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Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
Ahn J. H.
Aiken T.
Aime A.
Ajlan A.
Akalin M.
Akaydin E.
Akeel N.
Akgor U.
Akhtar M. A.
Akhter Rahman M. M.
Akilli H.
Akin E.
Akkour K.
Akmenkalne L.
Al Abdallah M.
Al Awwad S.
Al Habes H.
Al Maadany F. S.
Al Raddadi R.
Al-Habib A.
Al-Habsi R.
Al-Ishaq Z.
Al-Khayal K.
Al-Masri M.
Al-Mohammad A.
Al-Mukhtar A.
Al-Najjar H.
Al-Omishy H.
Al-Sarireh B.
AL-Sayed M.
Al-Tamimi Y.
Alaa S.
AlAamer O.
Aladeojebi A.
Alam F.
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Alanbuki A.
Alatar A.
Alawneh F.
Alazawi D.
Albertsmeier M.
Albi Martin B.
Alburakan A.
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Publication venue: 'American Society of Clinical Oncology (ASCO)'
Publication date: 01/01/2021
Field of study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Archivio istituzionale della Ricerca - Università degli Studi di Parma

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

Author: Aawsaj Y.
Abad Gurumeta A.
Abad-Motos A.
Abate E.
Abatini C.
Abbadessa F.
Abbas A. M.
Abbassi-Ghadi N.
Abbott D.
Abbott T.
Abd Elazeem H. A. S.
Abdalla M.
Abdallah M.
Abdel Al S.
Abdel Jalil R.
Abdeldayem H.
Abdelkader Salama I.
Abdelkarem M. M.
Abdelkarim M.
Abdelmajeed A.
Abdelrahman A.
Abdelrahman S.
Abdelsamed A.
Abdou M.
Abdulkareem A.
Abdulwahed E.
Abdur-Rahman L.
Abel M. K.
Abellan M.
Aboelkassem Ibrahim A.
Abosamak N. E.
Abou Chaar M. K.
Abou-Khalil J.
Abouassi A.
Aboulkassem H.
Abreu Da Silva A.
Abu J.
Abu Za'nouneh F. J.
Abu-Nayla I.
Abubakar A.
Acebes Garcia F.
Achalandabaso Boira M.
Acher A.
Acrich E.
Adamina M.
Adamoli L.
Addae-Boateng E.
Aderombi A.
Adeyeye A.
Adiamah A.
Adishesh M.
Agapov M.
Aggarwal A.
Aghayeva A.
Agilinko J.
Agnes A.
Agostini C.
Agoston P.
Agrawal A.
Agresta F.
Aguado H.
Aguilar Gonzalez M.
Aguzzoli L.
Ahad S.
Ahmadi N.
Ahmeidat A.
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Ajlan A.
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Akeel N.
Akgor U.
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Akhter Rahman M. M.
Akilli H.
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Yurttas C.
Zacharoulis D.
Zafar S. N.
Zakai D.
Zakaria A. D.
Zakaria R.
Zakaria Z.
Zambelli M. F.
Zambon M.
Zamora L.
Zamvar V.
Zani S.
Zanotti S.
Zanus G.
Zapardiel I.
Zarabini A. G.
Zatecky J.
Zegarac M.
Zelic M.
Zeller N.
Zengin A. K.
Zerbib P.
Zervas K.
Zese M.
Zhang H.
Zivanovic M.
Zivkovic M.
Zizzo M.
Zografos C.
Zonta S.
Zorrilla Ortuzar J.
Zourntou S.
Zouzoulas D.
Zubaidi A.
Zullo A.
Publication venue: J Clin Oncol
Publication date: 01/01/2020
Field of study

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

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Institutional Research Information System University of Turin

Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study

Author: Abbott T.
Abbott T. E. F.
Abdallah M.
Abdelkarem M. M.
Abdulkareem A.
Abellan M.
Abou Chaar M. K.
Abouassi A.
Abur P. P.
Achalandabaso B. M.
Adamina M.
Adamoli L.
Ademuyiwa A. O.
Agarwal A.
Aguilera Lorena M.
Ahad S.
Akeel N.
Al H. H.
Al-Masri M.
Al-Najjar H.
Alakaloko F.
Alameer E.
Alawneh F.
Albertsmeiers M.
Alcaide M. F.
Alderson D.
Alexoudi V.
Alfaro-Goldaracena A.
Alhassan B.
Alhefdhi A.
Alintoprak F.
Alkarak S.
Allison J.
Almasri M.
Almeida A.
Alomair A.
Alonso-Lamberti L.
Alotaibi N.
Alqannas M.
Alresaini F.
Alsaif A.
Alsalamah R.
Alsaraireh O.
Alser O.
Alshaar M.
Alshahrani M.
Alsharif F.
Alshryda S.
Alsobhi S.
Alvarez M. R.
Alyami M.
Alzamanan M.
Ameerally P.
Ansarin M.
Antic S.
Antoniades K.
Anula R.
Anwar S.
Aoun S. G.
Arnaud A. P.
Arrangoiz R.
Ashcroft J.
Astreidis I.
Augestad K. M.
Ayasra F.
Ayub B.
Azam M.
Azevedo J.
Baietti A. M.
Balercia P.
Ballouhey Q.
Ban V. S.
Bandovas J. P.
Bankhead-Kendall B. K.
Barbier L.
Barlow E.
Barrabe A.
Barry C. P.
Batjer H. H.
Batstone M.
Batstone M.
Batstone M.
Bayhan Z.
Beasley N.
Becerra Garcia F. C.
Beech N.
Bekheit M.
Bellanti L.
Beltramini G. A.
Benkabbou A.
Benson R. A.
Benson R. A.
Bergonzani M.
Bertelli G.
Bertoli G.
Bescos C.
Beswick D.
Bettoni J.
Betz C. S.
Bewarder J.
Bhangu A.
Bhangu A.
Biasini M.
Bissolotti G.
Blanco-Colino R.
Boccalatte L. A.
Boeck M.
Bokhari A.
Borges N.
Bottcher A.
Boucher S.
Bowden J.
Brana I.
Brar A.
Breda D.
Breen K. A.
Breheret R.
Breik O.
Bretherton C.
Brown L.
Buarque I. L.
Buerba G. A.
Burg S.
Burgan D.
Burgess C.
Burke J.
Busch C. J.
Bussu F.
Buta M.
Bywater E.
Caimari B.
Caja V. P.
Callanan D.
Campisi G.
Cano-Valderrama O.
Cao H.
Capoglu R.
Carabias A.
Carrasco P. M.
Caruana E. J.
Caruso J.
Catarzi L.
Cavaleiro S.
Cayetano P. L.
Chaar M.
Chai A. K. W.
Chakrabortee S.
Chan C.
Chaudhry D.
Chew D.
Chidambaram S.
Chiesa-Estomba C. M.
Choudhry A.
Christensen P.
Christidis P.
Chu F.
Chumbinho B.
Cicconi S.
Cicconi S.
Cipriani R.
Citgez B.
Colak E.
Colao G. L.
Colino M.
Collard B.
Comini L. V.
Consorti G.
Cope D.
Cordera F.
Cordova A.
Correia S.
Cotoia A.
Coughlin P.
Cox D.
Cukier M.
Cunha M. F.
Cvetkovic A.
Cymes W.
D'Angelo G.
Dafnios N.
Dakpe S.
Davidson G. H.
Davies R. J.
Dawe N.
Dawson B. E.
De Barros J.
De Berardinis R.
De Bree R.
De Cicco R.
De Gea Rico A.
De La Cruz Monroy M. F. I.
De Oliveira Lopez A. L.
De Pablo Garcia-Cuenca A.
De Virgilio A.
Del Campo Martin M.
Deligiannidis D.
Demirli Atici S.
Desai A.
Devauchelle B.
Di Martino M.
Diez-Valladares L.
Djurisic I.
Dominguez I.
Drake T. M.
Dunderovic D.
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Duran-Valles F.
Durrani A. J.
Edmond M.
Edwards J. G.
Egan R. J.
Egoroff N.
El-Sayed I. H.
Elawad A.
Elhadi M.
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Emile S.
Enjuto D.
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Evans J. P.
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Fasanmade K.
Faustino A.
Fernandes V.
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Ferraz I.
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Figari M. F.
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Fiore M.
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Firat N.
Fitzgerald C.
Fitzgerald J. E.
Flavin M.
Fleming J.
Ford S.
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Fullmer T.
Fusetti S.
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Gallo G.
Galvao D.
Ganly I.
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Garcia A. M.
Garcia Perez J. M.
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Griffiths E. A.
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Hannah A.
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Heaton C. M.
Henry A.
Heras A. J.
Heritage E.
Hernandez Bartolome M. A.
Hisham I.
Ho M. W. S.
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Holzle F.
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Howe D.
Huang L.
Humphries S.
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Ibrahim A.
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Inic Z.
Ioannidis O.
Ionescu A.
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Jariod Ferrer U. M.
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Jenkinson M. D.
Jenny H.
Jevric M.
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Jimenez T. M.
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Jones C. S.
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Jonker P.
Jotic A.
Kaafarani H. M. A.
Kahn A.
Kalaitsidou I.
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Kam da Silva Andrade A.
Kamarajah S. K.
Kanatas A.
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Kauffmann P.
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Kinsella J.
Kiong K.
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Kleeff J.
Knight A.
Knitschke M.
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Koenig D.
Kolias A.
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Ladd M. R.
Laloze J.
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Larranaga J. J.
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Lau K.
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Lawani I.
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Lederhuber H.
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Li E.
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Loehrer A.
Loffler M. W.
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Marco G. A.
Maremonti P.
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Markose G.
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Marson E. J.
Marta Madolo M.
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Martin T.
Martinez Alonso J. A.
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Martorell P.
Marwan H.
Marx W.
Mashat A.
Mashbari H. N.
Masterson L.
Mastrilli F.
Mate P.
Mazingi D.
McCaul J.
McDermott F. D.
McDonald C.
McEwen R.
McGrath N.
Mckay S. C.
McLean K. A.
McLennan A.
McMahon J.
McNaught C.
Mehdi M.
Mellor C.
Mendes J. R.
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Messias J.
Metallidis S.
Michailidou D.
Michalski C.
Mihai R.
Milanovic M.
Millan A.
Mills E. C.
Milovanovic J.
Milutinovic V.
Minaya-Bravo A.
Minaya-Bravo A.
Miranda P.
Mockelmann N.
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Mohan H. M.
Moore R.
Mora-Guzman I.
Moro A.
Moss J.
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Muguerza J. M.
Munoz de Nova J. L.
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Mykula R.
Nageh M. A.
Nankivell P.
Nankivell P.
Nankivell P. C.
Nardi C.
Naredla P.
Nepogodiev D.
Nepogodiev D.
Neri F.
Ng-Kamstra J. S.
Niquen M.
Notte F.
Nouh T.
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Ntirenganya F.
Nunez-Garcia B.
Obeidat K.
Ofner D.
Ojha S.
Oktseloglou V.
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Oliveira J. M.
Olivos M.
Omar O.
Ortega V. I.
Osman N.
Osorio A.
Othman E.
Oussama K.
Outani O.
Ovaitt A.
Pajic S.
Pamias J.
Paraskevopoulos K.
Parkins K.
Parmar S.
Parreno-Sacdalanm M. D.
Pata F.
Patel A.
Paunovic I.
Pejnovic L.
Pellino G.
Pereira Rodrigues A.
Perera E.
Pergolini I.
Perra T.
Petrovic M.
Phung D.
Piazza C.
Picardo A. L.
Picciochi M.
Pietrobon G.
Pigadas N.
Pignataro L.
Pignatti M.
Pina S.
Pingarron-Martin L.
Pinkney T. D.
Pinto V.
Piras A.
Pizarro M. J.
Pockney P.
Poli T.
Politis S.
Popovic F.
Porcu A.
Posadas-Trujillo O. E.
Potter P.
Powell J.
Prabhu S.
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Rajgor A. D.
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Roslani A. C.
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Serralta de Colsa D.
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Silveira H.
Silveira N. I.
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Simoes J. F. F.
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Simoes J. F. F.
Simon C.
Simon C.
Simon Sanz M. V.
Singh A.
Singh R.
Singh S.
Sinha D.
Sistiaga-Suarez J. A.
Skoulakis C.
Slijepcevic N.
Smeets R.
Smolka W.
Snee D.
Sohrabi C.
Song J.
Soreide K.
Sosa M. V.
Souadka A.
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Speth U.
Spinelli A.
Spriano G.
Spurnic I.
Stavroglou A.
Steel B.
Stevic D.
Stewart G. D.
Sumrak S.
Sund M.
Sund M.
Sundar S.
Tabiri S.
Tagliabue M.
Talwar R.
Tanal M.
Tatsis D.
Taylor E. H.
Teixeira M.
Testelin S.
Thiruchelvam J.
Thole S.
Thomas E.
Thompson A.
Thompson D.
Tilaveridis I.
Timon C.
Tiwari A.
Toia F.
Tolani M. A.
Torres A.
Torretta S.
Tousidonis M.
Townend P.
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Trivic A.
Troncoso P. P.
Trout I. M.
Tsai L.
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Usseglio J.
Uyanik M. S.
Vahtsevanos K.
Valle Rubio A.
van der Plas W.
van Ramshorst G. H.
Varazzani A.
Varley I.
Velagapudi S.
Venetis G.
Venn M. L.
Vervoort D.
Vidya R.
Vieira A.
Vimalachandran D.
Vo U. G.
Vollkommer T.
Vovola F.
Vucic N.
Vujanac V.
Wai K. C.
Walker C.
Walker D.
Walton G.
Warren O. J.
Waseem S.
Wedderburn D.
Wensley F.
Wilkin R. J. W.
Williams T.
Winnand P.
Winter S. C.
Winter S. C.
Winter S. C.
Wolfer S.
Wright N.
Xu M. J.
Yesantharao P.
Ying Y.
Zakai D.
Zarabini A. G.
Zeller N.
Publication venue: 'Wiley'
Publication date: 01/01/2021
Field of study

