Improving die rework capability: Opportunities for using 3D non-contact measurement technology to reduce die tryout iterations to resolve dimensional issues

This report summarizes automotive body die tryout performance, based on a survey of and interviews with die manufacturing experts from automotive body manufacturers and die suppliers, The report explores opportunities for more effectively integrating new 3D noncontact optical measurement technologies during the die tryout process to improve performance. It provides basic guidelines for optical measurement data collection for stamping dies and resultant parts as well as analysis methods. For medium-complexity parts, the study participants estimate that a typical number of die tryout iterations is five to nine over a nine to 14 week period using typical North American tolerances and part acceptance criteria. The key enablers to reduce die tryout time were advancements in die forming and simulation software, particularly for complex materials, as well as advancements in virtual assembly tools.Center for Automotive Research, Ann Arbor, MINational Institute of Standards and Technology, Gaithersburg, MDhttp://deepblue.lib.umich.edu/bitstream/2027.42/61821/1/102174.pd

Integrating 3D non-contact measurement in the die tryout business process

Based on two surveys of manufacturers, this report summarizes several automotive body die tryout buyoff criteria, rework processes, and 3D non-contact measurement strategies. Relative to historical die tryout performance levels, a significant reduction in the number of iterations is clearly achievable through the following: Improved ability to create die compensation models to create new machine files to rework parts closer to nominal without significant unintended consequences. Changes to existing die and production source part approval processes to make better decisions about when rework is needed to produce a dimensionally acceptable body. Related to these improvements is the need for an effective business process integrating 3DNC measurement with new part approval processes to help manufacturers reduce the number of die rework iterations. A cowl top case study demonstrates the application of this process in effective use of 3DNC measurement to reduce the number of tryout iterations to only one rework loop.Center for Automotive Research, Ann Arbor, MINational Institute of Standards and Technology, Gaithersburg, MDhttp://deepblue.lib.umich.edu/bitstream/2027.42/61820/3/102173.pd

Datum transformation analysis for production part approval using 3D non-contact measurement

This paper presents a comprehensive dimensional validation methodology, known as datum transformation analysis (DTA). The DTA approach utilizes 3D non-contact (3DNC) measurement to obtain a full part dimensional representation at all critical matching interfaces of a part assembly to the vehicle. Next, a part measurement re-alignment process is applied to identify new positions for the assembly datum locators that optimize the overall product quality at these matching interfaces. Next, datum locations are adjusted at the component level (at the same physical location as the corresponding assembly) to improve mean conformance of the assembly dimensions. The adjustments to the datum locators at the component level are not necessarily made to improve component quality, but rather to optimize final part assembly. This DTA methodology is demonstrated using an automotive headlamp assembly. In this case study, we identify tooling rework moves using DTA to increase the percent of critical assembly dimensions whose mean values are within ±0.25 millimeters from 20% to 90%.Visteonhttp://deepblue.lib.umich.edu/bitstream/2027.42/61819/1/102172.pd

Quantifying alignment effects in 3D coordinate measurement

The use of fixtureless, non-contact coordinate measurement has become increasingly prevalent in manufacturing problem solving. Manufacturers now routinely use measurement systems such as white light area scanners, photogrammetry, laser trackers, and portable laser scanners to conduct studies that require measuring upstream supplier parts, tooling, or in-process subassemblies. For part measurements in these studies, certified fixtures with alignment features such as tooling balls often are not available. Instead, manufacturers rely on ad hoc part-holding fixtures or measure parts without fixtures and perform alignments mathematically. Here, advancements in software are providing operators with numerous alignment options, and users are actively using this functionality. Naturally, these additional capabilities have led to inconsistencies in the alignment method used across measurement studies, often affecting dimensional results. This paper reviews several common alignment or registration methods and provides a metric to assess systematic alignment error. To demonstrate alignment effects, we present a measurement system study of a moderately complex part requiring an over-constrained datum scheme. We first measure the part using a conventional fixture-based method to establish a baseline for static and dynamic repeatability. We then compare these with results from two mathematically-based iterative alignment methods based on fixtureless measurement. Next, we assess the systematic alignment error between the different fixture/alignment alternatives. We show that for the same basic datum scheme provided on engineering drawings, the systematic alignment error is a far more significant issue for problem solving than the repeatability error or equipment accuracy.http://deepblue.lib.umich.edu/bitstream/2027.42/69245/1/99983.pd

Notes towards a history of Khoi literature

This article puts forward a revisionist history of Khoi literature, and also presents a number of translated Khoi narratives that have not been available in English before. Compared to the large volume of Bushman literature and scholarship, there has been very little Khoi literature and engagement with it, and an argument is presented to account for this gap in South African cultural history. Until now, the major source of Khoi literature was Wilhelm Bleek’s Reynard the Fox in South Africa (1864), and this text is critically interrogated as a limiting version of Khoi orature. An alternative corpus of Khoi narratives is presented that was originally published in Leonard Schultze’s Aus Namaland und Kalahari (1907).Web of Scienc

Linking soil microbial community structure to potential carbon mineralization: A continental scale assessment of reduced tillage

