Antenatal Microbial Colonization of Mammalian Gut

The widely accepted dogma of intrauterine sterility and initial colonization of the newborn during birth has been blurred by recent observations of microbial presence in meconium, placenta, and amniotic fluid. Given the importance of a maternal-derived in utero infant seeding, it is crucial to exclude potential environmental or procedural contaminations and to assess fetal colonization before parturition. To this end, we analyzed sterilely collected intestinal tissues, placenta, and amniotic fluid from rodent fetuses and tissues from autoptic human fetuses. Total bacterial DNA was extracted from collected samples and analyzed by Next Generation Sequencing (NGS) techniques using hypervariable 16S ribosomal RNA (rRNA) regions (V3-V4). Colonizing microbes were visualized in situ, using labeled probes targeting 16S ribosomal DNA by fluorescent in situ hybridization. The NGS analysis showed the presence of pioneer microbes in both rat and human intestines as well as in rodent placentas and amniotic fluids. Microbial communities showed fetus- and dam-dependent clustering, confirming the high interindividual variability of commensal microbiota even in the antenatal period. Fluorescent in situ hybridization analysis confirmed the microbes' presence in the lumen of the developing gut. These findings suggest a possible antenatal colonization of the developing mammalian gut

Evidence for two-quark content of f0(980)f_{0}(980) in exclusive b→cb\to c decays

Inspired by a large decay branching ratio (BR) of $B^{+}\to f_{0}(980)K^{+}$ measured by Belle recently, we propose that a significant evidence of the component of $n\bar{n}=(u\bar{u}+d\bar{d})/\sqrt{2}$ in $f_{0}(980)$ could be demonstrated in exclusive $b\to c$ decays by the observation of $f_{0}(980)$ in the final states $\bar{B}\to D^{0(*)} \pi^{+} \pi^{-}(KK)$ and $\bar{B}\to J/\Psi \pi^{+} \pi^{-}(KK)$. We predict the BRs of $\bar{B}\to D^{0(*)} (J/\Psi) f_{0}(980)$ to be ${\cal {O}}(10^{-4})$ (${\cal {O}}(10^{-5})$) while the unknown wave functions of $D^{(*)0}$ ($J/\Psi$) are chosen to fit the observed decays of $\bar{B}\to D^{(*)0} \pi^{0} (J/\Psi K^{0(*)})$.Comment: 4 pages, 2 figures, Revtex4, version to appear in PR

On the Resummed Hadronic Spectra of Inclusive B Decays

In this paper we investigate the hadronic mass spectra of inclusive B decays. Specifically, we study how an upper cut on the invariant mass spectrum, which is necessary to extract V_{ub}, results in the breakdown of the standard perturbative expansion due to the existence of large infrared logs. We first show how the decay rate factorizes at the level of the double differential distribution. Then, we present closed form expressions for the resummed cut rate for the inclusive decays B -> X_s gamma and B -> X_u e nu at next-to-leading order in the infrared logs. Using these results, we determine the range of cuts for which resummation is necessary, as well as the range for which the resummed expansion itself breaks down. We also use our results to extract the leading and next to leading infrared log contribution to the two loop differential rate. We find that for the phenomenologically interesting cut values, there is only a small region where the calculation is under control. Furthermore, the size of this region is sensitive to the parameter \bar{\Lambda}. We discuss the viability of extracting V_{ub} from the hadronic mass spectrum.Comment: 18 pages, 5 figures, minor change

Strong coupling of excited heavy mesons

We compute the strong coupling constant $G_{B^{**} B \pi} \; (G_{D^{**} D \pi})$, where $B^{**}$ ($D^{**}$) is the $0^+$ $P-$wave $b \bar q \; (c \bar q)$ state, by QCD sum rules and by light-cone sum rules. The two methods give compatible results in the limit $m_Q \to \infty$, with a rather large value of the coupling constant. We apply the results to the calculation of the hadronic widths of the positive parity $B$ and $D$ states and to the chiral loop contribution to the ratio $f_{D_s}/f_D$.Comment: 31 pages, RevTeX, 4 figures appended as uuencoded fil

Young and Intermediate-age Distance Indicators

Distance measurements beyond geometrical and semi-geometrical methods, rely mainly on standard candles. As the name suggests, these objects have known luminosities by virtue of their intrinsic proprieties and play a major role in our understanding of modern cosmology. The main caveats associated with standard candles are their absolute calibration, contamination of the sample from other sources and systematic uncertainties. The absolute calibration mainly depends on their chemical composition and age. To understand the impact of these effects on the distance scale, it is essential to develop methods based on different sample of standard candles. Here we review the fundamental properties of young and intermediate-age distance indicators such as Cepheids, Mira variables and Red Clump stars and the recent developments in their application as distance indicators.Comment: Review article, 63 pages (28 figures), Accepted for publication in Space Science Reviews (Chapter 3 of a special collection resulting from the May 2016 ISSI-BJ workshop on Astronomical Distance Determination in the Space Age

Measurement of (anti)deuteron and (anti)proton production in DIS at HERA

The first observation of (anti)deuterons in deep inelastic scattering at HERA has been made with the ZEUS detector at a centre-of-mass energy of 300--318 GeV using an integrated luminosity of 120 pb-1. The measurement was performed in the central rapidity region for transverse momentum per unit of mass in the range 0.3<p_T/M<0.7. The particle rates have been extracted and interpreted in terms of the coalescence model. The (anti)deuteron production yield is smaller than the (anti)proton yield by approximately three orders of magnitude, consistent with the world measurements.Comment: 26 pages, 9 figures, 5 tables, submitted to Nucl. Phys.

Anisotropy studies around the galactic centre at EeV energies with the Auger Observatory

Data from the Pierre Auger Observatory are analyzed to search for anisotropies near the direction of the Galactic Centre at EeV energies. The exposure of the surface array in this part of the sky is already significantly larger than that of the fore-runner experiments. Our results do not support previous findings of localized excesses in the AGASA and SUGAR data. We set an upper bound on a point-like flux of cosmic rays arriving from the Galactic Centre which excludes several scenarios predicting sources of EeV neutrons from Sagittarius $A$. Also the events detected simultaneously by the surface and fluorescence detectors (the `hybrid' data set), which have better pointing accuracy but are less numerous than those of the surface array alone, do not show any significant localized excess from this direction.Comment: Matches published versio

Gluons and the quark sea at high energies: distributions, polarization, tomography

This report is based on a ten-week program on "Gluons and the quark sea at high-energies", which took place at the Institute for Nuclear Theory in Seattle in Fall 2010. The principal aim of the program was to develop and sharpen the science case for an Electron-Ion Collider (EIC), a facility that will be able to collide electrons and positrons with polarized protons and with light to heavy nuclei at high energies, offering unprecedented possibilities for in-depth studies of quantum chromodynamics. This report is organized around four major themes: i) the spin and flavor structure of the proton, ii) three-dimensional structure of nucleons and nuclei in momentum and configuration space, iii) QCD matter in nuclei, and iv) Electroweak physics and the search for physics beyond the Standard Model. Beginning with an executive summary, the report contains tables of key measurements, chapter overviews for each of the major scientific themes, and detailed individual contributions on various aspects of the scientific opportunities presented by an EIC.Comment: 547 pages, A report on the joint BNL/INT/Jlab program on the science case for an Electron-Ion Collider, September 13 to November 19, 2010, Institute for Nuclear Theory, Seattle; v2 with minor changes, matches printed versio

Deep inelastic inclusive and diffractive scattering at Q2Q^2 values from 25 to 320 GeV2^2 with the ZEUS forward plug calorimeter

Deep inelastic scattering and its diffractive component, $ep \to e^{\prime}\gamma^* p \to e^{\prime}XN$, have been studied at HERA with the ZEUS detector using an integrated luminosity of 52.4 pb$^{-1}$. The $M_X$ method has been used to extract the diffractive contribution. A wide range in the centre-of-mass energy $W$ (37 -- 245 GeV), photon virtuality $Q^2$ (20 -- 450 GeV$^2$) and mass $M_X$ (0.28 -- 35 GeV) is covered. The diffractive cross section for $2 < M_X < 15$ GeV rises strongly with $W$, the rise becoming steeper as $Q^2$ increases. The data are also presented in terms of the diffractive structure function, $F^{\rm D(3)}_2$, of the proton. For fixed $Q^2$ and fixed $M_X$, \xpom F^{\rm D(3)}_2 shows a strong rise as \xpom \to 0, where \xpom is the fraction of the proton momentum carried by the Pomeron. For Bjorken-$x < 1 \cdot 10^{-3}$, \xpom F^{\rm D(3)}_2 shows positive $\log Q^2$ scaling violations, while for $x \ge 5 \cdot 10^{-3}$ negative scaling violations are observed. The diffractive structure function is compatible with being leading twist. The data show that Regge factorisation is broken.Comment: 89 pages, 27 figure