41 research outputs found
The Problem of Experience in the Study of Organizations
This paper deals with the fact that we cannot experience large organizations directly, in the same way as we can experience individuals or small groups, and that this non-experientiability has certain implications for our scientific theories of organizations. Whereas a science is animated by a constructive interplay of theory concepts and experience concepts, the study of organizations has been confined to theory concepts alone. Implications of this analysis for developing a science of organizations are considered.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68303/2/10.1177_017084069301400102.pd
Effects of conventional feeds vs. table food waste on the quantitative and qualitative characteristics of pork
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Bibliography: leaves 126-132.Not availabl
Prevalence of multimorbidity in people with and without severe mental illness:a systematic review and meta-analysis
BACKGROUND: People with severe mental illness, such as schizophrenia-spectrum disorder and bipolar disorder, face poorer health outcomes from multiple chronic illnesses. Physical multimorbidity, the coexistence of two or more chronic physical conditions, and psychiatric multimorbidity, the coexistence of three or more psychiatric disorders, are both emerging concepts useful in conceptualising disease burden. However, the prevalence of physical and psychiatric multimorbidity in this cohort is unknown. This study aimed to estimate the absolute prevalence of both physical and psychiatric multimorbidity in people with severe mental illness, and also compare the odds of physical multimorbidity prevalence against people without severe mental illness.METHODS: We searched CINAHL, EMBASE, PubMed, and PsycINFO from inception until Feb 15, 2024, for observational studies that measured multimorbidity prevalence. To be included, studies had to have an observational study design, be conducted in an adult population (mean age ≥18 years) diagnosed with either schizophrenia-spectrum disorder or bipolar disorder, and include a measurement of occurrence of either physical multimorbidity (≥2 physical health conditions) or psychiatric multimorbidity (≥3 psychiatric conditions total, including the severe mental illness). From control studies, a random-effects meta-analysis compared odds of physical multimorbidity between people with and without severe mental illness. Absolute prevalence of physical and psychiatric multimorbidity in people with severe mental illness was also calculated. Sensitivity and meta-regression analyses tested an array of demographic, diagnostic, and methodological variables.FINDINGS: From 11 144 citations we included 82 observational studies featuring 1 623 773 individuals with severe mental illness (specifically schizophrenia-spectrum disorder or bipolar disorder), of which 21 studies featured 13 235 882 control individuals without severe mental illness (descriptive data for the entire pooled cohorts were not available for numbers of males and females, age, and ethnicity). This study did not feature involvement of people with lived experience. The odds ratio (OR) of physical multimorbidity between people with and without severe mental illness was 2·40 (95% CI 1·57-3·65, k=11, p=0·0009). This ratio was higher in younger severe mental illness populations (mean age ≤40 years, OR 3·99, 95% CI 1·43-11·10) compared with older populations (mean age >40 years, OR 1·55, 95% CI 0·96-2·51; subgroup differences p=0·0013). For absolute prevalence, 25% of those with severe mental illness have physical multimorbidity (95% CI 0·19-0·32, k=29) and 14% have psychiatric multimorbidity (95% CI 0·08-0·23, k=21).INTERPRETATION: This is the first meta-analysis to estimate physical alongside psychiatric multimorbidity prevalence, showing that these are common in people with schizophrenia-spectrum disorder and bipolar disorder. The greater burden of physical multimorbidity in people with severe mental illness compared with those without is higher for younger cohorts, reflecting a need for earlier intervention. Our findings speak to the utility of multimorbidity for characterising the disease burden associated with severe mental illness, and the importance of facilitating integrated physical and mental health care.FUNDING: None.</p
Use and Outcomes of Noninvasive Ventilation for Acute Respiratory Failure in Different Age Groups
