cunha Marina
- Cunha Marina
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- Cunha Marina
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- Cândido Anabela
- César Ana F
- Da Motta Carolina
- Da Motta Carolina
- Da Motta Carolina
- Daniel Fernanda
- Dantas Estélio
- Deodato Sérgio
- Desouzart Gustavo
- Dias Alberto P
- Dias António
- Dias Hélia
- Dias Sara S
- Dias Sara S
- Dias Sara S
- Dias Tiago
- Dinis Alexandra
- Dinis Alexandra
- Dixe Anjos
- Dixe Anjos
- Dixe Anjos
- Dixe Maria
- Dixe Maria D A
- Dixe Maria D A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Dixe Mª A
- Domingos Joana
- Domingos Samuel
- Domingues Cátia
- Domingues Gabriela
- Domingues J. N
- Dreyer Laysa C
- Duarte Catarina
- Duarte Diana
- Duarte Diana
- Duarte Hugo
- Duarte Hugo
- Duarte João
- Duarte João
- Duarte João
- Duarte Mafalda
- Duarte Nuno
- Duarte Soraia
- Duarte Soraia
- Escanciano Susana R
- Escoval Ana
- Espada Mário
- Esteves Mª R
- Estevez Gustavo L
- Estrela Jéssica
- Evangelista Diana
- Faria Luís
- Faria Luís
- Faria Melissa
- Faria Paula
- Faria Paula
- Faustino António
- Faustino António
- Faustino António
- Fernandes Adília
- Fernandes Ana R
- Fernandes Andreia
- Fernandes Beatriz
- Fernandes Helder M
- Fernandes Jorge C
- Fernandes Morgana C
- Fernandes Patrícia
- Fernandes Patrícia
- Fernandes Paula
- Fernandes Paula O
- Fernandes Paula O
- Fernandes Renato
- Fernandes Rosina
- Fernandes Rosina
- Fernandes Rosina
- Fernandes Telma
- Fernandez Mª J L
- Ferraz Maira
- Ferraz Vera
- Ferreira Ana
- Ferreira Ana
- Ferreira Ana
- Ferreira Ana
- Ferreira António
- Ferreira António
- Ferreira Carlos
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Cláudia
- Ferreira Dora
- Ferreira Eduardo
- Ferreira Eduardo
- Ferreira Irina
- Ferreira José
- Ferreira José
- Ferreira José P
- Ferreira Lino
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Manuela
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Margarida
- Ferreira Nelson
- Ferreira P.
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Paulo P
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro
- Ferreira Pedro L
- Ferreira Regina
- Ferrito Cândida
- Ferro-Lebres Vera
- Festas Clarinda
- Figueiredo Amélia
- Figueiredo Ana G
- Figueiredo Daniela
- Figueiredo J.
- Figueiredo João
- Figueiredo João P
- Figueiredo João P
- Figueiredo João P
- Figueiredo Mª C
- Figueiredo Mª H
- Figueiredo Mª H
- Figueiredo Paulo
- Filho Braulio L
- Filho João G
- Filho João G
- Filho João G
- Filipe Vítor
- Fiorin Bruno H
- Fleig Tânia C
- Fleig Tânia C
- Fonseca Ana R
- Fonseca F.
- Fonseca F.
- Fonseca Virgínia
- Fonseca Virgínia
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fonseca-Pinto Rui
- Fontana Karine C
- Fontes-Ribeiro Carlos
- Forte Henriqueta D
- Fotschl Ulrike
- Frade João G
- Frade João G
- Frade João G
- Francisco Irene
- Franco Débora
- Franco-Borges Graciete
- Freire Ana
- Freitas Alberto
- Freitas Gregório
- Freitas Gregório
- Freitas João
- Freitas Kátia
- Freitas Maria
- Freitas Otília
- Freitas Otília
- Freitas Vívien A
- Frigo Leticia
- Froemming Miriam B
- Fuentes-Broto Lorena
- Furtado Alessandra S
- Furtado G.
- Furtado Guilherme
- Furtado Guilherme
- Furtado Guilherme E
- G.Silva Anne
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel António
- Gabriel Joaquim
- Gabriel Joaquim
- Galhardo Ana
- Galhardo Ana
- Galhardo Ana
- Galhardo Ana
- Galvão Ana
- Galvão Ana
- Galvão Ana
- Galvão Sofia
- Gama Ester
- Gama João
- Ganho-Ávila Ana
- Garcia Ana P
- Garcia Inês
- Garcia Teresa
- Garcia-Gordillo Miguel A
- Garcia-Gordillo Miguel A
- Garrido António
- Gaspar Filomena
- Gaspar Filomena
- Gaudêncio Iris
- Gehrke F.
- Gehrke F.
- Gisin Stefan
- Glória Margarida
- Gomes Ana A
- Gomes Ana A
- Gomes Antônio T
- Gomes Catarina
- Gomes Fernando
- Gomes José
- Gomes José C
- Gomes José H
- Gomes José H
- Gomes José H
- Gomes João
- Gomes João
- Gomes João
- Gomes João
- Gomes João
- Gomes Lisa
- Gomes Maria
- Gomes Mª J
- Gomes Pedro
- Gomes Sofia
- Gomez Inmaculada R
- Gonzalez Estefania P
- González Jesús A
- Gonçalves Amadeu
- Gonçalves Ana
- Gonçalves Ana
- Gonçalves Ana C
- Gonçalves Guilherme
- Gonçalves Liliana
- Gonçalves Narcisa
- Gonçalves Rita
- Gonçalves Rodrigo
- Gonçalves Rui
- Gonçalves Rui
- Gonçalves Óscar
- Gordo Clementina
- Gordo Sara
- Goulart Cássia L
- Goulão Beatriz
- Grande Carla
- Granjo Paulo
- Graveto João
- Graveto João
- Graveto João
- Graveto João
- Graça Anabela
- Graça Pedro
- Guedelha Daniel
- Guedes Jenifer
- Guedes Jenifer
- Guedes Joana
- Guerra Magda
- Guerreiro Sabrina L
- Guerrero Jose T
- Guerrero Jose T
- Guerrero José T
- Guerrero José T
- Guimarães Pedro
- Guimarães Teresa
- Guimarães Teresa
- Gusi Narcis
- Gutierrez Milagros L
- Hall Andreia
- Heitor Mª J
- Henriques Carolina
- Henriques Carolina G
- Henriques Mª A
- Hernandez-Martinez Francisco J
- Hernandez-Martinez Francisco J
- Hernández-Martínez Francisco-José
- Hesse Camilla
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Honório Samuel
- Horta Lina G
- Huertas Mª J T
- Iezzi Angelo
- Jardim Ana
- Jardim Helena G
- Jardim Jacinto
- Jesus C.
- Jesus C.
- Jesus Carlos
- Jesus Luís
- Jesus Rita
- Jesus Ângelo
- Jesus Ângelo
- Jesus Ângelo
- Jesus Ângelo
- Jimenez Nuria R
- Jimenez-Castuera Ruth
- Jimenez-Diaz Juan F
- Jimenez-Diaz Juan F
- Jimenez-Rodriguez Carla
- Jiménez-Díaz Juan-Fernando
- Jiménez-Díaz Juan-Fernando
- Jiménez-Rodríguez Carla
- Jordão Célia
- Jorge Arminda
- José Helena
- João Paulo V
- João Paulo V
- Jácome Cristina
- Jácome Cristina
- Kaliniczenco A.
- Kniess Rosiane
- Kranz Luís F
- Kranz Luís F
- Kraus Teresa
- Kraus Teresa
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia
- Kretzer Marcia R
- Kretzer Márcia R
- Kurcgant Paulina
- Lacerda Josimari T
- Lacerda Josimari T
- Lacerda Josimari T
- Lage Isabel
- Lagoa Matilde
- Lains Jorge
- Lapa Leila
- Laranjeira Carlos
- Laranjo Mafalda
- Leal Jéssica
- Lebre Paula
- Lebre Sara
- Lee Huei D
- Leitão Catarina
- Leitão Céu
- Leitão Céu
- Leitão José A
- Lessa Paula A
- Leça Andrea
- Lima Adman S
- Lima Cristóvão F
- Lima Teresa M
- Lima Vera
- Lima-Basto Marta
- Lindo João
- Lindo João
- Lirk Gerald
- Lobato João
- Lobão Catarina
- Lopes Albino
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- Lopes Carla
- Lopes Elisa
- Lopes José C
- Lopes João
- Lopes Luci S
- Lopes Nuno
- Lopes Nuno V
- Lopes Nuno V
- Lopes Rui S
- Lopes Sara
- Lopes Saudade
- Loura Raquel
- Loureiro Isabel
- Loureiro Mª H
- Loureiro Mª H
- Loureiro Mª H
- Lourenço Georgina
- Lourenço Marina
- Louro Clarisse
- Louro Clarisse
- Louro Mª C
- Lousada Marisa
- Lousada Marisa
- Lousada Marisa
- Lumini José
- Luz Leonardo
- Luz Leonardo
- Luz Tatiana
- Luz Tatiana D
- Luís Henrique
- Luís Luís
- Luís Mª J
- Luís Sara
- Macedo Ana P
- Macedo António
- Macedo António
- Machado Idalina
- Machado Mª M
- Machado Patrícia O
- Machado Paulo
- Machado Paulo
- Machado Sara
- Madeira Teresa
- Madureira António
- Madureira António
- Magajewski Flávio
- Magalhães Carlos
- Magalhães Celina
- Magalhães Cátia
- Magalhães Cátia
- Magalhães Cátia
- Maia Ana S
- Maia Ana S
- Maia Ana S
- Maia Ana S
- Maia Bruno
- Maia Bruno
- Maia Carla
- Malheiro Isabel
- Malheiro Isabel
- Mangas Catarina
- Mangas Catarina
- Manso Conceição
- Manso M. C
- Marante Nídia
- Margarida Couto
- Marinho Daniel
- Marinho Sara
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Alda
- Marques Ana R
- Marques António
- Marques Catarina
- Marques Cristiana
- Marques Cristiana
- Marques Daniel R
- Marques Daniel R
- Marques Fátima M
- Marques Mariana
- Marques Mariana
- Marques Mariana
- Marques Mariana
- Marques Mª F
- Marques Mário
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Rita
- Marques Silvana F
- Marques Silvana F
- Marques Sílvia
- Marques Tatiana
- Marques-Rodrigues Alexandre
- Marques-Vieira Cristina
- Marquez Laura A
- Marsi Teresa O
- Marta-Simões Joana
- Marta-Simões Joana
- Marta-Simões Joana
- Marta-Simões Joana
- Martin Inmaculada Z
- Martinez-Hernandez Francisco
- Martinho Liliana
- Martins Ana R
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Anabela C
- Martins Carlos R
- Martins Cristina
- Martins Cristina
- Martins Emília
- Martins Emília
- Martins Emília
- Martins Eveliny S
- Martins Fernando
- Martins Fátima
- Martins Julian
- Martins Laura
- Martins Maria M
- Martins Matilde
- Martins Matilde
- Martins Patrícia
- Martins Raul
- Martins Rosa
- Martín Ignácio
- Marôco João
- Marôco João
- Mata Mª A
- Mata Mª A
- Mata Mª A
- Mateus Artur
- Mateus Artur
- Matheus Filipe
- Matos Ana R
- Matos Filomena
- Matos Maria
- Matos Rui
- Medeiros Anabela
- Medeiros Dayse C
- Medeiros-Garcia Lurdes
- Medina María S
- Meireles Alexandra
- Melo Elsa
- Melo Elsa
- Melo Elsa
- Melo Flávio
- Melo Rosa
- Melo Rosa
- Melo Rosa
- Melo Rosa
- Mendes Aida
- Mendes Ana
- Mendes Ana
- Mendes Ana
- Mendes Ana L
- Mendes Ana L
- Mendes Ana L
- Mendes Elenice
- Mendes F
- Mendes F.
- Mendes Felismina
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Fernando
- Mendes Francisco
- Mendes Francisco
- Mendes Francisco
- Mendes Isabel
- Mendes Isabel
- Mendes Joana
- Mendes Maria F
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Pedro
- Mendes Romeu
- Mendes Romeu
- Mendes Romeu
- Mendes Zaida
- Mendonça Carlos
- Mendonça Nuno
- Mendonça Paula
- Mendonça Paula
- Mendonça Verónica
- Mendonça Verónica
- Meneghetti Vanize
- Meneses Rui
- Menezes Ruth L
- Menino Eva
- Menino Eva
- Menino Eva
- Menino Eva
- Mercê Cristiana
- Mesquita Helena
- Mesquita Helena
- Mesquita João R
- Midões Cristiana
- Milanés Gemma M
- Minas Bárbara
- Minghelli Beatriz
- Minghelli Beatriz
- Miranda Cristiana
- Miranda Marta
- Miranda Natacha F
- Monago Fatima M
- Monago Fatima M
- Monago Fátima M
- Monago Rocio M
- Monteiro Diogo
- Monteiro Helena
- Monteiro Joana
- Monteiro Lina
- Monteiro Luís
- Monteiro M. J
- Monteiro M. J
- Monteiro Mª J
- Monteiro Sílvia
- Morais Carminda
- Morais Marina A
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Mª C
- Morais Nuno
- Moreira Eliana
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Fernando
- Moreira Isabel
- Moreira Liliana
- Moreira Liliana
- Moreira Rita L
- Moreno Ana L
- Morgado Alice
- Morgado Sónia
- Morgado Sónia
- Morna Clementina
- Morna Clementina
- Morouço Pedro
- Morouço Pedro
- Mota Maria
- Mota Maria
- Mota Priscilla
- Moura Cynthia B
- Moura-Ramos Mariana
- Mouroço Pedro
- Mourão Ricardo
- Mártires Alice
- Mónico Lisete
- Mónico Lisete
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Mónico Lisete M
- Nascimento Daniela
- Nascimento Maria S
- Nascimento V. B
- Natal Sônia
- Nave Filipe
- Nave Filipe
- Nazario Nazare
- Nazario Nazare
- Nazario Nazare
- Nazaré Cristina
- Nazário Nazaré O
- Neco Sofia
- Nelas Paula
- Neto João S
- Neves Carmo
- Neves Joana
- Neves Joel
- Neves Jéssica
- Neves Jéssica
- Neves Miguel
- Neves Sofia
- Neves Vanessa
- Nicola Paulo
- Nogueira Conceição
- Nogueira Paulo
- Nogueira Paulo
- Noné Ana
- Novais Sandra
- Novais Sandra
- Novais Sónia
- Novais Sónia
- Novo André
- Nugem Rita C
- Nugem Rita C
- Nunes Amélia
- Nunes Amélia F
- Nunes Carla
- Nunes Carla
- Nunes Carla
- Nunes Hélder
- Nunes Liliana
- Nunes S.
- Nuñez Cristina G
- Oliva Jefferson T
- Olivares Pedro R
- Oliveira Adriana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana I
- Oliveira Ana P
- Oliveira Anabela
- Oliveira Bibiana F
- Oliveira Bárbara
- Oliveira Camila A
- Oliveira Catarina
- Oliveira Denize C
- Oliveira Edmar S
- Oliveira Elizabete A
- Oliveira Emanuel
- Oliveira Eunice G
- Oliveira Eunice G
- Oliveira Isabel
- Oliveira Lara L
- Oliveira Manuel
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Michelle T
- Oliveira Mirna F
- Oliveira Raul
- Oliveira Rita
- Oliveira Rita
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Rita F
- Oliveira Sara
- Oliveira Sebastião T
- Oliveira Sebastião T
- Oliveira Suzete
- Oliveira Teresa C
- Oliveira Teresa T
- Oliveira Vânia P
- Olszewer Efrain O
- Ortiga Angela B
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Osório Nádia
- Pacheco José
- Padez Cristina
- Padilha José M
- Padilha José M
- Padilha José M
- Padilha José M
- Paixão S.
- Paixão Susana
- Paixão Susana
- Palmeira Lara
- Palmeira Lara
- Paraíso Nilson
- Paredes Hugo
- Parente Alexandra
- Parraça José A
- Parraça José A
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro
- Parreira Pedro D
- Parreira Pedro M
- Parreira Pedro M
- Parreira Pedro M
- Passadouro Rui
- Passadouro Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paulo Rui
- Paúl Constança
- Paúl Constança
- Paúl Constança
- Pedreiro Ana
- Pedro Ana R
- Pedro Ana R
- Pedro Luísa
- Pedrosa Dora
- Pedroso Rosa
- Peixoto Ermelindo
- Peixoto-Plácido Catarina
- Peralta Teresa
- Pereira A.
