Idiopathic adrenal hematoma mimicking neoplasia: A case report

AbstractIntroductionAdrenal haemorrhage is a relatively rare condition. If there is not a specific ethology describing adrenal hematoma, then, this is termed as ‘idiopathic adrenal hematoma’.Presentation of caseWe presented a case of idiopathic adrenal hematoma in this study. A 62-year-old woman was referred to our hospital for evaluation of a 40mm mass in the left upper abdominal cavity. The histopathological findings of the surgical specimen revealed a hematoma with normal adrenal tissue.DiscussionThe incidence of adrenal haemorrhage was found to be 1.1% regarding autopsy results. The Adrenal gland is highly vascular and vulnerable to haemorrhage. Before a surgical operation, it is difficult to diagnose idiopathic adrenal hematomas.ConclusionAn adrenal hematoma should be kept in mind when adrenal masses assessing

Branching on multi-aggregated variables

open5siopenGamrath, Gerald; Melchiori, Anna; Berthold, Timo; Gleixner, Ambros M.; Salvagnin, DomenicoGamrath, Gerald; Melchiori, Anna; Berthold, Timo; Gleixner, Ambros M.; Salvagnin, Domenic

Formal Analysis of Distance Bounding with Secure Hardware

A distance bounding (DB) protocol is a two-party authentication protocol between a prover and a verifier which is based on the distance between the prover and the verifier. It aims to defeat threats by malicious provers who try to convince that they are closer to the verifier or adversaries which seek to impersonate a far-away prover. All these threats are covered in several security definitions and it is not possible to have a single definition covering all. In this paper, we describe a new DB model with three parties where the new party is named hardware. In this model, called secure hardware model (SHM), the hardware is held by the prover without being able to tamper with. We define an all-in-one security model which covers all the threats of DB and an appropriate privacy notion for SHM. In the end, we construct the most efficient (in terms of computation by the prover-hardware and number of rounds) and secure DB protocols achieving the optimal security bounds as well as privacy

Fabrication of vertically aligned Pd nanowire array in AAO template by electrodeposition using neutral electrolyte

A vertically aligned Pd nanowire array was successfully fabricated on an Au/Ti substrate using an anodic aluminum oxide (AAO) template by a direct voltage electrodeposition method at room temperature using diluted neutral electrolyte. The fabrication of Pd nanowires was controlled by analyzing the current–time transient during electrodeposition using potentiostat. The AAO template and the Pd nanowires were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) methods and X-Ray diffraction (XRD). It was observed that the Pd nanowire array was standing freely on an Au-coated Ti substrate after removing the AAO template in a relatively large area of about 5 cm2, approximately 50 nm in diameter and 2.5 μm in length with a high aspect ratio. The nucleation rate and the number of atoms in the critical nucleus were determined from the analysis of current transients. Pd nuclei density was calculated as 3.55 × 108 cm−2. Usage of diluted neutral electrolyte enables slower growing of Pd nanowires owing to increase in the electrodeposition potential and thus obtained Pd nanowires have higher crystallinity with lower dislocations. In fact, this high crystallinity of Pd nanowires provides them positive effect for sensor performances especially

Archaeogenetic analysis of Neolithic sheep from Anatolia suggests a complex demographic history since domestication

Sheep were among the first domesticated animals, but their demographic history is little understood. Here we analyzed nuclear polymorphism and mitochondrial data (mtDNA) from ancient central and west Anatolian sheep dating from Epipaleolithic to late Neolithic, comparatively with modern-day breeds and central Asian Neolithic/Bronze Age sheep (OBI). Analyzing ancient nuclear data, we found that Anatolian Neolithic sheep (ANS) are genetically closest to present-day European breeds relative to Asian breeds, a conclusion supported by mtDNA haplogroup frequencies. In contrast, OBI showed higher genetic affinity to present-day Asian breeds. These results suggest that the east-west genetic structure observed in present-day breeds had already emerged by 6000 BCE, hinting at multiple sheep domestication episodes or early wild introgression in southwest Asia. Furthermore, we found that ANS are genetically distinct from all modern breeds. Our results suggest that European and Anatolian domestic sheep gene pools have been strongly remolded since the Neolithic