Background: The aims of this study were to provide data on the safety of head and neck cancer surgery currently being undertaken during the coronavirus disease 2019 (COVID-19) pandemic. Methods: This international, observational cohort study comprised 1137 consecutive patients with head and neck cancer undergoing primary surgery with curative intent in 26 countries. Factors associated with severe pulmonary complications in COVID-19–positive patients and infections in the surgical team were determined by univariate analysis. Results: Among the 1137 patients, the commonest sites were the oral cavity (38%) and the thyroid (21%). For oropharynx and larynx tumors, nonsurgical therapy was favored in most cases. There was evidence of surgical de-escalation of neck management and reconstruction. Overall 30-day mortality was 1.2%. Twenty-nine patients (3%) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within 30 days of surgery; 13 of these patients (44.8%) developed severe respiratory complications, and 3.51 (10.3%) died. There were significant correlations with an advanced tumor stage and admission to critical care. Members of the surgical team tested positive within 30 days of surgery in 40 cases (3%). There were significant associations with operations in which the patients also tested positive for SARS-CoV-2 within 30 days, with a high community incidence of SARS-CoV-2, with screened patients, with oral tumor sites, and with tracheostomy. Conclusions: Head and neck cancer surgery in the COVID-19 era appears safe even when surgery is prolonged and complex. The overlap in COVID-19 between patients and members of the surgical team raises the suspicion of failures in cross-infection measures or the use of personal protective equipment. Lay Summary: Head and neck surgery is safe for patients during the coronavirus disease 2019 pandemic even when it is lengthy and complex. This is significant because concerns over patient safety raised in many guidelines appear not to be reflected by outcomes, even for those who have other serious illnesses or require complex reconstructions. Patients subjected to suboptimal or nonstandard treatments should be carefully followed up to optimize their cancer outcomes. The overlap between patients and surgeons testing positive for severe acute respiratory syndrome coronavirus 2 is notable and emphasizes the need for fastidious cross-infection controls and effective personal protective equipment

Archivio istituzionale della Ricerca - Università degli Studi di Parma

PubliCatt

Archivio Istituzionale della Ricerca- Università degli Studi di Foggia

Delaying surgery for patients with a previous SARS-CoV-2 infection

Author: A A Ali Karar
A A Kerawala
A A Marra
A Abad Gurumeta
A Abad-Motos
A Abdelmajeed
A Abdelrahman
A Abdelsamed
A Abdulkareem
A Aboelkassem Ibrahim
A Abouassi
A Abreu da Silva
A Abubakar
A Acher
A Aderombi
A Adeyeye
A Adiamah
A Aggarwal
A Aghayeva
A Agnes
A Agrawal
A Ahmeidat
A Aimé
A Ajlan
A Al-Habib
A Al-Mohammad
A Al-Mukhtar
A Aladeojebi
A Alamri
A Alanbuki
A Alatar
A Alburakan
A Alfaro-Goldaracena
A Alhamed
A Alhefdhi
A Almeciga
A Almeida
A Alomair
A Alonso Poza
A Alsaif
A Anastasi
A Antic
A Anzak
A Aprile
A Arminio
A Arulanantham
A Askari
A Asqalan
A Athanasiou
A Ayhan
A Ayman
A Ayubi
A Azizi
A B Martins
A Bacon
A Baker
A Balakrishnan
A Bandiera
A Banerjee
A Barrabe
A Beamish
A Bellacci
A Belli
A Belvedere
A Benkabbou
A Bhalla
A Bhangu
A Billè
A Bin Nasser
A Biondi
A Blatt
A Blazquez Martin
A Boddy
A Bokhari
A Bondurri
A Boulton
A Boutall
A Branquinho
A Brunelli
A Brunt
A Bruscino
A Budacan
A Burahee
A Böttcher
A C Almeida
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Alex Wilkins
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Ana Minaya-Bravo
Ana Minaya-Bravo
Ana Minaya-Bravo
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Anant Desai
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Andrew Knight
Andrew Loehrer
Andrew Schache
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Aneel A Bhangu
Aneel Bhangu
Angelos Kolias
Angelos Kolias
Anna Fagotti
Antonino Spinelli
Antonio Ramos-De la Medina
April C Roslani
Arda Isik
Arnav Agarwal
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Chai Akw
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O Alaamer
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U Akgor
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Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

