1,472 research outputs found
South-South knowledge intermediation: approaches to triangular cooperation in knowledge for development
This multi-disciplinary study explores a field of enquiry at the boundaries of information science and development studies. It is concerned with the facilitation of knowledge processes - processes of knowledge exchange and co-creation - in the international development sector. Additionally, this study considers the importance of human relationships and social networks (and power), and studies these in knowledge intermediation projects. The main gaps that are addressed regard the understanding of intermediating knowledge process concerned with learners situated (partly) across cultural, language, and political boundaries in developing countries. Such projects/programmes/approaches, coined South-South knowledge exchanges by the World Bank, have only seen very limited amount of research; the foci of this research are human relationships and initiation acts, which add further novelty. By mirroring ideas of triangular and South-South collaboration the thesis explores knowledge intermediation projects and three roles played by actors participating in such projects: the intermediary and facilitator of knowledge processes (usually backed by a funding body), someone sharing knowledge (knowledge holders), and someone learning from others (knowledge seeker). This study not only shows how these roles apply to knowledge intermediation projects but also addresses their influence on relational elements at the interpersonal level. Two case studies are used to show how knowledge intermediation projects in the international development sector are shaped by their approach (demand initiated, facilitator/funder initiated), especially in terms of the relationships they foster. The sociology of knowledge approach to discourse analysis (SKAD) is used in the study of the case studies, which is supplemented by social network analysis. After linking the discovered relationship patterns to the initiation acts in the respective case studies a picture emerges that offers two broad insights. Firstly, facilitator/funder initiation of South-South knowledge intermediation projects appears to lead to many potential relationships, most of them irrelevant to an individual and, therefore, unestablished. Secondly, demand initiation of South-South knowledge intermediation projects appears to lead to very few, yet highly relevant, relationships
Discursive structures in knowledge co-creation: analysing interactions with SKAD and Social Network Analysis
Wissen und Macht sind zentrale Konzepte in der internationalen Entwicklungszusammenarbeit. In dieser Arbeit werden Machtstrukturen in zwei Fallstudien anhand der wissenssoziologischen Diskursanalyse untersucht; im Fokus steht dabei die entwickelte Methodologie. Die wissenssoziologische Diskursanalyse wird zur Studie der reziproken Beziehungen zwischen formellen und informellen sozialen Strukturen verwendet und in dieser Arbeit werden einige ansatzspezifische Stärken identifiziert und aufgeführt. Darüber hinaus wird diskutiert wie Strukturierung auf zwischenmenschlicher Ebene praktiziert wurde und wie diese existierende soziale Strukturen beeinflusst haben und vice versa. Die Studie belegt, dass die wissenssoziologische Diskursanalyse für Forschungsprojekte dieser Art geeignet ist.Power and knowledge are central concepts in the practice and analysis of international development. This study employs the Sociology of Knowledge Approach to Discourse Analysis (SKAD) to look at power structures in two case studies in international development. The developed methodology is the focus of this paper. SKAD’s insights into the circular relationship between informal and formalised social structures and the contribution SKAD can make in this domain are outlined. Furthermore, it is discussed how, in the open and invited spaces observed in the case studies, structuration was practically conducted and how this process was influenced by pre-existing institutional structures and vice versa. It was found that SKAD can support enquiries of this kind
Keep it simple: time-of-use tariffs in high-wind scenarios
Price signals have been suggested to bring about greater demand side flexibility and thus support the integration of variable sources of energy, such as wind. A conflict exists between keeping these signals simple for consumers, while making responses appropriate for increasingly complex supply–demand balancing dynamics in future. This study reviews some of the demand responses observed in time-of-use (ToU) tariff trials and assesses their effectiveness in scenarios with higher levels of wind. The authors simulate wholesale real-time prices for high-wind scenarios as a benchmark tariff. Simple tariff structures are compared against real-time prices for the extent to which they can ‘nudge’ demand in the ‘right direction’. They present results which suggest that even in high-wind scenarios, simple ToU tariffs could have a beneficial effect on overall system costs. The load shifting and reduction behaviour observed under ToU trials could lower energy costs by between 4 and 6% without the need for complex price signals
Research and practice: a critical reflection on approaches that underpin research into people's information behaviour
Purpose The purpose of this paper is to provide a critical discussion on the nature of research into people's information behaviour, and in particular the contribution of the phenomenological approach for the development of information solutions. Design/methodology/approach The approach takes the form of a conceptual analysis drawing on the research literature and personal research experience. Findings The paper brings to the foreground the relative value of different conceptual approaches and how these underpin and relate to the development of information solutions. Research limitations/implications The paper, due to the breadth and complexity of the subject, serves to highlight key issues and bringing together ideas. Some topics deserve further explanation. However, this was beyond the scope of this paper. Practical implications A conceptual framework is provided that indicates the value of the epistemic spectrum for information behaviour studies and provides support for action research and participative design. Social implications Taking a phenomenological approach, and consequently either a first person approach and/or a highly participative approach to research, challenges the relationship between researcher and respondent. It also raises questions about why the authors conduct research and for whom it is intended. Originality/value The paper makes explicit the underlying philosophical assumptions and how these ideas influence the way the authors conduct research; it highlights the significance of Cartesian dualism and indicates the significance of these assumptions for the development of information solutions. It supports the view that researchers and developers should be open to respondents leading the exploration of their needs
Open innovation in Health and Social Care: ICT supported co-creation of quality improvements
Open innovation in Health and Social Care: ICT supported co-creation of quality improvement
Research and practice A critical reflection on approaches that underpin research into people’s information behaviour
