Constructing the secular architecture of the solar system I: The giant planets

Using numerical simulations, we show that smooth migration of the giant planets through a planetesimal disk leads to an orbital architecture that is inconsistent with the current one: the resulting eccentricities and inclinations of their orbits are too small. The crossing of mutual mean motion resonances by the planets would excite their orbital eccentricities but not their orbital inclinations. Moreover, the amplitudes of the eigenmodes characterising the current secular evolution of the eccentricities of Jupiter and Saturn would not be reproduced correctly; only one eigenmode is excited by resonance-crossing. We show that, at the very least, encounters between Saturn and one of the ice giants (Uranus or Neptune) need to have occurred, in order to reproduce the current secular properties of the giant planets, in particular the amplitude of the two strongest eigenmodes in the eccentricities of Jupiter and Saturn.Comment: Astronomy & Astrophysics (2009) in pres

MIGRATE: mobile device virtualisation through state transfer

Delegation of processing tasks to the network has moved from cloud-based schemes to edge computing solutions where nearby servers process requests in a timely manner. Virtualisation technologies have recently given data cloud and network providers the required flexibility to offer such on-demand resources. However, the maintenance of close computing resources presents a challenge when the served devices are on the move. In this case, if processing continuity is desired, a transference of processing resources and task state should be committed to maintain the service to end devices. The solution here presented, MIGRATE, proposes the concept of virtual mobile devices (vMDs) implemented as Virtual Functions (VxF) and acting as virtual representatives of physical processing devices. vMDs are instantiated at the edge of the access network, following a Multi-Access Edge Computing (MEC) approach, and move across different virtualisation domains. MIGRATE provides seamless and efficient transference of these software entities to follow the real location of mobile devices and continue supporting their physical counterparts. Software Defined Networks and Management and Operation functions are exploited to “migrate” vMDs to new virtualisation domains by forwarding data flows to the former domain until the new one is prepared, while a distributed data base avoids the transference of data. The solution has been deployed in a reference vehicular scenario at the Institute of Telecommunications Aveiro premises within the 5GINFIRE European project. In particular, the system has been evaluated under different virtualisation domains to study the operation of the migration approach in a vehicular monitoring scenario. The results validate the system from the application viewpoint with a Web monitoring tool, and the migration of the digital twin provided as VxF is analysed attending to the modification of data flows, indicating a seamless transition between virtualisation domains in a timely manner.publishe

Monitoramento da qualidade do ar no campus Três Poços em termos de partículas totais em suspensão

Segundo o INEA, Poeiras em suspensão no ar diminuem a capacidade de remoção das partículas pelo sistema respiratório e potencializam os efeitos dos gases. O objetivo desta pesquisa é monitorar a qualidade do ar no campus Três Poços do UniFoa, em termos de partículas totais em suspensão na bacia aérea local. Os resultados permitem um acompanhamento da qualidade do ar em todo o campus para um diagnóstico. Foram consideramos dados da estação meteorológicaem Volta Redonda – RJ. O monitoramento foi feito pelo Amostrador de Grande Volume para Partículas Totaisem Suspensão AGV PTS, o qual determina concentrações de partículas totais em suspensão (PTS). O equipamento foi calibrado por um calibrador portátil aferido pela empresa ENERGÉTICA em 25 / 05 / 2009 com prazo de validade 25 / 05 / 2010. O resultado da pesquisa é importante para todos os frequentadores do campus Três Poços, pois a qualidade do ar afeta o Meio Ambiente, a saúde e a qualidade de vida dos mesmos

Measurement of ϒ production in pp collisions at √s = 2.76 TeV

The production of ϒ(1S), ϒ(2S) and ϒ(3S) mesons decaying into the dimuon final state is studied with the LHCb detector using a data sample corresponding to an integrated luminosity of 3.3 pb−1 collected in proton–proton collisions at a centre-of-mass energy of √s = 2.76 TeV. The differential production cross-sections times dimuon branching fractions are measured as functions of the ϒ transverse momentum and rapidity, over the ranges pT < 15 GeV/c and 2.0 < y < 4.5. The total cross-sections in this kinematic region, assuming unpolarised production, are measured to be σ (pp → ϒ(1S)X) × B ϒ(1S)→μ+μ− = 1.111 ± 0.043 ± 0.044 nb, σ (pp → ϒ(2S)X) × B ϒ(2S)→μ+μ− = 0.264 ± 0.023 ± 0.011 nb, σ (pp → ϒ(3S)X) × B ϒ(3S)→μ+μ− = 0.159 ± 0.020 ± 0.007 nb, where the first uncertainty is statistical and the second systematic

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)

práticas artísticas no ensino básico e secundário

info:eu-repo/semantics/publishedVersio

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362