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Head and neck cancer surgery during the COVID-19 pandemic: An international, multicenter, observational cohort study

Author: Abbott T
Abbott Tom EF
Abdallah M
Abdelkarem MM
Abdulkareem A
Abellán M
Abou Chaar MK
Abouassi A
Abur PP
Achalandabaso Boira M
Adamina Michel
Adamoli L
Ademuyiwa Adesoji O
Agarwal Arnav
Aguilera Lorena Maria
Ahad S
Akeel N
Al Habes H
Al-Masri M
Al-Najjar H
Alakaloko Felix
Alameer Ehab
Alawneh F
Albertsmeiers Markus
Alcaide Matas F
Alderson Derek
Alexoudi V
Alfaro-Goldaracena A
Alhassan B
Alhefdhi A
Alintoprak F
Alkarak S
Allison J
Almasri M
Almeida A
Alomair A
Alonso-Lamberti L
Alotaibi N
Alqannas M
Alresaini F
Alsaif A
Alsalamah R
Alsaraireh O
Alser Osaid
Alshaar Muhammad
Alshahrani M
Alsharif F
Alshryda Sattar
Alsobhi S
Alvarez MR
Alyami M
Alzamanan M
Ameerally P
Ansarin M
Antic S
Antoniades K
Anula R
Anwar S
Aoun SG
Arnaud Alexis P
Arrangoiz R
Ashcroft J
Astreidis I
Augestad Knut Magne
Ayasra Faris
Ayub B
Azam M
Azevedo José
Baietti AM
Balercia P
Ballouhey Q
Ban VS
Bandovas JP
Bankhead-Kendall Brittany K
Barbier L
Barlow Emma
Barrabe A
Barry CP
Batjer HH
Batstone M
Batstone Martin
Batstone Martin
Bayhan Z
Beasley N
Becerra García FC
Beech N
Bekheit M
Bellanti L
Beltramini GA
Benkabbou A
Benson Ruth A
Benson Ruth A
Bergonzani M
Bertelli G
Bertoli G
Bescós C
Beswick D
Bettoni J
Betz CS
Bewarder J
Bhangu Aneel
Bhangu Aneel
Biasini M
Bissolotti G
Blanco-Colino Ruth
Boccalatte LA
Boeck M
Bokhari A
Borges N
Boucher S
Bowden J
Brana I
Brar Amanpreet
Breda D
Breen Kerry A
Breheret R
Breik O
Bretherton Chris
Brown L
Buarque Igor Lima
Buerba GA
Burg S
Burgan D
Burgess C
Burke Joshua
Busch CJ
Bussu F
Buta M
Bywater Edward
Böttcher A
Caimari B
Caja Vivancos P
Callanan D
Campisi G
Cano-Valderrama O
Cao H
Carabias A
Carrasco Prats M
Caruana Edward J
Caruso J
Catarzi L
Cavaleiro S
Cayetano Paniagua L
Chaar Mohammad
Chai AKW
Chakrabortee Sohini
Chan C
Chaudhry Daoud
Chew D
Chidambaram S
Chiesa-Estomba CM
Choudhry A
Christensen Peter
Christidis P
Chu F
Chumbinho B
Cicconi Silvia
Cicconi Silvia
Cipriani R
Citgez B
Colao García L
Colino M
Collard B
Comini LV
Consorti G
Cope D
Cordera F
Cordova A
Correia S
Cotoia A
Coughlin P
Cox Daniel
Cukier Moises
Cunha Miguel F
Cvetkovic A
Cymes W
D'Angelo G
Dafnios N
Dakpé S
Davidson Giana H
Davies RJ
Dawe N
Dawson Brett E
De Barros J
De Berardinis R
De Bree R
De Cicco R
De Gea Rico A
De La Cruz Monroy MFI
De Oliveira López AL
De Pablo García-Cuenca A
De Virgilio A
Del Campo Martín M
Deligiannidis D
Demirli Atıcı S
Desai Anant
Devauchelle B
Di Martino M
Djurisic I
Domínguez I
Drake Thomas M
Dunne N
Dunđerović D
Duran-Valles F
Durrani AJ
Díez-Valladares L
Edmond M
Edwards John G
Egan RJ
Egoroff N
El-Sayed IH
Elawad A
Elhadi Muhammed
Elhusseini M
Elliott M
Emile Sameh
Enjuto D
Eskander M
Espino Segura-Illa M
Espinosa CA
Espitalier F
Etchill E
Ethunandan M
Evans Jonathan P
Faria CS
Farik Shebani
Farsi A
Fasanmade K
Faustino A
Fernandes V
Fernández M
Fernández Rodríguez P
Ferraz I
Ferreli F
Ferron C
Figari MF
Figueiredo de Barros I
Fiore M
Fiore Marco
Firat N
Fitzgerald C
Fitzgerald J Edward
Flavin M
Fleming J
Ford Samuel
Frade S
Franza M
Fraser L
Freitas A
Fu H
Fullmer T
Fusetti S
Fuson A
Gabre-Kidan A
Gacic S
Gaino F
Gallo Gaetano
Galvão D
Ganly I
Ganly Ian
Ganly Ian
Garcia-Sancho Tellez L
García Pérez JM
García Alonso M
García Romero E
García-Quijada J
Garmanova Tatiana
Garrido R
Garrido S
Gasparini G
Gatti A
Geddes A
Ghazali N
Ghosh Dhruv
Ghufoor K
Gianni' A
Giannini L
Gibson D
Gigliotti J
Gill C
Giménez Francés C
Giralt López de Sagredo J
Gkrinia E
Glasbey James
Glasbey James
Glasbey James C
Glasbey James C
Goddard J
Gomes Gustavo Mendonça Ataíde
Gomes J
González García JÁ
Goran M
Gordini L
Gore S
Gosau M
Graystone J
Grecinos Gustavo
Green L
Griffiths Ewen A
Grivas T
Gross N
Gründl Madalegna
Gueutier A
Gujjuri Rohan R
Gális B
Gómez Díaz CJ
Gómez Fernández L
Gómez Latorre L
Gómez-Pedraza A
Gönüllü E
Ha PK
Habeeb A
Hajiioannou J
Halkias Constantine
Halliday E
Hannah A
Hardie C
Hardie J
Harries R
Harrison Ewen M
Hassan N
Heaton CM
Henry A
Heras Aznar J
Heritage Emily
Hernandez Bartolome MA
Hisham Intisar
Ho Michael Wing Sung
Ho Michael WS
Ho MWS
Houston R
Howe D
Huang L
Humphries S
Hutchinson Peter J
Hwang Shelley
Hölzle F
Ibrahim A
Idle M
Inic Z
Ioannidis O
Ionescu A
Irune E
Isik Arda
Jackson Richard
Jackson Richard
Jariod Ferrer UM
Jeftic N
Jelovac D
Jenkinson Michael D
Jenny H
Jevric M
Jezdic Z
Jimenez Toscano M
Jimenez V
Jokic V
Jones Conor S
Jones T
Jonker Pascal
Jotic A
Kaafarani Haytham MA
Kahn A
Kalaitsidou I
