Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

Modeling of the reticulation kinetics of alginate/pluronic blends for biomedical applications

In this work, blends of alginate/pluronic (F127) for biomedical applications were investigated. In particular, the kinetics of alginate chain reticulation by bivalent cationswas studied by experimental and modeling approaches. Two kinds of sodium alginate were tested to obtain hard gel films. The thicknesses of the reticulated alginate films were measured as function of the exposure time and of the reticulating copper (Cu2+) solution concentration. The kinetics was described by a proper model able to reproduce the experimental data. The model parameters, evaluated based on the measurements of thicknesses as function of Cu2+ concentration and exposure time, were further validated by comparing the prediction of the modelwith another set of independent measurement; here, the depletion of Cu2+ ions in the conditioning solution above the reacting gel is measured as function of time. The tuned model could be used in the description of the future applications of the blend

Effect of the mGluR5-NAM Basimglurant on Behavior in Adolescents and Adults with Fragile X Syndrome in a Randomized, Double-Blind, Placebo-Controlled Trial: FragXis Phase 2 Results.

Preclinical data suggest that inhibition of the metabotropic glutamate receptor 5 (mGluR5) receptor might hold therapeutic benefits in Fragile X syndrome (FXS). Treatment of Fmr1 knockout mice with mGluR5-negative allosteric modulators (NAMs) has been reported to correct a broad range of phenotypes related to FXS. The early short-term clinical trials with mGluR5 NAMs, including basimglurant, assessing the effects in individuals with FXS, were supportive of further exploration in larger, well-controlled trials. We evaluated basimglurant, a potent and selective mGluR5 NAM, in a 12-week, double-blind, parallel-group study of 183 adults and adolescents (aged 14-50, mean 23.4 years) with FXS. Individuals with an FMR1 full mutation were randomized to placebo or one of two doses of basimglurant. The primary efficacy endpoint was the change from baseline in behavioral symptoms using the Anxiety Depression and Mood Scale (ADAMS) total score. All treatment arms showed marked behavioral improvements from baseline to week 12 with less improvement in the basimglurant 1.5 mg arm than placebo; however, basimglurant 0.5 mg was inferior to placebo in the ADAMs total score. Treatment with basimglurant was overall well-tolerated. A higher incidence of adverse events classified as psychiatric disorders were reported in patients treated with basimglurant, including three patients with hallucinations or psychosis. In this phase 2 clinical trial, basimglurant did not demonstrate improvement over placebo. Evaluation of the overall risk-benefit in younger patient populations is an important consideration for the design of potential further investigations of efficacy with this class of medications

Age and Multimorbidity Predict Death Among COVID-19 Patients: Results of the SARS-RAS Study of the Italian Society of Hypertension

Several factors have been proposed to explain the high death rate of the coronavirus disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related treatment with Renin Angiotensin System inhibitors. Also, age and multimorbidity might be confounders. No sufficient data are available to demonstrate their independent role. We designed a cross-sectional, observational, multicenter, nationwide survey in Italy to verify whether renin-angiotensin system inhibitors are related to COVID-19 severe outcomes. We analyzed information from Italian patients diagnosed with COVID-19, admitted in 26 hospitals. One thousand five hundred ninety-one charts (male, 64.1%; 66±0.4 years) were recorded. At least 1 preexisting condition was observed in 73.4% of patients, with hypertension being the most represented (54.9%). One hundred eighty-eight deaths were recorded (11.8%; mean age, 79.6±0.9 years). In nonsurvivors, older age, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease, coronary artery diseases, and heart failure were more represented than in survivors. The Charlson Comorbidity Index was significantly higher in nonsurvivors compared with survivors (4.3±0.15 versus 2.6±0.05; P<0.001). ACE (angiotensin-converting enzyme) inhibitors, diuretics, and β-blockers were more frequently used in nonsurvivors than in survivors. After correction by multivariate analysis, only age (P=0.0001), diabetes mellitus (P=0.004), chronic obstructive pulmonary disease (P=0.011), and chronic kidney disease (P=0.004) but not hypertension predicted mortality. Charlson Comorbidity Index, which cumulates age and comorbidities, predicts mortality with an exponential increase in the odds ratio by each point of score. In the COVID-19 outbreak, mortality is predicted by age and the presence of comorbidities. Our data do not support a significant interference of hypertension and antihypertensive therapy on COVID-19 lethality. Registration- URL: https://www.clinicaltrials.gov; Unique identifier: NCT04331574