Purpose – The purpose of this paper is to provide a critical discussion on the nature of research into people's information behaviour, and in particular the contribution of the phenomenological approach for the development of information solutions. Design/methodology/approach – The approach takes the form of a conceptual analysis drawing on the research literature and personal research experience. Findings – The paper brings to the foreground the relative value of different conceptual approaches and how these underpin and relate to the development of information solutions. Research limitations/implications – The paper, due to the breadth and complexity of the subject, serves to highlight key issues and bringing together ideas. Some topics deserve further explanation. However, this was beyond the scope of this paper. Practical implications – A conceptual framework is provided that indicates the value of the epistemic spectrum for information behaviour studies and provides support for action research and participative design. Social implications – Taking a phenomenological approach, and consequently either a first person approach and/or a highly participative approach to research, challenges the relationship between researcher and respondent. It also raises questions about why the authors conduct research and for whom it is intended. Originality/value – The paper makes explicit the underlying philosophical assumptions and how these ideas influence the way the authors conduct research; it highlights the significance of Cartesian dualism and indicates the significance of these assumptions for the development of information solutions. It supports the view that researchers and developers should be open to respondents leading the exploration of their needs
Mediterranean countries' food consumption and sourcing patterns:An Ecological Footprint viewpoint
AbstractSecuring food for growing populations while minimizing environmental externalities is becoming a key topic in the current sustainability debate. This is particularly true in the Mediterranean region, which is characterized by scarce natural resources and increasing climate-related impacts.This paper focuses on the pressure Mediterranean people place on the Earth ecosystems because of their food consumption and sourcing patterns and then explores ways in which such pressure can be reduced. To do so, it uses an Ecological-Footprint-Extended Multi-Regional Input-Output (EF-MRIO) approach applied to 15 Mediterranean countries. Results indicate that food consumption is a substantial driver of the region's ecological deficit, whereby demand for renewable resources and ecosystems services outpaces the capacity of its ecosystems to provide them. Portugal, Malta and Greece are found to have the highest per capita food Footprints (1.50, 1.25 and 1.22 global hectares (gha), respectively), while Slovenia, Egypt and Israel have the lowest (0.63, 0.64 and 0.79gha, respectively). With the exception of France, all Mediterranean countries rely on the biocapacity of foreign countries to satisfy their residents' demand for food.By analyzing the effect of shifting to a calorie-adequate diet or changing dietary patterns, we finally point out that the region's Ecological Footprint – and therefore its ecological deficit – could be reduced by 8% to 10%
Defining the landscape of circular RNAs in neuroblastoma unveils a global suppressive function of MYCN
Circular RNAs (circRNAs) are a regulatory RNA class. While cancer-driving functions have been identified for single circRNAs, how they modulate gene expression in cancer is not well understood. We investigate circRNA expression in the pediatric malignancy, neuroblastoma, through deep whole-transcriptome sequencing in 104 primary neuroblastomas covering all risk groups. We demonstrate that MYCN amplification, which defines a subset of high-risk cases, causes globally suppressed circRNA biogenesis directly dependent on the DHX9 RNA helicase. We detect similar mechanisms in shaping circRNA expression in the pediatric cancer medulloblastoma implying a general MYCN effect. Comparisons to other cancers identify 25 circRNAs that are specifically upregulated in neuroblastoma, including circARID1A. Transcribed from the ARID1A tumor suppressor gene, circARID1A promotes cell growth and survival, mediated by direct interaction with the KHSRP RNA-binding protein. Our study highlights the importance of MYCN regulating circRNAs in cancer and identifies molecular mechanisms, which explain their contribution to neuroblastoma pathogenesis
Optimasi Portofolio Resiko Menggunakan Model Markowitz MVO Dikaitkan dengan Keterbatasan Manusia dalam Memprediksi Masa Depan dalam Perspektif Al-Qur`an
Risk portfolio on modern finance has become increasingly technical, requiring the use of sophisticated mathematical tools in both research and practice. Since companies cannot insure themselves completely against risk, as human incompetence in predicting the future precisely that written in Al-Quran surah Luqman verse 34, they have to manage it to yield an optimal portfolio. The objective here is to minimize the variance among all portfolios, or alternatively, to maximize expected return among all portfolios that has at least a certain expected return. Furthermore, this study focuses on optimizing risk portfolio so called Markowitz MVO (Mean-Variance Optimization). Some theoretical frameworks for analysis are arithmetic mean, geometric mean, variance, covariance, linear programming, and quadratic programming. Moreover, finding a minimum variance portfolio produces a convex quadratic programming, that is minimizing the objective function ðð¥with constraintsð ð 𥠥 ðandð´ð¥ = ð. The outcome of this research is the solution of optimal risk portofolio in some investments that could be finished smoothly using MATLAB R2007b software together with its graphic analysis
Differential cross section measurements for the production of a W boson in association with jets in proton–proton collisions at √s = 7 TeV
Measurements are reported of differential cross sections for the production of a W boson, which decays into a muon and a neutrino, in association with jets, as a function of several variables, including the transverse momenta (pT) and pseudorapidities of the four leading jets, the scalar sum of jet transverse momenta (HT), and the difference in azimuthal angle between the directions of each jet and the muon. The data sample of pp collisions at a centre-of-mass energy of 7 TeV was collected with the CMS detector at the LHC and corresponds to an integrated luminosity of 5.0 fb[superscript −1]. The measured cross sections are compared to predictions from Monte Carlo generators, MadGraph + pythia and sherpa, and to next-to-leading-order calculations from BlackHat + sherpa. The differential cross sections are found to be in agreement with the predictions, apart from the pT distributions of the leading jets at high pT values, the distributions of the HT at high-HT and low jet multiplicity, and the distribution of the difference in azimuthal angle between the leading jet and the muon at low values.United States. Dept. of EnergyNational Science Foundation (U.S.)Alfred P. Sloan Foundatio
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