Maxwell's field coupled nonminimally to quadratic torsion: Induced axion field and birefringence of the vacuum

We consider a possible (parity conserving) interaction between the electromagnetic field $F$ and a torsion field $T^\alpha$ of spacetime. For generic elementary torsion, gauge invariant coupling terms of lowest order fall into two classes that are both nonminimal and {\it quadratic} in torsion. These two classes are displayed explicitly. The first class of the type $\sim F T^2$ yields (undesirable) modifications of the Maxwell equations. The second class of the type $\sim F^2 T^2$ doesn't touch the Maxwell equations but rather modifies the constitutive tensor of spacetime. Such a modification can be completely described in the framework of metricfree electrodynamics. We recognize three physical effects generated by the torsion: (i) An axion field that induces an {\em optical activity} into spacetime, (ii) a modification of the light cone structure that yields {\em birefringence} of the vacuum, and (iii) a torsion dependence of the {\em velocity of light.} We study these effects in the background of a Friedmann universe with torsion. {\it File tor17.tex, 02 August 2003}Comment: 6 page

Familial Occurrence of Multiple Sclerosis with Thyroid Disease and Systemic Lupus Erythematosus

Multiple sclerosis (MS) has some features which suggest it is an autoimmune disease. Autoimmune diseases frequently occur in families, and patients and families often have more than one type of autoimmune disease. However, there are few reports of MS occurring in patients or families with other autoimmune conditions. It is difficult to make a separate diagnosis of MS in a patient who has a systemic autoimmune disease such as systemic lupus erythematosus (SLE) or Sjogren's syndrome, because these diseases can affect the nervous system directly. However, it is possible to make independent diagnoses of MS and an autoimmune disease confined to another single organ in the same patient, or diagnoses of MS and SLE (or other autoimmune diseases) in different family members. Here we describe clinically definite MS in 2 sisters, one of whom had Graves' disease, and the other of whom had a daughter with SLE and with a high titre of anti-thyroid antibodies. Other female family members over 4 generations had histories of thyroid disease, MS and Addison's disease. Available family members were HLA typed. The MS patients were positive for HLA DR2. All but one of the affected family members were related to the proband on the maternal side, and all of these affected females shared an HLA haplotype. However, this haplotype was also present in unaffected individuals. Thus HLA type alone cannot account for the familial occurrence of these disorders. We conclude that, in this family, MS, like autoimmune thyroid disease and SLE, may be an autoimmune disease developing in genetically predisposed individuals

Mirror energy differences in the A=31 mirror nuclei, S31 and P31, and their significance in electromagnetic spin-orbit splitting

Excited states in S31 and P31 were populated in the C12(Ne20,n) and C12(Ne20,p) reactions, respectively, at a beam energy of 32 MeV. High spin states of positive and negative parity have been observed in S31 for the first time, and the yrast scheme of P31 has been extended. Large mirror energy differences between the first 9/2- and 13/2- states were observed, but only small differences for the first 7/2- and 11/2- levels. The significance of these observations is discussed in relation to the electromagnetic spin-orbit effect and the relative binding energy of the levels

Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity

Biosensors with high sensitivity and short time-to-result that are capable of detecting biomarkers in body fluids such as serum are an important prerequisite for early diagnostics in modern healthcare provision. Here, we report the development of an electrochemical impedance-based sensor for the detection in serum of human interleukin-8 (IL-8), a pro-angiogenic chemokine implicated in a wide range of inflammatory diseases. The sensor employs a small and robust synthetic non-antibody capture protein based on a cystatin scaffold that displays high affinity for human IL-8 with a KD of 35 ± 10 nM and excellent ligand specificity. The change in the phase of the electrochemical impedance from the serum baseline, ∆θ(ƒ), measured at 0.1 Hz, was used as the measure for quantifying IL-8 concentration in the fluid. Optimal sensor signal was observed after 15 min incubation, and the sensor exhibited a linear response versus logarithm of IL-8 concentration from 900 fg/ml to 900 ng/ml. A detection limit of around 90 fg/ml, which is significantly lower than the basal clinical levels of 5-10 pg/ml, was observed. Our results are significant for the development of point-of-care and early diagnostics where high sensitivity and short time-to-results are essential

Lifetime measurements of triaxial strongly deformed bands in Tm163

With the Doppler Shift Attenuation Method, quadrupole transition moments Qt were determined for the two recently proposed triaxial strongly deformed (TSD) bands in Tm163. The measured Qt values indicate that the deformation of these bands is larger than that of the yrast signature partners. However, the measured values are smaller than those predicted by theory. This observation appears to be valid for TSD bands in several nuclei of the region

Candidate superdeformed band in 28Si

Recent antisymmetrized molecular dynamics (AMD) calculations for 28Si suggest the presence of a superdeformed (SD) band with a dominant 24Mg+α clustering for its configuration, with firm predictions for its location and associated moment of inertia. This motivates a review of the experimental results reported in the literature with a particular focus on 24Mg(α,γ) studies, as well as on α-like heavy-ion transfer reactions such as 12C(20Ne,α)28Si. Combining this information for the first time leads to a set of candidate SD states whose properties point to their α-cluster structure and strong associated deformation. Analysis of data from Gammasphere allows the electromagnetic decay of these candidate states to be probed and reveals further supporting evidence for such a structure. This paper appraises this body of information and finds the evidence for an SD band is strong

