Experimental validation of a drive-by stiffness identification method for bridge monitoring

 An experimental investigation is carried out to verify the feasibility of using an instrumented vehicle to detect and monitor bridge dynamic parameters. The low cost method consists of the use of a moving vehicle fitted with accelerometers on its axles. In the laboratory experiment, the vehicle-bridge interaction model consists of a scaled two-axle vehicle model crossing a simply supported steel beam. The bridge model also includes a scaled road surface profile. The effects of varying the vehicle model configuration and speed are investigated. A finite element beam model is calibrated using the experimental results and a novel algorithm for the identification of global bridge stiffness is validated. Using measured vehicle accelerations as input to the algorithm, the beam stiffness is identified with a reasonable degree of accuracy.European Commission - Seventh Framework Programme (FP7)Japanese Society for the Promotion of Science Postdoctoral Fellowship for North American and European ResearchersJapanese Society for the Promotion of Science Grant-in-Aid for Scientific Researc

Privacy-preserving Early Detection of Epileptic Seizures in Videos

In this work, we contribute towards the development of video-based epileptic seizure classification by introducing a novel framework (SETR-PKD), which could achieve privacy-preserved early detection of seizures in videos. Specifically, our framework has two significant components - (1) It is built upon optical flow features extracted from the video of a seizure, which encodes the seizure motion semiotics while preserving the privacy of the patient; (2) It utilizes a transformer based progressive knowledge distillation, where the knowledge is gradually distilled from networks trained on a longer portion of video samples to the ones which will operate on shorter portions. Thus, our proposed framework addresses the limitations of the current approaches which compromise the privacy of the patients by directly operating on the RGB video of a seizure as well as impede real-time detection of a seizure by utilizing the full video sample to make a prediction. Our SETR-PKD framework could detect tonic-clonic seizures (TCSs) in a privacy-preserving manner with an accuracy of 83.9% while they are only half-way into their progression. Our data and code is available at https://github.com/DevD1092/seizure-detectionComment: Accepted to MICCAI 202

A case report of COVID-19 monitoring in the Austrian professional football league

Since the beginning of the COVID -19 pandemic, many contact sport teams are facing major challenges to safely continue training and competition. We present the design and implementation of a structured monitoring concept for the Austrian national football league. 146 professional players from five clubs of the professional Austrian football league were monitored for a period of 12 weeks. Subjective health parameters, PCR- test results and data obtained from a geo-tracking app were collected. Simulations modelling the consequences of a COVID-19 case with increasing reproduction number were computed. No COVID -19 infection occurred during the observation period in the players. Infections in the nearer surroundings lead to increased perceived risk of infection. Geo tracking was particularly hindered due to technical problems and reluctance of users. Simulation models suggested a hypothetical shut-down of all training and competition activities. A structured monitoring concept can help to continue contact sports safely in times of a pandemic. Cooperation of all involved is essential. Trial registration: ID: DRKS00022166 15/6/2020 https://www.who.int/ictrp/search/en/

Teaching for the transition: The Canadian PGY-1 neurosurgery \u27rookie camp\u27

Background: Transitioning from medical school to residency is difficult and stressful, necessitating innovation in easing this transition. In response, a Canadian neurosurgical Rookie Camp was designed and implemented to foster acquisition of technical, cognitive and behavioral skills among incoming Canadian post graduate year one (PGY-1) neurosurgery residents. Methods: The inaugural Rookie Camp was held in July 2012 in Halifax. The curriculum was developed based on a national needs-assessment and consisted of a pre-course manual, 7 case-based stations, 4 procedural skills stations and 2 group discussions. The content was clinically focused, used a variety of teaching methods, and addressed multiple CanMEDS competencies. Evaluation included participant and faculty surveys and a pre-course, post-course, and 3-month retention knowledge test. Results: 17 of 23 PGY-1 Canadian neurosurgical residents participated in the Camp. All agreed the course content was relevant for PGY-1 training and the experience prepared them for residency. All participants would recommend the course to future neurosurgical residents. A statistically significant improvement was observed in knowledge related to course content (F(2,32) = 7.572, p\u3c0.002). There were no significant differences between post-test and retention-test scores at three months. Conclusion: The inaugural Canadian Neurosurgery Rookie Camp for PGY-1 residents was successfully delivered, with engagement from participants, training programs, the Canadian Neurosurgical Society, and the Royal College. In addition to providing fundamental knowledge, which was shown to be retained, the course eased junior residents\u27 transition to residency by fostering camaraderie and socialization within the specialty