Kalavrezos N
Kam da Silva Andrade A
Kamarajah Sivesh K
Kanatas A
Kang C
Kauffmann P
Kaya T
Keatley James M
Kent A
Khatkar H
Khatri Chetan
Khaw Rachel A
Kiconco H
King E
Kinsella J
Kiong K
Kittur M
Kleeff J
Knight Andrew
Knitschke M
Kocer B
Koenig D
Kolias Angelos
Konstantinovic V
Korais C
Kornblith L
Kotlar B
Koukoura O
Kovacevic B
Krdzic I
Kruijff Schelto
Kucuk GO
Kulkarni G
Kumar A
Kuzmanovic C
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Ladd MR
Laloze J
Lami M
Lanfranco D
Larrañaga JJ
Larruscain E
Lau K
Lavagen N
Lawani Ismail
Lawday Samuel
Lazić M
Lederhuber Hans
Lee RH
Lemma F
Lennon P
Lester S
Leventoglu Sezai
Li Elizabeth
Li Z
Liew YT
Lin DJ
Liokatis P
Litvin Andrey
Lizzi V
Loehrer Andrew
Loh C
Lombardi CP
Long C
Lorencin M
Lorenz K
Lott N
Loubani M
Loutzidou L
Louvrier A
Lozano Lominchar P
Luke L
Luksic I
Lázaro A
Löffler Markus W
M. elghazaly S
Macina S
Magalhães Maia M
Mahasin Z
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Maimbo Mayaba
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Major Piotr
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Malapati H
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Manickavasagam J
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Markose G
Markovic I
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Marta Madolo Maria
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Martin Janet
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Mastrilli F
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Mazingi Dennis
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McDonald C
McEwen R
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Mckay Siobhan C
McLean Kenneth A
McLennan A
McMahon J
McNaught C
Mehdi M
Mellor C
Mendes JR
Mercado MÁ
Mercante G
Messias J
Metallidis Symeon
Michailidou D
Michalski C
Mihai R
Milanović M
Millan A
Mills Emily C
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Milutinović V
Minaya-Bravo Ana
Minaya-Bravo Ana
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Mohan Helen M
Moore Rachel
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Oliva R
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Rajgor AD
Ramos-De la Medina Antonio
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Redondo Calvo FJ
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Reinhard T
Rey Biel Juan
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Rivera Carlos Jose Perez
Rizzo D
Roberts Keith
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Rutegård Martin
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Saratziotis A
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Saverio Salomone Di
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Serralta de Colsa D
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Seyi-Olajide Justina O
Shahine M
Sharma N
Sharma Neil
Shaw R
Shaw Richard
Shaw Richard
Shaw Richard
Shaw S
Sheahan P
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Sholadoye TT
Shu Sebastian
Siaw-Acheampong Kwabena
Silva N
Silva P
Silveira H
Silveira Nunes I
Simoes Joana FF
Simoes Joana FF
Simoes Joana FF
Simon Christian
Simon Christian
Simón Sanz MV
Singh A
Singh R
Singh S
Sinha D
Sistiaga-Suárez JA
Skoulakis C
Slijepcevic N
Smeets R
Smolka W
Snee D
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Song J
Soreide Kjetil
Sosa MV
Souadka A
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Spriano G
Spurnic I
Stavroglou A
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Stewart Grant D
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Sundar Sudha
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Tabiri Stephen
Tagliabue M
Talwar R
Tanal M
Tatsis D
Taylor Elliott H
Teixeira M
Testelin S
Thiruchelvam J
Thole S
Thomas E
Thompson A
Thompson D
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Timon C
Tiwari Abhinav
Toia F
Tolani MA
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Townend Philip
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Vahtsevanos K
Valle Rubio A
van der Plas Willemijn
van Ramshorst Gabrielle H
Varazzani A
Varley I
Velagapudi S
Venetis G
Venn Mary L
Vervoort D
Vidya Raghavan
Vieira A
Vimalachandran Dale
Vo UG
Vollkommer T
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Waseem S
Wedderburn Duane
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Wilkin Richard JW
Williams T
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Winter SC
Winter Stuart C
Winter Stuart C
Wolfer S
Wright Naomi
Xu MJ
Yesantharao P
Ying Y
Zakai D
Zarabini AG
Zeller N
Çapoğlu R
Çolak E
Öfner D
Šimko K
Publication venue: 'Wiley'
Publication date: 01/01/2020
Field of study

