9 research outputs found
Lymphocytes possess an electrogenic H+-transporting pathway in their plasma membrane
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- 'Portland Press Ltd.'
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- Field of study
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
- Author
- 14 | COVIDSurg COllabOratIVe Tzovaras G. (General University Hospital of Larissa)
- Aawsaj Y.
- Abad Gurumeta A.
- Abad-Motos A.
- Abate E.
- Abbott D.
- Abdalla M.
- Abdeldayem H.
- Abdelkader Salama I.
- Abdelkarim M.
- Abdur-Rahman L.
- Abel M. K.
- Aboelkassem Ibrahim A.
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- Abreu da Silva A.
- Abubakar A.
- Acebes GarcĂa F.
- Achalandabaso Boira M. Sales Mallafré R. (Hospital Universitari de Tarragona Joan XXIII)
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- Adamina M.
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- Adiamah A.
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- Agapov M.
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- Aguado H. (HellĂn Hospital)
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- Alma Mater Studiorum University of Bologna)
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- Argentina: Alurralde C.
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- COVIDSurg COllabOratIVe | 15 Violante T. (IRCCS Azienda Ospedaliero â Universitaria di Bologna
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- Department of Biomedical Sciences
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- Government Medical College). Ireland: Aremu M.
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- TU Dresden)
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- Universiti Sains Malaysia)
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- Velchuru V.
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- Velidedeoglu M.
- Venn M. (Royal London Hospital)
- Venskutonis D. (Lithuanian University of Health Sciences Kaunas Clinical Hospital). Madagascar: Rasoaherinomenjanahary F.
- Vera Mansilla C. (Hospital Universitario Principe de Asturias)
- Verberne C. (John Radcliffe Hospital)
- Vergari R. (Ospedali Riuniti di Ancona)
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- Vezakis A. (Aretaieion Hospital)
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- Vieira B. (Centro Hospitalar de TrĂĄs-Os-Montes e Alto Douro
- Vieira Caroço T. (IPO Coimbra)
- Vieira Paiva Lopes A. C. (Hospital de Torres Vedras â Centro Hospitalar do Oeste)
- Vignali A. (San Raffaele Scientific Institute
- Vigorita V. (Ălvaro Cunqueiro Hospital)
- Vijayan D. (Queen Elizabeth Hospital Birmingham)
- Villalabeitia Ateca I. (Hospital Universitario Cruces)
- Vimalachandran D. (Countess of Chester Hospital)
- Viswanath Y. K. S. (James Cook University Hospital)
- Vitali A. (Ospedale San Giovanni di Dio)
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- Von Papen M.
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- Wadham B. (The University Hospital of South Manchester)
- Walkes K. (Queen Elizabeth Hospital). Belgium: Flamey N.
- Wani R. (Sher-I-Kashmir Institute of Medical Sciences)
- Waqar S. H. (Pakistan Institute of Medical Sciences). Poland: Major P. (Jagiellonian University Medical College). Portugal: Azevedo C.
- Warren O. (Chelsea and Westminster Hospital)
- Watson L. J. (Sunderland Royal Hospital)
- Watson N. (Kingâs Mill Hospital)
- Weitz J.
- Welsch T. (Carl-Gustav-Carus University Hospital
- Werner J. (LMU Klinikum Campus Innenstadt)
- Westwood E. (James Paget University NHS Foundation Trust Hospital)
- Whelan M. (Tallaght University Hospital)
- Whitmore H. (Torbay and South Devon NHS Trust)
- Wilkin R. J. W. (South Warwickshire NHS Foundation Trust)
- Wilkins A. (Hull University Teaching Hospitals NHS Trust)
- Williams G. (Royal Gwent Hospital)
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- Xavier R. G.
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- Yang W.
- Yassin N. (Royal Wolverhampton NHS Trust)
- Ye G.
- Yesantharao P.
- Yetkin S. G. (Sisli Hamidiye Etfal Training and Research Hospital)
- YeĆilyurt D. (University of Health Sciences Tepecik Training and Research Hospital)
- Yiallourou A. (Nicosia General Hospital). Czechia: Martinek L.
- Yıldırım A.