Is resilience socially constructed? Empirical evidence from Fiji, Ghana, Sri Lanka, and Vietnam

The objective of this paper is to better understand the various individual and household factors that influence resilience, that is, people⬢s ability to respond adequately to shocks and stressors. One of our hypotheses is that resilience does not simply reflect the expected effects of quantifiable factors such as level of assets, or even less quantifiable social processes such as people⬢s experience, but is also determined by more subjective dimensions related to people⬢s perceptions of their ability to cope, adapt or transform in the face of adverse events. Data collected over two years in Fiji, Ghana, Sri Lanka and Vietnam confirms the importance of wealth in the recovery process of households affected by shocks and stressors. However our results challenge the idea that within communities, assets are a systematic differentiator in people⬢s response to adverse events. The findings regarding social capital are mixed and call for more research: social capital had a strong positive influence on resilience at the community level, yet our analysis failed to demonstrate any tangible positive correlation at the household level. Finally, the data confirm that, like vulnerability, resilience is at least in part socially constructed, endogenous to individual and groups, and hence contingent on knowledge, attitudes to risk, culture and subjectivity

The everyday world of bouncers: a rehabilitated role for covert ethnography

© 2018, The Author(s) 2018. The focus of this article is on the everyday world of bouncers in the night-time economy of Manchester, England. The structure of the article is to contextualise my covert passing in this demonized subculture followed by explorations of the everyday world of bouncers through the related concepts of door order and the bouncer self. A part of the article is an examination of the management of situated ‘ethical moments’ during the fieldwork and, more generally, critical reflections on emotionality, embodiment and risk-taking in ethnography. I also reflect on the retrospective and longitudinal nature of my fieldwork immersion, and both the data management challenges and possibilities this brings. Covert ethnography can be a creative part of the ethnographer’s tool kit and can provide an alternative perspective on subcultures, settings and organisations. By overly frowning upon the apparent ethical transgressions of covert research, we can stifle and censor the sociological imagination rather than enhance it. My call is for a rehabilitation of covert research

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Copy number variants (CNVs) have been strongly implicated in the genetic etiology of schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has been hampered by limited sample sizes. We sought to address this obstacle by applying a centralized analysis pipeline to a SCZ cohort of 21,094 cases and 20,227 controls. A global enrichment of CNV burden was observed in cases (OR=1.11, P=5.7×10−15), which persisted after excluding loci implicated in previous studies (OR=1.07, P=1.7 ×10−6). CNV burden was enriched for genes associated with synaptic function (OR = 1.68, P = 2.8 ×10−11) and neurobehavioral phenotypes in mouse (OR = 1.18, P= 7.3 ×10−5). Genome-wide significant evidence was obtained for eight loci, including 1q21.1, 2p16.3 (NRXN1), 3q29, 7q11.2, 15q13.3, distal 16p11.2, proximal 16p11.2 and 22q11.2. Suggestive support was found for eight additional candidate susceptibility and protective loci, which consisted predominantly of CNVs mediated by non-allelic homologous recombination

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyper-activity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. Genetic correlation analyses revealed a meaningful structure within the eight disorders, identifying three groups of inter-related disorders. Meta-analysis across these eight disorders detected 109 loci associated with at least two psychiatric disorders, including 23 loci with pleiotropic effects on four or more disorders and 11 loci with antagonistic effects on multiple disorders. The pleiotropic loci are located within genes that show heightened expression in the brain throughout the lifespan, beginning prenatally in the second trimester, and play prominent roles in neurodevelopmental processes. These findings have important implications for psychiatric nosology, drug development, and risk prediction.Peer reviewe