University of Liverpool Repository

Serveur académique lausannois

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Oxford University Research Archive

Queen Mary Research Online

University of Dundee Online Publications

White Rose Research Online

Archivio istituzionale della ricerca - Università di Modena e Reggio Emilia

University of Melbourne Institutional Repository

Archivio istituzionale della ricerca - Università di Padova

Archivio istituzionale della ricerca - Università di Palermo

Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic.

Author: Aawsaj Y
Abad Gurumeta A
Abad-Motos A
Abate E
Abatini C
Abbadessa F
Abbas AM
Abbassi-Ghadi N
Abbott D
Abbott T
Abbott TEF
Abd Elazeem HAS
Abdalla M
Abdallah M
Abdelaal SA
Abdeldayem H
Abdelkarem MM
Abdelkarim M
Abdelmajeed A
Abdelrahman A
Abdelrahman S
Abdelsamed A
Abdou M
Abdulkareem A
Abdulwahed E
Abdur-Rahman L
Abel MK
Abellan M
Abosamak NE
Abou Chaar MK
Abou-Khalil J
Abouassi A
Aboulkassem H
Abreu da Silva A
Abu Za'nouneh FJ
Abu J
Abu-Nayla I
Abubakar A
Abukhalaf S
Acebes Garcia F
Achalandabaso Boira M
Acher A
Acrich E
Adamina M
Adamina M
Adamoli L
Addae-Boateng E
Ademuyiwa AO
Aderombi A
Adeyeye A
Adiamah A
Adishesh M
Agapov M
Agarwal A
Aggarwal A
Aghayeva A
Agilinko J
Agnes A
Agostini C
Agoston P
Agrawal A
Agresta F
Aguado H
Aguzzoli L
Ahad S
Ahmadi N
Ahmed NR
Ahmeidat A
Ahn JH
Aiken T
Aime A
Ajlan A
Akalin M
Akaydin E
Akeel N
Akgor U
Akhtar MA
Akilli H
Akin E
Akkour K
Akkulak M
Akmenkalne L
Al Abdallah M
Al Abdel S
Al Awwad S
Al Habes H
Al Maadany FS
Al Raddadi R
AL Sayed M
Al-Habib A
Al-Habsi R
Al-Ishaq Z
Al-Khayal K
Al-Masri M
Al-Mohammad A
Al-mukhtar A
Al-Najjar H
Al-omishy H
Al-Sarireh B
Al-Tamimi Y
Alaa S
AlAamer O
Aladeojebi A
Alakaloko F
Alam F
Alam N
Alam R
Alameer E
Alamri A
Alamri A
Alanbuki A
Alatar A
Alawneh F
Alazawi D
Albertsmeier M
Albertsmeiers M
Albi Martin B
Alburakan A
Alcaide Matas F
Alconchel F
Aldayri Z
Aldecoa Ansorregui I
Alderson D
Aldokali N
Aleksic L
Alemanno G
Alexoudi V
Alfaro-Goldaracena A
Alfieri S
Alga A
Alghamdi M
Alhalal H
Alhamed A
Alharthi M
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Alhassan B
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Alhefdhi A
Ali AK
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Aljanadi F
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Alkadeeki GZ
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Allemand C
Allison J
Almalik O
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Almeciga A
Almeida A
Almeida AC
Almeida JI
Almgla N
Almond M
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Alonso Poza A
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Altintoprak F
Alurralde C
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Amaral MJ
Ameerally P
Amira G
Amonkar S
Amorim E
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Angelo M
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Annessi V
Ansarin M
Anthoulakis C
Antic A
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de Solorzano Aurusa OFJ
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Fernandez Pablos FJ
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Ferraz I
Ferreira Pinto AP
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Figueiredo de Barros I
Findlay L
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Garcia-Quijada J
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Gavalda Pellice MGP
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Gkrinia E
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Glasbey JC
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GlobalSurg
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Gonzalez-Nicolas Trebol MT
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Gracia-Roche C
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Zarabini AG
Zatecky J
Zegarac M
Zelic M
Zeller N
Zengin AK
Zerbib P
Zervas K
Zese M
Zhang H
Zivanovic M
Zivkovic M
Zizzo M
Zografos C
Zonta S
Zorrilla Ortuzar J
Zourntou S
Zouzoulas D
Zubaidi A
Zullo A
Publication venue: Br J Surg
Publication date: 11/11/2020
Field of study