Prevalence and determinants of resistant hypertension in a sample of patients followed in Italian hypertension centers: results from the MINISAL-SIIA study program

The aim of this study was to detect the prevalence of resistant hypertension (RH), allowing for adherence to appropriate lifestyle measures according to European Society of Hypertension-European Society of Cardiology (ESH-ESC) 2013 guidelines, in a sample of 1284 hypertensive subjects participating at the MINISAL-SIIA study. Hypertensive patients were recruited in 47 Italian centres, recognised by the Italian Society of Hypertension. Anthropometric indexes, blood pressure and 24-h urinary sodium (Na24h) and potassium (K24h) excretion were measured. Data on antihypertensive therapy were available for 1177 (92%) subjects. The population was divided into three groups (North, Central and South), according to their geographical location. Accounting only at the treatment criteria, the prevalence of RH was 8.2% (96/1177). RH prevalence in the southern, central and northern regions was respectively: 1, 3.8 and 3.3% (P<0.001). Participants with RH were older and showed a higher body mass index (BMI) and waist circumference compared with other subjects (P<0.005). RH risk was statistically significant (P<0.01) increased of 1.52-fold (95% confidence interval (CI):1.20-1.92) for one unit increase in s.d. score of age (11 years), and 1.50-fold (95% CI:1.22-1.83) for one unit increase in s.d. score of BMI (4.5 kg m-2). Including in RH diagnosis also the adherence to appropriate lifestyle measures, such as dietary salt restriction (Na24h <100 mmol) and normal BMI (18-25 kg m-2), RH prevalence felt respectively to 2.2% (26/1177) and 0.8% (9/1177). In conclusion in this national sample of Italian hypertensive population, among participants following both drug treatment and lifestyle modifications advises, the 'true' RH prevalence appears to be particularly lo

Validation of an easy questionnaire on the assessment of salt habit: the MINISAL-SIIA Study Program

BACKGROUND/OBJECTIVES: The aim of the present study was to validate a short questionnaire on habitual dietary salt intake, to quickly and easily identify individuals whose salt consumption exceeds recommended levels. SUBJECTS/METHODS: A total of 1131 hypertensive subjects participating in the MINISAL-SIIA study were included in the analysis. Anthropometric indexes, blood pressure, and 24-h urinary sodium excretion (NaU) were measured. A fixed-sequence questionnaire on dietary salt intake was administered. RESULTS: NaU was significantly associated with scores, with a linear association across categories (p for trend \u200985\u2009mmol/day) and "very high NaU" (NaU\u2009>\u2009170\u2009mmol/day) was 86 and 35%, respectively. The score of the questionnaire had a significant ability to detect both "high NaU"-with a specificity of 95% at the score of 10 points-and "very high NaU"-with a specificity of 99.6% at score of 13 points. CONCLUSIONS: The main results of the study indicates that a higher score of this short questionnaire is distinctive of habitual high salt consumption in hypertensive patients

Validation of an easy questionnaire on the assessment of salt habit: the MINISAL-SIIA Study Program

