Definition of the CAPRI Core Modelling System and Interfaces with other Components of SEAMLESS-IF

Environmental Economics and Policy,

Analysis of climate change impacts on EU agriculture by 2050

The 2013 EU strategy on adaptation to climate change aims at contributing to a more climate-resilient Europe. However, there are still large gaps in understanding and characterising climate impacts in Europe and how impacts in the rest of the world could affect Europe. This report provides quantitative modelling-based results from biophysical and agro-economic models as part of the PESETA-IV (Projection of Economic impacts of climate change in Sectors of the European Union based on bottom-up Analysis) project. We analyse climate change projections for 2050 considering the Representative Concentration Pathway (RCP) of 8.5 W/m2 (with corresponding global warming levels ranging between 1.6 oC and 2.7 oC compared to pre-industrial levels), as well as for 1.5 °C and 2 °C warming conditions. Results show that climate change will pose a threat to global food production in the medium to long term, and that Europe will also be affected. Forced by the projected changes in daily temperature, precipitation, wind, relative humidity, and global radiation, grain maize yields in the EU will decline between 1% and 22%. In addition, wheat yields in Southern Europe are expected to decrease by up to 49%. However, in Northern Europe some of the negative productivity effects caused by climate change may be partially offset by higher levels of atmospheric CO2 concentrations and changing precipitation regimes. Losses, especially in Southern Europe may be reduced by tailored adaptation strategies; e.g. changing varieties and crop types, increasing and improving irrigation practices for certain crops and when economically feasible. However, limitations on sustainable water abstraction levels could become a barrier to increase irrigation levels, specifically in the Mediterranean countries (particularly Spain, Portugal, Greece, Cyprus, Malta, Italy and Turkey) where duration of water scarcity under global warming are projected to intensify. As large negative climate change impacts on productivity outside of the EU are estimated, large market spill-over effects will push up production in both Northern and Southern Europe through higher demand for some agricultural commodities outside of EU, resulting in higher producer prices. This, in turn, may benefit farmers' income and have positive effects on the EU’s agricultural commodity exports. However, other limiting factors (not all fully integrated into the used modelling system yet), such as increasing water shortage in Southern Europe (Task 10) and constraints on the expansion of irrigation, increasing impacts of heatwaves and droughts, consequences of reduction of nutrient use due to environmental and climate mitigation constraints, need to be further evaluated.JRC.D.4-Economics of Agricultur

Plan de responsabilidad social empresarial Polylon S.A.

Anexo 1: Enlace del vídeo acerca del marketing social y corporativo, Anexo 2: PósterLa mayor parte de las investigaciones y estudios existentes en el ámbito de la responsabilidad social empresarial (RSE) se han dirigido a grandes empresas. El objetivo general de esta investigación es describir y analizar el conocimiento y las acciones de RSE a una empresa de menor tamaño, específicamente la empresa POLYLON S.A.; cuyo objetivo principal es el análisis de las acciones y prácticas de responsabilidad social en la empresa. Cada tema relacionado con la responsabilidad social fue visto y aplicado en el caso de la empresa POLYLON S.A., que en la cual fue diseñado el código de conducta donde aparecen los conflictos de interés y diferentes temas relacionados con la conducta de los trabajadores, identificados los Stakeholders quienes son los actores involucrados en la empresa y fue diseño tanto el plan de Responsabilidad Social Empresarial y el Plan de Comunicaciones donde en los fue explicado cómo participar en las tres dimensiones que son la Económica, Social y Ambiental.Most existing research and studies in the field of corporate social responsibility (CSR) have targeted large companies. The overall objective of this research is to describe and analyze the knowledge and actions of CSR to a smaller company, the company specifically POLYLON S.A.; whose main objective is to analyze the actions and practices of social responsibility in the company. Each issue related to social responsibility was seen and applied in the case of the company POLYLON SA, which was designed the code of conduct where conflicts of interest appear and different issues related to the behavior of workers, identified Stakeholders who are the actors involved in the company and was designed both the Corporate Social Responsibility plan and the Communications Plan where they were explained how to participate in the three dimensions that are Economic, Social and Environmental

Methodological concepts for integrated assessment of agricultural and environmental policies in SEAMLESS-IF

Agricultural and Food Policy, Environmental Economics and Policy, Farm Management, Land Economics/Use,

Shoc2/Sur8 protein regulates neurite outgrowth

This is an openaccess article distributed under the terms of the Creative Commons Attribution License.-- et al.The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasing the functional binding interaction between Ras and Raf, leading to increased ERK activity. Here we found that Shoc2 overexpression induced sustained ERK phosphorylation, notably in the case of EGF stimulation, and Shoc2 knockdown inhibited ERK activation. We demonstrate that ectopic overexpression of human Shoc2 in PC12 cells significantly promotes neurite extension in the presence of EGF, a stimulus that induces proliferation rather than differentiation in these cells. Finally, Shoc2 depletion reduces both NGF-induced neurite outgrowth and ERK activation in PC12 cells. Our data indicate that Shoc2 is essential to modulate the Ras-ERK signaling outcome in cell differentiation processes involved in neurite outgrowth.GL, TG and LMD were recipients of fellowships from the Ministerio de Educación y Ciencia (MEC) (to GL, TG), and Fondo de Investigaciones Sanitarias (FIS) (to LMD). LSR held a postdoctoral research contract from CIBERNED. This work was supported by FIS grant (PI10/00815) to JLO; CIBERNED to MC; SAF2008-01951, Comunidad Autónoma de Madrid (CAM) SSAL-0202-2006-01 and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) to TI; FIS grant PI12/00775 and ISCIII-RETIC (Red Temática de Investigación Cooperativa en Cáncer) RD12/0036/0027 from the Instituto de Salud Carlos III to PSG; and FIS grants (PI09/0562 and PI13/00703), ISCIIIRETIC (RD06/0020/0003 and RD12/0036/0021), and the Spanish Association Against Cancer (AECC) to JMR.Peer Reviewe