Configurations and decay hindrances of high- K states in Hf 180

Multi-quasiparticle high-K states, several of which are isomeric, were observed in Hf180 with the Gammasphere array. Lifetimes in the ns-μs range were determined using centroid-shift and decay measurements within a μs coincidence time window. The configurations of high-K states involve two and four quasiparticles, with states up to Kπ=(18-) established. High-K excitations are found to be progressively more favored with increasing excitation energy. The K quantum number is quite robust up to the highest spins observed, as evidenced by the large values of the reduced hindrance for isomeric decays. Rotational bands built on three high-K states are identified, and the measured branching ratios in these sequences enable the assignment of underlying configurations. Multi-quasiparticle calculations using the Lipkin-Nogami approach for pairing, with blocking included, reproduce the observed high-K energies quite well

Reevaluation of the P30(p,γ)S31 astrophysical reaction rate from a study of the T=1/2 mirror nuclei, S31 and P31

The P30(p,γ)S31 reaction rate is expected to be the principal determinant for the endpoint of nucleosynthesis in classical novae. To date, the reaction rate has only been estimated through Hauser-Feschbach calculations and is unmeasured experimentally. This paper aims to remedy this situation. Excited states in S31 and P31 were populated in the C12(Ne20,n) and C12(Ne20,p) reactions, respectively, at a beam energy of 32 MeV, and their resulting γdecay was detected with the Gammasphere array. Around half the relevant proton unbound states in S31 corresponding to the Gamow window for the P30(p,γ)S31 reaction were identified. The properties of the unobserved states were inferred from mirror symmetry using our extended data on P31. The implications of this new spectroscopic information for the P30(p,γ)S31 reaction rate are considered and recommendations for future work with radioactive beams are discussed

A First Search for coincident Gravitational Waves and High Energy Neutrinos using LIGO, Virgo and ANTARES data from 2007

We present the results of the first search for gravitational wave bursts associated with high energy neutrinos. Together, these messengers could reveal new, hidden sources that are not observed by conventional photon astronomy, particularly at high energy. Our search uses neutrinos detected by the underwater neutrino telescope ANTARES in its 5 line configuration during the period January - September 2007, which coincided with the fifth and first science runs of LIGO and Virgo, respectively. The LIGO-Virgo data were analysed for candidate gravitational-wave signals coincident in time and direction with the neutrino events. No significant coincident events were observed. We place limits on the density of joint high energy neutrino - gravitational wave emission events in the local universe, and compare them with densities of merger and core-collapse events.Comment: 19 pages, 8 figures, science summary page at http://www.ligo.org/science/Publication-S5LV_ANTARES/index.php. Public access area to figures, tables at https://dcc.ligo.org/cgi-bin/DocDB/ShowDocument?docid=p120000

High-resolution esophageal manometry in pediatrics: Effect of esophageal length on diagnostic measures

BACKGROUND: High-resolution esophageal manometry (HREM), derived esophageal pressure topography metrics (EPT), integrated relaxation pressure (IRP), and distal latency (DL) are influenced by age and size. Combined pressure and intraluminal impedance also allow derivation of metrics that define distension pressure and bolus flow timing. We prospectively investigated the effects of esophageal length on these metrics to determine whether adjustment strategies are required for children. METHODS: Fifty-five children (12.3 ± 4.5 years) referred for HREM, and 30 healthy adult volunteers (46.9 ± 3.8 years) were included. Studies were performed using the MMS system and a standardized protocol including 10 × 5 mL thin liquid bolus swallows (SBM kit, Trisco Foods) and analyzed via Swallow Gateway (www.swallowgateway.com). Esophageal distension pressures and swallow latencies were determined in addition to EGJ resting pressure and standard EPT metrics. Effects of esophageal length were examined using partial correlation, correcting for age. Adult-derived upper limits were adjusted for length using the slopes of the identified linear equations. KEY RESULTS: Mean esophageal length in children was 16.8 ± 2.8 cm and correlated significantly with age (r = 0.787, P = .000). Shorter length correlated with higher EGJ resting pressure and 4-s integrated relaxation pressures (IRP), distension pressures, and shorter contraction latencies. Ten patients had an IRP above the adult upper limit. Adjustment for esophageal length reduced the number of patients with elevated IRP to three. CONCLUSIONS & INFERENCES: We prospectively confirmed that certain EPT metrics, as well as potential useful adjunct pressure-impedance measures such as distension pressure, are substantially influenced by esophageal length and require adjusted diagnostic thresholds specifically for children.Maartje M. J. Singendonk, Lara F. Ferris, Lisa McCall, Grace Seiboth, Katie Lowe, David Moore, Paul Hammond, Richard Couper, Rammy Abu, Assi, Charles Cock, Marc A. Benninga, Michiel P. van Wijk, Taher I. Omar