BACKGROUND: The prevalence of chronic disease and do-not-intubate status increases with age. Thus, we aimed to determine characteristics and outcomes associated with noninvasive ventilation (NIV) use for acute respiratory failure (ARF) in different age groups. METHODS: A database comprising prospective data collected on site on all adult patients with ARF requiring ventilatory support from 8 acute care hospitals in Massachusetts was used. RESULTS: From a total of 1,225 ventilator starts, overall NIV utilization, success, and in-hospital mortality rates were 22, 54, and 18% in younger (18-44 y); 34, 65, and 13% in middle-aged (45-64 y); 49, 68, and 17% in elderly (65-79 y); and 47, 76, and 24% in aged (>= 80 y) groups, respectively (P = 65 y than in those < 65 y, especially for subjects with cardiogenic pulmonary edema. However, NIV success and mortality rates were similar between age groups
Automated Ultrafiltration Device for Environmental Nanoparticle Research and Implications: A Review
Nanoparticle research and development have brought significant breakthroughs in many areas of basic and applied sciences. However, efficiently collecting nanoparticles in large quantities in pure and natural systems is a major challenge in nanoscience. This review article has focused on experimental investigation and implications of nanoparticles in soil, clay, geological and environmental sciences. An automated ultrafiltration device (AUD) apparatus was used to demonstrate efficient collection and separation of nanoparticles in highly weathering red soils, black soils, and gouge of earthquake fault, as well as zeolite. The kaolinite, illite, goethite, and hematite were identified in highly weathering red soils. Transmission electron microscopic (TEM) images showed the presence of hematite nanoparticles on the surface coating of kaolinite nanoparticles and aggregated hematite nanoparticles overlapping the edge of a kaolinite flake in a size range from 4 to 7 nm. The maximum crystal violet (CV) and methylene blue (MB) adsorption amount of smectite nanoparticles (<100 nm) separated by black soils were about two to three times higher than those of bulk sample (<2000 nm). The smectite nanoparticles adsorb both CV and MB dyes efficiently and could be employed as a low-cost alternative to remove cationic dyes in wastewater treatment. Quartz grain of <50 nm was found in the gouge of fault by X-ray diffraction (XRD) analysis and TEM observation. Separated quartz could be used as the index mineral associated with earthquake fracture and the finest grain size was around 25 nm. Comparing the various particle-size fractions of zeolite showed significant differences in surface area, Si to Al molar ratio, morphology, crystallinity, framework structure, and surface atomic structure of nanoparticles from those of the bulk sample prior to particle-size fractionations. The AUD apparatus has the characteristics of automation, easy operation, and high efficiency in the separation of nanoparticles and would, thus, facilitate future nanoparticle research and developments in basic and applied sciences
Dual-mode recognition of biogenic amine tryptamine and fluoride ions by a naphthyl hydrazone platform: application in fluorescence imaging of HeLa cells and zebrafish embryos
The performance of the CMS muon detector in proton-proton collisions at √s = 7 TeV at the LHC
The performance of all subsystems of the CMS muon detector has been studied by using a sample of proton-proton collision data at √s = 7 TeV collected at the LHC in 2010 that corresponds to an integrated luminosity of approximately 40 pb-1. The measured distributions of the major operational parameters of the drift tube (DT), cathode strip chamber (CSC), and resistive plate chamber (RPC) systems met the design specifications. The spatial resolution per chamber was 80–120 μm in the DTs, 40–150 μm in the CSCs, and 0.8–1.2 cm in the RPCs. The time resolution achievable was 3 ns or better per chamber for all 3 systems. The efficiency for reconstructing hits and track segments originating from muons traversing the muon chambers was in the range 95–98%. The CSC and DT systems provided muon track segments for the CMS trigger with over 96% efficiency, and identified the correct triggering bunch crossing in over 99.5% of such events. The measured performance is well reproduced by Monte Carlo simulation of the muon system down to the level of individual channel response. The results confirm the high efficiency of the muon system, the robustness of the design against hardware failures, and its effectiveness in the discrimination of backgrounds