- Pereira Alexandre
- Pereira Alexandre
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana
- Pereira Ana M
- Pereira Ana M
- Pereira Ana M
- Pereira Ana T
- Pereira Ana T
- Pereira Anabela
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Carlos
- Pereira Cristina
- Pereira Elayne
- Pereira Elsa S
- Pereira Filipe
- Pereira Filomena
- Pereira Filomena
- Pereira Juliana
- Pereira Marta
- Pereira Olívia R
- Pereira Rafael
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Petrica João
- Pimenta Luís
- Pimenta Rui
- Pimentel Francisco
- Pimentel João
- Pimentel Rafaela
- Pinheiro Ana B
- Pinheiro Ana B
- Pinheiro Arminda A
- Pinheiro Patrícia C
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Cláudia
- Pinho Tânia
- Pinto Carlos
- Pinto Francisca
- Pinto Isabel C
- Pinto Isabel C
- Pinto J. L
- Pinto Joana
- Pinto M R
- Pinto Mª R
- Pinto Paulo F
- Pinto Sara
- Pinto Ítalo N
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pinto-Gouveia José
- Pires Filipa
- Pires Filipa
- Pires Tânia
- Pires Tânia
- Pisco Jacinta
- Pivetta Hedioneia F
- Piñero Ana S
- Poeta Susana
- Porta-Nova Rui
- Postolache Gabriela
- Postolache Octavian
- Poço Mariana
- Prado Alessandro
- Prata Ana R
- Prebianchi Helena
- Presado Mª H
- Preto Vera
- Príncipe Fernanda
- Pulido-Fuentes Montserrat
- Pérez-Caballero Francisco L
- Pérez-Caballero Francisco L
- Queirós Paulo
- Quelhas Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Querido Ana
- Quintana-Montesdeoca Mª P
- Quirino Diogo
- Rabiais Isabel
- Rafael Helga
- Rainho Conceição
- Rainho Conceição
- Rainho Conceição
- Rama Luís
- Rama Luís
- Rama Luís
- Ramalhete Cátia
- Ramalho André
- Ramalho André
- Ramalho Fátima
- Ramalho Sónia
- Ramalho Sónia
- Ramalho Sónia A
- Ramirez Francisco B
- Ramirez Francisco B
- Ramos Maurício R
- Raposo Vítor R
- Rei Ana C
- Reina Mercedes G
- Reis Alcinda C
- Reis Ana S
- Reis Arsénio
- Reis Cláudia
- Reis Laura
- Reis Victor M
- Reses Manoela
- Reuter Éboni M
- Ribas Patrícia
- Ribeiro Andrea
- Ribeiro Andrea
- Ribeiro Diana
- Ribeiro Fernando
- Ribeiro Jaime
- Ribeiro Jaime
- Ribeiro José C
- Ribeiro João
- Ribeiro Lígia C
- Ribeiro Maria
- Ribeiro Maria
- Ribeiro Maximiano
- Ribeiro Olivério
- Ribeiro Olivério
- Ribeiro Samila G
- Ribeiro Sandra
- Ribeiro Sandra
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro Óscar
- Ribeiro-Varandas Edna
- Richaud Sylvina
- Rocha C.
- Rocha Clara
- Rocha Clara
- Rocha Clara
- Rocha Mª C
- Rocha Mª C
- Rocha Saulo V
- Rocha Saulo V
- Rodrigo António
- Rodrigues Alexandre
- Rodrigues Alexandre
- Rodrigues Alexandrina
- Rodrigues António
- Rodrigues Cátia
- Rodrigues Diana
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rogério
- Rodrigues Rosa
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Sandra
- Rodrigues Teresa
- Rodrigues Vítor
- Rodrigues Vítor
- Rodriguez Cláudia K
- Rodriguez-De-Vera Bienvendida C
- Rodriguez-De-Vera Bienvenida
- Rodriguez-De-Vera Bienvenida C
- Rodríguez Ana B
- Rodríguez-De-Vera Bienvenida-Del-Carmen
- Rombo João
- Roque Fátima
- Rosa Manuel S
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Marlene C
- Rosa Roger S
- Rosa Roger S
- Rosado António
- Rosado António
- Rosário Rafaela
- Ruben Rui B
- Ruivo Joana
- Saavedra Francisco
- Saboga-Nunes Luís
- Saboga-Nunes Luís
- Sala José A
- Sala José A
- Sales Tiago
- Salgueiro Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salgueiro-Oliveira Anabela
- Salvador Mª C
- San-Martin Elisabete A
- Santana Miguel
- Santana Paula
- Santiago Conceição
- Santiago Eujcely C
- Santiago Eujcely C
- Santiago Luiz
- Santo Inês
- Santo Inês
- Santos Adriana
- Santos Ana
- Santos Bruno
- Santos Bruno
- Santos Erica
- Santos Flávia
- Santos Joana
- Santos Joana
- Santos Jorge
- Santos João
- Santos Leonino S
- Santos Luísa
- Santos Marina S
- Santos Marlene
- Santos Marlene
- Santos Nuno
- Santos Osvaldo
- Santos Osvaldo
- Santos Osvaldo
- Santos Rafael B
- Santos Rafael B
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos Sofia
- Santos-Rocha Rita
- Sardo Dolores
- Sardo Pedro
- Sardo Pedro
- Sarmento-Ribeiro Ana B
- Sarreira-Santos Alexandra
- Sarroeira Cassilda
- Schneider Dulcineia
- Schneider Dulcineia
- Schneiders Paloma B
- Schroeder Silvana S
- Schukg Susann
- Seabra André
- Seabra Daniel
- Seabra Daniel
- Seabra Paulo
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seixas Adérito
- Seiça Luís
- Seppänen Ulla-Maija
- Serapioni Mauro
- Serra Ana
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Serrano João
- Severino Sandy
- Siba Wafa A
- Silva Ana M
- Silva Ana M
- Silva Andrea G
- Silva André
- Silva Antónia
- Silva Armando
- Silva Carina
- Silva Carla R
- Silva Carlos
- Silva Carlos F
- Silva Catarina
- Silva Cláudia
- Silva Cláudia D
- Silva Daniel
- Silva Daniel
- Silva Darlen
- Silva David
- Silva Eduardo
- Silva Elsa
- Silva Ernestina
- Silva Helena R
- Silva Helena R
- Silva Iryna
- Silva Isabel
- Silva Joana
- Silva Joana
- Silva Joana
- Silva Luís D
- Silva Luís D
- Silva Maiza M
- Silva Manuel C
- Silva Margarida
- Silva Margarida
- Silva Maria A
- Silva Marilene
- Silva Marilene
- Silva Norberto
- Silva Paula
- Silva Paula A
- Silva Pedro
- Silva Pedro
- Silva Rafael
- Silva Rita
- Silva Rita
- Silva Rita P
- Silva Sara
- Silva Sara
- Silva Sara
- Silva Susana
- Silva Tatiane M
- Silva Vânia
- Silveira Paulo
- Sim-Sim Margarida
- Simões Alexandra
- Simões Cristina
- Simões João
- Simões Paulo C
- Simões Sónia
- Simões Ângela
- Siqueira Mariana S
- Siqueira Mariana S
- Soar Cláudia
- Soares Célia
- Soares Fátima
- Soares Fátima
- Soares Raquel
- Soares Salete
- Soares Sérgio
- Soares Valter
- Sousa Ana P
- Sousa Ana S
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Anderson R
- Sousa Carla
- Sousa Caroline R
- Sousa Cesar
- Sousa D.
- Sousa Diana
- Sousa Gilberta
- Sousa Gilberta
- Sousa Gracinda
- Sousa Jani
- Sousa Joana
- Sousa Joana
- Sousa Luís
- Sousa Marina
- Sousa Marina
- Sousa Nelson
- Sousa Nelson
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Patrícia
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Paulino
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Sousa Pedro
- Souza Clóvis A
- Souza Géssica M
- Souza Juliana A
- Souza Nelba R
- Souza Nelba R
- Spolaôr Newton
- Svensson Lola
- Sá Dayse
- Tapadas Rodrigo
- Tavares Aida I
- Tavares Ana
- Tavares Ana S
- Tavares José
- Tavares Mariline
- Tavares Nuno
- Teixeira A.
- Teixeira Ana
- Teixeira Ana
- Teixeira Ana M
- Teixeira Laetitia
- Teixo Ricardo
- Teles Patrícia
- Tena José M
- Tena Maria J
- Tenedório José A
- Tim-Tim Carolina
- Tomaz Jorge
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina
- Tomás Catarina C
- Tomás Teresa
- Topa Joana
- Torgal Jorge
- Torgal Jorge
- Torres Ana
- Torres Rui
- Trigo Africa P
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Trindade Inês A
- Tuna Ana R
- Tytgat Ite
- Uba-Chupel M.
- Uba-Chupel Mateus
- Ugalde Lierni U
- Ugartemendia Lierni
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Valado Ana
- Vale-Dias Luz
- Vale-Dias Maria L
- Valente Ana R
- Valente Carolina
- Valente Jorge
- Valente João
- Valim Frederico C
- Valim Frederico C
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Vaquinhas Marina
- Varandas Edna
- Vardasca Ricardo
- Vardasca Ricardo
- Vasconcelos Carlos
- Vasconcelos Carlos
- Vasconcelos Lélia R
- Vasconcelos Rita
- Vasconcelos Rita
- Vaz Daniela C
- Vaz Josiana A
- Vehreschild Viktor
- Vehreschild Viktor
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga Nélio
- Veiga-Branco Mª
- Velosa Fábia
- Veloso Milene
- Ventura David
- Ventura Maria
- Ventura Rita
- Ventura Sandra
- Vicente Corália
- Vicente Corália
- Vicente Corália
- Vicente Sara
- Vicente Sónia
- Vidal Eglidia F
- Viega-Branco Maria
- Vieira André
- Vieira Margarida
- Vieira Viviane L
- Vieitez Juan G
- Villanueva Ana G
- Vincha Kellem R
- Vinha Ana F
- Virgolino Ana
- Vizzotto Betina P
- Vélez Marta M
- Welter Aline
- Xavier Ana
- Xavier Ana
- Xavier Sandra
- Xavier Sandra
- Zilhão Adriano
- Publication venue
- Publication date
- 01/01/2004
- Field of study
As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved
A multi-country analysis of COVID-19 hospitalizations by vaccination status
- Author
- Aasmine Kaur
- Abby Hurd
- Abdulrahman Al-Fares
- Aditya John Anchan
- Adrian Streinu-Cercel
- Adrienne Chan
- Agostinho Monteiro
- Aidan Burrell
- Aisling Gavin
- Alan Hartman
- Aldo Rafael
- Alejandro Martín-Quiros
- Aleksander Rygh Holten
- Alessandra Notari
- Alexander J Mentzer
- Alexandros Cavayas
- Alexis F Turgeon
- Ali Ait Hssain
- Alina Kalicinska
- Alison M Meynert
- Alistair D Nichol
- Allison McGeer
- Amanda Corley
- Amna Faheem
- Ana da Silva Filipe
- Ana Freitas Ribeiro
- Ana Martins
- Anca Streinu-Cercel
- Anders Benjamin Kildal
- Anders Tveita
- Andra-Maris Post
- Andrea Angheben
- Andrea Cortegiani
- Andrea Kelly
- Andrea Rossanese
- Andrea Villoldo
- Andreas Lind
- Andrew Dagens
- Andrew Law
- Andrew Letizia
- Andy Law
- Angela Alberti
- Anika Atique
- Anjellica Chen
- Anna Beltrame
- Anne Margarita Dyrhol-Riise
- Anne McCarthy
- Anne-Marie Guerguerian
- Annemarie B Docherty
- Antonia Ho
- Antonia Ricchiuto
- Antonio Arcadipane
- António Mesquita
- Anuraj Shankar
- Argin G
- Asfia Sultana
- Asgar Rishu
- Atie Suwarti
- Audrey Dubot-Pérès
- Ayodhia Pitaloka
- Bailey Williams
- Bambang Pujo Semedi
- Baruch Joaquín
- Beathe Kiland Granerud
- Beatrice Alex
- Ben Morton
- Benjamin Bach
- Bernardo Ferreira
- Bernhard Roessler
- Bianca Boxma-de Klerk
- Birgitte Stiksrud
- Bisoffi Zeno
- Bounthavy Chaleunphon
- Bountoy Sibounheuang
- Brenda Reeve
- Brigid Flynn
- Cameron J Fairfield
- Caren Friedrich
- Carlos Cañada Illana
- Carlos Pimentel
- Caroline Kosgei
- Caroline Martins Rego
- Caroline Mudara
- Carrol Gamble
- Cassidy Codan
- Catarina Espírito Santo
- Catarina Pires
- Catherine A Shaw
- Catherine Blier
- Catherine Marquis
- Cecilia Canepa
- Ceila Maria Sant Ana Malaque
- Charlotte Summers
- Chiara Simona Cardellino
- Chiara Vitiello
- Chika Akwani
- Chloe Donohue
- Chris Kandel
- Chris McKay
- Christina Matthew
- Christl A Donnelly
- Christophe Fraser
- Christopher A Green
- Citarella Barbara Wanjiru
- Clare Jackson
- Clark D Russell
- Claudia Bianco
- Claudia Figueiredo-Mello
- Claudina Cruz
- Colin McArthur
- Cristina De Rose
- César Vieira
- Dag Henrik Reikvam
- Dan Meyer
- Dana Mustafa
- Daniel Haber
- Daniela Guerreiro
- Danilo Buonsenso
- Danoy Chommanam
- Dario Sinatti
- Dasgupta Abhishek
- Dave Nagpal
- David Bellemare
- David L Robertson
- David Maslove
- David S Y Ong
- David Stuart
- Dawn Higgins
- Debby Bogaert
- Decy Subekti
- Deepali Kumar
- Demetrios Kutsogiannis
- Denise Jaworsky
- Diana Póvoas
- Diego Franch-Llasat
- Diogo Borges
- Diogo Lopes
- Dounia Bouhmani
- Dr Rajesh Mohan Shetty
- Dwi Utomo Nusantara
- Eder Caceres
- Efstathia Mihelis
- Egle Saviciute
- Eka Airlangga
- Elisabetta Spinuzza
- Elizabeth A Ashley
- Ellen Shadowitz
- Else Quist-Paulsen
- Eman Al Qasim
- Emely Sanchez
- Emily Neumann
- Emma C Thomson
- Emmanuelle A Dankwa
- Emmanuelle Denis
- Esteban Garcia-Gallo
- Evert-Jan Wils
- Felwa Bin Humaid
- Ferran Roche-Campo
- Filipa Brás Monteiro
- Filipa Cardoso
- Filipe Cardoso
- Fiona Griffiths
- Frank Manetta
- Frank Olav Pettersen
- François Lamontagne
- François Martin Carrier
- Fredrik Müller
- Frédérick D'Aragon
- Gabriele Sales
- Gail Carson
- Gary Leeming
- Gary Schwartz
- Gayle Carney
- Gennaro Martucci
- Georgios Pollakis
- Geraldine Goco
- Gianluigi Li Bassi
- Giorgia Montrucchio
- Giovanna Occhipinti
- Giovanna Panarello
- Giulia Bertoli
- Giuseppe Foti
- Gloria Crowl
- Gonçalves Bronner P
- Graham S Cooke
- Gregory Purcell
- Gry Kloumann Bekken
- Gyan Sandhu
- Hamza Jaber
- Hannah Habraken
- Harrison Ewen M
- Hashmi Madiha
- Hayley Hardwick
- Heidi Dalton
- Heidi Gruner
- Hongru Ren
- Horby Peter
- Hubert Tessier-Grenier
- Hugo Inácio
- Husna Begum
- Iam Claire E Sarmiento
- Imrana Khalid
- Indrek Rätsep
- Ingrid G Bustos
- Isabela Saba
- ISARIC Clinical Characterisation Group: Sheryl Ann Abdukahil
- J Kevin Baird
- Jacky Y Suen
- Jake Dunning
- James Joshua Douglas
- James Lee
- James Scott-Brown
- Jan Cato Holter
- Janet Harrison
- Janet Liang
- Janet T Scott
- Janice Caoili
- Jaques Sztajnbok
- Jassat Waasila
- Jeff Powis
- Jeffrey Aliudin
- Jennifer Lee
- Jess Gibson
- Jessica Wittman
- Jia Wei
- Jimmy Ming-Yang Hsu
- Jo Dalton
- Joan Gómez-Junyent
- Joana Alves Cabrita
- Joana Cabrita
- Joana Ferrão
- John F Fraser
- John Kenneth Baillie
- John Marshall
- Jonathan Bitton
- Jorge Dantas
- Jorge Fernandes
- Jorge Paulos
- Joshua Solomon
- Josie Campisi
- José Casimiro
- José Ernesto Vidal
- José Ramalho
- Joy Ann Villanueva
- João Estevão
- João Teixeira
- Juan Pablo Horcajada
- Judit Villar
- Julia Garcia-Diaz
- Juliana Damas
- Justin Schaffer
- K Dhangar
- Kalynn Kennon
- Kamal Abu Jabal
- Karl Erik Müller
- Kartsonaki Christiana
- Katie O'Hearn
- Kenneth A McLean
- Kevin Katz
- Kraemer Moritz U G
- Kristian Tonby
- Kusum Menon
- Lana Almasri
- Lance C W Turtle
- Larissa Oliveira
- Lars Heggelund
- Latsaniphone Bountthasavong
- Laura Marsh
- Laveena Munshi
- Lefèvre Benjamin
- Leonardo Salazar
- Lina Morales Cely
- Linda Gail Skeie
- Lisa Norman
- Lisa Patterson
- Liv Hesstvedt
- Louise Sigfrid
- Luca Brazzi
- Lucia Moro
- Lucian Durham 3rd
- Luisa Quesada
- Lukas Arenz
- Lunn Miles
- Luís Val-Flores
- López Revilla José W
- Mahdad Noursadeghi
- Mahendra Singh
- Malcolm G Semple
- Mangala Narasimhan
- Manivanh Vongsouvath
- Maram Zahran
- Marc Csete
- Marco Giani
- Mare Pejkovska
- Margarite Grable
- Maria Amaral
- Maria Angelica Rivera Nuñez
- Maria de Piero
- Maria Zambon
- Mariachiara Ippolito
- Mariana Cascão
- Mariano Esperatti
- Marie Connor
- Marina Lanza
- Marina Wainstein
- Mark Downing
- Mark G Pritchard
- Marlene Santos
- Marta Alessi
- Marta Torre
- Martin-Loeches Ignacio
- Martina Escher
- Martina Hennessy
- Mary Copland
- Marília Andreia Fernandes
- Massimo Palmarini
- Mathew Thorpe
- Mathilde Duplaix
- Matteo Rossetti
- Matthew Hall
- Matthew Nelder
- Matthew Pellan Cheng
- Mayfong Mayxay
- Meera Chand
- Merson Laura
- Mical Paul
- Michael Edelstein
- Michael Schwameis
- Michael Varrone
- Michaela Barnikel
- Michele Petrovic
- Michelle E Kho
- Michelle Girvan
- Mo'nes Muhaisen
- Moad Atlowly
- Mohammed Alkahlout
- Moji Ghadimi
- Muge Cevik
- Murray Dryden
- Murray Wham
- Musharaf Sadat
- Mutia Rahardjani
- Mário Ferraz
- Nashat Abu Salah
- Nataly Farshait
- Nathaniel Christy
- Netta Beer
- Nicholas Yuri Barbosa
- Nick Daneman
- Nicole White
- Nidyanara Castanheira
- Nimisha Abdul Majeed
- Nina Buchtele
- Nora Fuentes
- Nuno Germano
