Visión estratégica de la Armada de Chile y de su relación con Argentina

Exposición realizada por el Comandante en Jefe de la Armada en la Academia de Guerra de la Armada Argentina,  octubre de 200

RhoA–ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells

The active vitamin D metabolite 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) inhibits proliferation and promotes differentiation of colon cancer cells through the activation of vitamin D receptor (VDR), a transcription factor of the nuclear receptor superfamily. Additionally, 1,25(OH)2D3 has several nongenomic effects of uncertain relevance. We show that 1,25(OH)2D3 induces a transcription-independent Ca2+ influx and activation of RhoA–Rho-associated coiled kinase (ROCK). This requires VDR and is followed by activation of the p38 mitogen-activated protein kinase (p38MAPK) and mitogen- and stress-activated kinase 1 (MSK1). As shown by the use of chemical inhibitors, dominant-negative mutants and small interfering RNA, RhoA–ROCK, and p38MAPK-MSK1 activation is necessary for the induction of CDH1/E-cadherin, CYP24, and other genes and of an adhesive phenotype by 1,25(OH)2D3. RhoA–ROCK and MSK1 are also required for the inhibition of Wnt–β-catenin pathway and cell proliferation. Thus, the action of 1,25(OH)2D3 on colon carcinoma cells depends on the dual action of VDR as a transcription factor and a nongenomic activator of RhoA–ROCK and p38MAPK-MSK1

GlobTherm, a global database on thermal tolerances for aquatic and terrestrial organisms

CITATION: Bennett, J. M., et al. 2018. GlobTherm, a global database on thermal tolerances for aquatic and terrestrial organisms. Scientific Data, 5:180022, doi:10.1038/sdata.2018.22.The original publication is available at https://www.nature.comHow climate affects species distributions is a longstanding question receiving renewed interest owing to the need to predict the impacts of global warming on biodiversity. Is climate change forcing species to live near their critical thermal limits? Are these limits likely to change through natural selection? These and other important questions can be addressed with models relating geographical distributions of species with climate data, but inferences made with these models are highly contingent on non-climatic factors such as biotic interactions. Improved understanding of climate change effects on species will require extensive analysis of thermal physiological traits, but such data are both scarce and scattered. To overcome current limitations, we created the GlobTherm database. The database contains experimentally derived species’ thermal tolerance data currently comprising over 2,000 species of terrestrial, freshwater, intertidal and marine multicellular algae, plants, fungi, and animals. The GlobTherm database will be maintained and curated by iDiv with the aim to keep expanding it, and enable further investigations on the effects of climate on the distribution of life on Earth.https://www.nature.com/articles/sdata201822Publisher's versio

GlobTherm, a global database on thermal tolerances for aquatic and terrestrial organisms

This database includes thermal tolerance metrics for 2,133 species of multicellular algae, plants, fungi, and animals in 43 classes, 203 orders and 525 families from both aquatic, and terrestrial realms, extracted from published studies. Abbreviated citations are included in the 'REF_min' and 'REF_max' variable in the data file. For full citations, please see the attached workbook, "References_1_09_2017.xlsx". The data are available in both Excel and CSV formats in the Dryad Digital Repository (doi:10.5061/dryad.1cv08). Updates to the data and metadata will be curated through the iDiv data portal (https://idata.idiv.de/). For example, in the future we plan to include interspecific variation in the dataset, to provide multiple estimates of thermal tolerance limits for a given species where estimates determined using the best possible methods will be more highly ranked

Personal body ornamentation on the Southern Iberian Meseta: An archaeomineralogical study

Beads and pendants from the Castillejo del Bonete (Terrinches, Ciudad Real) and Cerro Ortega (Villanueva de la Fuente, Ciudad Real) burials were analysed using XRD, micro-Raman and XRF in order to contribute to the current distribution map of green bead body ornament pieces on the Iberian Peninsula which, so far, remain undetailed for many regions. XRD, micro-Raman and XRF analyses showed that most of the beads from Castillejo del Bonete (Late 3rd millennium cal. BC) were made from variscite or green phyllosilicates, while Cerro Ortega's (Late 4th millenniumcal. BC) beads were made out of fossil wood or Clinochlore. Significantly enough,while XRD pointed to variscite as the main crystallo-graphic phase, the elemental composition did not match any elemental compositions of known and characterised sources, thus suggesting an unknown south-eastern source or an extra-peninsular origin of these ornamental pieces

