10 research outputs found
The genetic architecture of the human cerebral cortex
- Author
- Adams Hieab H H
- Adams Hieab H H
- Agartz Ingrid
- Ahlijanian Michael
- Ahmad Shahzad
- Ainscough Susan
- Aisen Paul
- Albers Colleen S
- Albert Marilyn
- Alhusaini Saud
- Allard Joanne
- Almeida Marcio A A
- Alnæs Dag
- Alvim Marina K M
- Ames David
- Ames David
- Amin Najaf
- Amlien Inge K
- Amouyel Philippe
- Ances Beau
- Anderson Karen
- Anderson Tim J
- Andersson Micael
- Andreassen Ole A
- Andreassen Ole A
- Apostolova Liana
- Ard Tyler
- Arias-Vasquez Alejandro
- Armstrong Nicola J
- Armstrong Nicola J
- Arnedo Vanessa
- Arnold Steven E
- Artiges Eric
- Artiges Eric
- Ashley-Koch Allison
- Assaly Michele
- Assareh Amelia A
- Asthana Sanjay
- Atkins Joshua R
- Aydin Semiha
- Ayesa-Arriola Rosa
- Baca Marne
- Bachman David
- Banaschewski Tobias
- Barbot Alexis
- Barker Gareth
- Barone Paolo
- Bartha Rob
- Bartzokis George
- Bastin Mark E
- Bastin Mark E
- Bates Vernice
- Baune Bernhard T
- Becerra Mauricio
- Becker Andreas
- Becker James T
- Beckett Laurel
- Beckham Jean C
- Beiser Alexa S
- Belden Christine M
- Belger Aysenil
- Bell Karen L
- Berg Daniela
- Bergman Howard
- Bernard Manon
- Bernard Manon
- Bernick Charles
- Bernstein Matthew
- Beyer Frauke
- Bezivin-Frere Pauline
- Biondo Francesca
- Bis Joshua C
- Bis Joshua C
- Bishop Courtney
- Black Sandra
- Blangero John
- Blank Karen
- Bodge Courtney
- Bokde Arun
- Bonakdarpour Borna
- Boomsma Dorret I
- Borges-Neto Salvador
- Borowski Bret
- Borrie Michael
- Bralten Janita
- Brand Connie
- Brandabur Melanie
- Brandt Christine L
- Brewer James
- Brockington John
- Brodaty Henry
- Brodaty Henry
- Bromberg Uli
- Brooks David
- Brooks William M
- Brosch Jared R
- Brouwer Rachel M
- Brown Gregory G
- Bruehl Ruediger
- Brunner Han G
- Buckholtz Neil
- Buckner Randy L
- Budson Andrew E
- Buimer Elizabeth E L
- Buitelaar Jan K
- Burke Anna
- Burns Jeffrey M
- Bustillo Juan R
- Bülow Robin
- Bülow Robin
- Bürger Christian
- Bÿchel Christian
- Cabrera Yuliana
- Cahn Wiepke
- Cairns Murray J
- Cairns Nigel J
- Calhoun Vince
- Cannon Dara M
- Capote Horacio
- Carlsson Cynthia M
- Carmichael Owen
- Carr Vaughan J
- Carrillo Maria
- Carroll Maria
- Carson Richard E
- Carter Raina
- Casaceli Cynthia
- Casalin Paola
- Caseras Xavier
- Caspell Chelsea
- Caspers Svenja
- Catafau Ana
- Cavalleri Gianpiero L
- Cedarbaum Jesse
- Cellar Janet S
- Celmins Dzintra
- Cendes Fernando
- Chahine Lama
- Chakravarty Mallar
- Chalker Alison
- Chao Steven
- Chen Kewei
- Chen Qiang
- Chertkow Howard
- Cheung Joshua W
- Chiang Gloria
- Ching Christopher R K
- Chowdhury Munir
- Chowdhury Sohini
- Chu Congying
- Cichon Sven
- Clark Christopher M
- Clark David
- Coffey Christopher
- Coleman Edward
- Colodro-Conde Lucía
- Comery Thomas
- Conrad Gary
- Conrod Patricia
- Consortium CHARGE
- Consortium Enhancing NeuroImaging Genetics through Meta-Analysis
- Consortium EPIGEN
- Consortium IMAGEN
- Consortium SYS
- Correia Stephen
- Corvin Aiden
- Couvy-Duchesne Baptiste
- Crawford Karen
- Creech Mary L
- Crespo-Facorro Benedicto
- Crivello Fabrice
- Curran Joanne E
- D'Agostino Daniel
- Daedelow Laura
- Daiello Lori A
- Dale Anders M
- Dale Anders M
- Dalley Jeffrey
- Dalrymple-Alford John C
- Dalvie Shareefa
- Dang Mimi
- Dannlowski Udo
- Darin Abigail
- Davies Gareth E
- Davies Peter
- de Araujo Tânia K
- de Geus Eco J C
- de Zubicaray Greig I
- de Zwarte Sonja M C
- Deary Ian J
- Deary Ian J
- Debette Stephanie
- Debette Stephanie
- Decarli Charles
- DeCarli Charles
- Deeley Cheryl
- Degenhardt Franziska
- Delanty Norman
- DeMarco Kathryn
- den Braber Anouk
- Dennis Michelle F
- Depondt Chantal
- Desrivieres Sylvane
- Desrivières Sylvane
- Dietsche Bruno
- Djurovic Srdjan
- Doan Nhat Trung
- Doherty Colin P
- Dohm Katharina
- Dolen Sara
- Donohoe Gary
- Donohue Michael
- Doody Rachelle S
- Dooley Eoin
- Doraiswamy P Murali
- Drost Dick
- Duara Ranjan
- Dubow Jordan S
- Dunlop Becky
- Egebjerg Jan
- Ehrlich Stefan
- El Khouli Riham
- Engelbrecht Hannah-Ruth
- Erk Susanne
- Espay Alberto
- Espay Kristy
- Espeseth Thomas
- Espiritu Ryan
- Faber Kelley
- Factor Stewart
- Fan Chun Chieh
- Fargher Kristin
- Farlow Martin R
- Fatica Parianne
- Fedko Iryna O
- Feldman Howard
- Fernandez Hubert
- Fernández Guillén
- Figurski Michal
- Filippi Irina
- Fillit Howard
- Fillmer Ariane