- Oana Sandulescu
- Oleksa Rewa
- Olliaro Piero L
- Ooyanong Phonemixay
- Osama Aldabbourosama
- Paola Rodari
- Paolo Cattaneo
- Patricia Fontela
- Patricia Patricio
- Patrick Archambault
- Paul Klenerman
- Paula Custodio
- Pauline Yeung Ng
- Pawel Twardowski
- Pedro Faria
- Peter Daley
- Peter Kiiza
- Peter Openshaw
- Philippe Jouvet
- Phoebe Ampaw
- Phouvieng Douangdala
- Piero Valentini
- Piret Sillaots
- Piubelli Chiara
- Prasan Kumar Panda
- Prashant Nasa
- Praveen Kumar Ghisulal
- Rachael McConnochie
- Rachael Parke
- Rajavardhan Rangappa
- Rakesh Arora
- Raph L Hamers
- Renata Barbalho
- Reyes Luis Felipe
- Richard S Tedder
- Riinu Pius
- Rima Song
- Rita Alves
- Robert A Fowler
- Roberta Cavalin
- Rojek Amanda
- Rolando Claure-Del Granado
- Roman Ullrich
- Rosario Maria Torres Santos-Olmo
- Ross Hendry
- Rui Caetano Garcês
- Rui Garcês
- Rui Pereira
- Rupert Higgins
- Ruth Lyons
- Ryan S Thwaites
- Sadie Kelly
- Samantha Lissauer
- Samreen Ijaz
- Samuel Hinton
- Sanne Wesselius
- Sara Clohisey
- Sara Machado
- Sara Taleb
- Sarah E McDonald
- Sarah Moore
- Saye Khoo
- Scott Pharand
- Sergio Poli
- Seán Keating
- Shaher Hamdan
- Shaun Thompson
- Shiranee Sriskandan
- Shirin Tabrizi
- Shirley Sarfo-Mensah
- Shona C Moore
- Shrapnel Sally
- Silvia Castañeda
- Simon Forsyth
- Sofia Cardoso
- Sommay Keomany
- Sophie Halpin
- Soulichanya Phoutthavong
- Srinivas Murthy
- Stephanie Roberts
- Stephanie Yerkovich
- Stephanie-Susanne Stecher
- Stephen R Knight
- Steve Webb
- Sue Smith
- Sue Willems
- Summer Hamza
- Susanne Dudman
- Synne Jenum
- Teresa Lawrence
- Thipsavanh Bounphiengsy
- Thomas Drake
- Thomas Staudinger
- Thushan de Silva
- Tiago Isidoro
- Timothy M Uyeki
- Todd C Lee
- Tom Fletcher
- Tom Solomon
- Touxiong Yiaye
- Triona Downer
- Trude Steinsvik
- Tânia Sequeira
- Valeria Balan
- Valla Sahraei
- Vanessa Sancho-Shimizu
- Vegard Skogen
- Victoria Shaw
- Viladeth Praphasiri
- Virginie Williams
- Volkan Korten
- Wael Hafez
- Wai Ching Sin
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Yael Dishon
- Yaseen Arabi
- Yock Ping Chow
- Yousef Al-Saba'a
- Yusing Gu
- Zaina Dalloul
- Publication venue
- Publication date
- 12/09/2023
- Field of study
Background: Individuals vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), when infected, can still develop disease that requires hospitalization. It remains unclear whether these patients differ from hospitalized unvaccinated patients with regard to presentation, coexisting comorbidities, and outcomes. Methods: Here, we use data from an international consortium to study this question and assess whether differences between these groups are context specific. Data from 83,163 hospitalized COVID-19 patients (34,843 vaccinated, 48,320 unvaccinated) from 38 countries were analyzed. Findings: While typical symptoms were more often reported in unvaccinated patients, comorbidities, including some associated with worse prognosis in previous studies, were more common in vaccinated patients. Considerable between-country variation in both in-hospital fatality risk and vaccinated-versus-unvaccinated difference in this outcome was observed. Conclusions: These findings will inform allocation of healthcare resources in future surges as well as design of longer-term international studies to characterize changes in clinical profile of hospitalized COVID-19 patients related to vaccination history. Funding: This work was made possible by the UK Foreign, Commonwealth and Development Office and Wellcome (215091/Z/18/Z, 222410/Z/21/Z, 225288/Z/22/Z, and 220757/Z/20/Z); the Bill & Melinda Gates Foundation (OPP1209135); and the philanthropic support of the donors to the University of Oxford's COVID-19 Research Response Fund (0009109). Additional funders are listed in the "acknowledgments" section
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study
- Author
- Abbas Ali
- Abdukahil Sheryl Ann
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Absil Lara
- Acharya Subhash
- Acker Andrew
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Aryal Diptesh
- Asensio Angel
- Asif Namra
- Asim Mohammad
- Assie Jean Baptiste
- Atif Minahel
- Atique Anika
- Attanyake A. M. Udara Lakshan
- Auchabie Johann
- Auger Christelle Chantalat
- Aumaitre Hugues
- Auvet Adrien
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J. Kenneth
- Bak Erica
- Bakakos Agamemnon
- Bal Andriy
- Balan Valeria
- Balazote Pablo Serrano
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barclay Wendy S.
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bermúdez Juan Luis Cruz
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bissuel François
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brickell Kathy
- Brien Fionnuala O.
- Browne Alex
- Browne Shaunagh
- Brusse-Keizer Marjolein
- Buchtele Nina
- Buesaquillo Christian
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Camões João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castrillón Henry
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavayas Alexandros
- Ceccato Adrian
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chapplain Jean-Marc
- Chas Julie
- Chaudry Mobin
- Chen Anjellica
- Chen Yih-Sharng
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Cidade Jose Pedro
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Clohisey Sara
- Cobb Perren J.
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connor Marie
- Conrad Anne
- Contreras Sofía
- Conway Elaine
- Cooke Graham S.
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew J.
- Curley Ger
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- Cárcel Sheila
- da Silva Filipe Ana
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A.
- Dantas Jorge
- Darshana B. P. Sanka Ruwan Sri
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de la Calle Guillermo Maestro
- de Loughry Gillian
- de Mendoza Diego
- De Montmollin Etienne
- de Oliveira França Rafael Freitas
- de Pinho Oliveira Ana Isabel
- De Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Deacon Jillian
- Dean David
- Debard Alexa
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Dell’Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose
- Diaz Priscila
- Diaz Rodrigo
- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou Félix
- Docherty Annemarie B.
- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M.
- Donnelly Christl A.
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
- Douglas James Joshua
- Dournon Nathalie
- Dow Denisse Bazan
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Dudman Susanne
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Duque Sara
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- D’Aragon Frédérick
- D’Ortenzio Eric
- Echeverria-Villalobos Marco
- Egan Siobhan
- Eira Carla
- Elapavaluru Subbarao
- Elharrar Brigitte
- Ellerbroek Jacobien
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Endo Tomoyuki
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Escher Martina
- Esperatti Mariano
- Esperou Hélène
- Esposito-Farese Marina
- Estevão João
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J.
- Fakar Zul
- Fareed Komal
- Faria Pedro
- Farooq Ahmed
- Fatoni Arie Zainul
- Faure Karine
- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
- Feeney Laura
- Fernandes Jorge
- Fernandes Marília Andreia
- Fernandes Susana
- Ferrand François-Xavier
- Ferraz Mário
- Ferreira Benigno
- Ferreira Bernardo
- Ferreira Isabel
- Ferreira Sílvia
- Ferrer-Roca Ricard
- Ferriere Nicolas
- Ferrão Joana
- Ficko Céline
- Figueiredo-Mello Claudia
- Fiorda Juan
- Flament Thomas
- Flateau Clara
- Fletcher Tom
- Florio Letizia Lucia
- Flynn Deirdre
- Foley Claire
- Foley Jean
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Tatiana
- Fontela Patricia
- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A.
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John F.
- Freire Marcela Vieira
- French Craig
- Friedrich Caren
- Fry Stéphanie
- Fuentes Nora
- Fuentes Yuli V.
- Fukuda Masahiro
- G Argin
- Gaborieau Valérie
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- Gaião Sérgio
- Gallagher Phil
- Gamble Carrol
- Gandonniere Charlotte Salmon
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- Garcês Rui Caetano
- García Ruth N. Jorge
- Garimella Navya
- Garot Denis
- Garrait Valérie
- Gauli Basanta
- Gault Nathalie
- Gavin Aisling
- Gavrylov Anatoliy
- Gaymard Alexandre
- Gebauer Johannes
- Geraud Eva
- Germano Nuno
- Ghosn Jade
- Giani Marco
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Gilroy Elaine
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Glikman Daniel
- Glybochko Petr
- Gnall Eric
- Goco Geraldine
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Golob Jonathan
- Gominet Marie
- Gonzalez Alicia
- González Víctor Quirós
- Gonçalves Bronner P.
- Gordon Patricia
- Gorenne Isabelle
- Goubert Laure
- Goujard Cécile
- Goulenok Tiphaine
- Grable Margarite
- Graf Jeronimo
- Grandin Edward Wilson
- Granerud Beathe Kiland
- Granier Pascal
- Grasselli Giacomo
- Green Christopher A.
- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
- Griffee Matthew
- Griffiths Fiona
- Groenendijk Albert
- Gruner Heidi
- Gu Yusing
- Guedj Jérémie
- Guego Martin
- Guellec Dewi
- Guerguerian Anne-Marie
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimard Thomas
- Gómez-Junyent Joan
- Haalboom Marieke
- Haber Daniel
- Habraken Hannah
- Hachemi Ali
- Hadri Nadir
- Haidri Fakhir
- Hakak Sheeba
- Hall Adam
- Hall Matthew
- Halpin Sophie
- Hameed Jawad
- Hamer Ansley
- Hamidfar Rebecca
- Hammond Terese
- Haniffa Rashan
- Hardwick Hayley
- Harrison Ewen M.
- Harrison Janet
- Harrison Samuel Bernard Ekow
- Hasan Mohd Shahnaz
- Hashmi Junaid
- Hashmi Madiha
- Hayat Muhammad
- Hayes Ailbhe
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Hendry Ross
- Hennessy Martina
- Hentzien Maxime
- Herreros José Miguel Cisneros
- Hershey Andrew
- Hesstvedt Liv
- Hidayah Astarini
- Higgins Dawn
- Higgins Eibhilin
- Higgins Rupert
- Hinchion Rita
- Hinton Samuel
- Hitoto Hikombo
- Ho Antonia
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holter Jan Cato
- Horby Peter
- Horcajada Juan Pablo
- Hoshino Koji
- Hoshino Kota
- Houas Ikram
- Hough Catherine L.
- Hssain Ali Ait
- Hsu Jimmy Ming-Yang
- Hulot Jean-Sébastien
- Humaid Felwa Bin
- Huo Stella
- Hurd Abby
- Hussain Iqbal
- Ibáñez-Prada Elsa D.
- Ijaz Samreen
- Ikram Arfan
- Illes Hajnal-Gabriela
- Imbert Patrick
- Imran Mohammad
- Imtiaz Aftab
- Inácio Hugo
- Ippolito Mariachiara
- Isgett Sarah
- Isidoro Tiago
- Isnard Margaux
- Ivulich Daniel
- Iñiguez Jonathan Samuel Chávez
- Jaafar Danielle
- Jaafoura Salma
- Jabot Julien
- Jackson Clare
- Jamieson Nina
- Jaquet Pierre
- Jaud-Fischer Coline
- Jaureguiberry Stéphane
- Jego Florence
- Jenum Synne
- Jiménez Miguel Pedrera
- Joseph Cédric
- Joseph Mark
- Joshi Swosti
- Jourdain Mercé
- Jouvet Philippe
- Jung Anna
- Juzar Dafsah
- Kafif Ouifiya
- Kaguelidou Florentia
- Kali Sabina
- Kalomoiri Smaragdi
- Kandamby Darshana Hewa
- Kandel Chris
- Kanwal Darakhshan
- Kartsonaki Christiana
- Kataria Anant
- Katz Kevin
- Kay Christy
- Keane Hannah
- Keating Seán
- Kelly Andrea
- Kelly Aoife
- Kelly Claire
- Kelly Niamh
- Kelly Sadie
- Kelly Yvelynne
- Kelsey Maeve
- Kennon Kalynn
- Kernan Maeve
- Kerroumi Younes
- Keshav Sharma
- Khalid Imrana
- Khalid Osama
- Khalil Antoine
- Khan Coralie
- Khan Irfan
- Khan Quratul Ain
- Khan Rashid Nasim
- Khanal Sushil
- Khatak Abid
- Khawaja Amin
- Kho Michelle E.
- Khoo Saye
- Khoso Nasir
- Kida Yuri
- Kiiza Peter
- Kildal Anders Benjamin
- Kimmoun Antoine
- Kindgen-Milles Detlef
- Kitamura Nobuya
- Klenerman Paul
- Klont Rob
- Knight Stephen R.
- Kobbe Robin
- Kodippily Chamira
- Koirala Sabin
- Kosgei Caroline
- Kpangon Arsène
- Krawczyk Karolina
- Kruglova Oksana
- Kumar Deepali
- Kumar Mukesh
- Kuriakose Dinesh
- Kurtzman Ethan
- Kutsogiannis Demetrios
- Kutsyna Galyna
- Kyriakoulis Konstantinos
- Lachatre Marie
- Lacoste Marie
- Laffey John G.
- Lagrange Marie
- Laine Fabrice
- Lairez Olivier
- Lakhey Sanjay
- Lalueza Antonio
- Lambert Marc
- Lamontagne François
- Langelot-Richard Marie
- Langlois Vincent
- Lantang Eka Yudha
- Lanza Marina
- Laouénan Cédric
- Laribi Samira
- Lariviere Delphine
- Lasry Stéphane
- Latif Naveed
- Launay Odile
- Laureillard Didier
- Lavie-Badie Yoan
- Law Andrew
- Lawrence Cassie
- Lawrence Teresa
- Le Bihan Clément
- Le Bris Cyril
- Le Falher Georges
- Le Fevre Lucie
- Le Hingrat Quentin
- Le Maréchal Marion
- Le Mestre Soizic
- Le Moal Gwenaël
- Le Moing Vincent
- Le Nagard Hervé
- Le Turnier Paul
- Le Minh
- Leal Ema
- Leathlobhair Niamh Ni
- Lee James
- Lee Jennifer
- Lee Su Hwan
- Lee Todd C.
- Leeming Gary
- Lefebvre Bénédicte
- Lefebvre Laurent
- Lefèvre Benjamin
- LeGac Sylvie
- Lelievre Jean-Daniel
- Lellouche François
- Lemaignen Adrien
- Lemee Véronique
- Lemeur Anthony
- Lemmink Gretchen
- Lennon Jenny
- Leone Marc
- Leone Michela
- Lescure François-Xavier
- Lesens Olivier
- Lesouhaitier Mathieu
- Lester-Grant Amy
- Levy Bruno
- Levy Yves
- Levy-Marchal Claire
- Lewandowska Katarzyna
- León Rafael
- Liaquat Ali
- Liegeon Geoffrey
- Lim Wei Shen
- Lima Chantre
- Lina Bruno
- Lind Andreas
- Lingas Guillaume
- Lion-Daolio Sylvie
- Liu Keibun
- Livrozet Marine
- Lizotte Patricia
- Loforte Antonio
- Lolong Navy
- Lopes Diogo
- Lordemann Anja Grosse
- Loschner Anthony L.
- Loubet Paul
- Loufti Bouchra
- Louis Guillame
- Lourenco Silvia
- Lovelace-Macon Lara
- Lowik Marije
- Lucet Jean Christophe
- Luna Carlos M.
- Luong Liem
- Luque Nestor
- Luton Dominique
- Lwin Nilar
- Lyons Ruth
- L’Her Erwan
- Maasikas Olavi
- Mabiala Oryane
- Machado Moïse
- Machado Sara
- Macheda Gabriel
- Madiha Hashmi
- Mahieu Rafael
- Mahy Sophie
- Maia Ana Raquel
- Maier Lars S.
- Maillet Mylène
- Maitre Thomas
- Malaque Ana
- Malfertheiner Maximilian
- Malik Nadia
- Mallon Paddy
- Maltez Fernando
- Malvy Denis
- Manda Victoria
- Mandelbrot Laurent
- Mankikian Julie
- Manning Edmund
- Manuel Aldric
- Marino Daniel
- Marino Flávio
- Markowicz Samuel
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- Postma Douwe F.
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- Preiser Jean-Charles
- Prinssen Anton
- Pritchard Mark G.
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- Tagherset Lysa
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- Teixeira João
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- Thill Benoît
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tissot Noémie
- Toki Maria
- Tonby Kristian
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- Tubiana Sarah
- Tuite Helen
- Turmel Jean-Marie
- Turtle Lance C. W.
