4,758 research outputs found
The Influence of Interference on the Kondo Effect in a Quantum Dot
We study the Kondo effect in a model system of a quantum dot embedded in an
Aharanov-Bohm ring connected to two leads. By transforming to the scattering
basis of the direct inter-lead tunneling, we are able to describe precisely how
the Kondo screening of the dot spin occurs. We calculate the Kondo temperature
and zero-temperature conductance and find that both are influenced by the
Aharanov-Bohm ring as well as the electron density in the leads. We also
calculate the form of an additional potential scattering term that arises at
low energies due to the breaking of particle-hole symmetry. Many of our results
are supported by numerical analysis using the numerical renormalization group.Comment: 24 pages, 18 figure
Molecular self-organization: Predicting the pattern diversity and lowest energy state of competing ordering motifs
Self-organized monolayers of highly flexible \Frechet dendrons were deposited
on graphite surfaces by solution casting. Scanning tunneling microscopy (STM)
reveals an unprecedented variety of patterns with up to seven stable
hierarchical ordering motifs serving as a versatile model system. The essential
molecular properties determined by molecular mechanics simulations are
condensed to a coarse grained interaction site model of various chain
configurations. In a Monte Carlo approach with random starting configurations
the experimental pattern diversity can be reproduced in all facets of the local
and global ordering. Based on an energy analysis of the Monte Carlo and
molecular mechanics modeling the thermodynamically most stable pattern is
predicted coinciding with the pattern, which dominates in the STM images after
several hours or upon moderate heating.Comment: 6 pages, 7 figure
Between male variation in semen characteristics and preliminary results on the dilution of semen in the ostrich
Abstract This study is part of an ongoing project on artificial insemination in ostriches. The physical output of neat semen from four ostrich males was investigated and the effect of reconstituting semen with: 1) seminal plasma of the same male (SPS); 2) seminal plasma of another male (SPD), and 3) Dulbecco's Modified Eagles Medium (DMEM). Semen was collected daily from one or two pairs of males using the dummy female method, each pair being replicated twice. Spermatozoa viability in neat semen, SPS, SPD and DMEM was assessed using nigrosin-eosin staining and the proportions of live normal, live abnormal and dead sperm were determined. Semen volume (mean ± SE) was 1.27 ± 0.13 mL, the concentration of spermatozoa 3.68 ± 0.17 x 10 9 /mL and the number of spermatozoa 4.92 ± 0.64 x 10 9 /ejaculate. Furthermore, the live normal, live abnormal and dead spermatozoa in the neat semen were 61.2 ± 4.5%, 21.2 ± 2.7% and 17.7 ± 4.3% respectively. The ejaculate volume and the number of dead spermatozoa were not affected by collection time. However, the number of live abnormal spermatozoa increased through the day causing a reduction in live normal spermatozoa. Furthermore, re-suspending spermatozoa in DMEM reduced the number of live normal (31.4 ± 4.6%) and live abnormal spermatozoa (11.0 ± 2.7%) and increased the number of dead spermatozoa (57.6 ± 4.4%). In contrast, numbers of live spermatozoa were higher when suspended in seminal plasma and similar in SPS (53.9 ± 4.6%) and SPD (50.7 ± 4.6%). These are the first crucial steps to determining the optimum semen collection time and to improving the viability of diluted spermatozoa
Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome : a systematic review and meta-analysis
Aims/hypothesis
FTO gene single nucleotide polymorphisms (SNPs) have been shown to be associated with obesity-related traits and type 2 diabetes. Several small studies have suggested a greater than expected effect of the FTO rs9939609 SNP on weight in polycystic ovary syndrome (PCOS). We therefore aimed to examine the impact of FTO genotype on BMI and weight in PCOS.
Methods
A systematic search of medical databases (PubMed, EMBASE and Cochrane CENTRAL) was conducted up to the end of April 2011. Seven studies describing eight distinct PCOS cohorts were retrieved; seven were genotyped for SNP rs9939609 and one for SNP rs1421085. The per allele effect on BMI and body weight increase was calculated and subjected to meta-analysis.
Results
A total of 2,548 women with PCOS were included in the study; 762 were TT homozygotes, 1,253 had an AT/CT genotype, and 533 were AA/CC homozygotes. Each additional copy of the effect allele (A/C) increased the BMI by a mean of 0.19 z score units (95% CI 0.13, 0.24; p = 2.26 × 10−11) and body weight by a mean of 0.20 z score units (95% CI 0.14, 0.26; p = 1.02 × 10−10). This translated into an approximately 3.3 kg/m2 increase in BMI and an approximately 9.6 kg gain in body weight between TT and AA/CC homozygotes. The association between FTO genotypes and BMI was stronger in the cohorts with PCOS than in the general female populations from large genome-wide association studies. Deviation from an additive genetic model was observed in heavier populations.