- Finger Elizabeth
- Fisher Simon E
- Flashman Laura A
- Fleisher Adam
- Fletcher Evan
- Flor Herta
- Flor Herta
- Foley Sonya F
- Fontaine Deborah
- Fontoura Paulo
- Ford Judith M
- Fornage Myriam
- Fornage Myriam
- Foroud Tatiana
- Foroud Tatiana M
- Forstner Andreas J
- Foster Eric
- Foster Norm
- Fox Nick
- Francks Clyde
- Frank Richard
- Frank Samuel
- Franke Barbara
- Franklin Erin
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- Frasier Mark
- Frouin Vincent
- Fröhner Juliane
- Fukunaga Masaki
- Gaikwad Mrunalini
- Galasko Douglas
- Garavan Hugh
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- Gauss Katharina
- Ge Tian
- Geldmacher David
- Gessert Devon
- Ghanbari Mohsen
- Giddaluru Sudheer
- Gigliotti Christina
- Gil Yolanda
- Gillespie Nathan A
- Glahn David C
- Gloer Katherine
- Goldman Aaron L
- Goldstein Bonnie S
- Goldstein David B
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- Gowland Penny
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- Grabe Hans J
- Grabe Hans Jörgen
- Grachev Igor D
- Graff-Radford Neill R
- Grasby Katrina L
- Green Davis Robert C
- Green Melissa J
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- Green Robert C
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- Griffith Randall
- Grimmer Yvonne
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- Grossman Hillel
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- Hake Ann Marie
- Hansell Narelle K
- Hardy Peter
- Hariri Ahmad R
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- Harris Mathew A
- Harrison Marc B
- Hart David
- Hartman Catharina A
- Harvey Danielle
- Hashimoto Ryota
- Haswell Courtney C
- Hauser Michael
- Hauser Robert
- Hawkins Keith A
- Hefti Franz
- Heidebrink Judith L
- Heindel Walter
- Heinz Andreas
- Heinz Andreas
- Heinzen Erin L
- Henskens Frans A
- Hergesheimer Lindsey
- Herms Stefan
- Hernando Raymundo
- Herring Scott
- Heslenfeld Dirk J
- Hetelle Joel
- Hewitt David L
- Heyn Chris Chinthaka
- Hibar Derrek P
- Hillegers Manon H J
- Himali Jayandra J
- Ho Beng-Choon
- Ho New Fei
- Hoehn David
- Hoekstra Pieter J
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- Hofer Edith
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- Hoffmann Wolfgang U
- Hofman Albert
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- Holsboer Florian
- Holtzman David
- Homuth Georg
- Hong L Elliot
- Honig Lawrence S
- Hoogman Martine
- Hopkins William D
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- Hosten Norbert
- Hottenga Jouke-Jan
- Hsiao John
- Hsiung Ging-Yuek Robin
- Hu Shu-Ching
- Hulshoff Pol Hilleke E
- Hunter Christine
- Hynes Mary L
- Häusler Alexander N
- Håberg Asta K
- Ihlenfeld Albrecht
- Ikeda Masashi
- Ikram M Arfan
- Ikram M Arfan
- Ing Alex
- Initiative Alzheimer’s Disease Neuroimaging
- Initiative Parkinson’s Progression Markers
- Iranzo Alex
- Isaacson Stuart
- Isensee Corinna
- Ismail M Saleem
- Ittermann Bernd
- Jack Clifford R
- Jack Clifford R
- Jagust William
- Jahanshad Neda
- James Angela
- James Olga
- James Raymond
- Jang MiHyun
- Jankovic Joseph
- Janowitz Deborah
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- Jansen Iris E
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- Jernigan Terry L
- Jia Tianye
- Jia Tianye
- Jian Xueqiu
- Jiang Jiyang
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- Jimenez Gustavo
- Jockwitz Christiane
- Johnson Kathleen
- Johnson Keith A
- Johnson Kris
- Johnson Nancy
- Johnson Patricia Lynn
- Johnson Sterling
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- Karama Sherif
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- Kuller Lew
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- Lin Honghuang
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- Logue Mark
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- Longstreth William T
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- Martinot Jean-Luc
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- Mason Sara S
- Mathalon Daniel H
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- Matthews Brandy R
- Matthews Sarah
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- Mazoyer Bernard
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- Melzer Tracy R
- Mendick Susan
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- Mesulam Marek-Marsel
