Crop conditional Convolutional Neural Networks for massive multi-crop plant disease classification over cell phone acquired images taken on real field conditions

Convolutional Neural Networks (CNN) have demonstrated their capabilities on the agronomical field, especially for plant visual symptoms assessment. As these models grow both in the number of training images and in the number of supported crops and diseases, there exist the dichotomy of (1) generating smaller models for specific crop or, (2) to generate a unique multi-crop model in a much more complex task (especially at early disease stages) but with the benefit of the entire multiple crop image dataset variability to enrich image feature description learning. In this work we first introduce a challenging dataset of more than one hundred-thousand images taken by cell phone in real field wild conditions. This dataset contains almost equally distributed disease stages of seventeen diseases and five crops (wheat, barley, corn, rice and rape-seed) where several diseases can be present on the same picture. When applying existing state of the art deep neural network methods to validate the two hypothesised approaches, we obtained a balanced accuracy (BAC=0.92) when generating the smaller crop specific models and a balanced accuracy (BAC=0.93) when generating a single multi-crop model. In this work, we propose three different CNN architectures that incorporate contextual non-image meta-data such as crop information onto an image based Convolutional Neural Network. This combines the advantages of simultaneously learning from the entire multi-crop dataset while reducing the complexity of the disease classification tasks. The crop-conditional plant disease classification network that incorporates the contextual information by concatenation at the embedding vector level obtains a balanced accuracy of 0.98 improving all previous methods and removing 71% of the miss-classifications of the former methods

Genetic influences on schizophrenia and subcortical brain volumes:Large-scale proof of concept

Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between people with schizophrenia and healthy individuals. As common genetic associations are emerging for both schizophrenia and brain imaging phenotypes, we can now use genome-wide data to investigate genetic overlap. Here we integrated results from common variant studies of schizophrenia (33,636 cases, 43,008 controls) and volumes of several (mainly subcortical) brain structures (11,840 subjects). We did not find evidence of genetic overlap between schizophrenia risk and subcortical volume measures either at the level of common variant genetic architecture or for single genetic markers. These results provide a proof of concept (albeit based on a limited set of structural brain measures) and define a roadmap for future studies investigating the genetic covariance between structural or functional brain phenotypes and risk for psychiatric disorders