Shoc2/Sur8 Protein Regulates Neurite Outgrowth

The Shoc2 protein has been implicated in the positive regulation of the Ras-ERK pathway by increasing the functional binding interaction between Ras and Raf, leading to increased ERK activity. Here we found that Shoc2 overexpression induced sustained ERK phosphorylation, notably in the case of EGF stimulation, and Shoc2 knockdown inhibited ERK activation. We demonstrate that ectopic overexpression of human Shoc2 in PC12 cells significantly promotes neurite extension in the presence of EGF, a stimulus that induces proliferation rather than differentiation in these cells. Finally, Shoc2 depletion reduces both NGF-induced neurite outgrowth and ERK activation in PC12 cells. Our data indicate that Shoc2 is essential to modulate the Ras-ERK signaling outcome in cell differentiation processes involved in neurite outgrowth.This work was supported by FIS grant (PI10/00815) to JLO; CIBERNED to MC; SAF2008-01951, Comunidad Autónoma de Madrid (CAM) S-SAL-0202-2006-01 and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) to TI; FIS grant PI12/00775 and ISCIII-RETIC (Red Temática de Investigación Cooperativa en Cáncer) RD12/0036/0027 from the Instituto de Salud Carlos III to PSG; and FIS grants (PI09/0562 and PI13/00703), ISCIII-RETIC (RD06/0020/0003 and RD12/0036/0021), and the Spanish Association Against Cancer (AECC) to JMR. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.S

Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV

The performance of muon reconstruction, identification, and triggering in CMS has been studied using 40 inverse picobarns of data collected in pp collisions at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection criteria covering a wide range of physics analysis needs have been examined. For all considered selections, the efficiency to reconstruct and identify a muon with a transverse momentum pT larger than a few GeV is above 95% over the whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4, while the probability to misidentify a hadron as a muon is well below 1%. The efficiency to trigger on single muons with pT above a few GeV is higher than 90% over the full eta range, and typically substantially better. The overall momentum scale is measured to a precision of 0.2% with muons from Z decays. The transverse momentum resolution varies from 1% to 6% depending on pseudorapidity for muons with pT below 100 GeV and, using cosmic rays, it is shown to be better than 10% in the central region up to pT = 1 TeV. Observed distributions of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO

Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV

The performance of muon reconstruction, identification, and triggering in CMS has been studied using 40 inverse picobarns of data collected in pp collisions at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection criteria covering a wide range of physics analysis needs have been examined. For all considered selections, the efficiency to reconstruct and identify a muon with a transverse momentum pT larger than a few GeV is above 95% over the whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4, while the probability to misidentify a hadron as a muon is well below 1%. The efficiency to trigger on single muons with pT above a few GeV is higher than 90% over the full eta range, and typically substantially better. The overall momentum scale is measured to a precision of 0.2% with muons from Z decays. The transverse momentum resolution varies from 1% to 6% depending on pseudorapidity for muons with pT below 100 GeV and, using cosmic rays, it is shown to be better than 10% in the central region up to pT = 1 TeV. Observed distributions of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO

Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV

The azimuthal anisotropy of charged particles in PbPb collisions at nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS detector at the LHC over an extended transverse momentum (pt) range up to approximately 60 GeV. The data cover both the low-pt region associated with hydrodynamic flow phenomena and the high-pt region where the anisotropies may reflect the path-length dependence of parton energy loss in the created medium. The anisotropy parameter (v2) of the particles is extracted by correlating charged tracks with respect to the event-plane reconstructed by using the energy deposited in forward-angle calorimeters. For the six bins of collision centrality studied, spanning the range of 0-60% most-central events, the observed v2 values are found to first increase with pt, reaching a maximum around pt = 3 GeV, and then to gradually decrease to almost zero, with the decline persisting up to at least pt = 40 GeV over the full centrality range measured.Comment: Replaced with published version. Added journal reference and DO

Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy

A search for new physics is performed in events with two same-sign isolated leptons, hadronic jets, and missing transverse energy in the final state. The analysis is based on a data sample corresponding to an integrated luminosity of 4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of 7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of 140 increase in integrated luminosity over previously published results. The observed yields agree with the standard model predictions and thus no evidence for new physics is found. The observations are used to set upper limits on possible new physics contributions and to constrain supersymmetric models. To facilitate the interpretation of the data in a broader range of new physics scenarios, information on the event selection, detector response, and efficiencies is provided.Comment: Published in Physical Review Letter