BACKGROUND: Surgical services are preparing to scale up in areas affected by COVID-19. This study aimed to evaluate the association between preoperative SARS-CoV-2 testing and postoperative pulmonary complications in patients undergoing elective cancer surgery. METHODS: This international cohort study included adult patients undergoing elective surgery for cancer in areas affected by SARS-CoV-2 up to 19 April 2020. Patients suspected of SARS-CoV-2 infection before operation were excluded. The primary outcome measure was postoperative pulmonary complications at 30 days after surgery. Preoperative testing strategies were adjusted for confounding using mixed-effects models. RESULTS: Of 8784 patients (432 hospitals, 53 countries), 2303 patients (26.2 per cent) underwent preoperative testing: 1458 (16.6 per cent) had a swab test, 521 (5.9 per cent) CT only, and 324 (3.7 per cent) swab and CT. Pulmonary complications occurred in 3.9 per cent, whereas SARS-CoV-2 infection was confirmed in 2.6 per cent. After risk adjustment, having at least one negative preoperative nasopharyngeal swab test (adjusted odds ratio 0.68, 95 per cent confidence interval 0.68 to 0.98; P = 0.040) was associated with a lower rate of pulmonary complications. Swab testing was beneficial before major surgery and in areas with a high 14-day SARS-CoV-2 case notification rate, but not before minor surgery or in low-risk areas. To prevent one pulmonary complication, the number needed to swab test before major or minor surgery was 18 and 48 respectively in high-risk areas, and 73 and 387 in low-risk areas. CONCLUSION: Preoperative nasopharyngeal swab testing was beneficial before major surgery and in high SARS-CoV-2 risk areas. There was no proven benefit of swab testing before minor surgery in low-risk areas

Ezid

Crossref

AIR Universita degli studi di Milano

UCL Discovery

eScholarship - University of California

Archivio istituzionale della ricerca - Alma Mater Studiorum Università di Bologna

Apollo (Cambridge)

Bern Open Repository and Information System (BORIS)

Queen Mary Research Online

White Rose Research Online

Archivio istituzionale della ricerca - Università di Palermo

Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

Author: Aawsaj Y
Abad Gurumeta A
Abad-Motos A
Abate E
Abatini C
Abbadessa F
Abbas AM
Abbassi-Ghadi N
Abbott D
Abbott T
Abbott Tom EF
Abd Elazeem HAS
Abdalla M
Abdallah M
Abdel Al S
Abdel Jalil R
Abdeldayem H
Abdelkader Salama I
Abdelkarem MM
Abdelkarim M
Abdelmajeed A
Abdelrahman A
Abdelrahman S
Abdelsamed A
Abdou M
Abdulkareem A
Abdulwahed E
Abdur-Rahman L
Abel MK
Abellán M
Aboelkassem Ibrahim A
Abosamak NE
Abou Chaar MK
Abou Chaar Mohammad K.
Abou-Khalil J
Abouassi A
Aboulkassem H
Abreu da Silva A
Abu Za’nouneh FJ
Abu J
Abu-Nayla I
Abubakar A
Abukhalaf Sadi
Acebes García F
Achalandabaso Boira M
Acher A
Acrich E
Adamina M
Adamina Michel
Adamoli L
Addae-Boateng E
Ademuyiwa Adesoji O
Aderombi A
Adeyeye A
Adiamah A
Adishesh M
Agapov M
Agarwal Arnav
Aggarwal A
Aghayeva A
Agilinko J
Agnes A
Agostini C
Agoston P
Agrawal A
Agresta F
Aguado H
Aguilar Gonzalez M
Aguzzoli L
Ahad S
Ahmadi N
Ahmeidat A
Ahn JH
Aiken T
Aimé A
Ajlan A
Akalin M
Akaydin E
Akeel N
Akgor U
Akhtar MA
Akhter Rahman MM
Akilli H
Akin E
Akkour K
Akkulak Murat
Akmenkalne L
Al Abdallah M
Al Awwad S
Al Habes H
Al Maadany FS
Al Raddadi R
AL Sayed M
Al-Habib A
Al-Habsi R
Al-Ishaq Z
Al-Khayal K
Al-Masri M
Al-Mohammad A
Al-mukhtar A
Al-Najjar H
Al-omishy H
Al-Sarireh B
Al-Tamimi Y
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Alakaloko Felix
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Alazawi D
Albertsmeier M
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Alcaide Matas F
Alconchel F
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Aldecoa Ansorregui I
Alderson Derek
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Alemanno G
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Alhalal H
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Lee M
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Omar Omar
on behalf of the COVIDSurg Collaborative
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Passot G
Pata Francesco
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Yıldırım A
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Öğücü H
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Ćoza I
Šimko K
Šćepanović V
Žatecký J
Камалов А
Publication venue: American Society of Clinical Oncology
Publication date: 01/01/2021
Field of study

Keele Research Repository

Outcomes after perioperative SARS-CoV-2 infection in patients with proximal femoral fractures: an international cohort study