Conclusions/interpretation
The effect of FTO SNPs on obesity-related traits in PCOS seems to be more than two times greater than the effect found in large population-based studies. This suggests an interaction between FTO and the metabolic context or polygenic background of PCOS
Chaos in an Exact Relativistic 3-body Self-Gravitating System
We consider the problem of three body motion for a relativistic
one-dimensional self-gravitating system. After describing the canonical
decomposition of the action, we find an exact expression for the 3-body
Hamiltonian, implicitly determined in terms of the four coordinate and momentum
degrees of freedom in the system. Non-relativistically these degrees of freedom
can be rewritten in terms of a single particle moving in a two-dimensional
hexagonal well. We find the exact relativistic generalization of this
potential, along with its post-Newtonian approximation. We then specialize to
the equal mass case and numerically solve the equations of motion that follow
from the Hamiltonian. Working in hexagonal-well coordinates, we obtaining
orbits in both the hexagonal and 3-body representations of the system, and plot
the Poincare sections as a function of the relativistic energy parameter . We find two broad categories of periodic and quasi-periodic motions that we
refer to as the annulus and pretzel patterns, as well as a set of chaotic
motions that appear in the region of phase-space between these two types.
Despite the high degree of non-linearity in the relativistic system, we find
that the the global structure of its phase space remains qualitatively the same
as its non-relativisitic counterpart for all values of that we could
study. However the relativistic system has a weaker symmetry and so its
Poincare section develops an asymmetric distortion that increases with
increasing . For the post-Newtonian system we find that it experiences a
KAM breakdown for : above which the near integrable regions
degenerate into chaos.Comment: latex, 65 pages, 36 figures, high-resolution figures available upon
reques
The ATLAS SCT grounding and shielding concept and implementation
This paper presents a complete description of Virgo, the French-Italian gravitational wave detector. The detector, built at Cascina, near Pisa (Italy), is a very large Michelson interferometer, with 3 km-long arms. In this paper, following a presentation of the physics requirements, leading to the specifications for the construction of the detector, a detailed description of all its different elements is given. These include civil engineering infrastructures, a huge ultra-high vacuum (UHV) chamber (about 6000 cubic metres), all of the optical components, including high quality mirrors and their seismic isolating suspensions, all of the electronics required to control the interferometer and for signal detection. The expected performances of these different elements are given, leading to an overall sensitivity curve as a function of the incoming gravitational wave frequency. This description represents the detector as built and used in the first data-taking runs. Improvements in different parts have been and continue to be performed, leading to better sensitivities. These will be detailed in a forthcoming paper
Meat quality, skin damage and reproductive performance of ostriches exposed to extensive human presence and interactions at an early age
The effect human presence and interactions performed after hatch to 3 months of age has on ostrich meat quality, skin damage
and reproductive performance at a later age was investigated in 416-day-old ostrich chicks. The chicks were allocated to one of
the three treatments, which varied with regard to exposure to human presence and care for 3 months post-hatch: HP1—extensive
human presence with physical contact (touch, stroking), gentle human voice and visual contact; HP2—extensive human presence
with gentle human voice and visual contact without physical contact; S—standard control treatment, where human presence and
visual contact were limited to routine management, feed and water supply only. Carcass attributes (carcass weight, dressing
percentage and drumstick weight), meat quality traits (pH, colour and tenderness) and skin traits (skin size, skin grading and
number of lesions) were evaluated on twenty-four 1-year-old South African Black (SAB) ostriches
Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC
The uncertainty on the calorimeter energy response to jets of particles is
derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the
calorimeter response to single isolated charged hadrons is measured and
compared to the Monte Carlo simulation using proton-proton collisions at
centre-of-mass energies of sqrt(s) = 900 GeV and 7 TeV collected during 2009
and 2010. Then, using the decay of K_s and Lambda particles, the calorimeter
response to specific types of particles (positively and negatively charged
pions, protons, and anti-protons) is measured and compared to the Monte Carlo
predictions. Finally, the jet energy scale uncertainty is determined by
propagating the response uncertainty for single charged and neutral particles
to jets. The response uncertainty is 2-5% for central isolated hadrons and 1-3%
for the final calorimeter jet energy scale.Comment: 24 pages plus author list (36 pages total), 23 figures, 1 table,
submitted to European Physical Journal
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