82 research outputs found

    Emplacement and segment geometry of large, high-viscosity magmatic sheets

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    This project and Tobias Schmiedel are funded by the Knut and Alice Wallenberg Foundation through a Wallenberg Academy Fellow grant to Steffi Burchardt (grant No. KAW 2017.0153).Understanding magma transport in sheet intrusions is crucial to interpreting volcanic unrest. Studies of dyke emplacement and geometry focus predominantly on low-viscosity, mafic dykes. Here, we present an in-depth study of two high-viscosity dykes (106 Pa·s) in the Chachahuén volcano, Argentina, the Great Dyke and the Sosa Dyke. To quantify dyke geometries, magma flow indicators, and magma viscosity, we combine photogrammetry, microstructural analysis, igneous petrology, Fourier-Transform-Infrared-Spectroscopy, and Anisotropy of Magnetic Susceptibility (AMS). Our results show that the dykes consist of 3 to 8 mappable segments up to 2 km long. Segments often end in a bifurcation, and segment tips are predominantly oval, but elliptical tips occur in the outermost segments of the Great Dyke. Furthermore, variations in host rocks have no observable impact on dyke geometry. AMS fabrics and other flow indicators in the Sosa Dyke show lateral magma flow in contrast to the vertical flow suggested by the segment geometries. A comparison with segment geometries of low-viscosity dykes shows that our high-viscosity dykes follow the same geometrical trend. In fact, the data compilation supports that dyke segment and tip geometries reflect different stages in dyke emplacement, questioning the current usage for final sheet geometries as proxies for emplacement mechanism.Publisher PDFPeer reviewe

    Genomic Damage in Endstage Renal Disease—Contribution of Uremic Toxins

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    Patients with end-stage renal disease (ESRD), whether on conservative, peritoneal or hemodialysis therapy, have elevated genomic damage in peripheral blood lymphocytes and an increased cancer incidence, especially of the kidney. The damage is possibly due to accumulation of uremic toxins like advanced glycation endproducts or homocysteine. However, other endogenous substances with genotoxic properties, which are increased in ESRD, could be involved, such as the blood pressure regulating hormones angiotensin II and aldosterone or the inflammatory cytokine TNF-α. This review provides an overview of genomic damage observed in ESRD patients, focuses on possible underlying causes and shows modulations of the damage by modern dialysis strategies and vitamin supplementation

    ATG24 represses autophagy and differentiation and is essential for homeostasy of the flagellar pocket in trypanosoma brucei

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    We have previously identified homologs for nearly half of the approximately 30 known yeast Atg's in the genome database of the human sleeping sickness parasite Trypanosoma brucei. So far, only a few of these homologs have their role in autophagy experimentally confirmed. Among the candidates was the ortholog of Atg24 that is involved in pexophagy in yeast. In T. brucei, the peroxisome-like organelles named glycosomes harbor core metabolic processes, especially glycolysis. In the autotrophic yeast, autophagy is essential for adaptation to different nutritional environments by participating in the renewal of the peroxisome population. We hypothesized that autophagic turnover of the parasite's glycosomes plays a role in differentiation during its life cycle, which demands adaptation to different host environments and associated dramatic changes in nutritional conditions. We therefore characterized T. brucei ATG24, the T. brucei ortholog of yeast Atg24 and mammalian SNX4, and found it to have a regulatory role in autophagy and differentiation as well as endocytic trafficking. ATG24 partially localized on endocytic membranes where it was recruited via PI3-kinase III/VPS34. ATG24 silencing severely impaired receptor-mediated endocytosis of transferrin, but not adsorptive uptake of a lectin, and caused a major enlargement of the flagellar pocket. ATG24 silencing approximately doubled the number of autophagosomes, suggesting a role in repressing autophagy, and strongly accelerated differentiation, in accordance with a role of autophagy in parasite differentiation. Overexpression of the two isoforms of T. brucei ATG8 fused to GFP slowed down differentiation, possibly by a dominant-negative effect. This was overcome by ATG24 depletion, further supporting its regulatory role