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Udayanga P. G. Ishara
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- Van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
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- van Netten Carolien
- van Veen Ilonka
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- Vanoverschelde Henk
- Varghese Pooja
- Vasconcelos Malte Kohns
- Vauchy Charline
- Vecham Pavan Kumar
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vickers James
- Vidal José Ernesto
- Vieira César
- Vijayan Deepak
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Suzette
- Williams Virginie
- Wils Evert-Jan
- Wong Calvin
- Xynogalas Ioannis
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yerkovich Stephanie
- Yiu Ng Wing
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zahran Maram
- Zambon Maria
- Zanella Alberto
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 13/09/2022
- Field of study
Background: Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs).
Methods: This is a multinational, multicentre, prospective cohort study embedded in the ISARIC-WHO COVID-19 Clinical Characterisation Protocol. Patients with laboratory-confirmed SARS-CoV-2 infection who required hospital admission were recruited prospectively. Patients treated with HFNC, NIV, or IMV within the first 24 h of hospital admission were included in this study. Descriptive statistics, random forest, and logistic regression analyses were used to describe clinical characteristics and compare clinical outcomes among patients treated with the different types of advanced respiratory support.
Results: A total of 66,565 patients were included in this study. Overall, 82.6% of patients were treated in HIC, and 40.6% were admitted to the hospital during the first pandemic wave. During the first 24 h after hospital admission, patients in HICs were more frequently treated with HFNC (48.0%), followed by NIV (38.6%) and IMV (13.4%). In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HIC and 28.8% from LMIC. The variables most strongly associated with non-invasive ventilation failure, defined as progression to IMV, were high leukocyte counts at hospital admission (OR [95%CI]; 5.86 [4.83-7.10]), treatment in an LMIC (OR [95%CI]; 2.04 [1.97-2.11]), and tachypnoea at hospital admission (OR [95%CI]; 1.16 [1.14-1.18]). Patients who failed HFNC/NIV had a higher 28-day fatality ratio (OR [95%CI]; 1.27 [1.25-1.30]).
Conclusions: In the present international cohort, the most frequently used advanced respiratory support was the HFNC. However, IMV was used more often in LMIC. Higher leucocyte count, tachypnoea, and treatment in LMIC were risk factors for HFNC/NIV failure. HFNC/NIV failure was related to worse clinical outcomes, such as 28-day mortality. Trial registration This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- Abellán Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Özlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia González
- Aleem Muhammad
- Alegre Inês
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz Amorós
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-Díez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
- Amado Fabíola
- Amador Cristina García
- Amanullah Nazli
- Amaral Hélida Aline Tomacheski
- Amaral Luis
- Amin-Tai Hizami
- Aminu Bashiru
- Amir Ahmad Suhaimi
- Ammar Ahmed Siddique
- Ammar Mona Ahmed
- Ammendola Michele
- Ammerata Giorgio
- Amorim Edgar
- Ancans Guntis
- Anderson Tom
- Andrade Diogo
- Andrejevic Predrag
- Andrés Beatriz Díaz San
- Anestiadou Elissavet
- Ang Chin Wee
- Angelo Franceschi
- Anokhin Evgeny
- Anoldo Pietro
- Antakia Ramez
- Anton Majd
- Antonelli Serena
- Antropoli Carmine
- Anula Rocio
- Anwar Jamal
- Anyadike Florence
- Apostolakidou Magda
- Apostolidi Eirini
- Aprea Giovanni
- Arabadzhiev Angel
- Arakawa Satoshi
- Arauz Jazmin
- Aravindan U
- Aremu Abdurrahman
- Aremu Isiaka
- Argawy Osama
- Arican Can
- Arida Zahed Abu
- Armellin Claudia
- Arnaoutoglou Eleni
- Arreguy-Borges Kanthya
- Artigot Mariano
- Arturi Alessandro
- Arulappan Nirupama
- Arya Shobhit
- Arynov Ardak
- Asaad Peter
- Asano Yukio
- Ascari Francesca
- Asgarov Mohsum
- Ashmawy Soad
- Aslam Muhammad Imran
- Assimakopoulou Elena
- Assis Ana
- Astilleta Romina
- Atanasov Boyko
- Atendido Tiffany
- Athanasakis Elias
- Atici Semra Demirli
- Avellaneda Nicholas
- Avellaneda Nicolas
- Avseren Goksu
- Awead Marwa
- Ayandipo Omobolaji
- Aybar Engin
- Aydin Funda
- Aydin Gaye
- Ayoub Kusay
- Aytac Erman
- Aytaç Erman
- Azevedo Jose
- Azevedo Patricia
- Azhar Najia
- Aziz Gowhar
- Azman Zairul Azwan Mohd
- Aşkar Ahmet
- Babatunde Olanrewaju
- Badawi Marwa
- Baek Jeong-Heum
- Baez Noelia Fernández
- Baeza-Murcia Melody
- Bagnardi Francesco
- Baharom Salahudin
- Baik Seung Hyuk
- Baimakhanov Abylai
- Bains Lovenish
- Baker Aleksandra
- Bakmaz Bernarda
- Bala Abubakar Muhammad
- Balaban Vladimir
- Balalis Dimitrios
- Balasubramaniam Dinesh
- Balathayalan Yathev
- Baldi Claudio
- Balestri Riccardo
- Balfour James
- Ballah Abubakar
- Ballian Nikiforos
- Balooshi Iman Al
- Baloyiannis Ioannis
- Bamford Richard
- Bandar Mahdi Al
- Banham Gail
- Bannoud Mohammad Hassan
- Baptista Victor
- Baral Jörg
- Barbalace Nicolas
- Barbato Giuseppe
- Barbosa Anderson
- Bareka Metaxia
- Baris Baver
- Barradas Renato
- Barreda Sara Castillo
- Barrena-Blazquez Silvestra
- Barton Jess
- Bartosiak Katarzyna
- Bashilkina Olga
- Bashir Mohammed
- Basile Raffaele
- Basnyat Pradeep
- Batool Sana
- Bautista Wilson Manuel Sánchez
- Bayhan Zülfü
- Bayo José Manuel Muros
- Bayón Raquel Álvaro
- Baños Pedro Antonio Parra
- Beard David
- Bedzhanyan Arkady
- Behilil Chakib
- Bekele Kebebe
- Belarmino Armin
- Belay Million
- Belev Nikolay
- Bellato Vittoria
- Beltrán de Heredia Juan
- Belvedere Angela
- Benetti Emilio
- Benetti Sara
- Bengueddach Aicha
- Benjelloun El Bachir
- Benkabbou Amine
- Bennett James
- Bensafir Salim
- Bergamini Carlo
- Bernotaite Vlada
- Beron Reinaldo Isaacs
- Bethune Robert
- Bezede Cosmin
- Beznosenko Andriy
- Bhangu Aneel
- Bhargava Aman
- Bhat Rama Rani Krishna
- Bianchi Romina
- Bianco Francesco
- Bigoni Irene
- Binetti Margherita
- Bintintan Vasile
- Biondi Alberto
- Biondo Santino Antonio
- Bisgin Tayfun
- Bisheet George
- Bissett Ian
- Biswas Jyotirmoy
- Blackwell Sue
- Blanco Pablo
- Blanco Raquel Ríos
- Blanco-Colino Ruth
- Blasco Laura Fraile
- Blazquez-Martin Alma
- Bobadilla Billy Jimenez
- Bocancia Raluca
- Boccia Giuseppe
- Bogatikov Alexander
- Bolanle Olajide Edward
- Bomfa-Barbosa Alysson
- Bompou Effrosyni
- Bonardello Michela
- Bonci Eduard-Alexandru
- Bordom Daniel Osei
- Borges Filipe
- Borghi Felice
- Boschiero Matheus Negri
- Bose Bodhisattva
- Bouchagier Konstantinos
- Boudjenan-Serradj Nabil
- Boudoux Sabrina
- Bourazani Maria
- Boyce Stephen
- Bozbiyik Osman
- Bracale Umberto
- Brachini Gioia
- Bradulskis Saulius
- Brainsa Eneida
- Brandström Gustav
- Braumille Markus
- Bravo Ana Minaya
- Bravo Raquel
- Bredikhin Mikhail
- Brito Noelia
- Bruni Andrea
- Buccianti Piero
- Buchs Nicolas
- Buchwald Pamela
- Budnikova Ina
- Budrikienė Rima
- Buey Lourdes
- Buijs Louis
- Buleje Jorge Alejandro Benavides
- Burlov Nikita
- Butt Anam
- Byshetty Rajendar
- Bywater Edward
- Bzikha Ilham
- Bánky Balázs
- Bælum Jens Kristian
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- Yilmazlar Tuncay
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- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- Zadrożna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
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- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah Kağan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Álvarez-Llano Laura
- Ângelo Miguel Duarte
- ÓSullivan Sara Nuñez
- Özçelik Mehmet Faik
- Ćoza Ivo
- Şanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective, multinational, observational study
- Author
- Abbas Ali
- Abdukahil Sheryl Ann
- Abe Ryuzo
- Abel Laurent
- Abreu Julia Rodriguez
- Absil Lara
- Acharya Subhash
- Acker Andrew
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alegesan Senthilkumar
- Alegre Cynthia
- Alessi Marta
- Alex Beatrice
- Alexandre K. vin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Altaf Aneela
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart S. verine
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Argin G.
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Asif Namra
- Asim Mohammad
- Assie Jean Baptiste
- Atif Minahel
- Atique Anika
- Attanyake A. M. Udara Lakshan
- Auchabie Johann
- Auger Christelle Chantalat
- Aumaitre Hugues
- Auvet Adrien
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J. Kenneth
- Bak Erica
- Bakakos Agamemnon
- Bal Andriy
- Balan Valeria
- Balazote Pablo Serrano
- Banheiro Bruno Sarmento
- Bani-Sadr Firouzé
- Barbalho Renata
- Barclay Wendy S.
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beluze Marine
- Benech Nicolas
- Benkerrou Dehbia
- Bennett Suzanne
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bermúdez Juan Luis Cruz
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bissuel François
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-H. lène
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller K. vin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brickell Kathy
- Brien Fionnuala O.
- Browne Alex
- Browne Shaunagh
- Brusse-Keizer Marjolein
- Buchtele Nina
- Buesaquillo Christian
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Camões João
- Canepa Cecilia
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castrillón Henry
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavalli Giulio Giovanni
- Cavayas Alexandros
- Ceccato Adrian
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chapplain Jean-Marc
- Chas Julie
- Chaudry Mobin
- Chen Anjellica
- Chen Yih-Sharng
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Cidade Jose Pedro
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Clohisey Sara
- Cobb Perren J.
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connor Marie
- Conrad Anne
- Contreras Sofía
- Conway Elaine
- Cooke Graham S.
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew J.
- Curley Ger
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- Cárcel Sheila
- da Silva Filipe Ana
- da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A.
- Dantas Jorge
- Darshana B. P. Sanka Ruwan Sri
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de la Calle Guillermo Maestro
- de Loughry Gillian
- de Mendoza Diego
- de Montmollin Etienne
- de Oliveira França Rafael Freitas
- de Pinho Oliveira Ana Isabel
- de Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Deacon Jillian
- Dean David
- Debard Alexa
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Dell’Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Dias André
- Diaz Juan Jose
- Diaz Priscila
- Diaz Rodrigo
- Didier K. vin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet J. rôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou F. lix
- Docherty Annemarie B.
- Doherty Helen
- Dominguez Carmen Infante
- Dondorp Arjen M.
- Donnelly Christl A.
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival C. line
- Douglas James Joshua
- Dournon Nathalie
- Dow Denisse Bazan
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Dudman Susanne
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Duque Sara
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- D’Aragon Frédérick
- D’Ortenzio Eric
- Echeverria-Villalobos Marco
- Egan Siobhan
- Eira Carla
- Elapavaluru Subbarao
- Elharrar Brigitte
- Ellerbroek Jacobien
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Endo Tomoyuki
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Escher Martina
- Esperatti Mariano
- Esperou H. lène
- Esposito-Farese Marina
- Estevão João
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J.
- Fakar Zul
- Fareed Komal
- Faria Pedro
- Farooq Ahmed
- Fatoni Arie Zainul
- Faure Karine
- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
- Feeney Laura
- Fernandes Jorge
- Fernandes Marília Andreia
- Fernandes Susana
- Ferrand François-Xavier
- Ferraz M. rio
- Ferreira Benigno
- Ferreira Bernardo
- Ferreira Isabel
- Ferreira S. lvia
- Ferrer-Roca Ricard
- Ferriere Nicolas
- Ferrão Joana
- Ficko C. line
- Figueiredo-Mello Claudia
- Fiorda Juan
- Flament Thomas
- Flateau Clara
- Fletcher Tom
- Florio Letizia Lucia
- Flynn Deirdre
- Foley Claire
- Foley Jean
- Fomin Victor
- Fonseca Claudio Duarte
- Fonseca Tatiana
- Fontela Patricia
- Forsyth Simon
- Foster Denise
- Foti Giuseppe
- Fourn Erwan
- Fowler Robert A.
- Fraher Marianne
- Franch-Llasat Diego
- Fraser Christophe
- Fraser John F.
- Freire Marcela Vieira
- French Craig
- Friedrich Caren
- Fry Stéphanie
- Fuentes Nora
- Fuentes Yuli V.
- Fukuda Masahiro
- Gaborieau Valérie
- Gaci Rostane
- Gagliardi Massimo
- Gagnard Jean-Charles
- Gagneux-Brunon Amandine
- Gaião S. rgio
- Gallagher Phil
- Gamble Carrol
- Gandonniere Charlotte Salmon
- Garan Arthur
- Garcia Rebekha
- Garcia-Gallo Esteban
- Garcês Rui Caetano
- García Ruth N. Jorge
- Garimella Navya
- Garot Denis
- Garrait Valérie
- Gauli Basanta
- Gault Nathalie
- Gavin Aisling
- Gavrylov Anatoliy
- Gaymard Alexandre
- Gebauer Johannes
- Geraud Eva
- Germano Nuno
- Ghosn Jade
- Giani Marco
- Gibson Jess
- Gigante Tristan
- Gilg Morgane
- Gilroy Elaine
- Giordano Guillermo
- Girvan Michelle
- Gissot Valérie
- Glikman Daniel
- Glybochko Petr
- Gnall Eric
- Goco Geraldine
- Goehringer François
- Goepel Siri
- Goffard Jean-Christophe
- Golob Jonathan
- Gominet Marie
- Gonzalez Alicia
- González V. ctor Quirós
- Gonçalves Bronner P.
- Gordon Patricia
- Gorenne Isabelle
- Goubert Laure
- Goujard C. cile
- Goulenok Tiphaine
- Grable Margarite
- Graf Jeronimo
- Grandin Edward Wilson
- Granerud Beathe Kiland
- Granier Pascal
- Grasselli Giacomo
- Green Christopher A.
- Greene Courtney
- Greenhalf William
- Greffe Segolène
- Grieco Domenico Luca
- Griffee Matthew
- Griffiths Fiona
- Groenendijk Albert
- Gruner Heidi
- Gu Yusing
- Guedj J. rémie
- Guego Martin
- Guellec Dewi
- Guerguerian Anne-Marie
- Guerreiro Daniela
- Guery Romain
- Guillaumot Anne
- Guilleminault Laurent
- Guimard Thomas
- Gómez-Junyent Joan
- Haalboom Marieke
- Haber Daniel
- Habraken Hannah
- Hachemi Ali
- Hadri Nadir
- Haidri Fakhir
- Hakak Sheeba
- Hall Adam
- Hall Matthew
- Halpin Sophie
- Hameed Jawad
- Hamer Ansley
- Hamidfar Rebecca
- Hammond Terese
- Haniffa Rashan
- Hardwick Hayley
- Harrison Ewen M.
- Harrison Janet
- Harrison Samuel Bernard Ekow
- Hasan Mohd Shahnaz
- Hashmi Junaid
- Hashmi Madiha
- Hayat Muhammad
- Hayes Ailbhe
- Hays Leanne
- Heerman Jan
- Heggelund Lars
- Hendry Ross
- Hennessy Martina
- Hentzien Maxime
- Herreros José Miguel Cisneros
- Hershey Andrew
- Hesstvedt Liv
- Hidayah Astarini
- Higgins Dawn
- Higgins Eibhilin
- Higgins Rupert
- Hinchion Rita
- Hinton Samuel
- Hitoto Hikombo
- Ho Antonia
- Hoctin Alexandre
- Hoffmann Isabelle
- Hoiting Oscar
- Holt Rebecca
- Holten Aleksander Rygh
- Holter Jan Cato
- Horby Peter
- Horcajada Juan Pablo
- Hoshino Koji
- Hoshino Kota
- Houas Ikram
- Hough Catherine L.
- Hssain Ali Ait
- Hsu Jimmy Ming-Yang
- Hulot Jean-S. bastien
- Humaid Felwa Bin
- Huo Stella
- Hurd Abby
- Hussain Iqbal
- Ibáñez-Prada Elsa D.
