42 research outputs found
The TESS Triple-9 Catalog II: a new set of 999 uniformly-vetted exoplanet candidates
The Transiting Exoplanet Survey Satellite (TESS) mission is providing the
scientific community with millions of light curves of stars spread across the
whole sky. Since 2018 the telescope has detected thousands of planet candidates
that need to be meticulously scrutinized before being considered amenable
targets for follow-up programs. We present the second catalog of the Plant
Patrol citizen science project containing 999 uniformly-vetted exoplanet
candidates within the TESS ExoFOP archive. The catalog was produced by fully
exploiting the power of the Citizen Science Planet Patrol project. We vetted
TESS Objects of Interest (TOIs) based on the results of Discovery And Vetting
of Exoplanets DAVE pipeline. We also implemented the Automatic Disposition
Generator, a custom procedure aimed at generating the final classification for
each TOI that was vetted by at least three vetters. The majority of the
candidates in our catalog, TOIs, passed the vetting process and were
labelled as planet candidates. We ruled out candidates as false positives
and flagged as potential false positives. Our final dispositions and
comments for all the planet candidates are provided as a publicly available
supplementary table.Comment: 17 pages, 11 figures, 5 tables. Accepted for publication on MNRA
A systematic validation of hot Neptunes in TESS data
We statistically validated a sample of hot Neptune candidates applying a
two-step vetting technique using DAVE and TRICERATOPS. We performed a
systematic validation of 250 transit-like events in the Transiting Exoplanet
Survey Satellite (TESS) archive in the parameter region defined by d
and . Through our analysis, we identified 18 hot
Neptune-sized candidates, with a false positive probability . Nine of
these planet candidates still need to be confirmed. For each of the nine
targets we retrieved the stellar parameters using ARIADNE and derived
constraints on the planetary parameters by fitting the lightcurves with the
juliet package. Within this sample of nine candidates, we statistically
validated (i.e, with false positive probability < ) two systems (TOI-277
b and TOI-1288 b) by re-processing the candidates with TRICERATOPS along with
follow-up observations. These new validated exoplanets expand the known hot
Neptunes population and are high-priority targets for future radial velocities
follow-up.Comment: 24 pages, 20 figures. Accepted for publication on MNRA
TESS discovery of a super-Earth and two sub-Neptunes orbiting the bright, nearby, Sun-like star HD 22946
We report the Transiting Exoplanet Survey Satellite (TESS) discovery of a
three-planet system around the bright Sun-like star HD~22946(V=8.3 mag),also
known as TIC~100990000, located 63 parsecs away.The system was observed by TESS
in Sectors 3, 4, 30 and 31 and two planet candidates, labelled TESS Objects of
Interest (TOIs) 411.01 (planet ) and 411.02 (planet ), were identified on
orbits of 9.57 and 4.04 days, respectively. In this work, we validate the two
planets and recover an additional single transit-like signal in the light
curve, which suggests the presence of a third transiting planet with a longer
period of about 46 days.We assess the veracity of the TESS transit signals and
use follow-up imaging and time series photometry to rule out false positive
scenarios, including unresolved binary systems, nearby eclipsing binaries or
background/foreground stars contaminating the light curves. Parallax
measurements from Gaia EDR3, together with broad-band photometry and
spectroscopic follow-up by TFOP allowed us to constrain the stellar parameters
of TOI-411, including its radius of. Adopting this value,
we determined the radii for the three exoplanet candidates and found that
planet is a super-Earth, with a radius of , while
planet and are sub-Neptunian planets, with radii
of and respectively. By using
dynamical simulations, we assessed the stability of the system and evaluated
the possibility of the presence of other undetected, non-transiting planets by
investigating its dynamical packing. We find that the system is dynamically
stable and potentially unpacked, with enough space to host at least one more
planet between and .(Abridged)Comment: 21 pages, 12 figures. Accepted for publication on A&
SARS-CoV-2 vaccination modelling for safe surgery to save lives : data from an international prospective cohort study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty. Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year. Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population.Peer reviewe
The L 98-59 System: Three Transiting, Terrestrial-size Planets Orbiting a Nearby M Dwarf
We report the Transiting Exoplanet Survey Satellite (TESS) discovery of three terrestrial-size planets transiting L 98-59 (TOI-175, TIC 307210830)—a bright M dwarf at a distance of 10.6 pc. Using the Gaia-measured distance and broadband photometry, we find that the host star is an M3 dwarf. Combined with the TESS transits from three sectors, the corresponding stellar parameters yield planet radii ranging from 0.8 R ⊕ to 1.6 R ⊕. All three planets have short orbital periods, ranging from 2.25 to 7.45 days with the outer pair just wide of a 2:1 period resonance. Diagnostic tests produced by the TESS Data Validation Report and the vetting package DAVE rule out common false-positive sources. These analyses, along with dedicated follow-up and the multiplicity of the system, lend confidence that the observed signals are caused by planets transiting L 98-59 and are not associated with other sources in the field. The L 98-59 system is interesting for a number of reasons: the host star is bright (V = 11.7 mag, K = 7.1 mag) and the planets are prime targets for further follow-up observations including precision radial-velocity mass measurements and future transit spectroscopy with the James Webb Space Telescope; the near-resonant configuration makes the system a laboratory to study planetary system dynamical evolution; and three planets of relatively similar size in the same system present an opportunity to study terrestrial planets where other variables (age, metallicity, etc.) can be held constant. L 98-59 will be observed in four more TESS sectors, which will provide a wealth of information on the three currently known planets and have the potential to reveal additional planets in the system
Tildrakizumab for the Treatment of Moderate-to-Severe Psoriasis: Results from 52 Weeks Real-Life Retrospective Study
Background: Tildrakizumab, an anti-IL-23, showed promising efficacy and safety profiles in two randomized clinical-trials (reSURFACE-1 and reSURFACE-2), comparing tildrakizumab superiority to placebo and etanercept. Due to its recent availability in clinical-practice, real-life data are still limited. Objective: To assess the efficacy and safety of tildrakizumab in a real-world-practice in patients suffering from moderate-to-severe psoriasis. Methods: A 52-week observational retrospective study enrolled patients suffering from moderate-to-severe plaque-psoriasis, starting tildrakizumab treatment. Results: A total of 42 patients were included in the study. Mean PASI showed a significant reduction at each follow-up (p<0.001), reducing from 13.5±5.9 at baseline, 2.8±3.8 at week-28, resulting stable up to week-52. High rates of patients reached both PASI90 and PASI100 responses at both week 16 (PASI90: 52.4%, PASI100: 33.3%) and week 28 (PASI90: 76.1%, PASI100: 61.9%), maintaining these up to week 52 (PASI90: 73.8%, PASI100: 59.5%). The impact of treatment on patient's quality of life has been evaluated with DLQI, which showed a significant reduction during follow-ups. Conclusion: Our data confirm tildrakizumab as an effective and generally safe treatment for the management of moderate-to-severe psoriasis, with high rates of both PASI90 and PASI100 responses, and very few reported adverse events, up to 52 weeks of follow-up