Background/objectives: The aim of the present study was to validate a short questionnaire on habitual dietary salt intake, to quickly and easily identify individuals whose salt consumption exceeds recommended levels. Subjects/methods: A total of 1131 hypertensive subjects participating in the MINISAL-SIIA study were included in the analysis. Anthropometric indexes, blood pressure, and 24-h urinary sodium excretion (NaU) were measured. A fixed-sequence questionnaire on dietary salt intake was administered. Results: NaU was significantly associated with scores, with a linear association across categories (p for trend &lt;0.0001). In addition, participants who achieved a total score above the median value (eight points) had significantly higher NaU than those whose score was below median (p &lt; 0.0001). In the total sample, the prevalence of “high NaU” (NaU &gt; 85 mmol/day) and “very high NaU” (NaU &gt; 170 mmol/day) was 86 and 35%, respectively. The score of the questionnaire had a significant ability to detect both “high NaU”—with a specificity of 95% at the score of 10 points—and “very high NaU”—with a specificity of 99.6% at score of 13 points. Conclusions: The main results of the study indicates that a higher score of this short questionnaire is distinctive of habitual high salt consumption in hypertensive patients

Validation of an easy questionnaire on the assessment of salt habit: the MINISAL-SIIA Study Program

Background/objectives: The aim of the present study was to validate a short questionnaire on habitual dietary salt intake, to quickly and easily identify individuals whose salt consumption exceeds recommended levels. Subjects/methods: A total of 1131 hypertensive subjects participating in the MINISAL-SIIA study were included in the analysis. Anthropometric indexes, blood pressure, and 24-h urinary sodium excretion (NaU) were measured. A fixed-sequence questionnaire on dietary salt intake was administered. Results: NaU was significantly associated with scores, with a linear association across categories (p for trend &lt;0.0001). In addition, participants who achieved a total score above the median value (eight points) had significantly higher NaU than those whose score was below median (p &lt; 0.0001). In the total sample, the prevalence of \u201chigh NaU\u201d (NaU &gt; 85 mmol/day) and \u201cvery high NaU\u201d (NaU &gt; 170 mmol/day) was 86 and 35%, respectively. The score of the questionnaire had a significant ability to detect both \u201chigh NaU\u201d\u2014with a specificity of 95% at the score of 10 points\u2014and \u201cvery high NaU\u201d\u2014with a specificity of 99.6% at score of 13 points. Conclusions: The main results of the study indicates that a higher score of this short questionnaire is distinctive of habitual high salt consumption in hypertensive patients

Excess dietary sodium and inadequate potassium intake by hypertensive patients in Italy

NTRODUCTION: The aim of the study was to assess the age-specific, sex-specific, and region-specific average sodium and potassium intake and its association with anthropometric characteristics in a sample of the Italian adult hypertensive population. METHODS: A total of 1232 hypertensive patients were recruited consecutively by 47 centers recognized by the Italian Society of Hypertension. The enrolled participants were on stable antihypertensive treatment. Anthropometric indices, blood pressure, 24-h urinary sodium, and potassium excretion were measured and used as proxy for the average daily sodium and potassium intake. RESULTS: The average sodium intake was 172mmol (or 10.1g of salt/day) among men and 138 (or 8.1) among women, with no difference among geographical areas. Over 90% of men and 81% of women had a consumption higher than the recommended standard dietary intake of 5g/day. The average potassium intake was 63 and 56mmol, respectively in men and women, again without geographical differences, nearly 92% of men and 95% of women having an intake lower than the recommended intake (100mmol/day or 3.9g/day). There was a significant trend to a gradual decrease in sodium intake with age in both sexes (P<0.001). There was also a direct association between BMI and sodium intake in both sexes, this association being independent of age (P<0.001). CONCLUSION: In this national sample of the Italian hypertensive population, dietary sodium intake was largely higher and potassium intake much lower than the recommended intakes, and this was true for all geographical areas. Overweight and obese hypertensive patients had particularly high sodium intakes

La fuerza de la virtualidad. Experiencias sobre docencia, investigación y gestión en tiempos excepcionales