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- Meyer-Lindenberg Andreas
- Michie Patricia T
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- Miller Delwyn D
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- Smith Karen Ekstam
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- Thalamuthu Anbupalam
- Thomas Cathi-Ann
- Thomopoulos Sophia I
- Thompson Paul
- Thompson Paul M
- Tingus Kathleen
- Tinklenberg Jared
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- Toga Arthur W
- Toga Arthur W
- Tolosa Eduardo
- Tooney Paul A
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- Tran Baochan
- Tremont Geoffrey
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- Trollor Julian
- Trollor Julian N
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- Turner Raymond Scott
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- Umek Robert
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- van der Brug Marcel
- van der Lee Sven J
- van der Meer Dennis
- Van der Wee Nic J A
- van Donkelaar Marjolein M J
- van Duijn Cornelia M
- van Dyck Christopher H
- van Eijk Liza
- van Erp Theo G M
- van Haren Neeltje E M
- van Noort Betteke
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- Völzke Henry
- Walter Henrik
- Walter Henrik
- Walter Sarah
- Walton Esther
- Wang Mingyuan
- Wang Yunpeng
- Ward Chad
- Wardlaw Joanna M
- Wardlaw Joanna M
- Weber Bernd
- Weinberger Daniel R
- Weiner Michael
- Weiner Michael W
- Weintraub Sandra
- Wen Wei
- Wen Wei
- Westlye Lars T
- Whelan Christopher D
- Whelan Robert
- Whelan Robert
- White Tonya
- Willeke Diana
- Williams Karen
- Williams Steve
- Wilson Renee
- Winkfield David
- Witbracht Megan
- Witt Stephanie H
- Witte A Veronica
- Wittfeld Katharina
- Wittfeld Katharina
- Wolf Christiane
- Wolfers Thomas
- Wolk David A
- Womack Kyle
- Wong Terence Z
- Woo Ellen
- Wright Margaret J
- Wright Margaret J
- Wu Chuang-Kuo
- Wu Jing Qin
- Wurster Isabel
- Xia Rui
- Yamamori Hidenaga
- Yanez Beatriz
- Yang Mia
- Yang Qiong
- Yang Qiong
- Yankey Jon
- Yasuda Clarissa L
- Yeh Randy
- Yesavage Jerome
- Zamrini Edward
- Zare Habil
- Zaremba Dario
- Zhang Zuo
- Zhou Juan
- Zhu Alyssa H
- Zimmerman Earl A
- Ziolkowski Jaimie
- Zsembik Leo C P
- Zwiers Marcel P
- Publication venue
- 'American Association for the Advancement of Science (AAAS)'
- Publication date
- 01/01/2020
- Field of study
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
The National Early Warning Score and its subcomponents recorded within ±24 hours of emergency medical admission are poor predictors of hospital-acquired acute kidney injury
- Author
- Alexander Jake
- Allendorf Fred
- Antunes Pedro M.
- Aronson James
- Bacher Sven
- Bardgett Richard
- Bertolino Sandro
- Bishop Melanie
- Blackburn Tim M.
- Blakeslee April
- Blumenthal Dana
- Bortolus Alejandro
- Buckley Ralf
- Buckley Yvonne
- Byers Jeb
- Callaway Ragan M.
- Campbell Faith
- Campbell Karl
- Campbell Marnie
- Carlton James T.
- Cassey Phillip
- Catford Jane
- Celesti-Grapow Laura
- Chang Andrew
- Chapman John
- Chytry Milan
- Clark Paul
- Clewell Andre
- Clode Joao Canning
- Clout Mick
- Cohen Andrew
- Cowan Phil
- Cowie Robert H.
- Crall Alycia W.
- Crooks Jeff
- Deveney Marty
- Dixon Kingsley
- Dobbs Fred C.
- Duffy David Cameron
- Duncan Richard
- Ehrlich Paul R.
- Eldredge Lucius
- Evenhuis Neal
- Fausch Kurt D.
- Feldhaar Heike
- Firn Jennifer
- Fowler Amy
- Galil Bella
- Garcia-Berthou Emili
- Geller Jonathan
- Genovesi Piero
- Gerber Esther
- Gherardi Francesca
- Gollasch Stephan
- Gordon Doria
- Graham Jim
- Gribben Paul
- Griffen Blaine
- Grosholz Edwin D.
- Heinz Mueller-Schaerer
- Hewitt Chad
- Hierro Jose L.
- Hulme Philip
- Hutchings Pat
- Jarosik Vojtech
- Jeschke Jonathan M.
- Johnson Chris
- Johnson Ladd
- Johnston Emma L.
- Jones Carl G.
- Keller Reuben
- King Carolyn M.
- Knols Bart G. J.
- Kollmann Johannes
- Kompas Thomas
- Kotanen Peter M.
- Kowarik Ingo
- Kuehn Ingolf
- Kumschick Sabrina
- Leung Brian
- Liebhold Andrew
- MacIsaac Hugh
- Mack Richard
- McCullough Deborah G.
- McDonald Robbie
- Merritt David M.
- Meyerson Laura
- Minchin Dan
- Mooney Harold A.
- Morisette Jeffrey T.
- Moyle Peter
- Murray Brad R.
- Nehring Stefan
- Nelson Wendy
- Nentwig Wolfgang
- Novak Stephen J.
- Occhipinti Anna
- Ojaveer Henn
- Osborne Bruce
- Ostfeld Richard S.
- Parker John
- Pederson Judith
- Pergl Jan
- Phillips Megan L.