Impacto de los procesos de acreditación: “caso faciatec-comeaa”

El estudio se condujo en Chihuahua, Chihuahua. Se diseñó un cuestionario para analizar los impactos más destacables que han tenido los procesos de acreditación en el área agropecuaria, específicamente en  la  Facultad  de  Ciencias  Agrotecnológicas,  obtenido  desde  la  percepción  de  las  personas  que lideraron o participaron en los procesos de autoevaluación y acreditación (el personal docente) aportando un grado de validez. La población de estudio fue de 10 docentes de tiempo completo y de hora clase que pertenecen a las carreras de Licenciatura en Administración Agrotecnológica, Ingeniero en Producción y Comercialización Hortícola e Ingeniero en Desarrollo Territorial

Classification of strengthening exercises of the lower member posterior chain, based on the amplitude of muscular activation in amateur soccer players between 18-25 years

The hamstring injuries are recurrent in the sports disciplines of teams such as football, with rehabilitation being a key point to prevent future alterations. Within this process, the strengthening paradigms are rather empirical, therefore, criteria based on the exercises used are required. In this context, the objective of the present investigation is to classify the strengthening exercises of the posterior lower limb chain, based on the amplitude of muscular activation, in amateur soccer players of the Andrés Bello University (UNAB), for which a non-experimental, descriptive, cross-sectional design. The study population was 30 university students, who were studying from first to fifth year, during the academic period 2017. The participants were summoned to the Laboratory of Rehabilitation Sciences, where after signing the informed consent they had to perform a phase of heating on a cycle ergometer, then the MCIV (maximum voluntary isometric contraction) of the semimembranous, semitendinous, biceps femoral and gluteus maximus muscles was calculated, finally applying a battery of strengthening exercises, which were classified according to the intensity of muscle activation. In relation to this, it was obtained that 8 of the 13 exercises implemented were classified as low intensity (p <0.05), 3 of medium intensity (p <0.05) and 2 of high intensity (p <0.05), while the peak of amplitude of the semimembranous, semitendinous and biceps femoral muscles moved to the right in temporal terms, to the extent that the exercises classified as low, medium and high intensity are compared.Las lesiones de isquiotibiales son recurrentes en disciplinas deportivas de equipos como el fútbol, siendo la rehabilitación un punto clave para prevenir alteraciones futuras. Dentro de este proceso, los paradigmas de fortalecimiento son más bien empíricos, por lo tanto, criterios fundamentados en torno a los ejercicios utilizados son requeridos. Bajo este contexto, el objetivo de la presente investigación fue clasificar los ejercicios de fortalecimiento de la cadena posterior de miembro inferior, en base a la amplitud de activación muscular, en futbolistas amateur de la Universidad Andrés Bello (UNAB), para lo cual se utilizó un diseño no experimental de tipo descriptivo y de corte transversal. La población de estudio, fueron 30 estudiantes universitarios, que estaban cursando de primero a quinto año, durante el periodo académico 2017. Los participantes fueron citados al Laboratorio de Ciencias de Rehabilitación de la UNAB, en donde luego de firmar el consentimiento informado debieron realizar una fase de calentamiento en cicloergómetro, posteriormente se calculó la MCIV (Máxima contracción isométrica voluntaria) de los músculos semimembranoso, semitendinoso, bíceps femoral y glúteo mayor, para finalmente aplicar una batería de ejercicios de fortalecimientos, los cuales fueron clasificados según la intensidad de activación muscular. En relación con esto, se obtuvo que 8 de los 13 ejercicios implementados fueron clasificados de baja intensidad (p<0.05), 3 de mediana intensidad (p<0.05) y 2 de alta intensidad (p<0.05), mientras que el peak de amplitud de los músculos semimembranoso, semitendinoso y bíceps femoral se desplazó a la derecha en términos temporales, en la medida que se comparan los ejercicios clasificados como de baja, media y alta intensidad

Pedagogía Ignaciana 5. Reflexiones para un modelo educativo universitario ignaciano

Obra que reúne las ponencias presentadas en el Seminario Internacional sobre el Modelo Ignaciano Universitario, realizado en el Instituto Tecnológico y de Estudios Superiores de Occidente, del 16 al 18 de febrero de 1998. Allí se abordaron cuestiones sobre la tradición educativa de los jesuitas, los elementos esenciales de un modelo universitario de inspiración ignaciana y su praxis.ITESO, A.C