- Yildiz A. (Yildirim Beyazit University Yenimahalle Training and Research Hospital). Uganda: Lule H.
- Young R. (York Teaching Hospitals NHS Trust)
- Yousof E. A. (Assiut University Hospital)
- Youssef M. (Norfolk and Norwich University Hospital)
- Yurttas C. (University Hospital Tuebingen)
- YĂĄnez C. (Royo Villanova)
- YĂŒksel E. (Kocaeli University Teaching Hospital)
- Zafar S. N. (University of Wisconsin)
- Zakaria A. D.
- Zakaria Z. (School of Medical Sciences and Hospital
- Zambon M. (Policlinico Umberto I Sapienza University of Rome)
- Zanus G. (Caâ Foncello Treviso â DISCOG â UniversitĂ di Padova)
- Zegarac M. (Institute for Oncology and Radiology of Serbia)
- ZeliÄ M. (University Hospital Center Rijeka)
- Zengin A. K. (Istanbul Universty â CerrahpaĆa Medical Faculty)
- Zerbib P. (CHU Lille)
- Zervas K.
- Zese M. (Santa Maria degli Angeli Hospital ULSS 5 â Adria)
- Zhang H. (Concord Repatriation General Hospital)
- Zizzo M. (Azienda UnitĂ Sanitaria Locale â IRCCS di Reggio Emilia)
- Zografos C. (Laiko University Hospital)
- Zorrilla OrtĂșzar J. (Hospital General Universitario Gregorio Marañón)
- Zourntou S. (General Hospital of Larissa âKoutlimpaneio and Triantafylleioâ)
- Zubaidi A. M. (King Saud University). Serbia: AleksiÄ L.
- Ăngelo M.
- Ăelebi F.
- Ăolak E.
- Ăfner D. (Medical University of Innsbruck)
- Ăhlberger L.
- Ăzçelık M. F.
- ĂÄĂŒcĂŒ H.
- ĂberrĂŒck L.
- Äoza I.
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic
Regulation of the electrogenic H+ channel in the plasma membrane of neutrophils: possible role of phospholipase A2, internal and external protons
- Publication venue
- 'Portland Press Ltd.'
- Publication date
- Field of study
Delaying surgery for patients with a previous SARS-CoV-2 infection
- Author
- A A Ali Karar
- A A Kerawala
- A A Marra
- A Abad Gurumeta
- A Abad-Motos
- A Abdelmajeed
- A Abdelrahman
- A Abdelsamed
- A Abdulkareem
- A Aboelkassem Ibrahim
- A Abouassi
- A Abreu da Silva
- A Abubakar
- A Acher
- A Aderombi
- A Adeyeye
- A Adiamah
- A Aggarwal
- A Aghayeva
- A Agnes
- A Agrawal
- A Ahmeidat
- A Aimé
- A Ajlan
- A Al-Habib
- A Al-Mohammad
- A Al-Mukhtar
- A Aladeojebi
- A Alamri
- A Alanbuki
- A Alatar
- A Alburakan
- A Alfaro-Goldaracena
- A Alhamed
- A Alhefdhi
- A Almeciga
- A Almeida
- A Alomair
- A Alonso Poza
- A Alsaif
- A Anastasi
- A Antic
- A Anzak
- A Aprile
- A Arminio
- A Arulanantham
- A Askari
- A Asqalan
- A Athanasiou
- A Ayhan
- A Ayman
- A Ayubi
- A Azizi
- A B Martins
- A Bacon
- A Baker
- A Balakrishnan
- A Bandiera
- A Banerjee
- A Barrabe
- A Beamish
- A Bellacci
- A Belli
- A Belvedere
- A Benkabbou
- A Bhalla
- A Bhangu
- A BillĂš
- A Bin Nasser
- A Biondi
- A Blatt
- A Blazquez Martin
- A Boddy
- A Bokhari
- A Bondurri
- A Boulton
- A Boutall
- A Branquinho
- A Brunelli
- A Brunt
- A Bruscino
- A Budacan
- A Burahee
- A Böttcher
- A C Almeida
- A C Deus
- A C Roslani
- A C Soares
- A C Vieira Paiva Lopes
- A Caiado
- A Camillo
- A Canas-Martinez
- A Cano
- A Carabias
- A Chandock
- A Charalabopoulos
- A Che Jusoh
- A Chebaro
- A Chessa
- A Chiappini
- A Chitul
- A Choudhry
- A Chowdhury
- A Colquhoun
- A Conesa
- A Cordova
- A Costanzi
- A Cotoia
- A Cotter
- A Crichton
- A Cuadrado-GarcĂa
- A Currie
- A Cvetkovic
- A D Bueno Cañones
- A D Rajgor
- A D Zakaria
- A D'Amore
- A D'Urso
- A Daly
- A Davies
- A Day
- A De Gea Rico
- A De Manzoni Garberini
- A De Pablo GarcĂa-Cuenca
- A De Troia
- A De Virgilio
- A Dehal
- A Desai
- A Di Bartolomeo
- A Di Bella
- A Di Somma
- A Diamantis
- A Doyle
- A Durrani
- A E Arikan
- A E Sherif
- A Eastmond
- A El Ouahabi
- A Elawad
- A Eldaly
- A Elhamshary
- A Esposito
- A Esteban