- Ijaz Samreen
- Ikram Arfan
- Illes Hajnal-Gabriela
- Imbert Patrick
- Imran Mohammad
- Imtiaz Aftab
- Inácio Hugo
- Ippolito Mariachiara
- Isgett Sarah
- Isidoro Tiago
- Isnard Margaux
- Ivulich Daniel
- Iñiguez Jonathan Samuel Chávez
- Jaafar Danielle
- Jaafoura Salma
- Jabot Julien
- Jackson Clare
- Jamieson Nina
- Jaquet Pierre
- Jaud-Fischer Coline
- Jaureguiberry Stéphane
- Jego Florence
- Jenum Synne
- Jiménez Miguel Pedrera
- Joseph C. dric
- Joseph Mark
- Joshi Swosti
- Jourdain Mercé
- Jouvet Philippe
- Jung Anna
- Juzar Dafsah
- Kafif Ouifiya
- Kaguelidou Florentia
- Kali Sabina
- Kalomoiri Smaragdi
- Kandamby Darshana Hewa
- Kandel Chris
- Kanwal Darakhshan
- Kartsonaki Christiana
- Kataria Anant
- Katz Kevin
- Kay Christy
- Keane Hannah
- Keating Seán
- Kelly Andrea
- Kelly Aoife
- Kelly Claire
- Kelly Niamh
- Kelly Sadie
- Kelly Yvelynne
- Kelsey Maeve
- Kennon Kalynn
- Kernan Maeve
- Kerroumi Younes
- Keshav Sharma
- Khalid Imrana
- Khalid Osama
- Khalil Antoine
- Khan Coralie
- Khan Irfan
- Khan Quratul Ain
- Khan Rashid Nasim
- Khanal Sushil
- Khatak Abid
- Khawaja Amin
- Kho Michelle E.
- Khoo Saye
- Khoso Nasir
- Kida Yuri
- Kiiza Peter
- Kildal Anders Benjamin
- Kimmoun Antoine
- Kindgen-Milles Detlef
- Kitamura Nobuya
- Klenerman Paul
- Klont Rob
- Knight Stephen R.
- Kobbe Robin
- Kodippily Chamira
- Koirala Sabin
- Kosgei Caroline
- Kpangon Arsène
- Krawczyk Karolina
- Kruglova Oksana
- Kumar Deepali
- Kumar Mukesh
- Kuriakose Dinesh
- Kurtzman Ethan
- Kutsogiannis Demetrios
- Kutsyna Galyna
- Kyriakoulis Konstantinos
- Lachatre Marie
- Lacoste Marie
- Laffey John G.
- Lagrange Marie
- Laine Fabrice
- Lairez Olivier
- Lakhey Sanjay
- Lalueza Antonio
- Lambert Marc
- Lamontagne François
- Langelot-Richard Marie
- Langlois Vincent
- Lantang Eka Yudha
- Lanza Marina
- Laouénan C. dric
- Laribi Samira
- Lariviere Delphine
- Lasry Stéphane
- Latif Naveed
- Launay Odile
- Laureillard Didier
- Lavie-Badie Yoan
- Law Andrew
- Lawrence Cassie
- Lawrence Teresa
- le Bihan Clément
- le Bris Cyril
- le Falher Georges
- le Fevre Lucie
- le Hingrat Quentin
- le Maréchal Marion
- le Mestre Soizic
- le Moal Gwenaël
- le Moing Vincent
- le Nagard Hervé
- le Turnier Paul
- le Minh
- Leal Ema
- Leathlobhair Niamh Ni
- Lee James
- Lee Jennifer
- Lee Su Hwan
- Lee Todd C.
- Leeming Gary
- Lefebvre B. nédicte
- Lefebvre Laurent
- Lefèvre Benjamin
- LeGac Sylvie
- Lelievre Jean-Daniel
- Lellouche François
- Lemaignen Adrien
- Lemee V. ronique
- Lemeur Anthony
- Lemmink Gretchen
- Lennon Jenny
- Leone Marc
- Leone Michela
- Lescure François-Xavier
- Lesens Olivier
- Lesouhaitier Mathieu
- Lester-Grant Amy
- Levy Bruno
- Levy Yves
- Levy-Marchal Claire
- Lewandowska Katarzyna
- León Rafael
- Liaquat Ali
- Liegeon Geoffrey
- Lim Wei Shen
- Lima Chantre
- Lina Bruno
- Lind Andreas
- Lingas Guillaume
- Lion-Daolio Sylvie
- Liu Keibun
- Livrozet Marine
- Lizotte Patricia
- Loforte Antonio
- Lolong Navy
- Lopes Diogo
- Lordemann Anja Grosse
- Loschner Anthony L.
- Loubet Paul
- Loufti Bouchra
- Louis Guillame
- Lourenco Silvia
- Lovelace-Macon Lara
- Lowik Marije
- Lucet Jean Christophe
- Luna Carlos M.
- Luong Liem
- Luque Nestor
- Luton Dominique
- Lwin Nilar
- Lyons Ruth
- l’Her Erwan
- Maasikas Olavi
- Mabiala Oryane
- Machado Moïse
- Machado Sara
- Macheda Gabriel
- Madiha Hashmi
- Mahieu Rafael
- Mahy Sophie
- Maia Ana Raquel
- Maier Lars S.
- Maillet Mylène
- Maitre Thomas
- Malaque Ana
- Malfertheiner Maximilian
- Malik Nadia
- Mallon Paddy
- Maltez Fernando
- Malvy Denis
- Manda Victoria
- Mandelbrot Laurent
- Mankikian Julie
- Manning Edmund
- Manuel Aldric
- Marino Daniel
- Marino Flávio
- Markowicz Samuel
- Marques Ana
- Marquis Catherine
- Marsh Brian
- Marsh Laura
- Marshal Megan
- Marshall John C.
- Martelli Celina Turchi
- Martin Emily
- Martin-Blondel Guillaume
- Martin-Loeches Ignacio
- Martinot Martin
- Martins Ana
- Martins João
- Martins Nuno
- Martucci Gennaro
- Martynenko Olga
- Marwali Eva Miranda
- Maslove David
- Mason Sabina
- Masood Sobia
- Matan Moshe
- Mathew Meghena
- Mathieu Daniel
- Mattei Mathieu
- Matulevics Romans
- Maulin Laurence
- Maxwell Michael
- Maynar Javier
- Mazzoni Thierry
- Mc Evoy Natalie
- Mc Sweeney Lisa
- McArthur Colin
- McArthur Colin
- McCarthy Aine
- McCarthy Anne
- McCloskey Colin
- McConnochie Rachael
- McDermott Sherry
- McDonald Sarah E.
- McElroy Aine
- McElwee Samuel
- McEneany Victoria
- McGeer Allison
- McKay Chris
- McKeown Johnny
- McLean Kenneth A.
- McNally Paul
- McNicholas Bairbre
- McPartlan Elaine
- Meaney Edel
- Mear-Passard C. cile
- Mechlin Maggie
- Meher Maqsood
- Mele Ferruccio
- Melo Luis
- Memon Kashif
- Mendes Joao Joao
- Menkiti Ogechukwu
- Menon Kusum
- Mentré France
- Mentzer Alexander J.
- Mercier Emmanuelle
- Mercier Noémie
- Merckx Antoine
- Mergeay-Fabre Mayka
- Mergler Blake
- Merson Laura
- Mesquita António
- Metwally Osama
- Meybeck Agnès
- Meyer Dan
- Meynert Alison M.
- Meysonnier Vanina
- Meziane Amina
- Mezidi Mehdi
- Michelanglei C. line
- Michelet Isabelle
- Mihnovit Vladislav
- Mohammed Nassima Si
- Mohd-Hanafiah Farah Nadia
- Moin Asma
- Molina David
- Molinos Elena
- Molloy Brenda
- Mone Mary
- Monteiro Agostinho
- Monteiro Filipa Brás
- Montes Claudia
- Montrucchio Giorgia
- Moore Sarah
- Moore Shona C.
- Morlaes Louis Gerbaud
- Moro Lucia
- Motherway Catherine
- Motos Ana
- Mouquet Hugo
- Moyet Julien
- Mufti Aisha Kalsoom
- Mullaert Jimmy
- Munblit Daniel
- Muneeb Syed
- Munir Nadeem
- Murphy Aisling
- Murphy Aisling
- Murphy Lorna
- Murris Marlène
- Murthy Srinivas
- Musaab Himed
- Muvindi Himasha
- Myrodia Dimitra Melia
- Müller Fredrik
- Müller Karl Erik
- Nagpal Dave
- Nagrebetsky Alex
- Narayanan Nageswaran
- Nazerali-Maitland Alasdair
- Neant Nadège
- Nekliudov Nikita
- Neto Ary Serpa
- Neto Raul
- Neumann Emily
- Ng Pauline Yeung
- Nghi Anthony
- Nguyen Duc
- Nichol Alistair
- Nitayavardhana Prompak
- Nonas Stephanie
- Nor Basri Mat
- Nor Basri Mat
- Noret Marion
- Norman Lisa
- Notari Alessandra
- Noursadeghi Mahdad
- Nowinski Adam
- Nseir Saad
- Nunez Jose I.
- Nurnaningsih Nurnaningsih
- Nyamankolly Elsa
- Occhipinti Giovanna
- OConnor Derbrenn
- Ogston Tawnya
- Ogura Takayuki
- Oliveira João
- Oliveira Larissa
- Olliaro Piero L.
- Ong David S. Y.
- Oosthuyzen Wilna
- Opavsky Anne
- Openshaw Peter
- Orakzai Saijad
- Orozco-Chamorro Claudia Milena
- Ortoleva Jamel
- Osatnik Javier
- Ouamara Nadia
- Ouissa Rachida
- Oziol Eric
- O’Callaghan Annmarie
- O’Donnell Max
- O’Halloran Sophie
- O’Hearn Katie
- O’Shea Linda
- O’Sullivan Miriam
- Pagadoy Maïder
- Pages Justine
- Palacios Amanda
- Palacios Mario
- Palmarini Massimo
- Panarello Giovanna
- Panda Prasan Kumar
- Paneru Hem
- Panigada Mauro
- Pansu Nathalie
- Papadopoulos Aurélie
- Parke Rachael
- Parker Melissa
- Parra Briseida
- Pasha Taha
- Pasquier J. rémie
- Pastene Bruno
- Patauner Fabian
- Patricio Patricia
- Patrier Juliette
- Patrão Luís
- Patterson Lisa
- Pattnaik Rajyabardhan
- Paul Christelle
- Paul Mical
- Paulos Jorge
- Paxton William A.
- Payen Jean-François
- Peelman Florent
- Peiffer-Smadja Nathan
- Peigne Vincent
- Pejkovska Mare
- Pelosi Paolo
- Peltan Ithan D.
- Pereira Rui
- Perez Daniel
- Periel Luis
- Perpoint Thomas
- Perrot Clara Mouton
- Pesenti Antonio
- Pestre Vincent
- Petrou Lenka
- Petrov-Sanchez Ventzislava
- Petrovic Michele
- Pettersen Frank Olav
- Peytavin Gilles
- Pharand Scott
- Picard Walter
- Picone Olivier
- Pierobon Carola
- Piersma Djura
- Pimentel Carlos
- Pinto Raquel
- Pires Catarina
- Pironneau Isabelle
- Piroth Lionel
- Pius Riinu
- Plantier Laurent
- Poissy Julien
- Pokeerbux Ryadh
- Poli Sergio
- Pollakis Georgios
- Ponscarme Diane
- Post Andra-Maris
- Postma Douwe F.
- Povoa Pedro
- Powis Jeff
- Prapa Sofia
- Preau S. bastien
- Prebensen Christian
- Preiser Jean-Charles
- Prinssen Anton
- Pritchard Mark G.
- Priyadarshani Gamage Dona Dilanthi
- Proença Lucia
- Pudota Sravya
- Pulicken Mathew
- Purcell Gregory
- Puéchal Oriane
- Póvoas Diana
- Quesada Luisa
- Quinones-Cardona Vilmaris
- Quist-Paulsen Else
- Quraishi Mohammed
- Rabaud Christian
- Rabindrarajan Ebenezer
- Rafael Aldo
- Rafiq Marie
- Rahutullah Arsalan
- Rainieri Fernando
- Ramachandran Pratheema
- Ramakrishnan Nagarajan
- Ramalho José
- Rammaert Blandine
- Ramos Grazielle Viana
- Rana Asim
- Rangappa Rajavardhan
- Ranjan Ritika
- Rapp Christophe
- Rashan Aasiyah
- Rashan Thalha
- Rasheed Ghulam
- Rasmin Menaldi
- Rau Cornelius
- Raza Ali
- Real Andre
- Rebaudet Stanislas
- Redl Sarah
- Reeve Brenda
- Rego Caroline Martins
- Rehman Attaur
- Reid Liadain
- Reid Liadain
- Reikvam Dag Henrik
- Reis Renato
- Rello Jordi
- Remppis Jonathan
- Remy Martine
- Ren Hongru
- Renk Hanna
- Resseguier Anne-Sophie
- Revest Matthieu
- Rewa Oleksa
- Reyes Luis Felipe
- Reyes Tiago
- Ribeiro Ana Freitas
- Ribeiro Maria Ines
- Richardson David
- Richardson Denise
- Richier Laurent
- Riera Jordi
- Rincon Diego Fernando Bautista
- Rios Ana L.
- Rishu Asgar
- Rispal Patrick
- Risso Karine
- Rizer Nicholas
- Robba Chiara
- Roberto André
- Roberts Stephanie
- Robertson David L.
- Robineau Olivier
- Roche-Campo Ferran
- Rodari Paola
- Rodeia Simão
- Roessler Bernhard
- Roger Pierre-Marie
- Rojek Amanda
- Rojo Jaime Cruz
- Romaru Juliette
- Roncon-Albuquerque Roberto
- Roriz M. lanie
- Rosa-Calatrava Manuel
- Rose Michael
- Rosenberger Dorothea
- Rossanese Andrea
- Rossetti Matteo
- Rossignol B. nédicte
- Rossignol Patrick
- Rousset Stella
- Roy Carine
- Roze Benoît
- Rusmawatiningtyas Desy
- Russell Clark D.
- Ryan Maeve
- Ryan Maria
- Ryckaert Steffi
- Rätsep Indrek
- Saba Isabela
- Sadaf Sairah
- Sadat Musharaf
- Sahraei Valla
- Saidani Nadia
- Saint-Gilles Maximilien
- Sakiyalak Pranya
- Salahuddin Nawal
- Salazar Leonardo
- Saleem Jodat
- Sales Gabriele
- Sallaberry Stéphane
- Salvator H. lène
- Sanchez Olivier
- Sanchez-Miralles Angel
- Sancho-Shimizu Vanessa
- Sandhu Gyan
- Sandhu Zulfiqar
- Sandrine Pierre-François
- Sandulescu Oana
- Sanharawi Mohammed El
- Sant Ceila Maria
- Santo Catarina Espírito
- Santos Marlene
- Santos Marta Leal
- Sarfo-Mensah Shirley
- Sarton Benjamine
- Satyapriya Sree
- Satyawati Rumaisah
- Saviciute Egle
- Schaffer Justin
- Schermer Tjard
- Scherpereel Arnaud
- Schneider Marion
- Schroll Stephan
- Schwameis Michael
- Scott Janet T.
- Scott-Brown James
- Sedillot Nicholas
- Seitz Tamara
- Selvanayagam Jaganathan
- Semaille Caroline
- Semedi Bambang Pujo
- Semple Malcolm G.
- Senneville Eric
- Sequeira Filipa
- Sequeira T. nia
- Shadowitz Ellen
- Shah Naseem Ali
- Shamsah Mohammad
- Sharjeel Shaikh
- Sharma Pratima
- Shaw Catherine A.
- Shaw Victoria
- Sheharyar Ashraf
- Shetty Rajesh Mohan
- Shi Haixia
- Shiekh Mohiuddin
- Shimizu Keiki
- Shrapnel Sally
- Shrestha Pramesh Sundar
- Shrestha Shubha Kalyan
- Shukeri Wan Fadzlina Wan Muhd
- Shum Hoi Ping
- Sibiude Jeanne
- Siddiqui Atif
- Sigfrid Louise
- Sikander Rana Imran
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- Silva Maria Joao
- Silva Rogério
- Sin Wai Ching
- Singh Budha Charan
- Singh Moirangthem Bikram
- Singh Punam
- Sitompul Pompini Agustina
- Skeie Linda Gail
- Skogen Vegard
- Smith Sue
- Smood Benjamin
- Smyth Coilin
- Smyth Michelle
- Smyth Michelle
- Snacken Morgane
- So Dominic
- Sobrino José Luis Bernal
- Solomon Joshua
- Solomon Tom
- Somers Emily
- Sommet Agnès
- Song Myung Jin
- Song Rima
- Song Tae
- Sotto Albert
- Soum Edouard
- Sousa Ana Chora
- Sousa Marta
- Sperry Alexandra
- Spinuzza Elisabetta
- Sriskandan Shiranee
- Stabler Sarah
- Staudinger Thomas
- Stecher Stephanie-Susanne
- Stienstra Ymkje
- Stiksrud Birgitte
- Stolz Eva
- Stone Amy
- Streinu-Cercel Adrian
- Streinu-Cercel Anca
- Stuart Ami
- Stuart David
- Suen Gabriel
- Suen Jacky Y.
- Sultana Asfia
- Summers Charlotte
- Supic Dubravka
- Surovcová Magdalena
- Svistunov Andrey
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Taccone Fabio S.
- Tagherset Lysa
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tampubolon Maria Lawrensia
- Tanaka Hiroyuki
- Taqdees Huda
- Taqi Arshad
- Tardivon Coralie
- Tattevin Pierre
- Taufik M. Azhari
- Tawfik Hassan
- Tedder Richard S.
- Teixeira João
- Tejada Sofia
- Tellier Marie-Capucine
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
- Tessier-Grenier Hubert
- Tey Adrian
- Thakur Anand
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tissot Noémie
- Toki Maria
- Tonby Kristian
- Torre Marta
- Torres Antoni
- Torres Margarida
- Torres-Zevallos Hernando
- Towers Michael
- Trapani Tony
- Treoux Théo
- Tromeur C. cile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turmel Jean-Marie
- Turtle Lance C. W.