Potential carbon mineralization (Cmin) is a commonly used indicator of soil health, with greater Cmin values interpreted as healthier soil. While Cmin values are typically greater in agricultural soils managed with minimal physical disturbance, the mechanisms driving the increases remain poorly understood. This study assessed bacterial and archaeal community structure and potential microbial drivers of Cmin in soils maintained under various degrees of physical disturbance. Potential carbon mineralization, 16S rRNA sequences, and soil characterization data were collected as part of the North American Project to Evaluate Soil Health Measurements (NAPESHM). Results showed that type of cropping system, intensity of physical disturbance, and soil pH influenced microbial sensitivity to physical disturbance. Furthermore, 28% of amplicon sequence variants (ASVs), which were important in modeling Cmin, were enriched under soils managed with minimal physical disturbance. Sequences identified as enriched under minimal disturbance and important for modeling Cmin, were linked to organisms which could produce extracellular polymeric substances and contained metabolic strategies suited for tolerating environmental stressors. Understanding how physical disturbance shapes microbial communities across climates and inherent soil properties and drives changes in Cmin provides the context necessary to evaluate management impacts on standardized measures of soil microbial activity

Linking soil microbial community structure to potential carbon mineralization: A continental scale assessment of reduced tillage

Potential carbon mineralization (Cmin) is a commonly used indicator of soil health, with greater Cmin values interpreted as healthier soil. While Cmin values are typically greater in agricultural soils managed with minimal physical disturbance, the mechanisms driving the increases remain poorly understood. This study assessed bacterial and archaeal community structure and potential microbial drivers of Cmin in soils maintained under various degrees of physical disturbance. Potential carbon mineralization, 16S rRNA sequences, and soil characterization data were collected as part of the North American Project to Evaluate Soil Health Measurements (NAPESHM). Results showed that type of cropping system, intensity of physical disturbance, and soil pH influenced microbial sensitivity to physical disturbance. Furthermore, 28% of amplicon sequence variants (ASVs), which were important in modeling Cmin, were enriched under soils managed with minimal physical disturbance. Sequences identified as enriched under minimal disturbance and important for modeling Cmin, were linked to organisms which could produce extracellular polymeric substances and contained metabolic strategies suited for tolerating environmental stressors. Understanding how physical disturbance shapes microbial communities across climates and inherent soil properties and drives changes in Cmin provides the context necessary to evaluate management impacts on standardized measures of soil microbial activity

A novel formulation of inhaled sodium cromoglicate (PA101) in idiopathic pulmonary fibrosis and chronic cough: a randomised, double-blind, proof-of-concept, phase 2 trial

Background Cough can be a debilitating symptom of idiopathic pulmonary fibrosis (IPF) and is difficult to treat. PA101 is a novel formulation of sodium cromoglicate delivered via a high-efficiency eFlow nebuliser that achieves significantly higher drug deposition in the lung compared with the existing formulations. We aimed to test the efficacy and safety of inhaled PA101 in patients with IPF and chronic cough and, to explore the antitussive mechanism of PA101, patients with chronic idiopathic cough (CIC) were also studied. Methods This pilot, proof-of-concept study consisted of a randomised, double-blind, placebo-controlled trial in patients with IPF and chronic cough and a parallel study of similar design in patients with CIC. Participants with IPF and chronic cough recruited from seven centres in the UK and the Netherlands were randomly assigned (1:1, using a computer-generated randomisation schedule) by site staff to receive PA101 (40 mg) or matching placebo three times a day via oral inhalation for 2 weeks, followed by a 2 week washout, and then crossed over to the other arm. Study participants, investigators, study staff, and the sponsor were masked to group assignment until all participants had completed the study. The primary efficacy endpoint was change from baseline in objective daytime cough frequency (from 24 h acoustic recording, Leicester Cough Monitor). The primary efficacy analysis included all participants who received at least one dose of study drug and had at least one post-baseline efficacy measurement. Safety analysis included all those who took at least one dose of study drug. In the second cohort, participants with CIC were randomly assigned in a study across four centres with similar design and endpoints. The study was registered with ClinicalTrials.gov (NCT02412020) and the EU Clinical Trials Register (EudraCT Number 2014-004025-40) and both cohorts are closed to new participants. Findings Between Feb 13, 2015, and Feb 2, 2016, 24 participants with IPF were randomly assigned to treatment groups. 28 participants with CIC were enrolled during the same period and 27 received study treatment. In patients with IPF, PA101 reduced daytime cough frequency by 31·1% at day 14 compared with placebo; daytime cough frequency decreased from a mean 55 (SD 55) coughs per h at baseline to 39 (29) coughs per h at day 14 following treatment with PA101, versus 51 (37) coughs per h at baseline to 52 (40) cough per h following placebo treatment (ratio of least-squares [LS] means 0·67, 95% CI 0·48–0·94, p=0·0241). By contrast, no treatment benefit for PA101 was observed in the CIC cohort; mean reduction of daytime cough frequency at day 14 for PA101 adjusted for placebo was 6·2% (ratio of LS means 1·27, 0·78–2·06, p=0·31). PA101 was well tolerated in both cohorts. The incidence of adverse events was similar between PA101 and placebo treatments, most adverse events were mild in severity, and no severe adverse events or serious adverse events were reported. Interpretation This study suggests that the mechanism of cough in IPF might be disease specific. Inhaled PA101 could be a treatment option for chronic cough in patients with IPF and warrants further investigation