    Three Saturn-mass planets transiting F-type stars revealed with TESS and HARPS

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    While the sample of confirmed exoplanets continues to increase, the population of transiting exoplanets around early-type stars is still limited. These planets allow us to investigate the planet properties and formation pathways over a wide range of stellar masses and study the impact of high irradiation on hot Jupiters orbiting such stars. We report the discovery of TOI-615b, TOI-622b, and TOI-2641b, three Saturn-mass planets transiting main sequence, F-type stars. The planets were identified by the Transiting Exoplanet Survey Satellite (TESS) and confirmed with complementary ground-based and radial velocity observations. TOI-615b is a highly irradiated (∌\sim1277 F⊕F_{\oplus}) and bloated Saturn-mass planet (1.69−0.06+0.05^{+0.05}_{-0.06}RJupR_{Jup} and 0.43−0.08+0.09^{+0.09}_{-0.08}MJupM_{Jup}) in a 4.66 day orbit transiting a 6850 K star. TOI-622b has a radius of 0.82−0.03+0.03^{+0.03}_{-0.03}RJupR_{Jup} and a mass of 0.30−0.08+0.07^{+0.07}_{-0.08}~MJupM_{Jup} in a 6.40 day orbit. Despite its high insolation flux (∌\sim600 F⊕F_{\oplus}), TOI-622b does not show any evidence of radius inflation. TOI-2641b is a 0.37−0.04+0.05^{+0.05}_{-0.04}MJupM_{Jup} planet in a 4.88 day orbit with a grazing transit (b = 1.04−0.06+0.05^{+0.05}_{-0.06 }) that results in a poorly constrained radius of 1.61−0.64+0.46^{+0.46}_{-0.64}RJupR_{Jup}. Additionally, TOI-615b is considered attractive for atmospheric studies via transmission spectroscopy with ground-based spectrographs and JWST\textit{JWST}. Future atmospheric and spin-orbit alignment observations are essential since they can provide information on the atmospheric composition, formation and migration of exoplanets across various stellar types.Comment: 16 pages, 17 figures, submitted to A&

    Planning at the national level

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    International comparative planning

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    Characterization of a hybrid active-passive absorber by means of Laser Doppler Velocimetry

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    National audienceThe LMFA has been developing hybrid absorbers for about 10 years now. Combining passive absorption and active control, these absorbers are well suited to applications that feature a grazing flow. The absorber consists of distinct cells covered by a thin porous layer, each cell containing a control microphone and a secondary source. Active control is used to reduce the acoustic pressure at the rear side of the porous layer at low frequencies. This results in a cancellation of the imaginary part of the surface impedance and permits to approach optimal impedance, i.e. the one that results in maximum noise reduction. The presence of a uniform grazing flow has little influence on optimal impedance. The control system being well protected against the flow, there are by the way no convergence or stability problems. However, the performance of the absorber decreases significantly in presence of grazing flow. In order to explore the origin of this behavior, an absorber composed of three hybrid cells has been tested in the “B2A” test bench at ONERA Toulouse. Laser Doppler Velocimetry (LDV) measurements are performed that permit to assess acoustic velocity in a plane above the hybrid liner in a non-intrusive way. These measurements confirm the good performance without flow. In particular, one observes that the three cells cannot be distinguished anymore but appear as a homogeneous impedance surface. The absorber has a rather global influence on the duct. In presence of a grazing flow of bulk Mach number 0.1, however, the influence of the absorber on the duct is reduced on the immediate vicinity of each hybrid cell

    Dynamics of Surface Deformation Induced By Dikes and Cone Sheets in a Cohesive Brittle Coulomb Crust Data

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    Two files containing raw surface monitoring data from two experimental series and one file containing the analysis of the processed surface monitoring data
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