- A Ezanno
- A Fadzli
- A Fagotti
- A Fancellu
- A Farsi
- A Faustino
- A Fazenda
- A FernĂĄndez-LĂłpez
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- A Ferrés
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- A I Tercero-Uribe
- A Ibrahim
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- A Khan
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- A Kirk
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- A Koh
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- A KollĂ r
- A Kolusarı
- A Kourdouli
- A Kouyoumdjian
- A Kredan
- A Kumar
- A Königsrainer
- A L De Oliveira LĂłpez
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- A Laforest
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- A Laird
- A Landaluce-Olavarria
- A Lanzon
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- A Lauretta
- A Lim
- A Loayza
- A Loehrer
- A Lopez Abad
- A Louvrier
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- A Lyons
- A LĂĄzaro
- A LĂłpez Campillo
- A M Abbas
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- A M Lacy
- A M Majbar
- A M Minaya Bravo
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- A M Pathanki
- A M Perrone
- A M Scanu
- A Macchi
- A Madhavan
- A Madkhali
- A Maffioli
- A Maffuz-Aziz
- A Maghrabi
- A Maiga
- A Majkowska
- A Mansuri
- A Mantevas
- A Marano
- A Marchbank
- A Marco Garrido
- A Margalit
- A Martin-Ucar
- A Martinez German
- A Marçal
- A Mashat
- A Maw
- A McCanny
- A Mccarthy
- A McLennan
- A McMillan
- A Melo
- A Menon
- A Merchan
- A Merdrignac
- A MiljkoviÄ
- A Millan
- A Mingoli
- A Minicozzi
- A Mirabella
- A Modabber
- A Mohammad
- A Moro
- A Morris
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- A Morton
- A Mosca
- A Moumen
- A Muratore
- A Mustafa
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- A Nabil
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- A Nawawi
- A Nobre Pinto
- A Nogués
- A Oar
- A Oliveira
- A Osorio
- A Otero
- A Ovaitt
- A P Ferreira Pinto
- A P Pezzuto
- A Parello
- A Parente
- A Parseliunas
- A Patel
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- A Paunovic
- A Pearce
- A Pereira
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- A Peryt
- A Petrillo
- A Piras
- A Pisani Ceretti
- A Pisanu
- A Polydorou
- A Popoola
- A Porcu
- A Provozina
- A Pucar
- A PĂ©rez NĂșñez
- A Qasem
- A Quennell
- A Qureshi
- A Ramachandran
- A Ramos Bonilla
- A Ramwell
- A Ribeiro
- A Rizzi
- A Robinson
- A Robson
- A Rodolakis
- A Rodrigues
- A Rodriguez Fraga
- A Rogers
- A Rogers
- A Romero de Diego
- A Rowcroft
- A Ruivo
- A Ruiz Escobar
- A Ruzzenente
- A S Bodla
- A S Coonar
- A S Crugnale
- A S Memon
- A S Mohamed Sidek
- A S Yahaya
- A Sabry
- A Sachdeva
- A Sagnotta
- A Said Bayazeed
- A Salamah
- A Salazar
- A Saleem
- A Samih
- A Samir Abdelaal
- A Samkari
- A Samy
- A Santoro
- A Sanz Larrainzar
- A Saratziotis
- A Sarin
- A Sayasneh
- A Scalabre
- A Schache
- A Seguin-Givelet
- A Seleim
- A SgrĂČ
- A Shabana
- A Sharkey
- A Sharma
- A Sheel
- A Shenfine
- A Sherif
- A Shuwayyah
- A Singh
- A Soares
- A Solth
- A Souadka
- A Spinelli
- A Ssentongo
- A Stanimirovic
- A Stavroglou
- A Stefanovic
- A Stepanyan
- A Subocius
- A Sultana
- A Sutherland
- A Syllaios
- A SĂĄnchez-Pernaute
- A Taddei
- A Taibi
- A Tailor
- A Tang
- A Tedde
- A Thomas
- A Thompson
- A Tojal
- A Tooulias
- A Torne
- A Torres
- A Townson
- A Trivic
- A Tufo
- A Turnbull
- A Urbani
- A Urbieta
- A Usai
- A Valente da Costa
- A Vallance
- A Valle Rubio
- A Varazzani
- A Vazquez Fernandez
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- A Wali
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- A Woodham
