Psychometric properties of Malay-translated version of “desire for drug questionnaire” among opioid dependents

Background: Drug craving is a subjective experience that can induce and reinforce individual to consume drugs. Desire for Drug Questionnaire (DDQ) is one of the screening tools used to measure drug craving severity in individuals with drug dependent. However, the original English version of DDQ has never been translated into Malay language nor validated in Malaysia. Thus, the objective of this study is to translate the DDQ questionnaire and to assess the psychometric properties of the translated Malay version of DDQ among opioid dependents. Methodology: DDQ was translated from English into Malay language by language experts using forward and backward translation methods. The questionnaire was then undergone assessment for its validity and reliability. Construct validity of the questionnaire was tested using exploratory principal components factor analysis while internal consistency of the questionnaire was tested using Cronbach’s alpha. Eigenvalue more than 1 was set to be the criteria for factor extraction. Result: A total of 55 Methadone Maintenance Treatment (MMT) male clients had participated in this study. For all the 14-items in the questionnaire, the factor loading values were from 0.434 to 0.958. The exploratory principal component factor analysis for DDQ delineates all 14-items into three factors with variance of 45.51%. The Cronbach’s alpha value was good with 0.86 for total score, 0.79 for factor 1, 0.81 for factor 2 and 0.75 for factor 3. Conclusion: Malay-translated version of DDQ questionnaires has good psychometric properties. The questionnaire could be considered as a reliable instrument for assessment of drug craving level in Malay-language speaking drug dependents

Dissolved gas analysis of transformers based on rough set and fuzzy logic methods

Dissolved Gas Analysis (DGA) is one of the common approaches that can be used to detect incipient faults in transformers. According to IEEE C57/104-2008 and IEC 60599 standards, there are many DGA techniques that can be used to interpret the type of faults. In this paper, an alternative method to diagnose faults in transformers based on Rough Set (RS) and Fuzzy Logic (FL) is proposed. The rules for the FL are generated from the attributes of RS. Based on this method, it was found that the efficiency of the fault interpretation based on RS/FL is improved compared to the conventional methods in standards

Modelling decision support system for selection maahad tafiz center using analytical hierarchal analysis

Today, the interest of the community to send their children to religious-based schools that is Maahad Tahfiz Center (MTC)) whether managed by Government (State or Federal), private individuals, nonprofit organization (NGO) or certain organizations is very high. The demand that exceeds this offer has seen the growth of MTC rapidly. This situation provides many choices and advantages to parents. However, there is anxiety among parents to choose the MTC that fulfills the features that they want.  Hence modeling decision support system (DSS) in a MTC selection has been modeled using Analytical Hierarchy Process (AHP) provides the effective way for parents to select appropriate MTC. AHP is an effective tool for dealing with the complex decision making and aid the parents to set priorities and provide the best decision in selection MTC. Hopefully by using this model and future development of this model will help the parents make the best choices of MTC based on their preferences.

Factors associated with parenting practices among preschoolers' parents in Ampang and Serdang, Selangor, 2016

Parenting practices is an important factor that determines child's behaviour. In the past 40 years, research proves that child’s development are affected by parenting. Hence, it is also important to know that there are factors that are associated with the parenting practice because that factors can determine whether the parenting being used is good or bad. To determine the factors (parents’ attitude, parental knowledge) associated with parenting practices among preschoolers' parents in Ampang and Serdang, Selangor. This was a cross-sectional study. Self-administered questionnaires were used to collect data from 252 preschoolers’ parents from 14 Tabika KEMAS in Ampang and Serdang, Selangor. The data collected were analysed by using SPSS version 21.0. Parental knowledge (source) and parents’ attitude (overprotective, interest in knowledge) were the most common factors affecting parenting practices of preschoolers' parents from 14 Tabika KEMAS in Ampang and Serdang, Selangor. Overall, parents play an important role in developing skills of good parenting practices to be applied on their children later on

Compatible solid polymer electrolyte based on methyl cellulose for energy storage application: structural, electrical, and electrochemical properties

Compatible green polymer electrolytes based on methyl cellulose (MC) were prepared for energy storage electrochemical double-layer capacitor (EDLC) application. X-ray diffraction (XRD) was conducted for structural investigation. The reduction in the intensity of crystalline peaks of MC upon the addition of sodium iodide (NaI) salt discloses the growth of the amorphous area in solid polymer electrolytes (SPEs). Impedance plots show that the uppermost conducting electrolyte had a smaller bulk resistance. The highest attained direct current DC conductivity was 3.01 × 10−3 S/cm for the sample integrated with 50 wt.% of NaI. The dielectric analysis suggests that samples in this study showed non-Debye behavior. The electron transference number was found to be lower than the ion transference number, thus it can be concluded that ions are the primary charge carriers in the MC–NaI system. The addition of a relatively high concentration of salt into the MC matrix changed the ion transfer number from 0.75 to 0.93. From linear sweep voltammetry (LSV), the green polymer electrolyte in this work was actually stable up to 1.7 V. The consequence of the cyclic voltammetry (CV) plot suggests that the nature of charge storage at the electrode–electrolyte interfaces is a non-Faradaic process and specific capacitance is subjective by scan rates. The relatively high capacitance of 94.7 F/g at a sweep rate of 10 mV/s was achieved for EDLC assembly containing a MC–NaI system

Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

Background: Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies. Methods: For this cross-sectional study, we assessed children and adolescents younger than 18 years with a clinical or genetic diagnosis of HeFH at the time of entry into the Familial Hypercholesterolaemia Studies Collaboration (FHSC) registry between Oct 1, 2015, and Jan 31, 2021. Data in the registry were collected from 55 regional or national registries in 48 countries. Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13·0 mmol/L were excluded from this study. Data were assessed overall and by WHO region, World Bank country income status, age, diagnostic criteria, and index-case status. The main outcome of this study was to assess current identification and management of children and adolescents with familial hypercholesterolaemia. Findings: Of 63 093 individuals in the FHSC registry, 11 848 (18·8%) were children or adolescents younger than 18 years with HeFH and were included in this study; 5756 (50·2%) of 11 476 included individuals were female and 5720 (49·8%) were male. Sex data were missing for 372 (3·1%) of 11 848 individuals. Median age at registry entry was 9·6 years (IQR 5·8-13·2). 10 099 (89·9%) of 11 235 included individuals had a final genetically confirmed diagnosis of familial hypercholesterolaemia and 1136 (10·1%) had a clinical diagnosis. Genetically confirmed diagnosis data or clinical diagnosis data were missing for 613 (5·2%) of 11 848 individuals. Genetic diagnosis was more common in children and adolescents from high-income countries (9427 [92·4%] of 10 202) than in children and adolescents from non-high-income countries (199 [48·0%] of 415). 3414 (31·6%) of 10 804 children or adolescents were index cases. Familial-hypercholesterolaemia-related physical signs, cardiovascular risk factors, and cardiovascular disease were uncommon, but were more common in non-high-income countries. 7557 (72·4%) of 10 428 included children or adolescents were not taking lipid-lowering medication (LLM) and had a median LDL-C of 5·00 mmol/L (IQR 4·05-6·08). Compared with genetic diagnosis, the use of unadapted clinical criteria intended for use in adults and reliant on more extreme phenotypes could result in 50-75% of children and adolescents with familial hypercholesterolaemia not being identified. Interpretation: Clinical characteristics observed in adults with familial hypercholesterolaemia are uncommon in children and adolescents with familial hypercholesterolaemia, hence detection in this age group relies on measurement of LDL-C and genetic confirmation. Where genetic testing is unavailable, increased availability and use of LDL-C measurements in the first few years of life could help reduce the current gap between prevalence and detection, enabling increased use of combination LLM to reach recommended LDL-C targets early in life

The RAdio Galaxy Environment Reference Survey (RAGERS) : Evidence of an anisotropic distribution of submillimeter galaxies in the 4C 23.56 protocluster at z=2.48

High-redshift radio(-loud) galaxies (H$z$RGs) are massive galaxies with powerful radio-loud active galactic nuclei (AGNs) and serve as beacons for protocluster identification. However, the interplay between H$z$RGs and the large-scale environment remains unclear. To understand the connection between H$z$RGs and the surrounding obscured star formation, we investigated the overdensity and spatial distribution of submillimeter-bright galaxies (SMGs) in the field of 4C\,23.56, a well-known H$z$RG at $z=2.48$. We used SCUBA-2 data ($\sigma\,{\sim}\,0.6$\,mJy) to estimate the $850\,{\rm \mu m}$ source number counts and examine the radial and azimuthal overdensities of the $850\,{\rm \mu m}$ sources in the vicinity of the H$z$RG. The angular distribution of SMGs is inhomogeneous around the H$z$RG 4C\,23.56, with fewer sources oriented along the radio jet. We also find a significant overdensity of bright SMGs (${\rm S}_{850\rm\,\mu m}\geq5\,$mJy). Faint and bright SMGs exhibit different spatial distributions. The former are concentrated in the core region, while the latter prefer the outskirts of the H$z$RG field. High-resolution observations show that the seven brightest SMGs in our sample are intrinsically bright, suggesting that the overdensity of bright SMGs is less likely due to the source multiplicity

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Impacts of the Tropical Pacific/Indian Oceans on the Seasonal Cycle of the West African Monsoon

The current consensus is that drought has developed in the Sahel during the second half of the twentieth century as a result of remote effects of oceanic anomalies amplified by local land–atmosphere interactions. This paper focuses on the impacts of oceanic anomalies upon West African climate and specifically aims to identify those from SST anomalies in the Pacific/Indian Oceans during spring and summer seasons, when they were significant. Idealized sensitivity experiments are performed with four atmospheric general circulation models (AGCMs). The prescribed SST patterns used in the AGCMs are based on the leading mode of covariability between SST anomalies over the Pacific/Indian Oceans and summer rainfall over West Africa. The results show that such oceanic anomalies in the Pacific/Indian Ocean lead to a northward shift of an anomalous dry belt from the Gulf of Guinea to the Sahel as the season advances. In the Sahel, the magnitude of rainfall anomalies is comparable to that obtained by other authors using SST anomalies confined to the proximity of the Atlantic Ocean. The mechanism connecting the Pacific/Indian SST anomalies with West African rainfall has a strong seasonal cycle. In spring (May and June), anomalous subsidence develops over both the Maritime Continent and the equatorial Atlantic in response to the enhanced equatorial heating. Precipitation increases over continental West Africa in association with stronger zonal convergence of moisture. In addition, precipitation decreases over the Gulf of Guinea. During the monsoon peak (July and August), the SST anomalies move westward over the equatorial Pacific and the two regions where subsidence occurred earlier in the seasons merge over West Africa. The monsoon weakens and rainfall decreases over the Sahel, especially in August.Peer reviewe