La fuerza de la virtualidad reúne un conjunto de relatos sobre trabajos de docencia, investigación, extensión y gestión, realizados en la Facultad de Ciencias Económicas de la Universidad Nacional de Córdoba durante el año 2020, en el marco de las medidas de distanciamiento social, preventivo y obligatorio. Esta situación de excepción puso a prueba los modos habituales de pensar y gestionar la institución en su totalidad, debiendo mudar a la fuerza a la virtualidad e idear acciones conducentes a resolver problemáticas concretas.Fil: Álvarez, Alicia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Andonian, Olga G. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Arcos, Ricardo Fabián. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Argento, Rosa. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Arónica, Sandra. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Asís, Susana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Azcona, Noelia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Balian, Andrea Laura. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Baraldi, Gladis Ruth. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Bazán, Eugenia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Belén, Julián. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Beltrán, Natacha. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Berrino, Liliana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Blatto, Lautaro. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Bravino, Laura Susana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Bruno, Juan Manuel. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cacciagiú, Víctor. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cáceres, Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cagliero, Maria Florencia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cargnelutti, Jennifer. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Caro, Norma Patricia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Carrizo, Elvira. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Casanova, Gustavo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Casas, Lucía. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Casini, Rosanna. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Ceballos Salas, María Valentina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Chaves, Agustín. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cima, Josefina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Colella, Belén. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cornejo, Roberto Antonio. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Cuttica, Mariela. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: D´Allera, Natalia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Darbyshire, María Eugenia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: De La Rosa, Adolfo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Demo, Horacio. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Descalzi, Ricardo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Díaz, Cecilia Del Valle. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Díaz, Myriam. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Etchegorry, Cristina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Fernández, Ana Valentina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Fernández, María Eugenia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Ferrero, Lía Ivana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: García, Fernando. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: García, Siria Miriam. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Giménez, Miriam Mónica. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Giovanardi, Mariana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: González, Mariana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Guajardo Molina, Vanesa. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Guardiola, Mariana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Guevel, Hernán Pablo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Huanchicay, Silvia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Iturralde, Ivan. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Jaluf, Marcelo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Jornet, Paola Andrea. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Juárez, Alejandra. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Juri, Pablo R. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Kaufman, Judith. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Larrosa, Griselda. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; ArgentinaFil: Lencisa, Silvina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Lingua, Matías. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Lladós, Gabriela. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Llaryora, María Paz. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: López Coppari, Joaquín. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: López, Eliana Marisel. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: López, Sonia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Margaría, Oscar. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Martínez, Jacqueline. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Martínez, Milagro. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Martínez, Pilar. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Mina, Jorge. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Mizraji, Mariana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Molina, Florencia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Moneta Pizarro, Adrián Maximiliano. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Moyano, Carina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Nahas, Estefanía. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Oliva Eugenia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Ortíz, Pablo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Peretto, Claudia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Pereyra, Liliana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Pérez Bellettini, María Mercedes. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Pérez, Diana A. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Pérez, Guillermo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Perlati, Sebastián. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Perrulli, Cintia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Picazzo, Hugo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Pozetti, Maximiliano. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Quintá, Karina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Quiñones, Paula Soledad. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Quiroga Martínez, Facundo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rabbia Evelín Mariel. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Racagni, Josefina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rezzonico, Diego. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Ricci, María Beatriz. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Ristorto, Alejandra. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rivadera, Gastón. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rodríguez Saa, Pablo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Rosset, Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Sabulsky, Gabriela. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Saffe, Juan. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Saino, Martín. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Salazar Solana, Alejandra. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Salerno, María Liliana. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Salvatierra, Luca. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Sánchez, Claudia Andrea. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Santillán, Gustavo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Sartori, Juan José Pompillo. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Saunders, Shirley. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Schultz, Alberto. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Senestrari, Selene Giselle. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Singh, Luis. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Slavin, Mariel V. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Smit, Evangelina. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Soria, Mónica. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Staricco, Juan. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Stimolo, María Inés. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Stumpf, Javier. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Tolosa, Leticia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Vázquez, Flavia. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Vera, Ailén. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Werbin, Eliana Mariela. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Yrusta, Lucas. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina.Fil: Zamboni, Pedro. Universidad Nacional de Córdoba. Facultad de Ciencias Económicas; Argentina