50 research outputs found
CsI(Tl) for WIMP dark matter searches
We report a study of CsI(Tl) scintillator to assess its applicability in
experiments to search for dark matter particles. Measurements of the mean
scintillation pulse shapes due to nuclear and electron recoils have been
performed. We find that, as with NaI(Tl), pulse shape analysis can be used to
discriminate between electron and nuclear recoils down to 4 keV. However, the
discrimination factor is typically (10-15)% better than in NaI(Tl) above 4 keV.
The quenching factor for caesium and iodine recoils was measured and found to
increase from 11% to ~17% with decreasing recoil energy from 60 to 12 keV.
Based on these results, the potential sensitivity of CsI(Tl) to dark matter
particles in the form of neutralinos was calculated. We find an improvement
over NaI(Tl) for the spin independent WIMP-nucleon interactions up to a factor
of 5 assuming comparable electron background levels in the two scintillators.Comment: 16 pages, 8 figures, to be published in Nucl. Instrum. and Meth. in
Phys. Res.
Simulations of neutron background in a time projection chamber relevant to dark matter searches
Presented here are results of simulations of neutron background performed for
a time projection chamber acting as a particle dark matter detector in an
underground laboratory. The investigated background includes neutrons from rock
and detector components, generated via spontaneous fission and (alpha, n)
reactions, as well as those due to cosmic-ray muons. Neutrons were propagated
to the sensitive volume of the detector and the nuclear recoil spectra were
calculated. Methods of neutron background suppression were also examined and
limitations to the sensitivity of a gaseous dark matter detector are discussed.
Results indicate that neutrons should not limit sensitivity to WIMP-nucleon
interactions down to a level of (1 - 3) x 10^{-8} pb in a 10 kg detector.Comment: 27 pages (total, including 3 tables and 11 figures). Accepted for
publication in Nuclear Instruments and Methods in Physics Research - Section
Measurements of Scintillation Efficiency and Pulse-Shape for Low Energy Recoils in Liquid Xenon
Results of observations of low energy nuclear and electron recoil events in
liquid xenon scintillator detectors are given. The relative scintillation
efficiency for nuclear recoils is 0.22 +/- 0.01 in the recoil energy range 40
keV - 70 keV. Under the assumption of a single dominant decay component to the
scintillation pulse-shape the log-normal mean parameter T0 of the maximum
likelihood estimator of the decay time constant for 6 keV < Eee < 30 keV
nuclear recoil events is equal to 21.0 ns +/- 0.5 ns. It is observed that for
electron recoils T0 rises slowly with energy, having a value ~ 30 ns at Eee ~
15 keV. Electron and nuclear recoil pulse-shapes are found to be well fitted by
single exponential functions although some evidence is found for a double
exponential form for the nuclear recoil pulse-shape.Comment: 11 pages, including 5 encapsulated postscript figure
Neutron background in large-scale xenon detectors for dark matter searches
Simulations of the neutron background for future large-scale particle dark
matter detectors are presented. Neutrons were generated in rock and detector
elements via spontaneous fission and (alpha,n) reactions, and by cosmic-ray
muons. The simulation techniques and results are discussed in the context of
the expected sensitivity of a generic liquid xenon dark matter detector.
Methods of neutron background suppression are investigated. A sensitivity of
pb to WIMP-nucleon interactions can be achieved by a
tonne-scale detector.Comment: 35 pages, 13 figures, 2 tables, accepted for publication in
Astroparticle Physic
First Results from the DRIFT-IIa Dark Matter Detector
Data from the DRIFT-IIa directional dark matter experiment are presented,
collected during a near continuous 6 month running period. A detailed
calibration analysis comparing data from gamma-ray, x-ray and neutron sources
to a GEANT4 Monte Carlo simulations reveals an efficiency for detection of
neutron induced recoils of 94+/-2(stat.)+/-5(sys.)%. Software-based cuts,
designed to remove non-nuclear recoil events, are shown to reject 60Co
gamma-rays with a rejection factor of better than 8x10-6 for all energies above
threshold. An unexpected event population has been discovered and is shown here
to be due to the alpha-decay of 222Rn daughter nuclei that have attached to the
central cathode. A limit on the flux of neutrons in the Boulby Underground
Laboratory is derived from analysis of unshielded and shielded data.Comment: 43 pages, 14 figures, submitted to Astroparticle Physic
Track Reconstruction and Performance of DRIFT Directional Dark Matter Detectors using Alpha Particles
First results are presented from an analysis of data from the DRIFT-IIa and
DRIFT-IIb directional dark matter detectors at Boulby Mine in which alpha
particle tracks were reconstructed and used to characterise detector
performance--an important step towards optimising directional technology. The
drift velocity in DRIFT-IIa was [59.3 +/- 0.2 (stat) +/- 7.5 (sys)] m/s based
on an analysis of naturally-occurring alpha-emitting background. The drift
velocity in DRIFT-IIb was [57 +/- 1 (stat) +/- 3 (sys)] m/s determined by the
analysis of alpha particle tracks from a Po-210 source. 3D range reconstruction
and energy spectra were used to identify alpha particles from the decay of
Rn-222, Po-218, Rn-220 and Po-216. This study found that (22 +/- 2)% of Po-218
progeny (from Rn-222 decay) are produced with no net charge in 40 Torr CS2. For
Po-216 progeny (from Rn-220 decay) the uncharged fraction is (100 +0 -35)%.Comment: 27 pages, 12 figures, 5 tables. Submitted to Nuclear Instruments and
Methods in Physics Research, Section A. Subj-class: Instrumentation and
Detector
Measurement of the Range Component Directional Signature in a DRIFT-II Detector using 252Cf Neutrons
The DRIFT collaboration utilizes low pressure gaseous detectors to search for
WIMP dark matter with directional signatures. A 252Cf neutron source was placed
on each of the principal axes of a DRIFT detector in order to test its ability
to measure directional signatures from the three components of very low energy
(~keV/amu) recoil ranges. A high trigger threshold and the event selection
procedure ensured that only sulfur recoils were analyzed. Sulfur recoils
produced in the CS2 target gas by the 252Cf source closely match those expected
from massive WIMP induced sulfur recoils. For each orientation of the source a
directional signal from the range components was observed, indicating that the
detector is directional along all 3 axes. An analysis of these results yields
an optimal orientation for DRIFT detectors when searching for a directional
signature from WIMPs. Additional energy dependent information is provided to
aid in understanding this effect.Comment: 14 pages, 1 Table, 8 Figure
The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control.
