Kepercayaan Sebagai Salah Satu Faktor Kepuasan Kerja Untuk Mencapai Keberhasilan Proyek Perumahan

Penelitian ini bertujuan untuk mengetahui variabel yang paling dominan dalam membetuk kepercayaan diantara competence trust, integrity trust dan intuitive trust dan untuk mengetahui pengaruh hubungan kepercayaan terhadap kesuksesan proyek dengan menggunakan kepuasan kerjasama sebagai mediator. Populasi dalam penelitian ini adalah Perusahaan kontraktor yang telah mengerjakan atau menyelesaikan proyek di wilayah Surabaya. Sampel dalam penelitian ini berjumlah 40 responden, yang terdiri dari 23 owner (pemilik proyek) dan 17 orang kontraktor (pelaksana proyek). Analisis data dilakukan dengan bantuan software IBM SPSS 20 dan Smart PLS. Dari ketiga variabel yang membentuk variabel Trust (X), dapat disimpulkan bahwa model yang paling dominan dalam membentuk kepercayaan dalam pelaksanaan proyek adalah Integrity Trust, dengan mean loading factor sebesar 0,8402. Hasil penelitian ini juga menunjukkan bahwa Trust memiliki pengaruh yang positif signifikan terhadap Kesuksesan Proyek dengan menggunakan Kepuasan Kerjasama sebagai mediator, dimana koefisiensi pengaruh tidak langsung dari Trust ke Kepuasan Kepuasan Kerjasama dan ke Kesuksesan Proyek, yaitu sebesar 0,5745 (57,45%), lebih besar dibandingkan dengan pengaruh langsung dari Trust ke Kesuksesan Proyek, yaitu sebesar 0,3390 (33,90%)

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci.

Bone Mineral Density (BMD) is a highly heritable trait, but genome-wide association studies have identified few genetic risk factors. Epidemiological studies suggest associations between BMD and several traits and diseases, but the nature of the suggestive comorbidity is still unknown. We used a novel genetic pleiotropy-informed conditional False Discovery Rate (FDR) method to identify single nucleotide polymorphisms (SNPs) associated with BMD by leveraging cardiovascular disease (CVD) associated disorders and metabolic traits. By conditioning on SNPs associated with the CVD-related phenotypes, type 1 diabetes, type 2 diabetes, systolic blood pressure, diastolic blood pressure, high density lipoprotein, low density lipoprotein, triglycerides and waist hip ratio, we identified 65 novel independent BMD loci (26 with femoral neck BMD and 47 with lumbar spine BMD) at conditional FDR < 0.01. Many of the loci were confirmed in genetic expression studies. Genes validated at the mRNA levels were characteristic for the osteoblast/osteocyte lineage, Wnt signaling pathway and bone metabolism. The results provide new insight into genetic mechanisms of variability in BMD, and a better understanding of the genetic underpinnings of clinical comorbidity

Validation of the chinese version of the gambling related cognitions scale (GRCS-C)

Gambling cognitions have constantly been associated with the development and maintenance of problem gambling. Despite researchers reporting high rates of gambling and problem gambling among the Chinese, little is known about the role of gambling cognitions among Chinese individuals (Raylu & Oei, 2004a). This is partly because there is a lack of validated instruments to assess gambling cognitions in this population. Thus, the purpose of the present study was to examine and validate the Gambling Related Cognitions Scale-Chinese version (GRCS-C), which was based on the 23-item Gambling Related Cognitions Scale (GRCS; Raylu & Oei, 2004b). Confirmatory Factory Analysis (CFA) using 422 Chinese participants (166 Male, 256 Female; Mean age = 32.28 years) from the general community (221 living in Australia and 201 living in Taiwan) confirmed that a five-factor model was a good fit for the data. The Cronbach's alpha coefficient for the overall scale was .95, and ranged from .83 to .89 for the five factors. Concurrent, discriminant, and predictive validities of the GRCS (Chinese version) were also good suggesting that the GRCS-C is a valid and reliable instrument for assessing gambling cognitions among non-clinical Chinese samples