73 research outputs found

    De Kunstenaarsfamiilie Delff

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    Huybert tons Jansz

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    Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli

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    The authors analyze the role transcription plays in regulating bacterial metabolic flux. Of 91 transcriptional regulators studied, 2/3 affect absolute fluxes, but only a small number of regulators control the partitioning of flux between different metabolic pathways

    Cyclic-AMP and bacterial cyclic-AMP receptor proteins revisited: adaptation for different ecological niches.

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    Escherichia coli cyclic-AMP receptor protein (CRP) represents one of the paradigms of bacterial gene regulation. Yet despite decades of intensive study, new information continues to emerge that prompts reassessment of this classic regulatory system. Moreover, in recent years CRPs from several other bacterial species have been characterized, allowing the general applicability of the CRP paradigm to be tested. Here the properties of the E. coli, Mycobacterium tuberculosis and Pseudomonas putida CRPs are considered in the context of the ecological niches occupied by these bacteria. It appears that the cyclic-AMP-CRP regulatory system has been adapted to respond to distinct external and internal inputs across a broad sensitivity range that is, at least in part, determined by bacterial lifestyles

    On-Chip Integration of Functional Hybrid Materials and Components in Nanophotonics and Optoelectronics

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    [No abstract available

    Jacob Koninck

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    The LOFAR Magnetism Key Science Project

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    Contains fulltext : 94128.pdf (preprint version ) (Open Access)Magnetic Fields in the Universe: From Laboratory and Stars to Primordial Structures Aug. 21st – 27th 2011, Zakopane, Poland, 21 augustus 201

    Low (linear) teacher effect on student achievement in pre-academic physics education

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    This study investigates the effect of physics education on students' achievement in a large-scale quantitative study of pre-academic high school students throughout the Netherlands. Two aspects of teacher characteristics as perceived by their students are included: their pleasantness principally defined by their perceived friendliness and positive feedback and their centeredness principally defined by the perceived teacher centeredness in the lessons. Furthermore, this study includes four student aspects: their general capability, their quantity of work, their quality of work, and their interest in the lessons. Structural Equation Modeling is used in order to cluster the different variables defining the perceived pleasantness and the perceived centeredness of the teacher and the general capability, interest, and learning attitudes of the students. Furthermore, interrelations among these components and students' achievement are analyzed. Eventually, a very large effect of the students' general capability (6172%) and a remarkably smaller effect of the remaining parameters
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