- Pysek Petr
- Rejmanek Marcel
- Ricciardi Anthony
- Richardson David
- Ricotta Carlo
- Rilov Gil
- Ritchie Euan
- Robertson Peter A.
- Roman Joe
- Ruiz Gregory
- Schaefer Hanno
- Schaffelke Britta
- Schierenbeck Kristina A.
- Schmitz Don C.
- Schwindt Evangelina
- Seeb Jim
- Simberloff Daniel
- Smith Gideon F.
- Smith L. David
- Stohlgren Thomas
- Strayer David L.
- Strong Donald
- Sutherland William J.
- Therriault Thomas
- Thuiller Wilfried
- Torchin Mark
- van der Putten Wim H.
- Vila Montserrat
- Von Holle Betsy
- Wallentinus Inger
- Wardle David
- Williamson Mark
- Wilson John
- Winter Marten
- Wolfe Lorne M.
- Wonham Marjorie
- Wright Jeff
- Zabin Chela
- Publication venue
- 'Royal College of Physicians'
- Publication date
- 07/07/2011
- Field of study
YesBackground: Hospital-acquired Acute Kidney Injury (H-AKI) is a common cause of avoidable morbidity and mortality.
Aim: To determine if the patients’ vital signs data as defined by a National Early Warning Score (NEWS), can predict H-AKI following emergency admission to hospital.
Methods: Analyses of emergency admissions to York hospital over 24-months with NEWS data. We report the area under the curve (AUC) for logistic regression models that used the index NEWS (model A0), plus age and sex (A1), plus subcomponents of NEWS (A2) and two-way interactions (A3). Likewise for maximum NEWS (models B0,B1,B2,B3).
Results: 4.05% (1361/33608) of emergency admissions had H-AKI. Models using the index NEWS had the lower AUCs (0.59 to 0.68) than models using the maximum NEWS AUCs (0.75 to 0.77). The maximum NEWS model (B3) was more sensitivity than the index NEWS model (A0) (67.60% vs 19.84%) but identified twice as many cases as being at risk of H-AKI (9581 vs 4099) at a NEWS of 5.
Conclusions: The index NEWS is a poor predictor of H-AKI. The maximum NEWS is a better predictor but seems unfeasible because it is only knowable in retrospect and is associated with a substantial increase in workload albeit with improved sensitivity.The Health Foundatio
“Anti-Judäismus” in der Hebräischen Bibel der Fall: Ezechiel
- Author
- Publication venue
- 'Brill'
- Publication date
- 01/01/1996
- Field of study
Non-natives: 141 scientists object [Letter]
- Author
- Allendorf Fred
- Antunes Pedro
- Aronson James
- Bacher Sven
- Bardgett Richard
- Bertolino Sandro
- Bishop Melanie
- Blackburn Tim M.
- Blakeslee April
- Blumenthal Dana
- Bortolus Alejandro
- Buckley Ralf
- Buckley Yvonne
- Byers Jeb
- Callaway Ragan
- Campbell Faith
- Campbell Karl
- Campbell Marnie
- Carlton James T.
- Cassey Phillip
- Catford Jane
- Celesti-Grapow Laura
- Chang Andrew
- Chapman John
- Chytry Milan
- Clarke Paul A.
- Clewell Andre
- Clout Mick
- Code Canning Joao
- Cohen Andrew
- Cowan Phil
- Cowie Robert
- Crall Alycia
- Crooks Jeff
- Deveney Marty
- Dixon Kingsley
- Dobbs Fred
- Duffy David Cameron
- Duncan Richard
- Ehrlich Paul R.
- Eldredge Lucius
- Evenhuis Neal
- Fausch Kurt
- Feldhaar Heike
- Firn Jennifer
- Fowler Amy
- Galil Bella
- Garcia-Berthou Emili
- Geller Jonathan
- Genovesi Piero
- Gerber Esther
- Gherardi Francesca
- Gollasch Stephan
- Gordon Doria
- Graham Jim
- Gribben Paul
- Griffen Blaine
- Grosholz Edwin
- Hewitt Chad
- Hierro Jose L.
- Hulme Philip
- Hutchings Pat
- Jake Alexander
- Jarosik Vojtech
- Jeschke Jonathan
- Johnson Chris
- Johnson Ladd
- Johnston Emma L.
- Jones Carl G.
- Keller Reuben
- King Carolyn
- Knols Bart G.J.
- Kollmann Johannes
- Kompas Thomas
- Kotanen Peter M.
- Kowarik Ingo
- Kuhn Ingolf
- Kumschick Sabrina
- Leung Brian
- Liebhold Andrew
- MacIsaac Hugh
- Mack Richard
- McCullough Deborah G.
- McDonald Robbie
- Merritt David
- Meyerson Laura
- Minchin Dan
- Mooney Harold
- Morisette Jeffrey
- Moyle Peter
- Muller-Scharer Heinz
- Murray Brad R.
- Nehring Stefan
- Nelson Wendy
- Nentwig Wolfgang
- Novak Stephen
- Occhipinti Anna
- Ojaveer Henn
- Osborne Bruce
- Ostfeld Richard
- Parker John
- Pederson Judith
- Pergl Jan
- Phillips Megan
- Pysek Petr
- Rejmanek Marcel
- Ricciardi Anthony
- Richardson David
- Ricotta Carlo
- Rilov Gil
- Ritchie Euan
- Robertson Peter A.
- Roman Joe
- Ruiz Gregory
- Schaefer Hanno
- Schaffelke Britta
- Schierenbeck Kristina
- Schmitz Don C.
