105 research outputs found
The Mid-Infrared Fundamental Plane of Early-Type Galaxies
Three observables of early-type galaxies - size (), surface brightness
(), and velocity dispersion () - form a tight planar
correlation known as the fundamental plane (FP), which has provided great
insights into the galaxy formation and the evolution processes. However, the FP
has been found to be tilted against the simple virial expectation, prompting
debates on its origin. In order to investigate the contribution of systematic
stellar population variation to the FP tilt, we study here the FP relations of
early-type galaxies in mid-infrared (MIR) which may represent the stellar mass
well. We examined the wavelength dependence of the FP coefficients, and
in , using a sample of 56
early-type galaxies for which visible (V-band), near-infrared (K-band), and MIR
(Spitzer IRAC, 3.6--8.0m) data are available. We find that the coefficient
increases as a function of wavelength as , while the coefficient reaches the closest to -1 at 3.6--5.8m.
When applied to the visible FP coefficients derived from a larger sample of
nearby early-type galaxies, we get the FP relation with (1.6--1.8,-0.9) at 3.6m. Our result suggests that the stellar population
effect can explain more than half of the FP tilt, closing the gap between the
virial expectation and the optical FP. The reduction in the FP tilt is
reflected in the dynamical mass-to-light ratio, , dependence on
which decreases toward 3.6--5.8m, suggesting that the MIR light better
represents mass than the shorter wavelengths.Comment: 5 pages, 3 figures, to appear in ApJ
The Host Galaxy and Optical Light Curve of the Gamma-Ray Burst GRB 980703
We present deep HST/STIS and ground-based photometry of the host galaxy of
the gamma-ray burst GRB 980703 taken 17, 551, 710, and 716 days after the
burst. We find that the host is a blue, slightly over-luminous galaxy with
V_gal = 23.00 +/- 0.10, (V-R)_gal = 0.43 +/- 0.13, and a centre that is
approximately 0.2 mag bluer than the outer regions of the galaxy. The galaxy
has a star-formation rate of 8-13 M_sun/yr, assuming no extinction in the host.
We find that the galaxy is best fit by a Sersic R^(1/n) profile with n ~= 1.0
and a half-light radius of 0.13 arcsec (= 0.72/h_100 proper kpc). This
corresponds to an exponential disk with a scale radius of 0.22 arcsec (=
1.21/h_100 proper kpc). Subtracting a fit with elliptical isophotes leaves
large residuals, which suggests that the host galaxy has a somewhat irregular
morphology, but we are unable to connect the location of GRB 980703 with any
special features in the host. The host galaxy appears to be a typical example
of a compact star forming galaxy similar to those found in the Hubble Deep
Field North. The R-band light curve of the optical afterglow associated with
this gamma-ray burst is consistent with a single power-law decay having a slope
of alpha = -1.37 +/- 0.14. Due to the bright underlying host galaxy the late
time properties of the light-curve are very poorly constrained. The decay of
the optical light curve is consistent with a contribution from an underlying
Type Ic supernova like SN1998bw, or a dust echo, but such contributions cannot
be securely established.Comment: 9 pages, 5 figures, LaTeX using A&A Document Class v4.05, to appear
in A&
The Escherichia coli transcriptome mostly consists of independently regulated modules
Underlying cellular responses is a transcriptional regulatory network (TRN) that modulates gene expression. A useful description of the TRN would decompose the transcriptome into targeted effects of individual transcriptional regulators. Here, we apply unsupervised machine learning to a diverse compendium of over 250 high-quality Escherichia coli RNA-seq datasets to identify 92 statistically independent signals that modulate the expression of specific gene sets. We show that 61 of these transcriptomic signals represent the effects of currently characterized transcriptional regulators. Condition-specific activation of signals is validated by exposure of E. coli to new environmental conditions. The resulting decomposition of the transcriptome provides: a mechanistic, systems-level, network-based explanation of responses to environmental and genetic perturbations; a guide to gene and regulator function discovery; and a basis for characterizing transcriptomic differences in multiple strains. Taken together, our results show that signal summation describes the composition of a model prokaryotic transcriptome
The DEEP2 Galaxy Redshift Survey: Design, Observations, Data Reduction, and Redshifts
We describe the design and data sample from the DEEP2 Galaxy Redshift Survey,