Author: A'Court J
Aawsaj Y
Abbadessa F
Abbas A
Abbott S
Abdalaziz H
Abdalla M
Abdeh L
Abdelsaid K
Abdou H
Abdul-Jabar H
Abood A
Abou-Foul AK
Abrate A
Abu-Nayla I
Abual-Rub Z
Abuown A
Adamec A
Adegbola S
Ademuyiwa AO
Advani R
Aftab R
Agarwal A
Agarwal K
Aggarwal A
Aghababyan K
Agilinko J
Agrawal S
Ahad S
Ahmad Y
Ahmed Elamin H
Ahmed I
Ahmeidat A
Akhtar MA
Al Ameer E
Al-mukhtar A
Al-omishy H
Al-Samaraee A
Al-Sukaini A
Al-Yaseen M
Aladeojebi A
Alanbuki A
Alderson D
Aldridge K
Alexander ME
Alga A
Ali M
Ali Mahmoud F
Ali S
Allana A
Allen M
Almeida AC
Almond M
Alotaibi M
Alqallaf A
Alsakkaf M
Alser O
Alser O
Altomare DF
Alves R
Alwadiya A
Alzetani A
Amaral MJ
Ambler GK
Ameerally P
Anania G
Anazor F
Anderson C
Andrade R
Andreani SM
Andronic A
Aneke IA
Angamuthu N
Anjarwalla N
Antar M
Anthoney J
Anton-Eguia BT
Antunes J
Apampa AA
Aragon Achig EJ
Archer JE
Arigoni M
Arkani S
Armao T
Arminio A
Arnaud AP
Arrieta M
Asaad P
Ascensao J
Ashcroft J
Asher S
Askari A
Athayde Nemesio R
Augestad KM
Aujayeb A
Aujayeb A
Awadallah M
Ayeni F
Ayorinde J
Azevedo P
Baban C
Babawale O
Babu BHB
Bacarese-Hamilton J
Bacarese-Hamilton T
Badran A
Bagouri E
Baig M
Baig MMAS
Baker M
Baker OJ
Balaguer-Castro M
Balakrishnan A
Balasubramaniam D
Balasubramanian SP
Balau P
Baldwin AJ
Ballabio M
Ballantyne K
Baltazar G
Bandyopadhyay S
Bankhad-Kendall B
Bankhead-Kendall B
Bankhead-Kendall B
Baquedano M
Barbe Y
Barbier L
Barmayehvar B
Barmpagianni C
Barret E
Barry C
Bartsch A
Basgaran A
Basha A
Bashkirova V
Baskaran D
Bateman A
Bath MF
Baumber R
Baxter Z
Bayer J
Beak P
Beamish AJ
Begona E
Bekheit M
Belcher E
Bellis C
Beltran-Miranda P
Ben-Sassi A
Bence M
Benitez-Linero I
Benjamin MW
Benson RA
Bernal-Sprekelsen JC
Bernasconi M
Bevan K
Bhalla A
Bhangu A
Bhangu A
Bhangu A
Bhasin S
Bhaskar Pala RR
Bhatia K
Bhattacharya S
Bhojwani D
Bhutiani N
Bierman W
Bisagni P
Blair J
Blake I
Blanco J
Blanco-Colino R
Blas Laina JL
Blasco-Moreu J
Blasco-Torres L
Bleibleh S
Blencowe NS
Bloom O
Blundell C
Boal M
Board T
Bobak P
Bodla AS
Boeckxstaens A
Boeker C
Bond-Smith G
Booth K
Bordenave M
Borghi F
Borgstein ABJ
Bosanquet D
Bosch KD
Bouche PA
Bourke G
Bowen D
Branco C
Brar A
Brathwaite CEM
Bravo A Minaya
Breda D
Breen K
Breen KA
Breik O
Brennan C
Brennan P
Bretherton C
Bretherton C
Brian E
Britton E
Brown A
Brown BC
Brown O
Brown O
Brown S
Brown SR
Brown V
Brunelli A
Brunt A
Buarque I Lima
Burahee A
Burke JR
Byrne J
Byrne MHV
Cabeleira A
Cadersa A
Cagigal Ortega EP
Caja Vivancos P
Callahan MP
Callan R
Calvo Rey A
Camacho C
Camacho-Carrasco P
Campain N
Campbell R
Campuzano-Bitterling B
Canhoto C
Cao H
Capitan-Morales L
Capitelli-McMahon H
Caputo M
Carcoforo P
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Fernandez-Marin MR
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Finch JG
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Gracia I
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Grainger T
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Green S
Greenhalgh MS
Griffin XL
Griffiths E
Griffiths E
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Grimaldi Di Maria S
Grimley E
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Guariglia CA
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Hadfield JN
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Henegouwen van Berge MI
Hennessy EA
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Henshall DE
Heritage E
Hernandez E
Hernandez I
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Izquierdo O
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Winter SC
Winyard J
Witek A
Wong K
Wood ML
Woods R
Woodward Z
Wright FL
Wright N
Xicola Martinez M
Xyda S
Yalamanchili S
Yanez C
Yang H
Yassin N
Yener A
Yershov D
Young A
Young R
Yousef Y
Youssef M
Zadegan F
Zafar N
Zahid H
Zakai D
Zamvar V
Zeiton M
Zerbib P
Zhang Y
Zier L
Zowgar A
Publication venue: 'BMJ'
Publication date: 01/01/2021
Field of study

Objectives Studies have demonstrated high rates of mortality in people with proximal femoral fracture and SARS-CoV-2, but there is limited published data on the factors that influence mortality for clinicians to make informed treatment decisions. This study aims to report the 30-day mortality associated with perioperative infection of patients undergoing surgery for proximal femoral fractures and to examine the factors that influence mortality in a multivariate analysis. Setting Prospective, international, multicentre, observational cohort study. Participants Patients undergoing any operation for a proximal femoral fracture from 1 February to 30 April 2020 and with perioperative SARS-CoV-2 infection (either 7 days prior or 30-day postoperative). Primary outcome 30-day mortality. Multivariate modelling was performed to identify factors associated with 30-day mortality. Results This study reports included 1063 patients from 174 hospitals in 19 countries. Overall 30-day mortality was 29.4% (313/1063). In an adjusted model, 30-day mortality was associated with male gender (OR 2.29, 95% CI 1.68 to 3.13, p80 years (OR 1.60, 95% CI 1.1 to 2.31, p=0.013), preoperative diagnosis of dementia (OR 1.57, 95% CI 1.15 to 2.16, p=0.005), kidney disease (OR 1.73, 95% CI 1.18 to 2.55, p=0.005) and congestive heart failure (OR 1.62, 95% CI 1.06 to 2.48, p=0.025). Mortality at 30 days was lower in patients with a preoperative diagnosis of SARS-CoV-2 (OR 0.6, 95% CI 0.6 (0.42 to 0.85), p=0.004). There was no difference in mortality in patients with an increase to delay in surgery (p=0.220) or type of anaesthetic given (p=0.787). Conclusions Patients undergoing surgery for a proximal femoral fracture with a perioperative infection of SARS-CoV-2 have a high rate of mortality. This study would support the need for providing these patients with individualised medical and anaesthetic care, including medical optimisation before theatre. Careful preoperative counselling is needed for those with a proximal femoral fracture and SARS-CoV-2, especially those in the highest risk groups. Trial registration number NCT0432364

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