The Beaker phenomenon and the genomic transformation of northwest Europe

From around 2750 to 2500 bc, Bell Beaker pottery became widespread across western and central Europe, before it disappeared between 2200 and 1800 bc. The forces that propelled its expansion are a matter of long-standing debate, and there is support for both cultural diffusion and migration having a role in this process. Here we present genome-wide data from 400 Neolithic, Copper Age and Bronze Age Europeans, including 226 individuals associated with Beaker-complex artefacts. We detected limited genetic affinity between Beaker-complex-associated individuals from Iberia and central Europe, and thus exclude migration as an important mechanism of spread between these two regions. However, migration had a key role in the further dissemination of the Beaker complex. We document this phenomenon most clearly in Britain, where the spread of the Beaker complex introduced high levels of steppe-related ancestry and was associated with the replacement of approximately 90% of Britain’s gene pool within a few hundred years, continuing the east-to-west expansion that had brought steppe-related ancestry into central and northern Europe over the previous centuries

Using Salivary Nitrite and Nitrate Levels as a Biomarker for Drug-Induced Gingival Overgrowth

Aim: Drug-induced gingival overgrowth has a multifactorial nature and the pathogenesis is still uncertain. It has been suggested that Nitric Oxide (NO) might play a role in the pathogenesis of drug induced gingival overgrowth due to the contribution of NO to immune response and matrix degradation. NO levels in biological fluids have been used as a diagnostic biomarker in many diseases. The aim of this study is to determine whether NO levels in plasma, saliva, and gingival crevicular fluid (GCF) can serve as a potential biomarker for the evaluation of drug induced gingival overgrowth risk. Materials and Methods: A total of 104 patients, receiving cyclosporine A (p = 35), phenytoin (n = 25), nifedipine (n = 26), or diltiazem (n = 18) participated in the study. The amount of gingival overgrowth was evaluated with two indices and was given as percentage. Periodontal clinical parameters including plaque index (PI), gingival index (GI), gingival bleeding time index (GBTI), and probing depth (PD) were also assessed. Saliva, GCF, and plasma samples were obtained from each participants. Nitrite and nitrate levels in saliva, GCF, and plasma were analyzed by Griess reagent. Results: Salivary nitrite and nitrate levels in responders were significantly higher than those in non responders in only phenytoin group (p 0.05). Nitrite and nitrate levels of gingival crevicular fluid and plasma did not significantly differ between responders and non-responders in all study groups (p > 0.05). Salivary nitrite levels exhibited a significant correlation with PD, GBTI, severity of gingival overgrowth (%G0), and GCF volume (p 0.05). Conclusion: Salivary nitrite and nitrate levels could be used as periodontal disease biomarkers in phenytoin induced gingival overgrowth, and that saliva seems to have a better diagnostic potential than GCF and plasma for the evaluation of drug-induced gingival overgrowth risk. However, when all drug groups were considered, saliva nitrite and nitrate levels could not be used as a biomarker for drug induced gingival overgrowth

Saddle Points and Accelerated Perceptron Algorithms

Abstract In this paper, we consider the problem of finding a linear (binary) classifier or providing a nearinfeasibility certificate if there is none. We bring a new perspective to addressing these two problems simultaneously in a single efficient process, by investigating a related Bilinear Saddle Point Problem (BSPP). More specifically, we show that a BSPP-based approach provides either a linear classifier or an -infeasibility certificate. We show that the accelerated primal-dual algorithm, Mirror Prox, can be used for this purpose and achieves the best known convergence rate of O( , which is almost independent of the problem size, n. Our framework also solves kernelized and conic versions of the problem, with the same rate of convergence. We support our theoretical findings with an empirical study on synthetic and real data, highlighting the efficiency and numerical stability of our algorithm, especially on large-scale instances