the densest and largest precision-redshift survey of galaxies at z ~ 1
completed to date. The survey has conducted a comprehensive census of massive
galaxies, their properties, environments, and large-scale structure down to
absolute magnitude M_B = -20 at z ~ 1 via ~90 nights of observation on the
DEIMOS spectrograph at Keck Observatory. DEEP2 covers an area of 2.8 deg^2
divided into four separate fields, observed to a limiting apparent magnitude of
R_AB=24.1. Objects with z < 0.7 are rejected based on BRI photometry in three
of the four DEEP2 fields, allowing galaxies with z > 0.7 to be targeted ~2.5
times more efficiently than in a purely magnitude-limited sample. Approximately
sixty percent of eligible targets are chosen for spectroscopy, yielding nearly
53,000 spectra and more than 38,000 reliable redshift measurements. Most of the
targets which fail to yield secure redshifts are blue objects that lie beyond z
~ 1.45. The DEIMOS 1200-line/mm grating used for the survey delivers high
spectral resolution (R~6000), accurate and secure redshifts, and unique
internal kinematic information. Extensive ancillary data are available in the
DEEP2 fields, particularly in the Extended Groth Strip, which has evolved into
one of the richest multiwavelength regions on the sky. DEEP2 surpasses other
deep precision-redshift surveys at z ~ 1 in terms of galaxy numbers, redshift
accuracy, sample number density, and amount of spectral information. We also
provide an overview of the scientific highlights of the DEEP2 survey thus far.
This paper is intended as a handbook for users of the DEEP2 Data Release 4,
which includes all DEEP2 spectra and redshifts, as well as for the
publicly-available DEEP2 DEIMOS data reduction pipelines. [Abridged]Comment: submitted to ApJS; data products available for download at
http://deep.berkeley.edu/DR4
Factors related to severe dengue during an epidemic in Vitoria, State of Espirito Santo, Brazil, 2011
On the buildup of massive early-type galaxies at z<~1. I- Reconciling their hierarchical assembly with mass-downsizing
Several studies have tried to ascertain whether or not the increase in
abundance of the early-type galaxies (E-S0a's) with time is mainly due to major
mergers, reaching opposite conclusions. We have tested it directly through
semi-analytical modelling, by studying how the massive early-type galaxies with
log(M_*/Msun)>11 at z~0 (mETGs) would have evolved backwards-in-time, under the
hypothesis that each major merger gives place to an early-type galaxy. The
study was carried out just considering the major mergers strictly reported by
observations at each redshift, and assuming that gas-rich major mergers
experience transitory phases of dust-reddened, star-forming galaxies (DSFs).
The model is able to reproduce the observed evolution of the galaxy LFs at
z<~1, simultaneously for different rest-frame bands (B, I, and K) and for
different selection criteria on color and morphology. It also provides a
framework in which apparently-contradictory results on the recent evolution of
the luminosity function (LF) of massive, red galaxies can be reconciled, just
considering that observational samples of red galaxies can be significantly
contaminated by DSFs. The model proves that it is feasible to build up ~50-60%
of the present-day mETG population at z<~1 and to reproduce the observational
excess by a factor of ~4-5 of late-type galaxies at 0.8<z<1 through the
coordinated action of wet, mixed, and dry major mergers, fulfilling global
trends that are in general agreement with mass-downsizing. The bulk of this
assembly takes place during ~1 Gyr elapsed at 0.8<z<1. The model suggests that
major mergers have been the main driver for the observational migration of mass
from the massive-end of the blue galaxy cloud to that of the red sequence in
the last ~8 Gyr.(Abridged)Comment: Accepted for publication in Astronomy & Astrophysics; 21 pages, 8
figures. Minor corrections included, shortened title. Results and conclusions
unchange
Foxa1 Reduces Lipid Accumulation in Human Hepatocytes and Is Down-Regulated in Nonalcoholic Fatty Liver