- A Y Azzam
- A Yiallourou
- A Yıldırım
- A Yildiz
- A Youssef
- A Zubaidi
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- A ĂlgĂ„
- Abd Elazeem Has
- Abhinav Tiwari
- Abigail Vallance
- Adesoji Ademuyiwa
- Adesoji O Ademuyiwa
- Adrian Marchbank
- Ahmad Qureshi
- Akshay Patel
- Alan McNeill
- Alessandro Brunelli
- Alessandro Gronchi
- Alex Alamri
- Alex Wilkins
- Alexandra Colquhoun
- Alexis P Arnaud
- Aman S Coonar
- Amanpreet Brar
- Ana Minaya-Bravo
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- Ana Minaya-Bravo
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- Anant Desai
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- Andreas A Schnitzbauer
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- Andrey Litvin
- Aneel A Bhangu
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- Angelos Kolias
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- Anna Fagotti
- Antonino Spinelli
- Antonio Ramos-De la Medina
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- Arda Isik
- Arnav Agarwal
- B A Fahey
- B Al-Sarireh
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- B Alhassan
- B Ayub
- B B Ozmen
- B Baca
- B Bakmaz
- B Banky
- B Barmayehvar
- B Barrat
- B Bartalucci
- B Bozkırlı
- B Brown
- B Caimari
- B Challacombe
- B Chumbinho
- B Cimenoglu
- B Cirillo
- B Citgez
- B Collard
- B Costeira
- B Cros
- B Davidson
- B De Andrés Asenjo
- B De Simone
- B Devauchelle
- B Dias
- B Diéguez
- B DĂaz-Feijoo
- B El Ahmadi
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- B Giray
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- B Jayasankar
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- B Lieske
- B Malgras
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- B PĂ©rez-Saborido
- B Rai
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- B Seeliger
- B Sheu
- B Soyak
- B Steel
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- B Tadic
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- B Vieira
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- C Bergamini
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- C Bezede
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- C Burgess
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- C Donohue
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- Costa Mjma
- D A Raptis
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- Willemijn van der Plas
- Wong Mpk
- X De Sousa
- X Morales
- X S Tan
- Y Aawsaj
- Y Al-Tamimi
- Y Arkha
- Y Ayasra
- Y Bashir
- Y El Bouazizi
- Y Fayed
- Y H Lam
- Y Kanemitsu
- Y Kara
- Y Kirmizi
- Y Levy-Zauberman
- Y Litvina
- Y Perez
- Y T Liew
- Y Tanase
- Y Viswanath
- Y Ying
- Z Al-Ishaq
- Z Aldayri
- Z Aliyeva
- Z Bayhan
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- Z Inic
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- Z Mahasin
- Z Seymour
- Z Vilendecic
- Z Zakaria
- Ă De la Hoz RodrĂguez
- à Fernåndez Camuñas
- Ă Ryan
- Ćœ GrubaÄ
- Đ ĐĐ°ĐŒĐ°Đ»ĐŸĐČ
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Not availabl
Elective Cancer Surgery in COVID-19âFree Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study
- Author
- Aawsaj Y
- Abad Gurumeta A
- Abad-Motos A
- Abate E
- Abatini C
- Abbadessa F
- Abbas AM
- Abbassi-Ghadi N
- Abbott D
- Abbott T
- Abbott Tom EF
- Abd Elazeem HAS
- Abdalla M
- Abdallah M
- Abdel Al S
- Abdel Jalil R
- Abdeldayem H
- Abdelkader Salama I
- Abdelkarem MM
- Abdelkarim M
- Abdelmajeed A
- Abdelrahman A
- Abdelrahman S
- Abdelsamed A
- Abdou M
- Abdulkareem A
- Abdulwahed E
- Abdur-Rahman L
- Abel MK
- AbellĂĄn M
- Aboelkassem Ibrahim A
- Abosamak NE
- Abou Chaar MK
- Abou Chaar Mohammad K.