- Schwindt Evangelina
- Seeb Jim
- Simberloff Daniel
- Smith Gideon F.
- Smith L. David
- Stohlgren Thomas
- Strayer David L.
- Strong Donald
- Sutherland William J.
- Therriault Thomas
- Thuiller Wilfried
- Torchin Mark
- van der Putten Wim
- Vila Montserrat
- Von Holle Betsy
- Wallentinus Inger
- Wardle David
- Williamson Mark
- Wilson John
- Winter Marten
- Wolfe Lorne
- Wonham Marjorie
- Wright Jeff
- Zabin Chela
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2011
- Field of study
Peer reviewe
What's in a Name? The Letterhead Impact Project
- Author
- Abrams Robert H.
- Angel Marina
- Ariens Michael
- Balkin J. M.
- Balkin J. M.
- Berger Mitchell
- Ceci Stephen J.
- Closen Michael L.
- Collier Charles W.
- Crane Diana
- Dubin Jon C.
- Dussias Allison M.
- Ehrlich Scott B.
- Ellman Ira Mark
- Fairweather James S.
- Ferber Marianne A.
- Fidler Josh E.
- Fuchsberg Jacob D.
- Gardner James A.
- Garfield Alan E.
- Garon Jon M.
- Geier Deborah A.
- George Tracey E.
- Gerrity Dennis M.
- Geyh Charles Gardner
- Geyh Charles Gardner
- Goldstein Anne B.
- Goodrich Doris West
- Gordon Wendy J.
- Hamermesh Lawrence A.
- Hayman Robert L.
- Hibbitts Bernard J.
- Houh Emily M. S.
- Howe Scott
- Jarvis Robert M.
- Klein Christine A.
- Korobkin Donald R.
- Krotoszynski Ronald J.
- Laband David N.
- Landsman Stephan
- Leibman Jordan H.
- Lindgren James
- Lindgren James
- Martinez Leo P.
- McGreal Paul E.
- McGreal Paul E.
- McGreal Paul E.
- McGreal Paul E.
- McGreal Paul E.
- McGreal Paul E.
- McGreal Paul E.
- McGreal Paul E.
- Merton Robert K.
- Mulhern J.Peter
- Oppenheimer David Benjamin
- Page William H.
- Page William H.
- Patterson Dennis M.
- Peters Douglas P.
- Pielemeier James R.
- Piette Michael J.
- Posner Richard A.
- Rains Robert E.
- Rotunda Ronald D.
- Saunders Nathan H.
- Shapiro Fred R.
- Shapiro Fred R.
- Smith Bradley A.
- Stern Barry Jeffrey
- Subotnik Dan
- Swygert Michael I.
- Thomas David A.
- Thorndike Edward L.
- Tobias Carl
- Whitford William C.
- Zuckerman Harriet
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Adair L. S.
- Adan R.
- Adan Roger A. H.
- Alavere H.
- Albrecht E.
- Alexander Graeme
- Alfredsson Lars
- Amin N.
- Anderson Carl A
- Ando Tetsuya
- Andreassen Ole A
- Ang W.
- Antel J.
- Aschauer Harald
- Aspelund T.
- Atalay M.
- Baker Jessica H
- Bandinelli S.
- Barrett Jeff C
- Barrett Jeffrey C
- Barroso I.
- Bencko Vladimir
- Benke K.
- Berenson G. S.
- Bergen A. W.
- Bergen A. W.
- Bergen N.
- Bergmann S.
- Berrettini W.
- Berrettini Wade
- Berrettini Wade H.
- Berry D. J.
- Bierut L. J.
- Blackburn H.
- Blackburn Hannah
- Boerwinkle E.
- Boni Claudette
- Boomsma D. I.
- Boraska Perica V.
- Boyd H. A.
- Bradfield J. P.
- Brandt Harry
- Brandys M.
- Brandys Marek K
- Breen Gerome
- Bruson Alice
- Bulik C. M.
- Bulik C. M.
- Bulik Cynthia M
- Bulik Cynthia M
- Burghardt Roland
- Buring J. E.
- Busonero F.
- Byrne E. M.
- Bã¼hren Katharina
- Campbell H.
- Carlberg Laura
- Chanock S. J.
- Charoen P.
- Chasman D. I.
- Chen W.
- Chen Wei Min
- Christian Dina
- Cichon Sven
- Clementi Maurizio
- Cohen Woods Sarah
- Coin L.
- Collier D.
- Collier David A
- Collier David A
- Cone Roger D
- Conlon Peter J
- Cooper C.
- Cornelis M. C.
- Corre T.
- Couper D.
- Cousminer D. L.
- Cousminer D. L.
- Coviello A. D.
- Crawford Steve
- Crisponi L.
- Crow Scott
- D'Adamo P.
- Dackor Jennifer
- Danner Unna N
- Das S.
- Davey Smith G.
- Davis O. S.
- Davis Oliver S. P.
- de Faire U.
- de Geus E. J.
- de Kove Carolien
- De Zwaan M.
- de Zwaan Martina
- Dedoussis G. V.
- Dedoussis George
- Degortes Daniela
- Deloukas P.
- Demerath E. W.
- Desocio Janiece E
- Dick Danielle M
- Dikeos Dimitris
- Ding Bo
- Dmitrzak Weglarz Monika
- Docampo Elisa
- Dominiczak Anna
- Duncanson Audrey
- Dã¶ring A.