- Twardowski Pawel
- Téoulé François
- Uchiyama Makoto
- Udayanga P. G. Ishara
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
- van der Vekens Nicky
- van der Voort Peter
- van der Werf Sylvie
- van Gulik Laura
- van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Vasconcelos Malte Kohns
- Vauchy Charline
- Vecham Pavan Kumar
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vickers James
- Vidal José Ernesto
- Vieira C. sar
- Vijayan Deepak
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Vijayaraghavan Bharath Kumar Tirupakuzhi
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wesselius Sanne
- West T. Eoin
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Suzette
- Williams Virginie
- Wils Evert-Jan
- Wong Calvin
- Xynogalas Ioannis
- Yamazaki Masaki
- Yazdanpanah Yazdan
- Yelnik C. cile
- Yerkovich Stephanie
- Yiu Ng Wing
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Yuliarto Saptadi
- Zaaqoq Akram
- Zabbe Marion
- Zahran Maram
- Zambon Maria
- Zanella Alberto
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2022
- Field of study
Background: Up to 30% of hospitalised patients with COVID-19 require advanced respiratory support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation (NIV), or invasive mechanical ventilation (IMV). We aimed to describe the clinical characteristics, outcomes and risk factors for failing non-invasive respiratory support in patients treated with severe COVID-19 during the first two years of the pandemic in high-income countries (HICs) and low middle-income countries (LMICs). Methods: This is a multinational, multicentre, prospective cohort study embedded in the ISARIC-WHO COVID-19 Clinical Characterisation Protocol. Patients with laboratory-confirmed SARS-CoV-2 infection who required hospital admission were recruited prospectively. Patients treated with HFNC, NIV, or IMV within the first 24 h of hospital admission were included in this study. Descriptive statistics, random forest, and logistic regression analyses were used to describe clinical characteristics and compare clinical outcomes among patients treated with the different types of advanced respiratory support. Results: A total of 66,565 patients were included in this study. Overall, 82.6% of patients were treated in HIC, and 40.6% were admitted to the hospital during the first pandemic wave. During the first 24 h after hospital admission, patients in HICs were more frequently treated with HFNC (48.0%), followed by NIV (38.6%) and IMV (13.4%). In contrast, patients admitted in lower- and middle-income countries (LMICs) were less frequently treated with HFNC (16.1%) and the majority received IMV (59.1%). The failure rate of non-invasive respiratory support (i.e. HFNC or NIV) was 15.5%, of which 71.2% were from HIC and 28.8% from LMIC. The variables most strongly associated with non-invasive ventilation failure, defined as progression to IMV, were high leukocyte counts at hospital admission (OR [95%CI]; 5.86 [4.83–7.10]), treatment in an LMIC (OR [95%CI]; 2.04 [1.97–2.11]), and tachypnoea at hospital admission (OR [95%CI]; 1.16 [1.14–1.18]). Patients who failed HFNC/NIV had a higher 28-day fatality ratio (OR [95%CI]; 1.27 [1.25–1.30]). Conclusions: In the present international cohort, the most frequently used advanced respiratory support was the HFNC. However, IMV was used more often in LMIC. Higher leucocyte count, tachypnoea, and treatment in LMIC were risk factors for HFNC/NIV failure. HFNC/NIV failure was related to worse clinical outcomes, such as 28-day mortality. Trial registration This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable
Paediatric COVID-19 mortality: a database analysis of the impact of health resource disparity
- Author
- Aasiyah Rashan
- Abid Khatak
- Abigail Beane
- Adrian Streinu-Cercel
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
- Agnes Meybeck
- Agnes Sommet
- Agnieszka Oldakowska
- Agostinho Monteiro
- Ahmad Afiq Ramli
- Ahmad Kashfi Rahman
- Ahmed Farooq
- Aidan Burrell
- Albert Groenendijk
- Albert Sotto
- Albertus Beishuizen
- Aldric Manuel
- Alexa Debard
- Alexander Daniel Cornet
- Alexander J Mentzer
- Alexandra Bedossa
- Alexandra Coelho
- Alexandre Ducancelle
- Alexandre Gaymard
- Alexandre Hoctin
- Ali Hachemi
- Alif Adlan Thabit
- Alison M. Meynert
- Alistair Nichol
- Alpha Diallo
- Alphonsine Diouf
- AM Udara Attanyake
- Amanda Corley
- Amanda Rojek
- Amandine Gagneux-Brunon
- Amina Meziane
- Amirul Asyraf
- Amna Faheem
- Amélie Valran
- Ana Freitas Ribeiro
- Ana L Rios
- Ana Martins
- Ana Silva Filipe
- Anant Kataria
- Anca Streinu-Cercel
- Andrea Angheben
- Andrea Rossanese
- Andrew Dagens
- Andrew Udy
- Andrey Svistunov
- André Cabié
- André Dias
- Andy Law
- Anika Atique
- Anilawati Mat Jelani
- Anissa Chair
- Anja Grosse Lordemann
- Anjellica Chen
- Anna Beltrame
- Anne Conrad
- Anne Guillaumot
- Anne McCarthy
- Anne-Hélène Boivin
- Anne-Marie Guerguerian
- Anne-Sophie Boureau
- Anne-Sophie Resseguier
- Annelies Verbon
- Annemarie B. Docherty
- Annmarie O'Callaghan
- Ansley Hamer
- Anthony L. Loschner
- Anthony Lemeur
- Anthony Nghi
- Antoine Cheret
- Antoine Khalil
- Antoine Kimmoun
- Antoine Merckx
- Antonia Ho
- Antonio Lalueza
- António Mesquita
- Arabella Fahy
- Ardiyan Apriyana
- Arfan Ikram
- Aria Kekalih
- Arianne Joy Corpuz
- Arjen M Dondorp
- Arnaud Scherpereel
- Arsene Kpangon
- Ary Serpa Neto
- Asgar Rishu
- Ashraf Sheharyar
- Asma Moin
- Astarini Hidayah
- Attaur Rehman
- Audrey Barrelet
- Aurore Bousquet
- Aurélie Papadopoulos
- Aurélie Veislinger
- Aurélie Wiedemann
- Axelle Braconnier
- Azlan Mat Soom
- B. P Edouard Soum
- Barbara Wanjiru Citarella
- Basri Mat Nor
- Beatrice Alex
- Benedict Sim Heng
- Benjamin Bach
- Benjamin Lefèvre
- Benjamine Sarton
- Benoit Thill
- Benoit Visseaux
- Benoît Roze
- Bernard Cholley
- Bernardo Ferreira
- Bertrand Dussol
- Bharath Kumar Vijayaraghavan
- Bianca Boxma
- Biing Horng Lee
- Blandine Rammaert
- Bouchra Loufti
- Brenda Reeve
- Brigitte Elharrar
- Bronner P Gonçalves
- Bronner P. Gonçalves
- Bruno Levy
- Bruno Lina
- Bruno Pastene
- Bénédicte Lefebvre
- Bénédicte Rossignol
- Calum Semple
- Calvin Wong
- Cameron J. Fairfield
- Camile Bouisse
- Camille Couffignal
- Carine Roy
- Carlo Giaquinto
- Carlos Alexandre Brito
- Carlos Lumbreras Bermejo
- Carlos Pimentel
- Carola Pierobon
- Carolien van Netten
- Caroline Martins Rego
- Caroline Mudara
- Caroline Semaille
- Carolline Araujo
- Carrol Gamble
- Catarina Espírito Santo
- Catarina Pires
- Catherine A. Shaw
- Catherine Chakveatze
- Catherine Chirouze
- Catherine L. Hough
- Cecile Azoulay
- Cecile Yelnik
- Cedric Laouenan
- Ceila Sant'Ana Malaque
- Celina Turchi Martelli
- Chamira Kodippily
- Chan Chee Eng
- Charlene Da Silveira
- Charline Vauchy
- Charlotte Salmon Gandonniere
- Charlotte Summers
- Chian Hui Yeoh
- Chiara Simona Cardellino
- Chloe Donohue
- Christel Arnold-Day
- Christelle Chantalat Auger
- Christelle Delmas
- Christelle Paul
- Christelle Tual
- Christian Rabaud
- Christiana Kartsonaki
- Christl A Donnelly
- Christophe Fraser
- Christophe Rapp
- Christopher A. Green
- Claire Andrejak
- Claire Lévy-Marchal
- Clara Flateau
- Clara Mouton Perrot
- Clare Jackson
- Clark D. Russell
- Claudia Figueiredo-Mello
- Claudia Milena Orozco-Chamorro
- Claudia Montes
- Claudina Cruz
- Claudine Badr
- Claudio Duarte Fonseca
- Clotilde Allavena
- Clément Le Bihan
- Colin McArthur
- Coline Jaud-Fischer
- Coralie Khan
- Coralie Tardivon
- Corine Delsing
- Corinne Daniel
- Cornelius Rau
- Courtney Greene
- Cynthia Braga
- Cyril Cadoz
- Cyril Le Bris
- Cécile Goujard
- Cécile Mear-Passard
- Cécile Tromeur
- Cédric Joseph
- Céline Dorival
- Céline Ficko
- Céline Michelanglei
- César Vieira
- Dafsah Juzar
- Damien Bouhour
- Daniel Glikman
- Daniel Haber
- Daniel Marino
- Daniel Mathieu
- Daniel Munblit
- Daniel Perez
- Daniela Guerreiro
- Danielle Jaafar
- David L. Robertson
- David Maslove
- David Richardson
- David S.Y. Ong
- David Stuart
- David Thomson
- David Zucman
- Debby Bogaert
- Deepashankari Suppiah
- Dehbia Benkerrou
- Delphine Bachelet
- Delphine Bergeaud
- Delphine Lariviere
- Demetrios Kutsogiannis
- Denis Butnaru
- Denis Garot
- Denis Malvy
- Denisa Khoo
- Desy Rusmawatiningtyas
- Detlef Kindgen-Milles
- Dewi Guellec
- Diana Adrião
- Diana Hernández
- Diana Póvoas
- Diane Descamps
- Diane Ponscarme
- Didier Laureillard
- Diego Fernando Rincon
- Diogo Borges
- Diogo Lopes
- Diptesh Aryal
- Djura Piersma
- Dominique Deplanque
- Dominique Luton
- Dounia Bouhmani
- Douwe F. Postma
- Duc Nguyen
- Dyah Kanya Wati
- Dzawani Muhamad
- Eder Caceres
- Edmund Manning
- Eglantine Ferrand Devouge
- Egle Saviciute
- Elias Iosifidis
- Elisa Demonchy
- Elisabeth Botelho-Nevers
- Elise Artaud-Macari
- Ellen Shadowitz
- Elodie Curlier
- Elsa Nyamankolly
- Ema Leal
- Eman Al Qasim
- Emma C. Thomson
- Emma Clarke
- Emma Costigan
- Emmanuel Roilides
- Emmanuelle A Dankwa
- Emmanuelle Denis
- Emmanuelle Mercier
- Eric D'ortenzio
- Eric Delaveuve
- Eric Oziol
- Eric Senneville
- Erlina Burhan
- Ernita Akmal
- Erwan Fourn
- Erwan L'her
- Esteban Garcia-Gallo
- Etienne De Montmollin
- Eva Geraud
- Eva Miranda Marwali
- Eve Defous
- Evert-Jan Wils
- Ewa Talarek
- Ewen M. Harrison
- Fabio S. Taccone
- Fabrice Laine
- Fakhir Haidri
- Fanny Vuotto
- Fara Diop
- Farah Nadiah Bidin
- Felwa Bin Humaid
- Fernando Augusto Bozza
- Fernando Maltez
- Filipa Cardoso
- Filipe Cardoso
- Fiona Griffiths
- Firouzé Bani-Sadr
- Florence Jego
- Florent Peelman
- Florentia Kaguelidou
- France Mentré
- François Angoulvant
- François Bissuel
- François Bompart
- François Dubos
- François Goehringer
- François Lellouche
- François Martin Carrier
- François Téoulé
- François-Xavier Catherine
- François-Xavier Ferrand
- François-Xavier Lescure
- Félix Djossou
- Gabriel Macheda
- Gail Carson
- Gamage Dona Priyadarshani
- Gan Ee Xian
- Ganesh Kumar
- Gary Leeming
- Geoffrey Liegeon
- Georges Le Falher
- Georgios Pollakis
- Geraldine Goco
- Gianluigi Li Bassi
- Gilles Peytavin
- Giri Shan Rajahram
- Giulia Bertoli
- Graham S. Cooke
- Grazielle Viana Ramos
- Gry Kloumann Bekken
- Grégory Corvaisier
- Gugapriyaa Muyandy
- Guillame Louis
- Guillaume Lingas
- Guillaume Martin-Blondel
- Guillermo Giordano
- Guillermo Maestro de la Calle
- Guylaine Castor-Alexandre
- Gwenaël Le Moal
- Gwenhaël Colin
- Ha Sha Lene
- Hajnal-Gabriela Illes
- Hanan Fateena
- Hanna Renk
- Hannah Habraken
- Hans Martin Bosse
- Harald Vonkeman
- Hashmi Madiha
- Hayley Hardwick
- Heidi Dalton
- Heidi Gruner
- Heidi Jean Dalton
- Heng Gee Lee
- Hervé Le Nagard
- Hiba Zayyad
- Hikombo Hitoto
- Himasha Muvindi
- Himed Musaab
- Hiu Jian Chua
- Hodane Yonis
- Hon Shen Png
- Hongru Ren
- Hubert Tessier-Grenier
- Huda Alfoudri
- Hugo Inácio
- Hugo Mouquet Ben Morton
- Hugues Aumaître
- Hugues Cordel
- Husna Begum
- Hwa Jin Cho
- Hélène Espérou
- Hélène Salvator
- Ikram Houas
- Ilka Engelmann
- Ilonka van Veen
- Ingrid G Bustos
- Irfan Khan
- Isabela Bolaños
- Isabelle Delacroix
- Isabelle Enderle
- Isabelle Fabre
- Isabelle Gorenne
- Isabelle Hoffmann
- Isabelle Michelet
- Isabelle Pironneau
- Ithan D. Peltan
- Ivy Cerelia Valerie
- J. Kenneth Baillie
- Jacky Y. Suen
- Jade Ghosn
- Jaganathan Selvanayagam
- Jaime Cruz Rojo
- Jake Dunning
- James Joshua Douglas
- James Lee
- James Scott-Brown
- James Vickers
- Jananee Thirumanickam
- Janet Harrison
- Janet T. Scott
- Jaques Sztajnbok
- Jarne Van Hattem
- Jason Bouziotis
- Jean Baptiste Assie
- Jean Christophe Lucet
- Jean-Benoît Arlet
- Jean-Charles Gagnard
- Jean-Charles Preiser
- Jean-Christophe Goffard
- Jean-Daniel Lelievre
- Jean-François Payen
- Jean-François Timsit
- Jean-Luc Diehl
- Jean-Marc Chapplain
- Jean-Marie Turmel
- Jean-Sébastien Hulot
- Jeanne Sibiude
- Jeanne Truong
- Jee Yan Ong
- Jennifer Lee
- Jenny Lennon
- Jeremie Guedj
- Jess Gibson
- Jia Shyi Loy
- Jia Wei
- Jillian Deacon
- Jimmy Ming-Yang Hsu
- Jimmy Mullaert
- Jin Yi Goh
- Jo Dalton
- Joana Alves Cabrita
- Joana Ferrão
- Joaquín Baruch
- Job van der Palen
- Johann Auchabie
- John F Fraser
- John Marshall
- Jolanta Popielska
- Jonathan Bitton
- Jonathan Chua
- Jonathan Remppis
- Jordan Zhien Toh
- Jorge Dantas
- Jorge Fernandes
- Jorge Paulos
- Jose Andres Calvache
- Jose M. Mandei
- Joshua Solomon
- José Casimiro
- José Ernesto Vidal
- José Luis Sobrino
- José Ramalho
- João Estevão
- João Teixeira
- Juan Luis Bermúdez
- Jules Bauer
- Julian Chica
- Juliana Damas
- Julie Chas
- Julie Mankikian
- Julien Jabot
- Julien Moyet
- Julien Poissy
- Juliette Patrier
- Juliette Romaru
- Justine Pages Maïder Pagadoy
- Jérémie Pasquier
- Jérôme Dimet
- Kah Chuan Lim
- Kalaiarasu Peariasamy
- Kalynn Kennon
- Karen Delavigne
- Karine Bezulier
- Karine Faure
- Karine Risso
- Karisha Sivam
- Karl Erik Müller
- Karolina Nowicka
- Katharina Weil
- Kathy Brickell
- Katie O'Hearn
- Kazali Enagnon Alidjnou
- Kenneth A McLean
- Ker Hong Bee
- Kevin Katz
- Khor How Kiat
- Kim Keat Tan
- Kok Wei Hao
- Kong Yeow Kang
- Konrad Zawadka
- Krishna Bhavsar
- Kuan Pei Xuan
- Kusum Menon
- Kévin Alexandre
- Kévin Bouiller
- Kévin Didier
- Laetitia Bodenes
- Lai Hui Pang
- Lance C.W. Turtle
- Lara Absil
- Lars Heggelund
- Laura Marsh
- Laura Merson
- Laure Goubert
- Lauren Deconninck
- Laurence Bouillet
- Laurence Maulin
- Laurent Abel
- Laurent Bitker
- Laurent Guilleminault
- Laurent Lefebvre
- Laurent Mandelbrot
- Laurent Plantier
- Laurent Richier
- Laurène Azemar
- Lee Lee Low
- Leong Chee Loon
- Leong Chin Tho
- Liem Luong
- Lila Bouadma
- Lim Lina
- Lim Saio Xian
- Lim Yuen Han
- Lina Morales Cely
- Linda O'Shea
- Lionel Eric Benjiman
- Lionel Piroth
- Lisa Norman
- Louis Gerbaud Morlaes
- Louise Sigfrid
- Lucia Moro
- Lucie Le Fevre
- Lucille Blumberg
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- Luís Val-Flores
- Lysa Tagherset
- M Azhari Taufik
- Mageswari Selvarajoo
- Mahdad Noursadeghi
- Maire-Laure Casanova
- Malcolm G. Semple
- Malte Kohns Vasconcelos
- Malte Kohns Vasconcelos
- Manuel Etienne
- Manuel Rosa-Calatrava
- Maram Zahran
- Marc Fabre
- Marc Lambert
- Marc Leone
- Marcel van den Berge
- Marcela Vieira Freire
- Margarida Torres
- Margaux Isnard
- Maria Amaral
- Maria Donnelly
- Maria Pokorska-Spiewak
- Maria Zambon
- Mariana Cascão
- Marie Bartoli
- Marie Connor
- Marie Gominet
- Marie Lachatre
- Marie Lacoste
- Marie Lagrange
- Marie Langelot-Richard
- Marie Rafiq
- Marie-Capucine Tellier
- Marie-Charlotte Chopin
- Marie-Christine Carret
- Marie-Pierre Debray
- Marieke Haalboom
- Marielle Boyer-Besseyre
- Marielle Buisson
- Marije Lowik
- Marina Esposito-Farèse
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- Petr Glybochko
- PG Ishara Udayanga
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- Phoebe Ampaw
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- Sophie Mahy
- Srinivas Murthy
- Stanislas Rebaudet
- Stella Rousset
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- Stephanie Yerkovich
- Stephen R Knight
- Steve Webb
- Stéphane Jaureguiberry
- Stéphane Lasry
- Stéphane Sallaberry
- Stéphanie Cousse
- Stéphanie Fry
- Subhash Acharya
- Sue Smith
- Suhaila Abdul Wahab
- Surain Raaj Thurai
- Suresh Kumar Chidambaram
- Sushil Khanal
- Suvintheran Thangavelu
- Swosti Joshi
- Syamin Asyraf Shahidan
- Sybille Bevilcaqua
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- Sylvie Behilill
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- Sylvie Van Der Werf
- Sze Kye Teoh
- Séverine Ansart
- Tae Song
- Tahira Jamal Mohamed
- Tala Al-Dabbous
- Tan Pei Wen
- Tatiana Fonseca
- Teck Fung Wong
- Teresa Lawrence
- Thalha Rashan
- Tharmini Ravi
- Thavamany Kaleesvran
- Thibault Chiarabini
- Thierry Carmoi
- Thierry Mazzoni
- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thushan de Silva
- Théo Treoux
- Tiago Isidoro
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M. Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Todd C Lee
- Todd Karsies
- Tom Drake
- Tom Fletcher
- Tom Solomon
- Tony Trapani
- Tristan Gigante
- Tze Vee Soh
- Tze Yuan Tee
- Tânia Sequeira
- Valentine Campana
- Valeria Balan
- Valla Sahraei
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Vanessa Sancho-Shimizu
- Vanina Meysonnier
- Ventzislava Petrov-Sanchez
- Victor Fomin
- Victoria Manda
- Victoria Shaw
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubée
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinod Kumar
- Vinothini Krishnan
- Véronique Lemee
- Víctor Quirós González
- Waasila Jassat
- Walter Picard
- Wei Han Hoh
- Wei Shen Lim
- Wendy S. Barclay
- William A. Paxton
- William Dechert
- William Greenhalf
- Wilna Oosthuyzen
- Wim Dieperink
- Xavier Duval
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yaseen Arabi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Ymkje Stienstra
- Yoan Lavie-Badie
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zhang Duan Tham
- Zul Amali Kamaruddin
- Zulfiqar Sandhu
- Publication venue
- 'BMJ'
- Publication date
- 01/10/2022
- Field of study