- Abou-Khalil J
- Abouassi A
- Aboulkassem H
- Abreu da Silva A
- Abu Zaânouneh FJ
- Abu J
- Abu-Nayla I
- Abubakar A
- Abukhalaf Sadi
- Acebes GarcĂa F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina Michel
- Adamoli L
- Addae-Boateng E
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adiamah A
- Adishesh M
- Agapov M
- Agarwal Arnav
- Aggarwal A
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agoston P
- Agrawal A
- Agresta F
- Aguado H
- Aguilar Gonzalez M
- Aguzzoli L
- Ahad S
- Ahmadi N
- Ahmeidat A
- Ahn JH
- Aiken T
- Aimé A
- Ajlan A
- Akalin M
- Akaydin E
- Akeel N
- Akgor U
- Akhtar MA
- Akhter Rahman MM
- Akilli H
- Akin E
- Akkour K
- Akkulak Murat
- Akmenkalne L
- Al Abdallah M
- Al Awwad S
- Al Habes H
- Al Maadany FS
- Al Raddadi R
- AL Sayed M
- Al-Habib A
- Al-Habsi R
- Al-Ishaq Z
- Al-Khayal K
- Al-Masri M
- Al-Mohammad A
- Al-mukhtar A
- Al-Najjar H
- Al-omishy H
- Al-Sarireh B
- Al-Tamimi Y
- Alaa S
- AlAamer O
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- Alakaloko Felix
- Alam F
- Alam N
- Alam R
- Alameer Ehab
- Alamri A
- Alamri Alex
- Alanbuki A
- Alatar A
- Alawneh F
- Alazawi D
- Albertsmeier M
- Albertsmeiers Markus
- Albi Martin B
- Alburakan A
- Alcaide Matas F
- Alconchel F
- Aldayri Z
- Aldecoa Ansorregui I
- Alderson Derek
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- AleksiÄ L
- Alemanno G
- Alexoudi V
- Alfaro-Goldaracena A
- Alfieri S
- Alghamdi M
- Alhalal H
- Alhamed A
- Alharthi M
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- Aliyeva Z
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- Alshaar Muhammad
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- Alshareea E
- Alsharif F
- Alshaygy I
- Alshryda Sattar
- Alsobhi S
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- on behalf of the COVIDSurg Collaborative
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- Zouzoulas D
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- Zullo A
- Ăngelo M
- ĂlgĂ„ A
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- Ăelebi F
- Ăolak E
- Ăfner D
- Ăhlberger L
- ĂÄĂŒcĂŒ H
- ĂberrĂŒck L
- Äoza I
- Ć imko K
- Ć ÄepanoviÄ V
- ĆœateckĂœ J
- ĐĐ°ĐŒĐ°Đ»ĐŸĐČ Đ
- Publication venue
- American Society of Clinical Oncology
- Publication date
- 01/01/2021
- Field of study
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Aawsaj Y
- Abadia M
- AbadâGurumeta A
- AbadâMotos A
- Abassy J
- Abate E
- Abbasov A