- Easton D. F.
- Econs M. J.
- Edkins Sarah
- Egberts K. M.
- Egberts Karin
- Ehrlich S.
- Ehrlich Stefan
- Eiriksdottir G.
- Elks C. E.
- Elliott P.
- Emilsson V.
- Eriksson J.
- Esko T.
- Esko Tãµnu
- Espeseth Thomas
- Estivill X.
- Estivill Xavier
- Evans D. M.
- Farmer Anne
- Favaro Angela
- Feenstra B.
- Feenstra B.
- Fernández Aranda Fernando
- Ferreli L.
- Ferrucci L.
- Fichter M. M.
- Finan Chris
- Fischer Krista
- Flexeder C.
- Floyd James A. B.
- Floyd James A. B.
- Folsom A. R.
- Foretova Lenka
- Foroud T.
- Forzan Monica
- Franceschini N.
- Franklin C. S.
- Franklin Christopher S
- Franklin Christopher S
- Frayling T.
- Freathy R. M.
- Fã¶cker M.
- Gaborieau Valerie
- Gaillard R.
- Gallinger Steven
- Gambaro Giovanni
- Garcia M.
- Gasparini P.
- Geller F.
- Geller F.
- Gieger C.
- Giegling Ina
- Gillman M.
- Gillman Mathew
- Goh L. K.
- Gonidakis Fragiskos
- Gorwood Philip
- Grant S. F.
- Grant S. F. A.
- Gratacos Monica
- Gray Emma
- Groen Blokhuis M.
- Gudbjartsson D. F.
- Gudnason V.
- Guo Y.
- Guo Yiran
- Guxens M.
- Hadley D.
- Hakonarson H.
- Hakonarson H.
- Hakonarson Hakon
- Hall P.
- Halmi K. A.
- Hankinson S. E.
- Harris T. B.
- Hattersley A. T.
- Hauser Joanna
- Haworth C. M.
- Hayward C.
- He C.
- Heath A. C.
- Hebebrand J.
- Hebebrand J.
- Hebebrand Johannes
- Heid I. M.
- Heinrich J.
- Helder Sietske
- Hendriks Judith
- Herms Stefan
- Hernandez D. G.
- Herpertz Dahlmann B.
- Herpertz Dahlmann Beate
- Herzog W.
- Herzog Wolfgang
- Hill Adrian
- Hilliard Christopher E
- Hinney A
- Hinney A.
- Hinney Anke
- Hirschhorn J. N.
- Hocher B.
- Hofman A.
- Holloway J. W.
- Holst C.
- Horikoshi M.
- Hottenga J. J.
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- Huckins Laura M
- Hudson James I
- Huemer Julia
- Huikari V.
- Hunt Sarah E
- Hunter D. J.
- Hypponen E.
- Iezebrink Kirsty
- Illig T.
- Imgart Hartmut
- Ingelsson E.
- Inoko Hidetoshi
- Iã±iguez C.
- Jaddoe V. W.
- Jall S.
- Janout Vladimir
- Jarvelin M. R.
- Jiménez Murcia Geòrgia Escaramà Susana
- Johnson A. D.
- Johnson Craig
- Julia Antonio
- Jã¤rvelin M. R.
- Kaakinen M.
- Kalsi Gursharan
- Kaplan A. S.
- Kaplan Allan S
- Kaprio Jaakko
- Karasik D.
- Karhunen Leila
- Karwautz Andreas
- Kas Martien J. H
- Kaye W.
- Kaye Walter
- Keel Pamela
- Kennedy James L
- Keski Rahkonen Anna
- Kesselmeier M.
- Khaw K. T.
- Kiel D. P.
- Kilpelã¤inen T. O.
- Kilpelã¤inen T. O.
- Kirin M.
- Klareskog Lars
- Klump K. L.
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- Knudsen Gun Peggy S.
- Koeleman Bobby P. C.
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- Koller D. L.
- Komaki Gen
- Koubek Doris
- Kowgier M.
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- Lehtimã¤ki T.
- Levitan Robert D
- Levy D.
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- Li Dong
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- Lichtenstein Paul
- Lilenfeld Lisa
- Lin P.
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- Lindi V.
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- Martaskova Debora
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- Mattingsdal Morten
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- Mcardle P. F.
- Mcardle W. L.
- Mcardle Wendy L
- Mccarthy M. I.
- Mcginnis Ralph
- Mcguffin Peter
- Melbye M.
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- Merl Elisabeth
- Metspalu A.
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- Meulenbelt Ingrid
- Middeldorp C.
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- Morgan Linda
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- Murray A.
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- Murray J. C.
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- Mã¤nnik Katrin
- Mã¼ller T. D.
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- Navratilova Marie
- Nelis M.
- Nengut Suna Gumuscu
- Ness A. R.
- Nivard M.
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- Northstone K.
- Ntalla I.
- Ntalla Ioanna
- O'Reilly P. F.
- Oken E.
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- Ong K. K.
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- Ophoff Roel A
- Ouwehand Willem H
- Oâ\u80\u99toole Julie K
- Padyukov Leonid
- Palmer L. J.
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- Palotie A.
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- Pantel Jacques
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- Pennell C. E.
- Pennell C. E.
- Perica Vesna Boraska
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- Plump A. S.
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- Porcu E.
- Potter Simon
- Pourcain B. S.
- Pouta A.
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- Price T. S.
- Prokopenko I.
