158 research outputs found
Geometric Entanglement of Symmetric States and the Majorana Representation
Permutation-symmetric quantum states appear in a variety of physical
situations, and they have been proposed for quantum information tasks. This
article builds upon the results of [New J. Phys. 12, 073025 (2010)], where the
maximally entangled symmetric states of up to twelve qubits were explored, and
their amount of geometric entanglement determined by numeric and analytic
means. For this the Majorana representation, a generalization of the Bloch
sphere representation, can be employed to represent symmetric n qubit states by
n points on the surface of a unit sphere. Symmetries of this point distribution
simplify the determination of the entanglement, and enable the study of quantum
states in novel ways. Here it is shown that the duality relationship of
Platonic solids has a counterpart in the Majorana representation, and that in
general maximally entangled symmetric states neither correspond to anticoherent
spin states nor to spherical designs. The usability of symmetric states as
resources for measurement-based quantum computing is also discussed.Comment: 10 pages, 8 figures; submitted to Lecture Notes in Computer Science
(LNCS
Intersex, infertility and the future: early diagnoses and the imagined life course
This is the author accepted manuscript. The final version is available from Wiley via the DOI in this recordInfertility is often recognised as a status that is medically identified in adulthood after unsuccessful
attempts to conceive. This paper develops existing literature by illustrating how current
conceptualisations of infertility do not incorporate a full range of experiences. Drawing on detailed,
reflective diaries and in-depth interviews with five participants, I explore how infertility is experienced
and understood by women with variations of sex characteristics (VSCs) or intersex traits. I argue that
greater consideration needs to be applied to intersex people and the circumstances of an infertility
status that may be received in infancy, childhood or adolescence, before or outside of attempts to
conceive, and without undergoing fertility treatment.
Through discussions of time and futurity, this paper seeks to explore how visions of the future
coalesce with an infertile status that is received in combination with an atypical sex status early in life.
The paper indicates that early infertility can hinder some intersex children and young people’s
ambitions. However, infertility is not understood to be pathological or consistently prohibitive
throughout the lives of everyone affected. Intersex women's conceptions of a potentially childless
future are varied, complex, ambivalent, and in some cases transitional throughout the life courseEconomic and Social Research Council (ESRC
Measurement of (anti)deuteron and (anti)proton production in DIS at HERA
The first observation of (anti)deuterons in deep inelastic scattering at HERA
has been made with the ZEUS detector at a centre-of-mass energy of 300--318 GeV
using an integrated luminosity of 120 pb-1. The measurement was performed in
the central rapidity region for transverse momentum per unit of mass in the
range 0.3<p_T/M<0.7. The particle rates have been extracted and interpreted in
terms of the coalescence model. The (anti)deuteron production yield is smaller
than the (anti)proton yield by approximately three orders of magnitude,
consistent with the world measurements.Comment: 26 pages, 9 figures, 5 tables, submitted to Nucl. Phys.
Forward jet production in deep inelastic ep scattering and low-x parton dynamics at HERA
Differential inclusive jet cross sections in neutral current deep inelastic
ep scattering have been measured with the ZEUS detector. Three phase-space
regions have been selected in order to study parton dynamics where the effects
of BFKL evolution might be present. The measurements have been compared to the
predictions of leading-logarithm parton shower Monte Carlo models and
fixed-order perturbative QCD calculations. In the forward region, QCD
calculations at order alpha_s^1 underestimate the data up to an order of
magnitude at low x. An improved description of the data in this region is
obtained by including QCD corrections at order alpha_s^2, which account for the
lowest-order t-channel gluon-exchange diagrams, highlighting the importance of
such terms in parton dynamics at low x.Comment: 25 pages, 4 figure
SJS/TEN 2019: From Science to Translation
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are potentially life-threatening, immune-mediated adverse reactions characterized by widespread erythema, epidermal necrosis, and detachment of skin and mucosa. Efforts to grow and develop functional international collaborations and a multidisciplinary interactive network focusing on SJS/TEN as an uncommon but high burden disease will be necessary to improve efforts in prevention, early diagnosis and improved acute and long-term management. SJS/TEN 2019: From Science to Translation was a 1.5-day scientific program held April 26-27, 2019, in Vancouver, Canada. The meeting successfully engaged clinicians, researchers, and patients and conducted many productive discussions on research and patient care needs
Pion contamination in the MICE muon beam
The international Muon Ionization Cooling Experiment (MICE) will perform a systematic investigation of ionization cooling with muon beams of momentum between 140 and 240\,MeV/c at the Rutherford Appleton Laboratory ISIS facility. The measurement of ionization cooling in MICE relies on the selection of a pure sample of muons that traverse the experiment. To make this selection, the MICE Muon Beam is designed to deliver a beam of muons with less than 1\% contamination. To make the final muon selection, MICE employs a particle-identification (PID) system upstream and downstream of the cooling cell. The PID system includes time-of-flight hodoscopes, threshold-Cherenkov counters and calorimetry. The upper limit for the pion contamination measured in this paper is at 90\% C.L., including systematic uncertainties. Therefore, the MICE Muon Beam is able to meet the stringent pion-contamination requirements of the study of ionization cooling.Department of Energy and National Science Foundation (U.S.A.), the Instituto Nazionale di Fisica Nucleare (Italy), the Science and Technology Facilities Council (U.K.), the European Community under the European Commission Framework Programme 7 (AIDA project, grant agreement no. 262025, TIARA project, grant agreement no. 261905, and EuCARD), the Japan Society for the Promotion of Science and the Swiss National Science Foundation, in the framework of the SCOPES programme
Measurement of dijet photoproduction for events with a leading neutron at HERA
Differential cross sections for dijet photoproduction and this process in
association with a leading neutron, e+ + p -> e+ + jet + jet + X (+ n), have
been measured with the ZEUS detector at HERA using an integrated luminosity of
40 pb-1. The fraction of dijet events with a leading neutron was studied as a
function of different jet and event variables. Single- and double-differential
cross sections are presented as a function of the longitudinal fraction of the
proton momentum carried by the leading neutron, xL, and of its transverse
momentum squared, pT^2. The dijet data are compared to inclusive DIS and
photoproduction results; they are all consistent with a simple pion-exchange
model. The neutron yield as a function of xL was found to depend only on the
fraction of the proton beam energy going into the forward region, independent
of the hard process. No firm conclusion can be drawn on the presence of
rescattering effects.Comment: 40 pages, 18 figure
Deep inelastic inclusive and diffractive scattering at values from 25 to 320 GeV with the ZEUS forward plug calorimeter
Deep inelastic scattering and its diffractive component, , have been studied at HERA with the ZEUS
detector using an integrated luminosity of 52.4 pb. The method has
been used to extract the diffractive contribution. A wide range in the
centre-of-mass energy (37 -- 245 GeV), photon virtuality (20 -- 450
GeV) and mass (0.28 -- 35 GeV) is covered. The diffractive cross
section for GeV rises strongly with , the rise becoming
steeper as increases. The data are also presented in terms of the
diffractive structure function, , of the proton. For fixed
and fixed , \xpom F^{\rm D(3)}_2 shows a strong rise as \xpom \to
0, where \xpom is the fraction of the proton momentum carried by the
Pomeron. For Bjorken-, \xpom F^{\rm D(3)}_2 shows
positive scaling violations, while for
negative scaling violations are observed. The diffractive structure function is
compatible with being leading twist. The data show that Regge factorisation is
broken.Comment: 89 pages, 27 figure
Whole-genome sequencing reveals host factors underlying critical COVID-19
Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
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