Triglyceride accumulation in nonalcoholic fatty liver (NAFL) results from unbalanced lipid metabolism which, in the liver, is controlled by several transcription factors. The Foxa subfamily of winged helix/forkhead box (Fox) transcription factors comprises three members which play important roles in controlling both metabolism and homeostasis through the regulation of multiple target genes in the liver, pancreas and adipose tissue. In the mouse liver, Foxa2 is repressed by insulin and mediates fasting responses. Unlike Foxa2 however, the role of Foxa1 in the liver has not yet been investigated in detail. In this study, we evaluate the role of Foxa1 in two human liver cell models, primary cultured hepatocytes and HepG2 cells, by adenoviral infection. Moreover, human and rat livers were analyzed to determine Foxa1 regulation in NAFL. Results demonstrate that Foxa1 is a potent inhibitor of hepatic triglyceride synthesis, accumulation and secretion by repressing the expression of multiple target genes of these pathways (e.g., GPAM, DGAT2, MTP, APOB). Moreover, Foxa1 represses the fatty acid transporter protein FATP2 and lowers fatty acid uptake. Foxa1 also increases the breakdown of fatty acids by inducing peroxisomal fatty acid β-oxidation and ketone body synthesis. Finally, Foxa1 is able to largely up-regulate UCP1, thereby dissipating energy and consistently decreasing the mitochondria membrane potential. We also report that human and rat NAFL have a reduced Foxa1 expression, possibly through a protein kinase C-dependent pathway. We conclude that Foxa1 is an antisteatotic factor that coordinately tunes several lipid metabolic pathways to block triglyceride accumulation in hepatocytes. However, Foxa1 is down-regulated in human and rat NAFL and, therefore, increasing Foxa1 levels could protect from steatosis. Altogether, we suggest that Foxa1 could be a novel therapeutic target for NAFL disease and insulin resistance
Dynamic thoracohumeral kinematics are dependent upon the etiology of the shoulder injury
[EN] Obtaining kinematic patterns that depend on the shoulder injury may be important when planning rehabilitation. The main goal of this study is to explore whether the kinematic patterns of continuous and repetitive shoulder elevation motions are different according to the type of shoulder injury in question, specifically tendinopathy or rotator cuff tear, and to analyze the influence of the load handled during its assessment. For this purpose, 19 individuals with tendinopathy and 9 with rotator cuff tear performed a repetitive scaption movement that was assessed with stereophotogrammetry. Furthermore, static range of motion (ROM) and isometric strength were evaluated with a goniometer and a dynamometer, respectively. Dynamic measurements of maximum elevation (Emax), variablility of the maximum angle (VMA), maximum angular velocity (Velmax), and time to maximum velocity (tmaxvel) were found to be significantly different between the tendinopathy group (TG) and the rotator cuff tear group (RTCG). No differences were found in the ROM assessed with goniometry and the isometric strength. The effect of increasing the load placed in the hand during the scaption movement led to significant differences in Emax, VMA, tmaxvel and repeatability. Therefore, only the dynamic variables showed sufficient capability of detecting differences in functional performance associated with structural shoulder injury. The differences observed in the kinematic variables between patients with tendinopathy and rotator cuff tear seem to be related to alterations in thoracohumeral rhythm and neuromuscular control. Kinematic analysis may contribute to a better understanding of the functional impact of shoulder injuries, which would help in the assessment and treatment of shoulder pain.This work was funded by the Spanish Government, Secretaria de Estado de Investigacion, Desarrollo e Innovacion, and co-financed by EU FEDER funds (Grant DPI2013-44227-R). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Lopez Pascual, J.; Page Del Pozo, AF.; Serra Añó, P. (2017). Dynamic thoracohumeral kinematics are dependent upon the etiology of the shoulder injury. PLoS ONE. 12(8). https://doi.org/10.1371/journal.pone.0183954S12
The metallicities of luminous, massive field galaxies at intermediate redshifts
We derive oxygen abundances for a sample of 40 luminous (M_{B} < -19),
star-forming, mostly disk, field galaxies with redshifts in the range 0.2 < z <
0.8(12+log(O/H))~8.6$,
than local galaxies with similar luminosities. Interestingly, these luminous,
massive, intermediate redshift, star-forming galaxies with low oxygen
abundances exhibit physical conditions, i.e., emission line equivalent width
and ionization state, very similar to those of local faint and metal-poor
star-forming galaxies. The oxygen abundance of the interstellar gas does not
seem to correlate with the maximum rotation velocity or the emission scale
length of the parent galaxy. This suggests that there is a diversity in the
intrinsic properties of the massive field galaxy population at intermediate
redshifts (ABRIDGED).Comment: 19 pages, 14 figures, MNRAS in pres
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