Hypothermic machine perfusion preservation after controlled donor cardiac death reduce delayed graft function

Introduction & Objectives: in Spain kidneys after controlled cardiac death (cDCD) has increased over the years. This group present a high incidence of DGF. Graft quality optimization has been the major interest over the last decade. The aim of this study is to evaluate de benefit of hypothermic machine perfusion (HMP) in reducing de delayed graft function (DGF) and primary non-function (PNF) compared to cold storage in cDCD. Other parameters are evaluated: 99mTc-MAG-3 scintigraphy TFS (tubular function slope) and ultrasound (US) resistive index (RI) 24-48 hours after surgery, rejection rate, duration of DGF. Materials & Methods: We are conducting a randomized prospective study since April 2017. We select all cDCD from one single institution, Hospital Universitari de Bellvitge, and we randomize 1:1 to cold storage and HMP. Data from donors, surgery, HMP, and post-operatory are collected; and analysed

Labour supply and employment in the euro area countries - developments and challenges

The aim of this report, which has been prepared by a Task Force of the Monetary Policy Committee of the Eurosystem, is to describe and analyse the main developments in labour supply and its determinants in the euro area, review the links between labour supply and labour market institutions, assess how well labour supply reflects the demand for labour in the euro area and identify the future challenges for policy-makers. The data available for this report generally cover the period from 1983 to spring 2007. JEL Classification: E5, J1, J2, J6.Labour supply, employment, participation, hours worked, immigration, skill and education, structural policies, labour demand, unemployment, euro area countries, labour markets, taxes and benefits, childcare, pensions, training, human capital, labour quality, working time and contracts, discrimination, mismatch, returns to education.

FONTES DE CONTAMINAÇÃO E CONTÁGIO DE PROTOTHECA ZOPFII EM PROPRIEDADE LEITEIRA

O trabalho teve como objetivo foi determinar fontes de contaminação e contágio de Prototheca zopfii em propriedade leiteira situada na cidade de Ribeirão do Pinhal, Estado do Paraná. Material e Métodos: foram coletadas 33 amostras com suabe estéril de diferentes locais relacionados à produção leiteira. As amostras foram imersas em meio líquido de infusão de cérebro e coração (BHI) e incubadas sob aerofilia em estufa à 37ºC por 24 horas. Após esse período foram repicadas em meio sólido de BHI adicionado a sangue ovino desfibrinado e novamente incubados nas mesmas condições por 48 a 96 horas. Também foram coletadas amostras de leite de dois animais suspeitos e foram processadas conforme método recomendado pelo National Mastitis Council. As análises positivas no crescimento microbiano, foram identificadas segundo as características macro e microscópicas bioquímicas e tintoriais. Resultados: a alga Prototheca zopfii apresentou-se em 31,4% das amostras, inclusive nas mãos dos responsáveis pela ordenha. Conclusão: esta pesquisa demonstra a importância de adotar manejo profilático para garantir higidez dos rebanhos e dos funcionários das propriedades leiteiras

Robotic4all project: Results of a hands-on robotic surgery training program

Objective: Although robotic surgery adoption and its indications are growing worldwide, for multiple factors, including costs, there is a lack of training and experience. Our aim was to study the impact of a robotic introduction training program on gesture performance, such as suturing, in robot-naive individuals. Methods: Using the DaVinci robot, a 2-hour program was based on virtual reality and anatomical model exercises. All participants performed 3 repetitions of virtual reality exercises on the virtual simulator, and then performed and were assessed on 2 tests, ie robot and laparoscopic training box. After the course, the participants were surveyed for this training program. Results: Twenty-seven residents and surgeons were enrolled in the training program. With only 2 hours of training, all of the participants were able to complete the training program, thus learning generic and specific skills in robotic surgery. In virtual reality exercise, the scores of the 3 exercises increased significantly with every repetition (p < 0.001) and the size of the increase was large. The completion time on the robot platform was 2.6 times faster (169.33 ± 28.28 s vs. 447.96 ± 156.55 s, p < 0.001) than that in the laparoscopic box, and the difference between both types of tests was large (p h 2 ¼ 0.797). The centralization and passage of the needle were significantly better on the robot platform (5 vs. 3, p < 0.001, r ¼ 0.47; 5 vs. 4, p < 0.001, r ¼ 0.59) than in the laparoscopic box. For the intracorporeal stitchþknot test, every participant was able to perform the exercise on the robot but only 85.2% (23/27) in the laparoscopic box. Twenty-one participants answered the survey, and 13 (61.9%) of them consid- ered robotic performance independent of laparoscopic experience. Conclusions: Surgeons are interested and seek training in robotic surgery. We implemented the first hands-on robotic surgery training program in Portugal and participants considered it was important and adequate for its purpose. All participants, even without robotic experience, learned quicker, performed better, faster and more precisely on the robot over laparoscopy

Multicentre, randomised, single-blind, parallel group trial to compare the effectiveness of a Holter for Parkinson's symptoms against other clinical monitoring methods: study protocol

Introduction In recent years, multiple studies have aimed to develop and validate portable technological devices capable of monitoring the motor complications of Parkinson's disease patients (Parkinson's Holter). The effectiveness of these monitoring devices for improving clinical control is not known. Methods and analysis This is a single-blind, cluster-randomised controlled clinical trial. Neurologists from Spanish health centres will be randomly assigned to one of three study arms (1:1:1): (a) therapeutic adjustment using information from a Parkinson?s Holter that will be worn by their patients for 7 days, (b) therapeutic adjustment using information from a diary of motor fluctuations that will be completed by their patients for 7 days and (c) therapeutic adjustment using clinical information collected during consultation. It is expected that 162 consecutive patients will be included over a period of 6 months. The primary outcome is the efficiency of the Parkinson?s Holter compared with traditional clinical practice in terms of Off time reduction with respect to the baseline (recorded through a diary of motor fluctuations, which will be completed by all patients). As secondary outcomes, changes in variables related to other motor complications (dyskinesia and freezing of gait), quality of life, autonomy in activities of daily living, adherence to the monitoring system and number of doctor?patient contacts will be analysed. The noninferiority of the Parkinson's Holter against the diary of motor fluctuations in terms of Off time reduction will be studied as the exploratory objective. Ethics and dissemination approval for this study has been obtained from the Hospital Universitari de Bellvitge Ethics Committee. The results of this study will inform the practical utility of the objective information provided by a Parkinson's Holter and, therefore, the convenience of adopting this technology in clinical practice and in future clinical trials. We expect public dissemination of the results in 2022.Funding This work is supported by AbbVie S.L.U, the Instituto de Salud Carlos III [DTS17/00195] and the European Fund for Regional Development, 'A way to make Europe'

Global data on earthworm abundance, biomass, diversity and corresponding environmental properties

14 p.Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ecological groups. This global dataset contains 10,840 sites, with 184 species, from 60 countries and all continents except Antarctica. The data were obtained from 182 published articles, published between 1973 and 2017, and 17 unpublished datasets. Amalgamating data into a single global database will assist researchers in investigating and answering a wide variety of pressing questions, for example, jointly assessing aboveground and belowground biodiversity distributions and drivers of biodiversity change

Global data on earthworm abundance, biomass, diversity and corresponding environmental properties

Publisher Copyright: © 2021, The Author(s).Earthworms are an important soil taxon as ecosystem engineers, providing a variety of crucial ecosystem functions and services. Little is known about their diversity and distribution at large spatial scales, despite the availability of considerable amounts of local-scale data. Earthworm diversity data, obtained from the primary literature or provided directly by authors, were collated with information on site locations, including coordinates, habitat cover, and soil properties. Datasets were required, at a minimum, to include abundance or biomass of earthworms at a site. Where possible, site-level species lists were included, as well as the abundance and biomass of individual species and ecological groups. This global dataset contains 10,840 sites, with 184 species, from 60 countries and all continents except Antarctica. The data were obtained from 182 published articles, published between 1973 and 2017, and 17 unpublished datasets. Amalgamating data into a single global database will assist researchers in investigating and answering a wide variety of pressing questions, for example, jointly assessing aboveground and belowground biodiversity distributions and drivers of biodiversity change.Peer reviewe