- Abbott D
- Abbott Tom EF
- Abdalla M
- Abdeldayem H
- Abdelkabir M
- Abdelkader Salama I
- Abdelkarim M
- Abdelsamed A
- Abdulfattah F
- Abdulwahed E
- AbdurâRahman LO
- Abel MK
- Abelevich A
- Abiyere H
- Aboelkassem Ibrahim A
- Aboharp Hasan Z
- Abou Chaar MK
- Abreu da Silva A
- Abubakar A
- Abukhalaf SA
- Abukhalaf Sadi
- Acebes GarcĂa F
- Achalandabaso Boira M
- Acher A
- Acosta MĂ©rida MA
- Acrich E
- Adam Essa Adam ME
- Adamina M
- Adamina Michel
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adeyeye A
- Adi H
- Adiamah A
- Adisa Adewale
- Afzal MF
- Agapov M
- Agarwal Arnav
- Aggarwal M
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguado LĂłpez H
- Aguiar JĂșnior S
- Aguilar Gonzalez M
- Ahmed A
- Ahmed A
- Ahmed K
- Ahmed ME
- Ahmed Z
- Ahmeidat A
- Ahn JH
- Aiken T
- Aimé A
- Akalin M
- Akaydin E
- Akbas A
- Akhtar MA
- Akhtar N
- Akhter Rahman MM
- Akin E
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al ahmad F
- Al Asadi T
- Al Awwad S
- Al Ayed A
- Al Habes H
- Al Riyami S
- AL Sayed M
- Alaa S
- AlAamer O
- Aladeojebi A
- Alagoa Joao A
- Alakaloko Felix
- Alam F
- Alameer Ehab
- Alamri Alex
- Alanazi F
- Alawneh F
- Albaqami F
- Albertsmeier M
- Albertsmeier Markus
- Alcaide Matas F
- Alconchel F
- AlcĂĄzar JA
- Alderson Derek
- Aldokali N
- AleksiÄ L
- Alemanno G
- Alfaifi J
- Alfieri S
- Alfonso Garcia M
- Algallai M
- Alghamdi M
- Alghuliga A
- Alhamed A
- Alharthi M
- Alhassan N
- Ali karar AA
- Ali Sani S
- Ali AA
- Ali M
- Ali S
- Alishi Y
- Aliyeva Z
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- Alkadiki Ghadah Z
- Alkhateb S
- Allue M
- Almaadany Faraj S
- Almassaudi A
- Almeida AC
- Almeida JI
- AlmeidaâReis R
- Almezghwi H
- Almgla N
- Almond Max
- Alnumani T
- Alobaysi S
- Alobeed O
- Alonso de la Fuente N
- Alonso Poza A
- AlonsoâLamberti L
- Alqahtani D
- Alqannas M
- Alrahawy M
- Alsayadi M
- Alsayadi R
- Alselaim N
- Alser Osaid
- Alshaar Muhammad
- Alshahrani A
- Alshahrani M
- Alshammari S
- Alshareea E
- Alshareef K
- Alsharif F
- Alshryda Sattar
- Alsoufi A
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- Altomare DF
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- Alurralde C
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- Alvarez MR
- Alvi A
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- Alzaede S
- Alzahrani A
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- Alzeerelhouseini H I. A.