Background The impact of the COVID-19 pandemic on paediatric populations varied between high-income countries (HICs) versus low-income to middle-income countries (LMICs). We sought to investigate differences in paediatric clinical outcomes and identify factors contributing to disparity between countries.Methods The International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) COVID-19 database was queried to include children under 19 years of age admitted to hospital from January 2020 to April 2021 with suspected or confirmed COVID-19 diagnosis. Univariate and multivariable analysis of contributing factors for mortality were assessed by country group (HICs vs LMICs) as defined by the World Bank criteria.Results A total of 12 860 children (3819 from 21 HICs and 9041 from 15 LMICs) participated in this study. Of these, 8961 were laboratory-confirmed and 3899 suspected COVID-19 cases. About 52% of LMICs children were black, and more than 40% were infants and adolescent. Overall in-hospital mortality rate (95% CI) was 3.3% [=(3.0% to 3.6%), higher in LMICs than HICs (4.0% (3.6% to 4.4%) and 1.7% (1.3% to 2.1%), respectively). There were significant differences between country income groups in intervention profile, with higher use of antibiotics, antivirals, corticosteroids, prone positioning, high flow nasal cannula, non-invasive and invasive mechanical ventilation in HICs. Out of the 439 mechanically ventilated children, mortality occurred in 106 (24.1%) subjects, which was higher in LMICs than HICs (89 (43.6%) vs 17 (7.2%) respectively). Pre-existing infectious comorbidities (tuberculosis and HIV) and some complications (bacterial pneumonia, acute respiratory distress syndrome and myocarditis) were significantly higher in LMICs compared with HICs. On multivariable analysis, LMIC as country income group was associated with increased risk of mortality (adjusted HR 4.73 (3.16 to 7.10)).Conclusion Mortality and morbidities were higher in LMICs than HICs, and it may be attributable to differences in patient demographics, complications and access to supportive and treatment modalities
Thrombotic and hemorrhagic complications of COVID-19 in adults hospitalized in high-income countries compared with those in adults hospitalized in low- and middle-income countries in an international registry
- Author
- Abdukahil Sheryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adam Elisabeth
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexander Peta MA
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ampaw Phoebe
- Andini Roberto
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baig Nadia
- Baillie J Kenneth
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S
- Barnett Saef Umar
- Barnikel Michaela
- Barrasa Helena
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Basri Muhammad Fadhli Hassin
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Beane Abigail
- Bedossa Alexandra
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Benny Binny
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Bissuel François
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Bosse Hans Martin
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Bozza Patricia T
- Braconnier Axelle
- Braga Cynthia
- Brandenburger Timo
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O
- Browne Alex
- Browne Shaunagh
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- Bryda Petra
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- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
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- Calligy Kate
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- Campana Valentine
- Campbell Paul
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- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castañeda Silvia
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavayas Alexandros
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chantalat Auger Christelle
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Che Kamaruddin Zul Amali
- Chen Anjellica
- Chen Yih-Sharng
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chin Tho Leong
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chua Hiu Jian
- Chua Jonathan
- Chávez Iñiguez Jonathan Samuel
- Cidade Jose Pedro
- Cisneros Herreros José Miguel
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Emma
- Clarke Jennifer
- Claure-Del Granado Rolando
- Clohisey Sara
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Jennifer
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- Collins Michael
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- Combs Pamela
- Connolly Jennifer
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- Copland Mary
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- Cornet Alexander Daniel
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- Cortegiani Andrea
- Corvaisier Grégory
- Costigan Emma
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Cregan Rachel
- Cristella Cosimo
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Bermúdez Juan Luis
- Cruz Rojo Jaime
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Cummings Matthew
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- Cárcel Sheila
- D'Aragon Frédérick
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
- Dabaliz Al-Awwab
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- Dalton Heidi
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A
- Dantas Jorge
- de Brito Carlos Alexandre Antunes
- de Castro Maisa Guimarães
- de Jong Menno
- de la Calle Guillermo Maestro
- de Loughry Gillian
- De Montmollin Etienne
- de Oliveira França Rafael Freitas
- de Piero Maria
- de Pinho Oliveira Ana Isabel
- De Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Dean David
- Debard Alexa
- DeBenedictis Bianca
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Delfos Nathalie M
- Deligiannis Ionna
- Dell'Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Dias André
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- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou Félix
- Docherty Annemarie B
- Doherty Helen
- Donnelly Christl A
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
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- Dournon Nathalie
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- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dryden Murray
- Dubee Vincent
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- Ducancelle Alexandre
- Duculan Toni
- Dudman Susanne
- Duggal Abhijit
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Echeverria-Villalobos Marco
- Eddington Devin P
- Egan Siobhan
- Eira Carla
- Ekow Harrison Samuel Bernard
- El Sanharawi Mohammed
- Elapavaluru Subbarao
- Elharrar Brigitte
- Eliza Mohamed Nik Nur
- Ellerbroek Jacobien
- Eloy Philippine
- Elshazly Tarek
- Enderle Isabelle
- Endo Tomoyuki
- Eng Chan Chee
- Engelmann Ilka
- Enouf Vincent
- Epaulard Olivier
- Escher Martina
- Esperatti Mariano
- Esperou Hélène
- Esposito-Farese Marina
- Estevão João
- Etienne Manuel
- Ettalhaoui Nadia
- Everding Anna Greti
- Evers Mirjam
- Fabre Isabelle
- Fabre Marc
- Faheem Amna
- Fahy Arabella
- Fairfield Cameron J
- Fanning Jonathon P
- Faria Pedro
- Fateena Hanan
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- Favory Raphaël
- Fayed Mohamed
- Feely Niamh
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- Fernandes Jorge
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- Gorenne Isabelle
- Gormley Conor
- Goubert Laure
- Goujard Cécile
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- Grable Margarite
- Graf Jeronimo
- Grandin Edward Wilson
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- Proença Lucia
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- Purcell Gregory
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- Valran Amélie
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- van den Berge Marcel
- Van der Feltz Machteld
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Someren Gréve Frank
- van Veen Ilonka
- Van Willigen Hugo
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasconcelos Malte Kohns
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira César
- Villanueva Joy Ann
- Villar Judit
- Villeneuve Pierre-Marc
- Villoldo Andrea
- Visseaux Benoit
- Visser Hannah
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Weil Katharina
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zacharowski Kai
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 30/06/2023
- Field of study
Background: COVID-19 has been associated with a broad range of thromboembolic, ischemic, and hemorrhagic complications (coagulopathy complications). Most studies have focused on patients with severe disease from high-income countries (HICs). Objectives: The main aims were to compare the frequency of coagulopathy complications in developing countries (low- and middle-income countries [LMICs]) with those in HICs, delineate the frequency across a range of treatment levels, and determine associations with in-hospital mortality. Methods: Adult patients enrolled in an observational, multinational registry, the International Severe Acute Respiratory and Emerging Infections COVID-19 study, between January 1, 2020, and September 15, 2021, met inclusion criteria, including admission to a hospital for laboratory-confirmed, acute COVID-19 and data on complications and survival. The advanced-treatment cohort received care, such as admission to the intensive care unit, mechanical ventilation, or inotropes or vasopressors; the basic-treatment cohort did not receive any of these interventions. Results: The study population included 495,682 patients from 52 countries, with 63% from LMICs and 85% in the basic treatment cohort. The frequency of coagulopathy complications was higher in HICs (0.76%-3.4%) than in LMICs (0.09%-1.22%). Complications were more frequent in the advanced-treatment cohort than in the basic-treatment cohort. Coagulopathy complications were associated with increased in-hospital mortality (odds ratio, 1.58; 95% CI, 1.52-1.64). The increased mortality associated with these complications was higher in LMICs (58.5%) than in HICs (35.4%). After controlling for coagulopathy complications, treatment intensity, and multiple other factors, the mortality was higher among patients in LMICs than among patients in HICs (odds ratio, 1.45; 95% CI, 1.39-1.51). Conclusion: In a large, international registry of patients hospitalized for COVID-19, coagulopathy complications were more frequent in HICs than in LMICs (developing countries). Increased mortality associated with coagulopathy complications was of a greater magnitude among patients in LMICs. Additional research is needed regarding timely diagnosis of and intervention for coagulation derangements associated with COVID-19, particularly for limited-resource settings
Implementation of Recommendations on the Use of Corticosteroids in Severe COVID-19
- Author
- Aasiyah Rashan
- Abby Hurd
- Abdou Gai
- Abdulrahman Al-Fares
- Abhijit Duggal
- Abigail Beane
- Abubacarr Jagne
- Adam Ali
- Adam Hall
- Adam Nowinski
- Adrian Ceccato
- Adrian Streinu-Cercel
- Adrian Tey
- Adrien Auvet
- Adrien Lemaignen
- Adrienne Chan
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- Thomas Flament
- Thomas Guimard
- Thomas Maitre
- Thomas Perpoint
- Thomas Staudinger
- Thushan de Silva
- Tiago Isidoro
- Tiffany Trouillon
- Timo Brandenburger
- Timothy M Uyeki
- Ting Soo Chow
- Tiphaine Goulenok
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tjard Schermer
- Todd C Lee
- Tom Fletcher
- Tom Solomon
- Tomoyuki Endo
- Toni Duculan
- Tony Trapani
- Toshiki Yokoyama
- Touxiong Yiaye
- Tristan Gigante
- Trude Steinsvik
- Tze Vee Soh
- Tze Yuan Tee
- Umberto D'Alessandro
- Usuf Effua
- Vadim Tieroshyn
- Valentine Campana
- Valérie Gaborieau
- Valérie Garrait
- Valérie Gissot
- Valla Sahraei
- Vanessa Sancho-Shimizu
- Vanessa Teotonio
- Vanina Meysonnier
- Vegard Skogen
- Ventzislava Petrov-Sanchez
- Véronique Lemee
- Vicente Souza-Dantas
- Victor Fomin
- Victoria Janes
- Victoria Manda
- Victoria Shaw
- Viladeth Praphasiri
- Vilmaris Quinones-Cardona
- Vincent Dinot
- Vincent Dubee
- Vincent Enouf
- Vincent Langlois
- Vincent Le Moing
- Vincent Peigne
- Vincent Pestre
- Vincent Thibault
- Vinothini Krishnan
- Virginie Williams
- Víctor Quirós González
- Vladislav Mihnovit
- Volkan Korten
- Wai Ching Sin
- Walter Picard
- Wei Han Hoh
- Wei Shen Lim
- Wendy S Barclay
- William A Paxton
- William Dechert
- William Finlayson
- William Greenhalf
- Wilna Oosthuyzen
- Wils Evert-Jan
- Wim Dieperink
- Wing Yiu Ng
- Xavier Duval
- Xin Ci Wong
- Yael Dishon
- Yan Chyi Tan
- Yanay Gorelik
- Yaseen Arabi
- Yash Doshi
- Yasmin Gani
- Yazdan Yazdanpanah
- Yen Tsen Saw
- Yew Sing Wong
- Yi Bin Ho
- Yi Lin Lee
- Yih-Sharng Chen
- Ymkje Stienstra
- Yoan Lavie-Badie
- Yoann Donohue
- Younes Ait Tamlihat
- Younes Kerroumi
- Yun Sii Ing
- Yuri Kida
- Yusing Gu
- Yvelynne Kelly
- Yves Levy
- Zeno Bisoffi
- Zhang Duan Tham
- Zul Amali Che Kamaruddin
- Zulfiqar Sandhu
- Publication venue
- Publication date
- 01/12/2023
- Field of study
Importance: Research diversity and representativeness are paramount in building trust, generating valid biomedical knowledge, and possibly in implementing clinical guidelines. Objectives: To compare variations over time and across World Health Organization (WHO) geographic regions of corticosteroid use for treatment of severe COVID-19; secondary objectives were to evaluate the association between the timing of publication of the RECOVERY (Randomised Evaluation of COVID-19 Therapy) trial (June 2020) and the WHO guidelines for corticosteroids (September 2020) and the temporal trends observed in corticosteroid use by region and to describe the geographic distribution of the recruitment in clinical trials that informed the WHO recommendation. Design, setting, and participants: This prospective cohort study of 434 851 patients was conducted between January 31, 2020, and September 2, 2022, in 63 countries worldwide. The data were collected under the auspices of the International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC)-WHO Clinical Characterisation Protocol for Severe Emerging Infections. Analyses were restricted to patients hospitalized for severe COVID-19 (a subset of the ISARIC data set). Exposure: Corticosteroid use as reported to the ISARIC-WHO Clinical Characterisation Protocol for Severe Emerging Infections. Main outcomes and measures: Number and percentage of patients hospitalized with severe COVID-19 who received corticosteroids by time period and by WHO geographic region. Results: Among 434 851 patients with confirmed severe or critical COVID-19 for whom receipt of corticosteroids could be ascertained (median [IQR] age, 61.0 [48.0-74.0] years; 53.0% male), 174 307 (40.1%) received corticosteroids during the study period. Of the participants in clinical trials that informed the guideline, 91.6% were recruited from the United Kingdom. In all regions, corticosteroid use for severe COVID-19 increased, but this increase corresponded to the timing of the RECOVERY trial (time-interruption coefficient 1.0 [95% CI, 0.9-1.2]) and WHO guideline (time-interruption coefficient 1.9 [95% CI, 1.7-2.0]) publications only in Europe. At the end of the study period, corticosteroid use for treatment of severe COVID-19 was highest in the Americas (5421 of 6095 [88.9%]; 95% CI, 87.7-90.2) and lowest in Africa (31 588 of 185 191 [17.1%]; 95% CI, 16.8-17.3). Conclusions and relevance: The results of this cohort study showed that implementation of the guidelines for use of corticosteroids in the treatment of severe COVID-19 varied geographically. Uptake of corticosteroid treatment was lower in regions with limited clinical trial involvement. Improving research diversity and representativeness may facilitate timely knowledge uptake and guideline implementation
Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19
- Author
- Abdukahil heryl Ann
- Abdulkadir Nurul Najmee
- Abe Ryuzo
- Abel Laurent
- Abrous Amal
- Absil Lara
- Acker Andrew
- Adachi Shingo
- Adrião Diana
- Ahmed Shakeel
- Ainscough Kate
- Airlangga Eka
- Aisa Tharwat
- Akimoto Takako
- Akmal Ernita
- Akwani Chika
- Al Ageel Saleh
- Al Qasim Eman
- Al-dabbous Tala
- Al-Fares Abdulrahman
- Alalqam Razi
- Alberti Angela
- Alegesan Senthilkumar
- Alessi Marta
- Alex Beatrice
- Alexandre Kévin
- Alfoudri Huda
- Ali Imran
- Alidjnou Kazali Enagnon
- Aliudin Jeffrey
- Alkhafajee Qabas
- Allavena Clotilde
- Allou Nathalie
- Alves João
- Alves João Melo
- Alves Rita
- Amaral Maria
- Amira Nur
- Ampaw Phoebe
- Andini Roberto
- Andrey
- Andréjak Claire
- Angheben Andrea
- Angoulvant François
- Ansart Séverine
- Anthonidass Sivanesen
- Antonelli Massimo
- Antunes de Brito Carlos Alexandre
- Apriyana Ardiyan
- Arabi Yaseen
- Aragao Irene
- Arancibia Francisco
- Araujo Carolline
- Arcadipane Antonio
- Archambault Patrick
- Arenz Lukas
- Arlet Jean-Benoît
- Arnold-Day Christel
- Arora Lovkesh
- Arora Rakesh
- Artaud-Macari Elise
- Aryal Diptesh
- Asensio Angel
- Ashraf Muhammad
- Assie Jean Baptiste
- Asyraf Amirul
- Atif Minahel
- Atikah Ahmad Ridzuan Siti Nurul
- Atique Anika
- Auchabie Johann
- Aumaitre Hugues
- Auvet Adrien
- Ayadi Kamaluddin Muhammad Aisar
- Azemar Laurène
- Azoulay Cecile
- Bach Benjamin
- Bachelet Delphine
- Badr Claudine
- Baillie J. Kenneth
- Baird J Kevin
- Bak Erica
- Bakakos Agamemnon
- Bakar Nazreen Abu
- Bal Andriy
- Balakrishnan Mohanaprasanth
- Balan Valeria
- Balazote Pablo Serrano
- Bani-Sadr Firouzé
- Barbalho Renata
- Barbosa Nicholas Yuri
- Barclay Wendy S.
