391 research outputs found
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Evaluation of WRF and HadRM Mesoscale Climate Simulations over the U.S. Pacific Northwest
This work compares the Weather Research and Forecasting (WRF) and Hadley Centre Regional Model (HadRM) simulations with the observed daily maximum and minimum temperature (Tmax and Tmin) and precipitation at Historical Climatology Network (HCN) stations over the U.S. Pacific Northwest for 2003–07. The WRF and HadRM runs were driven by the NCEP/Department of Energy (DOE) Atmospheric Model Intercomparison Project (AMIP)-II Reanalysis (R-2) data. The simulated Tmax in WRF and HadRM as well as in R-2 compares well with the observations. Predominantly cold biases of Tmax are noted in WRF and HadRM in spring and summer, while in winter and fall more stations show warm biases, especially in HadRM. Large cold biases of Tmax are noted in R-2 at all times. The simulated Tmin compares reasonably well with the observations, although not as well as Tmax in both models and in the reanalysis R-2. Warm biases of Tmin prevail in both model simulations, while R-2 shows mainly cold biases. The R-2 data play a role in the model biases of Tmax, although there are also clear indications of resolution dependency. The model biases of Tmin originate mainly from the regional models. The temporal correlation between the simulated and observed daily precipitation is relatively low in both models and in the reanalysis; however, the correlation increases steadily for longer averaging times. The high-resolution models perform better than R-2, although the nested WRF domains do have the largest biases in precipitation during the winter and spring seasonsKeywords: Mesoscale models, Temperature, North America, Climatolog
GCIP water and energy budget synthesis (WEBS)
As part of the World Climate Research Program\u27s (WCRPs) Global Energy and Water-Cycle Experiment (GEWEX) Continental-scale International Project (GCIP), a preliminary water and energy budget synthesis (WEBS) was developed for the period 1996–1999 from the “best available” observations and models. Besides this summary paper, a companion CD-ROM with more extensive discussion, figures, tables, and raw data is available to the interested researcher from the GEWEX project office, the GAPP project office, or the first author. An updated online version of the CD-ROM is also available at http://ecpc.ucsd.edu/gcip/webs.htm/. Observations cannot adequately characterize or “close” budgets since too many fundamental processes are missing. Models that properly represent the many complicated atmospheric and near-surface interactions are also required. This preliminary synthesis therefore included a representative global general circulation model, regional climate model, and a macroscale hydrologic model as well as a global reanalysis and a regional analysis. By the qualitative agreement among the models and available observations, it did appear that we now qualitatively understand water and energy budgets of the Mississippi River Basin. However, there is still much quantitative uncertainty. In that regard, there did appear to be a clear advantage to using a regional analysis over a global analysis or a regional simulation over a global simulation to describe the Mississippi River Basin water and energy budgets. There also appeared to be some advantage to using a macroscale hydrologic model for at least the surface water budgets
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[Arctic] Greenland ice sheet [in “State of the Climate in 2012”]
Melting at the surface of the Greenland Ice Sheet set new records for extent and melt index (i.e., the number of days on which melting occurred multiplied by the area where melting was detected) for the period 1979–2012, according to passive microwave observations (e.g., Tedesco 2007, 2009; Mote and Anderson 1995). Melt extent reached ~97% of the ice sheet surface during a rare, ice-sheet-wide event on 11–12 July (Fig. 5.13a; Nghiem et al. 2012). This was almost four times greater than the average melt extent for 1981–2010. The 2012 standardized melting index (SMI, defined as the melting index minus its average and divided by its standard deviation) was +2.4, almost twice the previous record of about +1.3 set in 2010
Progesterone action in human tissues: regulation by progesterone receptor (PR) isoform expression, nuclear positioning and coregulator expression
Progesterone is a critical regulator of normal female reproductive function, with diverse tissue-specific effects in the human. The effects of progesterone are mediated by its nuclear receptor (PR) that is expressed as two isoforms, PRA and PRB, which are virtually identical except that PRA lacks 164 amino acids that are present at the N-terminus of PRB. Considerable in vitro evidence suggests that the two PRs are functionally distinct and in animals, tissue-specific distribution patterns of PRA and PRB may account for some of the diversity of progesterone effects. In the human, PRA and PRB are equivalently expressed in most target cells, suggesting that alternative mechanisms control the diversity of progesterone actions. PR mediates the effects of progesterone by association with a range of coregulatory proteins and binding to specific target sequences in progesterone-regulated gene promoters. Ligand activation of PR results in redistribution into discrete subnuclear foci that are detectable by immunofluorescence, probably representing aggregates of multiple transcriptionally active PR-coregulator complexes. PR foci are aberrant in cancers, suggesting that the coregulator composition and number of complexes is altered. A large family of coregulators is now described and the range of proteins known to bind PR exceeds the complement required for transcriptional activation, suggesting that in the human, tissue-specific coregulator expression may modulate progesterone response. In this review, we examine the role of nuclear localization of PR, coregulator association and tissue-specific expression in modulating progesterone action in the human
A Limousin Specific Myostatin Allele Affects Longissimus Muscle Area and Fatty Acid Profiles in a Wagyu-Limousin F2 Population
A microsatellite-based genome scan of a Wagyu x Limousin F(2) cross population previously demonstrated QTL affecting LM area and fatty acid composition were present in regions near the centromere of BTA2. In this study, we used 70 SNP markers to examine the centromeric 24 megabases (Mb) of BTA2, including the Limousin-specific F94L myostatin allele (AB076403.1; 415C \u3e A) located at approximately 6 Mb on the draft genome sequence of BTA2. A significant effect of the F94L marker was observed (F = 60.17) for LM area, which indicated that myostatin is most likely responsible for the effect. This is consistent with previous reports that the substitution of Leu for Phe at AA 94 of myostatin (caused by the 415C \u3e A transversion) is associated with increased muscle growth. Surprisingly, several fatty acid trait QTL, which affected the amount of unsaturated fats, also mapped to or very near the myostatin marker, including the ratio of C16:1 MUFA to C16:0 saturated fat (F = 16.72), C18:1 to C18:0 (F = 18.88), and total content of MUFA (F = 17.12). In addition, QTL for extent of marbling (F = 14.73) approached significance (P = 0.05), and CLA concentration (F = 9.22) was marginally significant (P = 0.18). We also observed associations of SNP located at 16.3 Mb with KPH (F = 15.00) and for the amount of SFA (F = 12.01). These results provide insight into genetic differences between the Wagyu and Limousin breeds and may lead to a better tasting and healthier product for consumers through improved selection for lipid content of beef
Finding Water Scarcity Amid Abundance Using Human–Natural System Models
Water scarcity afflicts societies worldwide. Anticipating water shortages is vital because of water’s indispensable role in social-ecological systems. But the challenge is daunting due to heterogeneity, feedbacks, and water’s spatial-temporal sequencing throughout such systems. Regional system models with sufficient detail can help address this challenge. In our study, a detailed coupled human–natural system model of one such region identifies how climate change and socioeconomic growth will alter the availability and use of water in coming decades. Results demonstrate how water scarcity varies greatly across small distances and brief time periods, even in basins where water may be relatively abundant overall. Some of these results were unexpected and may appear counterintuitive to some observers. Key determinants of water scarcity are found to be the cost of transporting and storing water, society’s institutions that circumscribe human choices, and the opportunity cost of water when alternative uses compete
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An approach to designing a national climate service
Climate variability and change are considerably important for a wide range of human activities and natural ecosystems. Climate science has made major advances during the last two decades, yet climate information is neither routinely useful for nor used in planning. What is needed is a mechanism, a national climate service (NCS), to connect climate science to decision-relevant questions and support building capacity to anticipate, plan for, and adapt to climate fluctuations. This article contributes to the national debate for an NCS by describing the rationale for building an NCS, the functions and services it would provide, and how it should be designed and evaluated. The NCS is most effectively achieved as a federal interagency partnership with critically important participation by regional climate centers, state climatologists, the emerging National Integrated Drought Information System, and the National Oceanic and Atmospheric Administration (NOAA) Regional Integrated Sciences Assessment (RISA) teams in a sustained relationship with a wide variety of stakeholders. Because the NCS is a service, and because evidence indicates that the regional spatial scale is most important for delivering climate services, given subnational geographical/geophysical complexity, attention is focused on lessons learned from the University of Washington Climate Impacts Group's 10 years of experience, the first of the NOAA RISA teams.Keywords: Pacific Northwest climate, regional integrated sciences and assessment
Attribution of Declining Western U.S. Snowpack to Human Effects
Observations show snowpack has declined across much of the western United States over the period 1950–99. This reduction has important social and economic implications, as water retained in the snowpack from winter storms forms an important part of the hydrological cycle and water supply in the region. A formal model-based detection and attribution (D–A) study of these reductions is performed. The detection variable is the ratio of 1 April snow water equivalent (SWE) to water-year-to-date precipitation (P), chosen to reduce the effect of P variability on the results. Estimates of natural internal climate variability are obtained from 1600 years of two control simulations performed with fully coupled ocean–atmosphere climate models. Estimates of the SWE/P response to anthropogenic greenhouse gases, ozone, and some aerosols are taken from multiple-member ensembles of perturbation experiments run with two models. The D–A shows the observations and anthropogenically forced models have greater SWE/P reductions than can be explained by natural internal climate variability alone. Model-estimated effects of changes in solar and volcanic forcing likewise do not explain the SWE/P reductions. The mean model estimate is that about half of the SWE/P reductions observed in the west from 1950 to 1999 are the result of climate changes forced by anthropogenic greenhouse gases, ozone, and aerosols.Lawrence Livermore National Laboratory///Estados UnidosScripps Institution of Oceanography//SIO/Estados UnidosMinistry of Education, Culture, Sports, Science and Technology///JapónCalifornia Energy Commission///Estados UnidosProgram of Climate Model Diagnosis and Intercomparison/[DOE-W-7405-ENG-48]/PCMDI/Estados UnidosUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Básicas::Centro de Investigaciones Geofísicas (CIGEFI
The state of the Martian climate
60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes
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