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- Amaral MJ
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- Anania G
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- Angelou D
- Angenete E
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- Annamalai S
- Annessi V
- Annicchiarico A
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- Antic A
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- Arulanantham A
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- Ashcroft J
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- Ashoush F
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- Athanasiou A
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- Attia D
- Augestad Knut Magne
- Avci EK
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- Ayasra Faris
- Ayasra Y
- Aydin C
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- Ayorinde J
- Aytac E
- Ayub B
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- Azevedo C
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- Babalola O
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- Badahdah F
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- Baig M
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- BaiĂŁo JM
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- Balasubramaniam D
- Balconi A
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- Banky B
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- Barisic G
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- Barlow C
- Barlow Emma
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- Batstone Martin
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- Biel Juan Rey
- Bigam D
- Bigelow B
- Bilgin IA
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- Birolo SL
- Bisagni P
- Bisset C
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- Bozkurt E
- Bozkurt MA
- Brachini G
- Bradulskis S
- Braham H
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- Bravo Ana Minaya
- Breen Kerry A
- Bretherton Chris
- Brewer H
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- Brixton G
- Brocklehurst M
- Bromage Steve
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- Burke Joshua
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- Bywater Edward
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- Camacho C
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- Camarneiro R
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- Cano A
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- Cantalejo diaz M
- Capelli P
- Capezzuoli L
- CapitanâMorales L
- Capkinoglu E
- Capolupo GT
- Capunge I
- CarabiasâOrgaz A
- Caram EL
- Carannante F
- Carbone F
- Carcoforo P
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- Cardoso P
- Carissimi F
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- Carvalho Ferro C
- Carvello MM
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- Castro Ruiz C
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- Catena F
- Cato LD
- Cayetano Paniagua L
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- Cennet O
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- Cerro Zaballos C
- Cervellera M
- Cervera I
- Cha DE
- Chaar Mohammad
- Chadha R
- Chakrabortee Sohini
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- Chan E
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- Charalabopoulos A
- Charre L
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- Chaturvedi A
- Chaturvedi H
- Chatzikomnitsa P
- Chaudhry Daoud
- Chavarrias N
- Che jusoh A
- Chean CS
- Chebaro A
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- Chen S
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- Chessa A
- Cheung J
- Cheung LK
- Chevallay M
- Chia Z
- Chiappini A
- Chiarugi M
- Chinda J
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- Chitul A
- Chiva Luis
- Chokshi R
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- Choong E
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- Chowdhury A
- Chowdhury S
- Chowdri N
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- Christensen Peter
- Christidis P
- Christoforidis D
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- Chumbinho B
- Chung E
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- Cianflocca D
- Cicerchia PM
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- Ciofic E
- Cirillo B
- Cirocchi N
- Ciubotaru C
- Clarizia G
- Claro M
- Clifford R
- Coccolini F
- Cocozza E
- Coffey JC
- Cohen Paul
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- Zakaria Z
- Zakharenko A
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- Zengin AK
- Zerbib P
- Zervas K
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- Zhang H