- Barnett Saef Umar
- Barnikel Michaela
- Barrelet Audrey
- Barrigoto Cleide
- Barrio Noelia García
- Bartoli Marie
- Baruch Joaquín
- Basmaci Romain
- Bassi Gianluigi Li
- Battaglini Denise
- Bauer Jules
- Bautista Rincon Diego Fernando
- Beane Abigail
- Bedossa Alexandra
- Bee Ker Hong
- Begum Husna
- Behilill Sylvie
- Beishuizen Albertus
- Bekken Gry Kloumann
- Beljantsev Aleksandr
- Bellemare David
- Beltrame Anna
- Beltrão Beatriz Amorim
- Beluze Marine
- Benech Nicolas
- Benjiman Lionel Eric
- Benkerrou Dehbia
- Bennett Suzanne
- Benny Binny
- Bento Luís
- Berdal Jan-Erik
- Bergeaud Delphine
- Bergin Hazel
- Bermejo Carlos Lumbreras
- Bernal Sobrino José Luis
- Bertoli Giulia
- Bertolino Lorenzo
- Bessis Simon
- Bevilcaqua Sybille
- Bezulier Karine
- Bhatt Amar
- Bhavsar Krishna
- Bianco Claudia
- Bidin Farah Nadiah
- Bin Kamarudin Mohd Nazlin
- Binti Mohd Yakop Siti Rohani
- Binti Zaidan Nor Zaila
- Bisoffi Zeno
- Bissuel François
- Biston Patrick
- Bitker Laurent
- Bitton Jonathan
- Blanco-Schweizer Pablo
- Blier Catherine
- Bloos Frank
- Blot Mathieu
- Blumberg Lucille
- Boccia Filomena
- Bodenes Laetitia
- Bogaert Debby
- Boivin Anne-Hélène
- Bolaños Isabela
- Bolze Pierre-Adrien
- Bompart François
- Borges Diogo
- Borie Raphaël
- Botelho-Nevers Elisabeth
- Bouadma Lila
- Bouchaud Olivier
- Bouchez Sabelline
- Bouhmani Dounia
- Bouhour Damien
- Bouiller Kévin
- Bouillet Laurence
- Bouisse Camile
- Boureau Anne-Sophie
- Bourke John
- Bouscambert Maude
- Bousquet Aurore
- Bouziotis Jason
- Boxma Bianca
- Boyer-Besseyre Marielle
- Boylan Maria
- Bozza Fernando Augusto
- Braconnier Axelle
- Braga Cynthia
- Brazzi Luca
- Breen Dorothy
- Breen Patrick
- Brewster David
- Brickell Kathy
- Brien Fionnuala O.
- Browne Shaunagh
- Brusse-Keizer Marjolein
- Bryda Petra
- Buchtele Nina
- Bugaeva Polina
- Buisson Marielle
- Burhan Erlina
- Burrell Aidan
- Bustos Ingrid G.
- Butnaru Denis
- Cabie André
- Cabral Susana
- Cabrita Joana Alves
- Caceres Eder
- Cadoz Cyril
- Callaghan Annmarie O.
- Calligy Kate
- Calvache Jose Andres
- Campana Valentine
- Campbell Paul
- Campisi Josie
- Camões João
- Cantero Mireia
- Caraux-Paz Pauline
- Cardellino Chiara Simona
- Cardoso Filipa
- Cardoso Filipe
- Cardoso Nelson
- Cardoso Sofia
- Carelli Simone
- Carlier Nicolas
- Carmoi Thierry
- Carney Gayle
- Carqueja Inês
- Carret Marie-Christine
- Carrier François Martin
- Carroll Ida
- Carson Gail
- Casanova Maire-Laure
- Cascão Mariana
- Casey Siobhan
- Casimiro José
- Cassandra Bailey
- Castanheira Nidyanara
- Castor-Alexandre Guylaine
- Castro Ivo
- Catarino Ana
- Catherine François-Xavier
- Cattaneo Paolo
- Cavalin Roberta
- Cavayas Alexandros
- Cely Lina Morales
- Cervantes-Gonzalez Minerva
- Chair Anissa
- Chakveatze Catherine
- Chan Adrienne
- Chand Meera
- Chantalat Auger Christelle
- Chapplain Jean-Marc
- Charpentier Charlotte
- Chas Julie
- Chavez-Iniquez Jonathan Samuel
- Che Kamaruddin Zul Amali
- Chen Anjellica
- Chen Yih-Sharng
- Chenard Léo
- Cheng Matthew Pellan
- Cheret Antoine
- Chia Jack Song
- Chiarabini Thibault
- Chica Julian
- Chidambaram Suresh Kumar
- Chirouze Catherine
- Chiumello Davide
- Cho Sung-Min
- Choileain Orna Ni
- Cholley Bernard
- Chopin Marie-Charlotte
- Chow Ting Soo
- Chow Yock Ping
- Chua Hiu Jian
- Chua Jonathan
- Chávez Iñiguez Jonathan Samuel
- Cidade Jose Pedro
- Citarella Barbara Wanjiru
- Citarella Barbara Wanjiru
- Ciullo Anna
- Clarke Jennifer
- Claure-Del Granado Rolando
- Claure-Del Granado Rolando
- Clohisey Sara
- Cobb Perren J.
- Codan Cassidy
- Cody Caitriona
- Coelho Alexandra
- Coles Jennifer
- Coles Megan
- Colin Gwenhaël
- Collins Michael
- Colombo Sebastiano Maria
- Combs Pamela
- Connolly Jennifer
- Connor Marie
- Conrad Anne
- Conway Elaine
- Cooke Graham S.
- Copland Mary
- Cordel Hugues
- Corley Amanda
- Cornelis Sabine
- Cornet Alexander Daniel
- Corpuz Arianne Joy
- Cortegiani Andrea
- Corvaisier Grégory
- Couffignal Camille
- Couffin-Cadiergues Sandrine
- Courtois Roxane
- Cousse Stéphanie
- Croonen Sabine
- Crowl Gloria
- Crump Jonathan
- Cruz Bermúdez Juan Luis
- Cruz Claudina
- Csete Marc
- Cullen Ailbhe
- Curley Gerard
- Curlier Elodie
- Curran Colleen
- Custodio Paula
- D'Ortenzio Eric
- da Silva Filipe Ana
- Da Silva Fernanda Dias
- Da Silveira Charlene
- Dabaliz Al-Awwab
- Dagens Andrew
- Dahly Darren
- Dai Danyang
- Dai Danyang
- Dalton Heidi
- Dalton Jo
- Daly Seamus
- Damas Juliana
- Daneman Nick
- Daniel Corinne
- Dankwa Emmanuelle A.
- Dantas Jorge
- de Loughry Gillian
- De Montmollin Etienne
- De Rosa Rosanna
- de Silva Thushan
- de Vries Peter
- Dean David
- Debard Alexa
- DeBenedictis Bianca
- Debray Marie-Pierre
- DeCastro Nathalie
- Dechert William
- Deconninck Lauren
- Decours Romain
- Defous Eve
- Delacroix Isabelle
- Delaveuve Eric
- Delavigne Karen
- Dell'Amore Andrea
- Delmas Christelle
- Delobel Pierre
- Delsing Corine
- Demonchy Elisa
- Denis Emmanuelle
- Deplanque Dominique
- Depuydt Pieter
- Desai Mehul
- Descamps Diane
- Desvallées Mathilde
- Devouge Eglantine Ferrand
- Dewayanti Santi
- Dhanger Pathik
- Diallo Alpha
- Diamantis Sylvain
- Diaz Juan Jose
- Diaz Rodrigo
- Didier Kévin
- Diehl Jean-Luc
- Dieperink Wim
- Dimet Jérôme
- Dinot Vincent
- Diop Fara
- Diouf Alphonsine
- Dishon Yael
- Djossou Félix
- Docherty Annemarie B.
- Doherty Helen
- Donnelly Christl A.
- Donnelly Maria
- Donohue Chloe
- Donohue Sean
- Donohue Yoann
- Doran Peter
- Dorival Céline
- Douglas James Joshua
- Dournon Nathalie
- Downer Triona
- Downey Joanne
- Downing Mark
- Drake Tom
- Driscoll Aoife
- Dryden Murray
- Dubee Vincent
- Dubos François
- Ducancelle Alexandre
- Duculan Toni
- Dudman Susanne
- Duggal Abhijit
- Dunand Paul
- Dunning Jake
- Duplaix Mathilde
- Durante-Mangoni Emanuele
- Durham Lucian
- Dussol Bertrand
- Duthoit Juliette
- Duval Xavier
- Dyrhol-Riise Anne Margarita
- Ean Sim Choon
- Echeverria-Villalobos Marco
- Edwards Eleanor
- Egan Siobhan
- El Sanharawi Mohammed
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- G Argin
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- Leeming Gary
- Lefebvre Bénédicte
- Lefebvre Laurent
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- Occhipinti Giovanna
- OConnor Derbrenn
- Ogura Takayuki
- Ohshimo Shinichiro
- Oliveira João
- Olliaro Piero L.
- Ong David S. Y.
- Ong Jee Yan
- Oosthuyzen Wilna
- Opavsky Anne
- Openshaw Peter
- Orozco-Chamorro Claudia Milena
- Ortoleva Jamel
- Osatnik Javier
- Othman Siti Zubaidah
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- Peariasamy Kalaiarasu
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- Peelman Florent
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- Postma Douwe F.
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- Preiser Jean-Charles
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- Purcell Gregory
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- Quesada Luisa
- Quist-Paulsen Else
- Quraishi Mohammed
- Qutishat Fadi
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- Rafael Aldo
- Rafiq Marie
- Rahardjani Mutia
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- Rajahram Giri Shan
- Ramakrishnan Nagarajan
- Ramalho José
- Ramli Ahmad Afiq
- Rammaert Blandine
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- Ranjan Ritika
- Rapp Christophe
- Rasmin Menaldi
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- Real Andre
- Rebaudet Stanislas
- Redl Sarah
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- Richardson David
- Richardson Denise
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- Roberto André
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- Rodari Paola
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- Rossignol Patrick
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- Sandhu Gyan
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- Sarfo-Mensah Shirley
- Sarmiento Iam Claire E.
- Sarton Benjamine
- Satyapriya Sree
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- Schwameis Michael
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- Scott-Brown James
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- Seitz Tamara
- Selvarajoo Mageswari
- Semaille Caroline
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- Semple Malcolm G.
- Senian Rasidah Bt
- Senneville Eric
- Sepulveda Claudia
- Sequeira Filipa
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- Shadowitz Ellen
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- Shaw Catherine A.
- Shaw Victoria
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- Streinu-Cercel Adrian
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- Stuart Ami
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- Su Richa
- Subekti Decy
- Suen Gabriel
- Suen Jacky Y.
- Sukumar Prasanth
- Sultana Asfia
- Summers Charlotte
- Supic Dubravka
- Suppiah Deepashankari
- Surovcová Magdalena
- Svistunov Suwarti
- Sweeney Lisa Mc
- Syahrin Sarah
- Syrigos Konstantinos
- Sztajnbok Jaques
- Szuldrzynski Konstanty
- Tabrizi Shirin
- Taccone Fabio S.
- Tagherset Lysa
- Taib Shahdattul Mawarni
- Taleb Sara
- Talsma Jelmer
- Tamlihat Younes Ait
- Tampubolon Maria Lawrensia
- Tan Kim Keat
- Tan Yan Chyi
- Tanaka Hiroyuki
- Tanaka Taku
- Taniguchi Hayato
- Tardivon Coralie
- Tattevin Pierre
- Taufik M Azhari
- Tawfik Hassan
- Tedder Richard S.
- Tee Tze Yuan
- Teixeira João
- Tellier Marie-Capucine
- Teoh Sze Kye
- Teotonio Vanessa
- Terpstra Pleun
- Terrier Olivier
- Terzi Nicolas
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- Tey Adrian
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- Thangavelu Suvintheran
- Theron Elmi
- Thibault Vincent
- Thiberville Simon-Djamel
- Thill Benoît
- Thirumanickam Jananee
- Tho Leong Chin
- Thompson Shaun
- Thomson David
- Thomson Emma C.
- Thorpe Mathew
- Thwaites Ryan S.
- Tierney Paul
- Tieroshyn Vadim
- Timashev Peter S.
- Timsit Jean-François
- Tirupakuzhi Vijayaraghavan Bharath Kumar
- Tissot Noémie
- Toal Fiona
- Toki Maria
- Tonby Kristian
- Tonnii Sia Loong
- Torre Marta
- Torres Antoni
- Torres-Zevallos Hernando
- Towers Michael
- Trapani Tony
- Tromeur Cécile
- Trontzas Ioannis
- Trouillon Tiffany
- Truong Jeanne
- Tual Christelle
- Tubiana Sarah
- Tuite Helen
- Turgeon Alexis F.
- Turmel Jean-Marie
- Turtle Lance C. W.
- Tveita Anders
- Twardowski Pawel
- Téoulé François
- Udy Andrew
- Ullrich Roman
- Uribe Alberto
- Usman Asad
- Uva Maria Sousa
- Uyeki Timothy M.
- Vajdovics Cristinava
- Val-Flores Luís
- Valran Amélie
- Van de Velde Stijn
- van den Berge Marcel
- van der Palen Job
- van der Valk Paul
- Van Der Vekens Nicky
- Van der Voort Peter
- Van Der Werf Sylvie
- van Gulik Laura
- Van Hattem Jarne
- van Netten Carolien
- van Veen Ilonka
- Vanel Noémie
- Vanoverschelde Henk
- Varghese Pooja
- Varrone Michael
- Vasudayan Shoban Raj
- Vauchy Charline
- Vecham Pavan Kumar
- Veeran Shaminee
- Veislinger Aurélie
- Vencken Sebastian
- Ventura Sara
- Verbon Annelies
- Vidal José Ernesto
- Vieira César
- Villanueva Joy Ann
- Villoldo Andrea
- Visseaux Benoit
- Vitiello Chiara
- Vonkeman Harald
- Vuotto Fanny
- Wahab Noor Hidayu
- Wahab Suhaila Abdul
- Wahid Nadirah Abdul
- Wainstein Marina
- Wainstein Marina
- Walsh Laura
- Wang Chih-Hsien
- Webb Steve
- Wei Jia
- Wen Tan Pei
- Wesselius Sanne
- Wham Murray
- Whelan Bryan
- White Nicole
- Wicky Paul Henri
- Wiedemann Aurélie
- Wijaya Surya Otto
- Wille Keith
- Willems Sue
- Williams Bailey
- Williams Patricia J.
- Williams Virginie
- Wils Evert-Jan
- Wittman Jessica
- Wong Calvin
- Wong Teck Fung
- Wong Xin Ci
- Wong Yew Sing
- Xian Gan Ee
- Xian Lim Saio
- Xynogalas Ioannis
- Yamazaki Masaki
- Yang Toh Jordan Zhien
- Yarad Elizabeth
- Yazdanpanah Yazdan
- Yelnik Cécile
- Yeoh Chian Hui
- Yerkovich Stephanie
- Yokoyama Toshiki
- Yonis Hodane
- Yousif Obada
- Zaaqoq Akram
- Zabbe Marion
- Zahid Masliza
- Zahran Maram
- Zambon Maria
- Zambrano Miguel
- Zanella Alberto
- Zaynah Nurul
- Zayyad Hiba
- Zoufaly Alexander
- Zucman David
- Publication venue
- Elsevier BV
- Publication date
- 26/05/2023
- Field of study
Introduction: Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods: This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results: Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. Conclusions: AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes