Novel pyrrolizidine alkaloid

The present invention involves a purified bioactive compound of the formula: ##STR1## wherein at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are H or an acyl having less than about five carbon atoms. More specifically the preferred purified bioactive compound is (1R, 1R, 3R, 7S, 7aR)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine.Board of Regents, University of Texas Syste

Sinusoidal-gust generation with a pitching and plunging airfoil

The generation of uniform, periodic gust disturbances in an experimental context is demonstrated using a single oscillating airfoil. A pitching and heaving symmetric airfoil is suggested as a simpler alternative to existing gust-generation methods. The Theodorsen theory of unsteady aerodynamics is used as an analytical tool to dictate the kinematics necessary to produce well-defined sinusoidal gusts downstream of the airfoil. These analytic predictions improve the symmetry of fluctuations in the vertical velocity induced by the airfoil, as well as minimize the influence of vorticity shed by the oscillating airfoil. The apparatus is shown to produce smooth, repeatable gusts with high amplitudes and reduced frequencies compared to other gust-generation mechanisms in the literature. Furthermore, the control of downstream flow properties by airfoil motion kinematics has applications in experimental aerodynamics, the design of rotorcraft and light aerial vehicles, and biological propulsion.Comment: Under revie

Conversa amb Francesco Casetti

Entrevista a Francesco Casetti, especialista en semiòtica del cinema i la televisió, feta a Barcelona el 3 de juliol de 200

Inherent-Structure Dynamics and Diffusion in Liquids

The self-diffusion constant D is expressed in terms of transitions among the local minima of the potential (inherent structure, IS) and their correlations. The formulae are evaluated and tested against simulation in the supercooled, unit-density Lennard-Jones liquid. The approximation of uncorrelated IS-transition (IST) vectors, D_{0}, greatly exceeds D in the upper temperature range, but merges with simulation at reduced T ~ 0.50. Since uncorrelated IST are associated with a hopping mechanism, the condition D ~ D_{0} provides a new way to identify the crossover to hopping. The results suggest that theories of diffusion in deeply supercooled liquids may be based on weakly correlated IST.Comment: submitted to PR

Social Media Is Permanent, You Are Not: Evaluating The Digital Property Dilemma In Florida Probate

The digital after life1 has quickly become the brave new world of probate law and estate planning.2 The reason for this is because as recently as 2010, reports show that “[seventy-seven percent] of Americans use e-mail or the [I]nternet, at least occasionally

A new species of \u3cem\u3eEuscorpius\u3c/em\u3e Thorell, 1876 from the western Balkans (Scorpiones: Euscorpiidae)

A new scorpion species, Euscorpius feti sp. n., is described from the western Balkans based on morphological evidence. It is characterized by long-limbed overall appearance, medium-large size, light brown to reddish color, and a high trichobothrial count (Pv = 11–12, et = 8, em = 4 and eb = 4)

Reconsideration of the taxonomy of \u3cem\u3eEuscorpius tergestinus\u3c/em\u3e (Scorpiones: Euscorpiidae)

After the revision of Fet & Soleglad (2002), Euscorpius tergestinus (C. L. Koch, 1837) was considered a polymorphic species widespread from France to Croatia. In this study, we reconsidered the taxonomy of E. tergestinus s.str. based on morphological and genetic evidence, its range, and its original description. Euscorpius aquilejensis (C. L. Koch, 1837), stat. nov., previously synonymous with E. tergestinus, is elevated to species status herein. A preliminary phylogenetic analysis based on available GenBank 16S rDNA data shows a separate, basal position of E. aquilejensis and some other Euscorpius species, which implies that the subgenus Euscorpius s.str. is paraphyletic

Fierce Compassion and Reflexivity: Transforming Practice at the University of Melbourne Archives

In 2016, the University of Melbourne Archives (UMA) commenced a program of change with regard to its records about child welfare in Victoria. This was driven by a social justice imperative to repair past harms done to Care Leavers (people who grew up in orphanages, children's homes, or foster care) while in out-of-home care, and for whom records play an integral role. UMA worked with Care Leavers, advocacy groups and support services to review their policies, procedures and practices around archival documentation and access arrangements. In this article, the authors explore those efforts through the prism of radical empathy (or rather a compassionate response to empathy) and analyze what was achieved and the challenges that remain.  Pre-print first published online 10/22/202