11 research outputs found
First Results from the DRIFT-IIa Dark Matter Detector
Data from the DRIFT-IIa directional dark matter experiment are presented,
collected during a near continuous 6 month running period. A detailed
calibration analysis comparing data from gamma-ray, x-ray and neutron sources
to a GEANT4 Monte Carlo simulations reveals an efficiency for detection of
neutron induced recoils of 94+/-2(stat.)+/-5(sys.)%. Software-based cuts,
designed to remove non-nuclear recoil events, are shown to reject 60Co
gamma-rays with a rejection factor of better than 8x10-6 for all energies above
threshold. An unexpected event population has been discovered and is shown here
to be due to the alpha-decay of 222Rn daughter nuclei that have attached to the
central cathode. A limit on the flux of neutrons in the Boulby Underground
Laboratory is derived from analysis of unshielded and shielded data.Comment: 43 pages, 14 figures, submitted to Astroparticle Physic
Track Reconstruction and Performance of DRIFT Directional Dark Matter Detectors using Alpha Particles
First results are presented from an analysis of data from the DRIFT-IIa and
DRIFT-IIb directional dark matter detectors at Boulby Mine in which alpha
particle tracks were reconstructed and used to characterise detector
performance--an important step towards optimising directional technology. The
drift velocity in DRIFT-IIa was [59.3 +/- 0.2 (stat) +/- 7.5 (sys)] m/s based
on an analysis of naturally-occurring alpha-emitting background. The drift
velocity in DRIFT-IIb was [57 +/- 1 (stat) +/- 3 (sys)] m/s determined by the
analysis of alpha particle tracks from a Po-210 source. 3D range reconstruction
and energy spectra were used to identify alpha particles from the decay of
Rn-222, Po-218, Rn-220 and Po-216. This study found that (22 +/- 2)% of Po-218
progeny (from Rn-222 decay) are produced with no net charge in 40 Torr CS2. For
Po-216 progeny (from Rn-220 decay) the uncharged fraction is (100 +0 -35)%.Comment: 27 pages, 12 figures, 5 tables. Submitted to Nuclear Instruments and
Methods in Physics Research, Section A. Subj-class: Instrumentation and
Detector
The ZEPLIN II dark matter detector: data acquisition system and data reduction
ZEPLIN-II is a two-phase (liquid/gas) xenon dark matter detector searching
for WIMP-nucleon interactions. In this paper we describe the data acquisition
system used to record the data from ZEPLIN-II and the reduction procedures
which parameterise the data for subsequent analysis.Comment: 11 pages, 10 figure
The ZEPLIN II dark matter detector: data acquisition system and data reduction
ZEPLIN-II is a two-phase (liquid/gas) xenon dark matter detector searching
for WIMP-nucleon interactions. In this paper we describe the data acquisition
system used to record the data from ZEPLIN-II and the reduction procedures
which parameterise the data for subsequent analysis.Comment: 11 pages, 10 figure
Limits on spin-dependent WIMP-nucleon cross-sections from the first ZEPLIN-II data
The first underground data run of the ZEPLIN-II experiment has set a limit on
the nuclear recoil rate in the two-phase xenon detector for direct dark matter
searches. In this paper the results from this run are converted into the limits
on spin-dependent WIMP-proton and WIMP-neutron cross-sections. The minimum of
the curve for WIMP-neutron cross-section corresponds to 0.07 pb at a WIMP mass
of around 65 GeV.Comment: 12 pages, 2 figures, to be published in Physics Letters
Measurement of the Range Component Directional Signature in a DRIFT-II Detector using 252Cf Neutrons
The DRIFT collaboration utilizes low pressure gaseous detectors to search for
WIMP dark matter with directional signatures. A 252Cf neutron source was placed
on each of the principal axes of a DRIFT detector in order to test its ability
to measure directional signatures from the three components of very low energy
(~keV/amu) recoil ranges. A high trigger threshold and the event selection
procedure ensured that only sulfur recoils were analyzed. Sulfur recoils
produced in the CS2 target gas by the 252Cf source closely match those expected
from massive WIMP induced sulfur recoils. For each orientation of the source a
directional signal from the range components was observed, indicating that the
detector is directional along all 3 axes. An analysis of these results yields
an optimal orientation for DRIFT detectors when searching for a directional
signature from WIMPs. Additional energy dependent information is provided to
aid in understanding this effect.Comment: 14 pages, 1 Table, 8 Figure
AD51B in Familial Breast Cancer
Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of female breast cancer and rs1314913 with the risk of male breast cancer. The aim of this study was to investigate the role of RAD51B variants in breast cancer predisposition, particularly in the context of familial breast cancer in Finland. We sequenced the coding region of RAD51B in 168 Finnish breast cancer patients from the Helsinki region for identification of possible recurrent founder mutations. In addition, we studied the known rs999737, rs2588809, and rs1314913 SNPs and RAD51B haplotypes in 44,791 breast cancer cases and 43,583 controls from 40 studies participating in the Breast Cancer Association Consortium (BCAC) that were genotyped on a custom chip (iCOGS). We identified one putatively pathogenic missense mutation c.541C>T among the Finnish cancer patients and subsequently genotyped the mutation in additional breast cancer cases (n = 5259) and population controls (n = 3586) from Finland and Belarus. No significant association with breast cancer risk was seen in the meta-analysis of the Finnish datasets or in the large BCAC dataset. The association with previously identified risk variants rs999737, rs2588809, and rs1314913 was replicated among all breast cancer cases and also among familial cases in the BCAC dataset. The most significant association was observed for the haplotype carrying the risk-alleles of all the three SNPs both among all cases (odds ratio (OR): 1.15, 95% confidence interval (CI): 1.11–1.19, P = 8.88 x 10−16) and among familial cases (OR: 1.24, 95% CI: 1.16–1.32, P = 6.19 x 10−11), compared to the haplotype with the respective protective alleles. Our results suggest that loss-of-function mutations in RAD51B are rare, but common variation at the RAD51B region is significantly associated with familial breast cancer risk
The Relationship between Nursing Leadership and Patient Outcomes: A Systematic Review
Aim: The purpose of this review was to describe findings of a systematic review of studies that examine the relationship between nursing leadership and patient outcomes.
Background: With recent attention directed to the creation of safer practice environments for patients, nursing leadership is called on to advance this agenda within organizations. However, surprisingly little is known about the actual association between nursing leadership and patient outcomes.
Methods: Published English-only research articles that examined formal nursing leadership and patient outcomes were selected from computerized databases and manual searches. Data extraction and methodological quality assessment were completed for the final seven quantitative research articles.
Results: Evidence of significant associations between positive leadership behaviours, styles or practices and increased patient satisfaction and reduced adverse events were found. Findings relating leadership to patient mortality rates were inconclusive.
Conclusion: The findings of this review suggest that an emphasis on developing transformational nursing leadership is an important organizational strategy to improve patient outcomes
The ZEPLIN III Detector; Results from Surface Calibrations
ZEPLIN-III is a direct dark-matter search instrument using liquid xenon as a target.Both the scintillation light and the ionisation charge are measured.The instrument has been built and it is currently being testing in a surface laboratory.We present results from some of the initial testing, including design thermal control system verification, photomultiplier calibration (including spectral measurements with 60 keV photons from 241Am) and two-phase operation showing simultaneous measurement of scintillation and charge and position reconstruction