Analysis on status of milk beverage consumption among the population in nine provinces of China

Objective This study aimed to describe the status of milk beverage consumption and the influence factors. Methods This study selected 13 953 samples by stratified multistage cluster random sampling in 2013. The study samples consisted of aged 3 and above with completed three non-consecutive 24 h dietary recalls and food frequency data. A Logistic regression was used to analyze the influence factors. Results The prevalence of milk beverage was 9.7% (1 350/13 953). The drinking frequency was 1.6% (217/13 953), 0.7% (94/13 953) and 7.4% (1 039/13 953) for whom consumed 1 or more times per day, 4 to 6 times per week, and 1 to 3 times per week, respectively. The prevalence was 8.5% (592/6 934) and 10.8% (758/7 019) for male and female, respectively. Stratified by age groups, the prevalence was the highest among 3 to 6-year-olds (35.5%, 165/465) and the lowest among 60 years and above (4.5%, 123/2 740). Urban prevalence (7.7%, 534/6 954) was lower than rural (11.7%, 816/6 999). The per capita consumption of milk beverage was 6.2 mL/d among all the participants (134.4 mL/d among consumers), and was 5.6 mL/d and 6.9 mL/d for male and female, respectively. Stratified by age groups, the consumption was the highest among 3 to 6-year-olds (35.6 mL/d) and the lowest among 60 years and above (2.6 mL/d). The consumption was lower in urban residents (3.2 mL/d) than that of rural residents (9.2 mL/d). Factors associated with the consumption of milk beverage were gender, age, occupation, urban-rural difference and region. Conclusion The prevalence and per capita consumption of milk beverage were relatively low among 3 years or above residents in China. Children and adolescents (3 to 17-year-old) are the main consumers of milk beverage

Analysis on sugar intake from carbonated beverages aged 3 years and above of China

Objective To investigate sugar intake from carbonated beverages of Chinese residents. Methods Multistage stratified random cluster and probability proportionate sampling method was used, and 27 485 residents aged 3 and above were included from one urban and one rural district of 14 provinces (cities) in China. Data was collected by non-continuous 3-day and 24-hour-dietary retrospective method. The added sugar content in 132 carbonated beverages was obtained through the investigation of added sugar content in beverages, the energy provided by added sugar in carbonated beverages was calculated and compared with the total dietary energy from the nutrition and health monitoring diet of Chinese residents, and energy supply ratio of added sugar in carbonated drinks was calculated. Results In 2014, the daily intake of added sugar from carbonated beverages was 0.5 g, and the energy supply ratio was 0.11%. The mean daily intake of added sugar was 13.4 g, the median was 12.3 g, and the energy supply ratio was 2.69%. The median daily intake of carbonated beverages for males (15.3 g) was higher than that for females (10.1 g), it was higher for the urban areas (13.8 g) than that for rural areas (10.7 g), the differences were statistically significant (P0.05). In addition, the consumption of carbonated beverages in urban areas (3.02%) was higher than that in rural areas (2.01%), the difference was statistically significant (P<0.05). The energy supply ratio of carbonated beverage in 13-17 age group was 3.41%. Conclusion Adolescents are the high consumption group of carbonated drinks, so we should strengthen health education to guide reasonable consumption

Microbiome-derived bile acids contribute to elevated antigenic response and bone erosion in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic, disabling and incurable autoimmune disease. It has been widely recognized that gut microbial dysbiosis is an important contributor to the pathogenesis of RA, although distinct alterations in microbiota have been associated with this disease. Yet, the metabolites that mediate the impacts of the gut microbiome on RA are less well understood. Here, with microbial profiling and non-targeted metabolomics, we revealed profound yet diverse perturbation of the gut microbiome and metabolome in RA patients in a discovery set. In the Bacteroides-dominated RA patients, differentiation of gut microbiome resulted in distinct bile acid profiles compared to healthy subjects. Predominated Bacteroides species expressing BSH and 7a-HSDH increased, leading to elevated secondary bile acid production in this subgroup of RA patients. Reduced serum fibroblast growth factor-19 and dysregulated bile acids were evidence of impaired farnesoid X receptor-mediated signaling in the patients. This gut microbiota-bile acid axis was correlated to ACPA. The patients from the validation sets demonstrated that ACPA-positive patients have more abundant bacteria expressing BSH and 7a-HSDH but less Clostridium scindens expressing 7a-dehydroxylation enzymes, together with dysregulated microbial bile acid metabolism and more severe bone erosion than ACPA-negative ones. Mediation analyses revealed putative causal relationships between the gut microbiome, bile acids, and ACPA-positive RA, supporting a potential causal effect of Bacteroides species in increasing levels of ACPA and bone erosion mediated via disturbing bile acid metabolism. These results provide insights into the role of gut dysbiosis in RA in a manifestation-specific manner, as well as the functions of bile acids in this gut-joint axis, which may be a potential intervention target for precisely controlling RA conditions.Comment: 38 pages, 6 figure

Synthesis and catalysis of chemically reduced metal–metalloid amorphous alloys

This is the published version. Copyright 2012 Royal Society of ChemistryAmorphous alloys structurally deviate from crystalline materials in that they possess unique short-range ordered and long-range disordered atomic arrangement. They are important catalytic materials due to their unique chemical and structural properties including broadly adjustable composition, structural homogeneity, and high concentration of coordinatively unsaturated sites. As chemically reduced metal–metalloid amorphous alloys exhibit excellent catalytic performance in applications such as efficient chemical production, energy conversion, and environmental remediation, there is an intense surge in interest in using them as catalytic materials. This critical review summarizes the progress in the study of the metal–metalloid amorphous alloy catalysts, mainly in recent decades, with special focus on their synthetic strategies and catalytic applications in petrochemical, fine chemical, energy, and environmental relevant reactions. The review is intended to be a valuable resource to researchers interested in these exciting catalytic materials. We concluded the review with some perspectives on the challenges and opportunities about the future developments of metal–metalloid amorphous alloy catalysts

The Seventeenth Data Release of the Sloan Digital Sky Surveys: Complete Release of MaNGA, MaStar and APOGEE-2 Data

This paper documents the seventeenth data release (DR17) from the Sloan Digital Sky Surveys; the fifth and final release from the fourth phase (SDSS-IV). DR17 contains the complete release of the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey, which reached its goal of surveying over 10,000 nearby galaxies. The complete release of the MaNGA Stellar Library (MaStar) accompanies this data, providing observations of almost 30,000 stars through the MaNGA instrument during bright time. DR17 also contains the complete release of the Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) survey which publicly releases infra-red spectra of over 650,000 stars. The main sample from the Extended Baryon Oscillation Spectroscopic Survey (eBOSS), as well as the sub-survey Time Domain Spectroscopic Survey (TDSS) data were fully released in DR16. New single-fiber optical spectroscopy released in DR17 is from the SPectroscipic IDentification of ERosita Survey (SPIDERS) sub-survey and the eBOSS-RM program. Along with the primary data sets, DR17 includes 25 new or updated Value Added Catalogs (VACs). This paper concludes the release of SDSS-IV survey data. SDSS continues into its fifth phase with observations already underway for the Milky Way Mapper (MWM), Local Volume Mapper (LVM) and Black Hole Mapper (BHM) surveys

Robust estimation of bacterial cell count from optical density

Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals &lt;1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake