Bibliotheca antigua de los escritores aragoneses que florecieron desde la venida de Christo hasta el año 1500

Sign.: [ ]4, [asterisco]-2[asterisco]4, 3[asterisco]2, Aa-Zz4AntepLas h. de grab. calc., la primera es retrato de D. Felix de Latassa, entre port. y anteport. ; la segunda es escudo heráldico de D. Juan Martin de Goycoechea y Ciordia, a quien se dedica la obr

In Vitro Recording of Mesenteric Afferent Nerve Activity in Mouse Jejunal and Colonic Segments

Afferent nerves not only convey information concerning normal physiology, but also signal disturbed homeostasis and pathophysiological processes of the different organ systems from the periphery towards the central nervous system. As such, the increased activity or 'sensitization' of mesenteric afferent nerves has been allocated an important role in the pathophysiology of visceral hypersensitivity and abdominal pain syndromes. Mesenteric afferent nerve activity can be measured in vitro in an isolated intestinal segment that is mounted in a purpose-built organ bath and from which the splanchnic nerve is isolated, allowing researchers to directly assess nerve activity adjacent to the gastrointestinal segment. Activity can be recorded at baseline in standardized conditions, during distension of the segment or following the addition of pharmacological compounds delivered intraluminally or serosally. This technique allows the researcher to easily study the effect of drugs targeting the peripheral nervous system in control specimens; besides, it provides crucial information on how neuronal activity is altered during disease. It should be noted however that measuring afferent neuronal firing activity only constitutes one relay station in the complex neuronal signaling cascade, and researchers should bear in mind not to overlook neuronal activity at other levels (e.g., dorsal root ganglia, spinal cord or central nervous system) in order to fully elucidate the complex neuronal physiology in health and disease. Commonly used applications include the study of neuronal activity in response to the administration of lipopolysaccharide, and the study of afferent nerve activity in animal models of irritable bowel syndrome. In a more translational approach, the isolated mouse intestinal segment can be exposed to colonic supernatants from IBS patients. Furthermore, a modification of this technique has been recently shown to be applicable in human colonic specimens

In-pile loop irradiation studies of organic coolant materials : quarterly progress report, July 1-September 30, 1963

Statement of responsibility on title page reads: Report prepared by: E. A. Mason, Project Supervisor W. N. Bley, Project Engineer; Contributors: C. D. Sawyer A. H. Swan, R. A. Chin, J. P. Casey J. F. Terrien G. C. Nullens"Issued: December 15, 1963.""AEC Research and Development Report"--Cover"SRO-85."Includes bibliographical references (leaf 24)Quarterly progress report; July 1-September 30, 1963M.I.T. Project No. DSR 9819U.S. Atomic Energy Commission, Savannah River Operations Office Contract no. AT(38-1)-33

IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper

Correction: Volume14 Issue7 Article Number100557 DOI10.1016/j.waojou.2021.100557Currently, testing for immunoglobulin E (IgE) sensitization is the cornerstone of diagnostic evaluation in suspected allergic conditions. This review provides a thorough and updated critical appraisal of the most frequently used diagnostic tests, both in vivo and in vitro. It discusses skin tests, challenges, and serological and cellular in vitro tests, and provides an overview of indications, advantages and disadvantages of each in conditions such as respiratory, food, venom, drug, and occupational allergy. Skin prick testing remains the first line approach in most instances; the added value of serum specific IgE to whole allergen extracts or components, as well as the role of basophil activation tests, is evaluated. Unproven, non-validated, diagnostic tests are also discussed. Throughout the review, the reader must bear in mind the relevance of differentiating between sensitization and allergy; the latter entails not only allergic sensitization, but also clinically relevant symptoms triggered by the culprit allergen.Peer reviewe

Schriftgezag op het speelveld van de hermeneutische ethiek

Scripture on the playground of hermeneutical ethics. As a tribute to Jan G. van der Watt, in this article I offer a reflection on the authority of Scripture in ethics, in attempted loyalty to the motto of our theological faculty: Fides Quaerens Intellectum. The main thesis of this article is that ethics not only requires hermeneutics, but that the core task of ethics itself is interpretation. From an evangelical-reformed perspective, I will present a phenomenological and hermeneutical model, inspired by thinkers such as Gadamer and Ricoeur, defining ethics itself as a hermeneutical exercise, an act of interpretation, inherent to life itself. Defining ethics as such will influence the way in which we will integrate Scripture in our moral discourse. The playing field of hermeneutical Christian ethics is described by four points we will briefly discuss. Firstly, we will describe ethics as a philosophical and theological discipline with a hermeneutical task. Next, I offer three anchor points for the unique contribution of Scripture to this hermeneutical process: (1) faith as the entry point for interpreting Scripture as a source for Christian ethics; (2) the church in the world as the context in which one uses Scripture; and (3) in the Augustinian tradition, the double commandment of love as the ultimate rule of interpretation, the measure against which every text should be read. Despite the fact that these three anchor points all have their negative counterparts (idolatry, individualism and resentment), they are vital to the interpretation of Scripture in Christian ethics. Pastors who use Scripture for moral direction have to be aware of the characteristics of mora

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Are We Home Yet? : An Exploration of Queer Narratives of Forced Salvadoran Migrants

This thesis explores how LGBTQ*-Salvadoran applicants for international protection experience the influence of their own sexual orientation and gender identities in relation to the underlying motives behind their migration. In addition, it intends to draw some conclusions from the respondents' statements, gained insights from observations and what was found in literature. For this, two Salvadoran LGBTQ*- applicants for international protection, who applied for asylum in Belgium in the year 2019, were interviewed. Their discourses were analysed by using a thematic analysis.The study exposes the narratives and motivations which led them to flee their homeland and find a new life in Belgium

Are We Home Yet? : An Exploration of Queer Narratives of Forced Salvadoran Migrants

This thesis explores how LGBTQ*-Salvadoran applicants for international protection experience the influence of their own sexual orientation and gender identities in relation to the underlying motives behind their migration. In addition, it intends to draw some conclusions from the respondents' statements, gained insights from observations and what was found in literature. For this, two Salvadoran LGBTQ*- applicants for international protection, who applied for asylum in Belgium in the year 2019, were interviewed. Their discourses were analysed by using a thematic analysis.The study exposes the narratives and motivations which led them to flee their homeland and find a new life in Belgium