Sex-related differences in aging rate are associated with sex chromosome system in amphibians

Sex-related differences in mortality are widespread in the animal kingdom. Although studies have shown that sex determination systems might drive lifespan evolution, sex chromosome influence on aging rates have not been investigated so far, likely due to an apparent lack of demographic data from clades including both XY (with heterogametic males) and ZW (heterogametic females) systems. Taking advantage of a unique collection of capture-recapture datasets in amphibians, a vertebrate group where XY and ZW systems have repeatedly evolved over the past 200 million years, we examined whether sex heterogamy can predict sex differences in aging rates and lifespans. We showed that the strength and direction of sex differences in aging rates (and not lifespan) differ between XY and ZW systems. Sex-specific variation in aging rates was moderate within each system, but aging rates tended to be consistently higher in the heterogametic sex. This led to small but detectable effects of sex chromosome system on sex differences in aging rates in our models. Although preliminary, our results suggest that exposed recessive deleterious mutations on the X/Z chromosome (the "unguarded X/Z effect") or repeat-rich Y/W chromosome (the "toxic Y/W effect") could accelerate aging in the heterogametic sex in some vertebrate clades.Peer reviewe

20th Century Retreat and Recent Drought Accelerated Extinction of Mountain Glaciers and Perennial Snowfields in the Trinity Alps, California

The Trinity Alps is a compact glaciated subrange of the Klamath Mountains in northwest California with elevations \u3c 2,750 m making it a unique location in the western US to study glacier change. We examined glacier change since the last Little Ice Age advance in the late 19th century by mapping historic glacier areas using clearly defined moraines. At least six glaciers existed in the Trinity Alps around the 1880s and estimated glacier cover was at least 55.4 ha (0.554 km2). We tracked changes in two glaciers and two perennial snowfields since that time. Total glacier area decreased by 79% (43.8 ha to 9.1 ha) from the 1880s to 1994. By 2013, glacier area decreased another 7% of the 1880s area to 6.0 ha. Overall, retreat was similar for Salmon Glacier (–89%) and Grizzly Glacier (–84%), but since 1994 Salmon retreat has been much faster, 53% versus 16% for Grizzly. The extended 2012 to 2016 drought resulted in catastrophic retreat of both glaciers such that by 2015 Salmon Glacier disappeared and Grizzly Glacier retreated to 1.67 ha and partially stagnated, a –97% loss of total glacier area since the 1880s. Two snowfields (3.02 ha total area in 1955) were tracked since 1955, the Mirror Lake snowfield disappeared by the summer of 2013 and the Canyon Creek snowfield disappeared by October 2014. The unusually warm summer temperatures since 2005 combined with extremely low winter precipitation from 2013 to 2015 caused rapid retreat and near elimination of the Trinity Alps perennial snow and ice threatening local biodiversity that depends on these features

Sex‐related differences in aging rate are associated with sex chromosome system in amphibians

Sex-related differences in mortality are widespread in the animal kingdom. Although studies have shown that sex determination systems might drive lifespan evolution, sex chromosome influence on aging rates have not been investigated so far, likely due to an apparent lack of demographic data from clades including both XY (with heterogametic males) and ZW (heterogametic females) systems. Taking advantage of a unique collection of capture–recapture datasets in amphibians, a vertebrate group where XY and ZW systems have repeatedly evolved over the past 200 million years, we examined whether sex heterogamy can predict sex differences in aging rates and lifespans. We showed that the strength and direction of sex differences in aging rates (and not lifespan) differ between XY and ZW systems. Sex-specific variation in aging rates was moderate within each system, but aging rates tended to be consistently higher in the heterogametic sex. This led to small but detectable effects of sex chromosome system on sex differences in aging rates in our models. Although preliminary, our results suggest that exposed recessive deleterious mutations on the X/Z chromosome (the “unguarded X/Z effect”) or repeat-rich Y/W chromosome (the “toxic Y/W effect”) could accelerate aging in the heterogametic sex in some vertebrate clades

Diverse aging rates in ectothermic tetrapods provide insights for the evolution of aging and longevity

Comparative studies of mortality in the wild are necessary to understand the evolution of aging; yet, ectothermic tetrapods are underrepresented in this comparative landscape, despite their suitability for testing evolutionary hypotheses. We present a study of aging rates and longevity across wild tetrapod ectotherms, using data from 107 populations (77 species) of nonavian reptiles and amphibians. We test hypotheses of how thermoregulatory mode, environmental temperature, protective phenotypes, and pace of life history contribute to demographic aging. Controlling for phylogeny and body size, ectotherms display a higher diversity of aging rates compared with endotherms and include phylogenetically widespread evidence of negligible aging. Protective phenotypes and life-history strategies further explain macroevolutionary patterns of aging. Analyzing ectothermic tetrapods in a comparative context enhances our understanding of the evolution of aging