- Zizzo M
- Zmora O
- Zografos C
- Zonta S
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- Zourntou S
- Zubaidi A
- Ăngelo M
- ĂlgĂ„ A
- Ăelebi F
- Ăolak E
- Ăfner D
- Ăhlberger L
- Ăzant A
- Ăzçay N
- ĂÄĂŒcĂŒ H
- ĂberrĂŒck L
- Äoza I
- Ćawnicka A
- ĆœateckĂœ J
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4âweeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4âweeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, PÂ =Â 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, PâConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries
- Author
- Aarts Frits
- Ababneh Hazim
- Abad-Motos Ane
- Abaidalla Ahmed
- Abbakar Malaz
- Abd El Aal Ahmed
- Abd-Errazik Mohammad Ahmad
- Abdalradiy Abdalrahmman G
- Abdelkhalek Mohamed
- Abdelkhalek Mostafa
- Abdellatif Ahmed
- Abdellatif Mohamed
- Abdelsaid Kirolas
- Abdou Khaled
- Abdulfatah Mustapha
- Abdullah Mohammad Amer
- Abdullahi Mustapha Miko Mohammed
- AbellĂĄn Antonio Melero
- Abeysinghe Nayana
- Abiyere Henry
- Achimas-Cadariu Patriciu Andrei
- Adakaya Sıla
- Adam Nicolas
- Adams Benita
- Adams Ferdinand
- Adegboye Kazeem
- Adeyeye Ademola
- Adra Lama
- Adu-Poku Patricia
- Afuwape Oludolapo
- Afzal Ameer
- Afzal Muhammad Farooq
- Agapov Mihail
- Agara Daniel
- Aggarwal Manisha
- Agger Erika
- Aghadi Ifeanyi Kene
- Ahmed Amjed Yassir
- Ahmed Haleemasahdia
- Ahmed Khalil
- Ahmed Manar
- Ahmed Masood
- Ahmed Safia
- Ahn Hong Min
- Aibe Raquel
- Aigner Felix
- Aissat Abdenour
- Aitbaeva Arai
- Akay Omer
- Akbar Ali
- Akbas Ahmet
- Akere Abidemi
- Akesen Selcan
- Akgun Erhan
- Akhtar Naseem
- Akın Emrah
- Akova Elif
- Aktas Serhat
- Akçay Ăzlem
- Al Masri Mahmoud
- Al-Alnsi Ahmed
- Al-Hutheifi Roqia'A
- Al-Jarrah Amar
- Al-Naggar Hamza
- Al-Shehari Mohammed
- Alamin Nadeen
- Alawi Raneen
- Alawlaqi Dina
- Alawneh Fade
- Alberola Maria José
- Albers Michael
- Alcolea Natalia GonzĂĄlez
- Aleem Muhammad
- Alegre InĂȘs
- Alegre Javier Martinez
- Alexandre Flavia
- Alexandrescu Corina
- Alexnder Abelevich
- Alexopoulou Kalliopi
- Alfonso Beatriz AmorĂłs
- Ali Ahmed
- Ali Che Saniati Che
- Ali Danish
- Ali Madeeha
- Ali Mahmoud Abdelwahab
- Ali Manhal Hashim
- Ali Noura Al
- Alikhanli Jhale
- Aliyeva Zumrud
- Aliyu Mohammed
- Aljawder Hasan
- Allen Kate
- Almahmeed Ebrahim
- Alonso Alfredo
- Alonso Javier Etreros
- Alsamneh Muneer
- Alsayadi Ramzi
- Altinel Yuksel
- Altintoprak Fatih
- Altomare Donato F
- Alvarenga Isabella
- Alvarez Laura Jimenez
- Alvarez-Bautista Francisco Emmanuel
- Alvarez-DĂez Marcos
- Alves Brenda Chayanny
- Amadigwe Rita
- Amado Andreia
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- Knowles Charles H
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- Ulasi Ikechukwu
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- Umar Nura Aliyu
- Umberto Casiraghi
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- Uranitsch Stefan
- Utkan Nihat Zafer
- Vacca Cristina
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- Vasale Alessandro
- Vasiukova Evgeniia-Surgeon
- Vassiliu Pantelis
- Vaughan-Shaw Peter G
- Vecchio Pablo
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- Veetil Sreejith Kannummal
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- Wilson Jeremy
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- Yakunina Natalia
- Yalkin Ămer
- Yanishev Alexey
- Yao Hongwei
- Yazici Pinar
- Yemez Kursat
- Yew Chor Kuan
- Yılmaz GĂŒlseren
- Yilmazlar Tuncay
- YiÄit Direnç
- Yoldas Tayfun
- Yonekura Hiroshi
- Yorkmui Liu
- Yoshino Kenji
- Younes Lina
- Young Trudi
- Yule Michael
- Yusoff Zakiah Mohd
- Zaari Fatimazahraa
- Zabiyaka Mikhail
- ZadroĆŒna Monika
- Zafar Madiha
- Zagaynov Eugeny
- Zaidi Syed-Nadeem
- Zaimis Tilemachos
- Zain Wan Zainira Wan
- Zainy Rhendra Hardy Mohamad
- Zakaria Andee Dzulkarnaen
- Zakaria Maheen
- Zakaria Zaidi
- Zamudio-Bautista Jorge Luis
- Zanc Loredana
- Zanoni Andrea
- Zanus Giacomo
- Zapparoli Alessandro
- Zappone Anna
- Zarzava Eirini
- Zatari Dirar
- Zawadzki Marek
- Zayakov Georgi
- Zaycev Andrey
- Zazo Aya
- Zazo Rama
- Zdravkovic Maja
- Zengin Abdullah KaÄan
- Zeringa Georgia
- Zimmerman David D E
- Zuhdy Mohammad
- Zvirych Vitalii
- Zywicka Ewa
- Ălvarez-Llano Laura
- Ăngelo Miguel Duarte
- ĂSullivan Sara Nuñez
- Ăzçelik Mehmet Faik
- Äoza Ivo
- Ćanlı Ahmet Necati
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background
Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks.
Methods
The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned.
Results
A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P < 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31).
Conclusion
Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)