11 research outputs found

    Current knowledge and future perspectives of barrier membranes: A biomaterials perspective

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    Periodontal regenerations and bone augmentations are common procedures practiced on a daily basis worldwide. This had led to the introduction of a wide number of barrier membranes, all aiming at regenerating a sufficient amount of bone while being safe, cost effective and easy to handle. Membranes have different characteristics that may influence their clinical properties and the result obtained. The article aims at presenting an overview of the different barrier membranes commonly used in the oral surgery field, while shedding light on the new advances in the third generation membranes

    Effect of Supportive Periodontal Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-smokers: A Systematic Review

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    Aim: The aim of this systematic review is to analyze and compare tooth loss (TL) rates between regular and irregular compliant patients having different smoking habits. Materials and Methods: Electronic and manual literature searches were conducted by one author in several databases, including Medline (PubMed), Embase, Google Scholar. A total of 156 publications were screened. Three reviewers analyzed the articles and extracted the data. A total of 33 studies met the inclusion criteria. Results: A total of 30 articles were eligible for qualitative analysis, and only 3 for quantitative analysis. Compliance and smoking case definition as well as recall intervals during supportive periodontal therapy (SPT) differed widely between studies. A total of 10 publications reported significant differences in TL rates between regular (RC) and irregular compliant (IC) patients, while 25 publications reported significant differences in TL rates between smokers and non-smokers. Conclusion: Regular attendance to SPT visits and non-smoking patients are associated with fewer TL rates. Smoking is considered a major modifiable risk factor for TL

    Bone regeneration using deproteinized bovine bone mineral (DBBM) in a crestal sinus elevation technique: a histological and histomorphometrical pilot study

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    The aim of this study is to evaluate the percentage of new bone formation (NBF) and residual bone substitute following the use of a bovine demineralized xenograft (DBBM) in a sinus floor crestal approach elevation technique

    Clinical and radiographic evaluation of bone remodeling around implants placed in horizontally augmented bone: A pilot study

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    Introduction: Marginal bone loss after implant placement is one of the most used criteria to assess the success of osseointegrated implants over time. The type of implant connection and implant surface type are reported to have an influence on bone remodeling around the placed implants. This study aimed to evaluate marginal bone loss around two implant systems with different connections and surfaces in horizontally augmented sites. Methods: This randomized control pilot study included 8 implants placed in 3 patients who needed implant placement in previously horizontally grafted sites. The placed implants were divided into two groups: group 1 consisting of implants with external connection and a hybrid design, and group 2 including implants with an internal connection and a fully etched surface. Clinical and radiographical measurements were taken at baseline, during the surgery, and up to one year after loading to evaluate marginal bone loss around the two different implants placed in grafted sites. Results: All implants were retained at all follow-up periods and healing was uneventful. There were similar Marginal Bone Loss (MBL) and soft tissue changes around both types of implants. Group 2 implants had higher MBL, however, the difference was not statistically significative. Conclusion: Preliminary analysis suggest that full surface etching does not seem to negatively influence marginal bone loss around implants placed in augmented bone

    Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

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    PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

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    PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Current knowledge and future perspectives of bone replacement grafts

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    Bone and periodontal regenerative procedures represent a fundamental component of periodontal practice. While autologous bone graft has always been considered the ideal material for the repair and/or reconstruction of craniofacial defects, its limited availability and harvesting-associated complications and discomfort lead to asubstantial interest in bone replacement grafts (BRG) throughout the years. With increasing technological advances and understanding, the spectrum of BRG has broadened and taking into consideration that not all BRM perform in the same way, the appropriate clinical choice needs to be performed among the large varieties ofavailable biomaterials. Because an understanding of the properties of each BRG enables individualized clinical selection, the objective of this article is to provide a review on the different types of BRG intended for reconstructive therapy and provide an overview on the current innovations and future perspectives in this field

    Elective Cancer Surgery in COVID-19–Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

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    Delaying surgery for patients with a previous SARS-CoV-2 infection

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