The stable fly, Stomoxys calcitrans, is a major blood-feeding pest of livestock that has near worldwide distribution, causing an annual cost of over $2 billion for control and product loss in the USA alone. Control of these flies has been limited to increased sanitary management practices and insecticide application for suppressing larval stages. Few genetic and molecular resources are available to help in developing novel methods for controlling stable flies.
This study examines stable fly biology by utilizing a combination of high-quality genome sequencing and RNA-Seq analyses targeting multiple developmental stages and tissues. In conjunction, 1600 genes were manually curated to characterize genetic features related to stable fly reproduction, vector host interactions, host-microbe dynamics, and putative targets for control. Most notable was characterization of genes associated with reproduction and identification of expanded gene families with functional associations to vision, chemosensation, immunity, and metabolic detoxification pathways.
The combined sequencing, assembly, and curation of the male stable fly genome followed by RNA-Seq and downstream analyses provide insights necessary to understand the biology of this important pest. These resources and new data will provide the groundwork for expanding the tools available to control stable fly infestations. The close relationship of Stomoxys to other blood-feeding (horn flies and Glossina) and non-blood-feeding flies (house flies, medflies, Drosophila) will facilitate understanding of the evolutionary processes associated with development of blood feeding among the Cyclorrhapha
Search for jet extinction in the inclusive jet-pT spectrum from proton-proton collisions at s=8 TeV
Published by the American Physical Society under the terms of the Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and the published articles title, journal citation, and DOI.The first search at the LHC for the extinction of QCD jet production is presented, using data collected with the CMS detector corresponding to an integrated luminosity of 10.7ââfbâ1 of proton-proton collisions at a center-of-mass energy of 8 TeV. The extinction model studied in this analysis is motivated by the search for signatures of strong gravity at the TeV scale (terascale gravity) and assumes the existence of string couplings in the strong-coupling limit. In this limit, the string model predicts the suppression of all high-transverse-momentum standard model processes, including jet production, beyond a certain energy scale. To test this prediction, the measured transverse-momentum spectrum is compared to the theoretical prediction of the standard model. No significant deficit of events is found at high transverse momentum. A 95% confidence level lower limit of 3.3 TeV is set on the extinction mass scale
Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's) : an ARChiVe Cohort Study
OBJECTIVE:
To uniquely classify children with microscopic polyangiitis (MPA), to describe their demographic characteristics, presenting clinical features, and initial treatments in comparison to patients with granulomatosis with polyangiitis (Wegener's) (GPA).
METHODS:
The European Medicines Agency (EMA) classification algorithm was applied by computation to categorical data from patients recruited to the ARChiVe (A Registry for Childhood Vasculitis: e-entry) cohort, with the data censored to November 2015. The EMA algorithm was used to uniquely distinguish children with MPA from children with GPA, whose diagnoses had been classified according to both adult- and pediatric-specific criteria. Descriptive statistics were used for comparisons.
RESULTS:
In total, 231 of 440 patients (64% female) fulfilled the classification criteria for either MPA (n\u2009=\u200948) or GPA (n\u2009=\u2009183). The median time to diagnosis was 1.6 months in the MPA group and 2.1 months in the GPA group (ranging to 39 and 73 months, respectively). Patients with MPA were significantly younger than those with GPA (median age 11 years versus 14 years). Constitutional features were equally common between the groups. In patients with MPA compared to those with GPA, pulmonary manifestations were less frequent (44% versus 74%) and less severe (primarily, hemorrhage, requirement for supplemental oxygen, and pulmonary failure). Renal pathologic features were frequently found in both groups (75% of patients with MPA versus 83% of patients with GPA) but tended toward greater severity in those with MPA (primarily, nephrotic-range proteinuria, requirement for dialysis, and end-stage renal disease). Airway/eye involvement was absent among patients with MPA, because these GPA-defining features preclude a diagnosis of MPA within the EMA algorithm. Similar proportions of patients with MPA and those with GPA received combination therapy with corticosteroids plus cyclophosphamide (69% and 78%, respectively) or both drugs in combination with plasmapheresis (19% and 22%, respectively). Other treatments administered, ranging in decreasing frequency from 13% to 3%, were rituximab, methotrexate, azathioprine, and mycophenolate mofetil.
CONCLUSION:
Younger age at disease onset and, perhaps, both gastrointestinal manifestations and more severe kidney disease seem to characterize the clinical profile in children with MPA compared to those with GPA. Delay in diagnosis suggests that recognition of these systemic vasculitides is suboptimal. Compared with adults, initial treatment regimens in children were comparable, but the complete reversal of female-to-male disease prevalence ratios is a provocative finding