- Rabionet Raquel
- Raevuori Helkamaa Anu
- Rafnar T.
- Raitakari O. T.
- Rajewski Andrzej
- Ramoz Nicolas
- Rayner N. William
- Reichborn Kjennerud Ted
- Reinvang Ivar
- Rice J. P.
- Rich Stephen S
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- Ripatti Samuli
- Ritchie Graham R. S.
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- Rudan I.
- Rujescu Dan
- Rybakowski Filip
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- Scherag A.
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- Scherag Susann
- Scherer Stephen W
- Schlessinger D.
- Schmidt Ulrike
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- Schreiber Stefan
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- Segr㨠A. V.
- Sheerin Neil
- Shuldiner A. R.
- Siitonen N.
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- Simpkin Douglas
- Slachtova Lenka
- Sladek Rob
- Slagboom P. Eline
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- Slopien Agnieszka
- Smith A. V.
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- Southam Lorraine
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- Strengman Eric
- Strober Michael
- Sulem P.
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- Sunyer J.
- Szatkiewicz Jin P
- Szeszenia Dabrowska Neonila
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- Taico Chrysecolla
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- Teo Y. Y.
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- Toniolo D.
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- Tozzi Federica
- Trace Sara E
- Treasure Janet
- Treasure Janet
- Tryggvadottir L.
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- Tsitsika Artemis
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- Tyrer J.
- Tziouvas Konstantinos
- Uda M.
- Uitterlinden A. G.
- Uitterlinden A. G.
- Ulivi S.
- Valcã¡rcel B.
- van Beijsterveldt T.
- van Dam R. M.
- van Duijn C. M.
- Van Elburg A.
- van Elburg Annemarie A
- Van Furth Eric F.
- van Meurs J. B.
- van Wingerden S. H.
- Vannberg Frederik O
- Versini Audrey
- Visser J. A.
- Volckmar A. L.
- Vollenweider P.
- Waeber G.
- Wagner Gudrun
- Wareham N. J.
- Warrington M.
- Warrington N. M.
- Waterworth D. M.
- Weedon M. N.
- White S.
- Whittaker Pamela
- Wichmann H. E.
- Wichmann H. Erich
- Widen E.
- Widã©n E.
- Widã©n Elisabeth
- Willemsen G.
- Willemsen G.
- Wilson J. F.
- Wilson J. F.
- Winkler T. W.
- Woodside D. Blake
- Wright A. F.
- Yaghootkar H.
- Yilmaz Zeynep
- Young L.
- Zeggini E.
- Zeggini E.
- Zeggini Eleftheria
- Zeggini Eleftheria
- Zerwas Stephanie
- Zgaga L.
- Zhai G.
- Zhao J. H.
- Zhuang W. V.
- Zipfel S.
- Zipfel Stephan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10-5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10-06/Pfemales: 3.45 × 10-07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
- Author
- Abecasis G. R.
- Absher D.
- Adair L. S.
- Adan R.
- Adan Roger A. H.
- Alavere H.
- Albrecht E.
- Albrecht E.
- Alexander Graeme
- Alfredsson Lars
- Alizadeh B.
- Amin N.
- Amin N.
- Amouyel P.
- Anderson Carl A.
- Ando Tetsuya
- Andreassen Ole A.
- Ang W.
- Antel J.
- Aschauer Harald
- Aspelund T.
- Asselbergs F. W.
- Assimes T. L.
- Atalay M.
- Atalay M.
- Attwood A. P.
- Baker Jessica H.
- Balmforth A. J.
- Bandinelli S.
- Barrett Jeff C.
- Barrett Jeffrey C.
- Barroso I.
- Barroso I.
- Basart H.
- Beilby J.
- Bencko Vladimir
- Benke K.
- Berenson G. S.
- Berg J.
- Bergen A. W.
- Bergen Andrew W.
- Bergen N.
- Bergmann S.
- Berndt S. I.
- Berrettini W.
- Berrettini Wade
- Berrettini Wade H.
- Berry D. J.
- Bierut L. J.
- Blackburn H.
- Blackburn Hannah
- Blackwood D.
- Boehm B. O.
- Boehnke M.
- Boerwinkle E.
- Boerwinkle E.
- Boezen H. M.
- Boni Claudette
- Bonnycastle L. L.
- Boomsma D. I.
- Boomsma D. I.
- Boraska Perica V.
- Borecki I. B.
- Boyd H. A.
- Bradfield J. P.
- Bragg-Gresham J. L.
- Brambilla P.
- Brandt Harry
- Brandys M.
- Brandys Marek K.
- Breen Gerome
- Bruinenberg M.
- Bruinenberg M.
- Bruson Alice
- Bulik C. M.
- Bulik Cynthia M.
- Bulik Cynthia M.
- Bulik Cynthia M.
- Burghardt Roland
- Buring J. E.
- Busonero F.
- Byrne E. M.
- Bühren Katharina
- Bültmann U.
- Cadby G.
- Campbell H.
- Campbell H.
- Campbell H.
- Carlberg Laura
- Caulfield M. J.
- Cavanagh J.
- Chanock S. J.
- Chanock S. J.
- Charoen P.
- Chasman D. I.
- Chasman D. I.
- Chen W.
- Chen Wei-Min
- Children's Hospital of Philadelphia/Price Foundation
- Chines P. S.
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- WTCCC3
- Yaghootkar H.
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- Zeggini E.
- Zeggini E.
- Zeggini Eleftheria
- Zeggini Eleftheria
- Zerwas Stephanie
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 17/05/2016
- Field of study
The maintenance of normal body weight is disrupted in patients with anorexia nervosa (AN) for prolonged periods of time. Prior to the onset of AN, premorbid body mass index (BMI) spans the entire range from underweight to obese. After recovery, patients have reduced rates of overweight and obesity. As such, loci involved in body weight regulation may also be relevant for AN and vice versa. Our primary analysis comprised a cross-trait analysis of the 1000 single-nucleotide polymorphisms (SNPs) with the lowest P-values in a genome-wide association meta-analysis (GWAMA) of AN (GCAN) for evidence of association in the largest published GWAMA for BMI (GIANT). Subsequently we performed sex-stratified analyses for these 1000 SNPs. Functional ex vivo studies on four genes ensued. Lastly, a look-up of GWAMA-derived BMI-related loci was performed in the AN GWAMA. We detected significant associations (P-values <5 × 10−5, Bonferroni-corrected P<0.05) for nine SNP alleles at three independent loci. Interestingly, all AN susceptibility alleles were consistently associated with increased BMI. None of the genes (chr. 10: CTBP2, chr. 19: CCNE1, chr. 2: CARF and NBEAL1; the latter is a region with high linkage disequilibrium) nearest to these SNPs has previously been associated with AN or obesity. Sex-stratified analyses revealed that the strongest BMI signal originated predominantly from females (chr. 10 rs1561589; Poverall: 2.47 × 10−06/Pfemales: 3.45 × 10−07/Pmales: 0.043). Functional ex vivo studies in mice revealed reduced hypothalamic expression of Ctbp2 and Nbeal1 after fasting. Hypothalamic expression of Ctbp2 was increased in diet-induced obese (DIO) mice as compared with age-matched lean controls. We observed no evidence for associations for the look-up of BMI-related loci in the AN GWAMA. A cross-trait analysis of AN and BMI loci revealed variants at three chromosomal loci with potential joint impact. The chromosome 10 locus is particularly promising given that the association with obesity was primarily driven by females. In addition, the detected altered hypothalamic expression patterns of Ctbp2 and Nbeal1 as a result of fasting and DIO implicate these genes in weight regulation
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
- Abdelkareem Mohamed
- Abdelkarem Mohamed
- Abdelkarim Mostafa
- Abdelkhalek Mohamed
- Abdellah Fatima
- Abdelmajeed Ahmed
- Abdelmalik Abubaker
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- Alqudah Majdi Ali
- Alqudah Sadeel
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- Alsulaimani Thuwaiba
- Alsuliman Yazeed
- Alsultan Afnan
- Alsunna Zaid
- Alsuwaimel Munir
- Alsuwaydani Saleh
- Alsuwiyah Suhir
- Altaf Abdulmalik
- Altaf Humera Naz
- Altaf Kiran
- Altaf Zahra
- Altahan Talal
- Altaher Assma
- Altalhi Bassam
- Altamirano-Villarroel Jaime
- Altana Cristian
- Althobaiti Awwadh
- Althobaiti Waleed
- Althubaiti Ibrahim
- Althumairi Azah
- Altieri Gaia
- Altinel Yuksel
- Altintoprak Fatih
- Altobal Ahmed
- Altoijry Abdulmajeed
- Altom Roula
- Altoumi Manal Ahmed
- Alturki Abdulrahman
- Altuwaijri Mohammad
- Altuwaijri Talal
- Altuwayjiri Basmah
- Altwejri Ikhlass
- Alvarado Antonio
- Alvarado Rosalinda
- Alvarenga Vítor
- Alvarez Andres
- Alvarez Estibaliz
- Alvarez Fernando Andres
- Alvarez Maria Regina
- Alvarez-Gallego Mario
- Alves Fernanda
- Alves Paulo
- Ameer Ahmed Al
- Amine Chamakhi Ahmed
- Amri Abdulrahman Al
- Amri Ayman Al
- Andolfi Enrico
- Andrade Arnulfo
- Andrade Marlene
- Andraschofsky Tibor Oliver
- Andreani Lorenzo
- Andreani Stefano
- Andreatta Erika
- Andrejevic Predrag
- Andreotti Isis
- Andrews Emmet
- Andrews Kiah
- Andriamanana Liantsoa
- Andrianakis Alexandros
- Andriantsoa Herimampionona E
- Andro Christophe
- Androus Farah
- André Benoît
- Aneke Ikenna Anderson
- Anesi Alexandre
- Anesti Katerina
- Ang Angeli Anne
- Ang Keng-Leong
- Ang Wei-Wen
- Angel Carol
- Angel Gustavo Adolfo
- Angeles Martina Aida
- Angelico Roberta
- Angelides Sophia
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angenete Eva
- Angerer Rafael
- Angermann Reinhard
- Aniakwo Luke Adagrah
- Anicetti Joshua
- Aning Daniel Gyawu
- Anipole Olalekan
- Anitha Dusabimana
- Aniukstyte Laura
- Anjarwalla Naffis
- Anjum Momina
- Anjum Waleed
- Ankadavar Sushil
- Ankeny Jacob
- Ankobea-Kokroe Frank
- Annan Nathaniel
- Annicchiarico Alfredo
- Annicchiarico Paolo
- Anning Rebecca
- Annino Filippo
- Anoso Willmar
- Anract Philippe
- Arar Ahmad Abo
- Artal Raquel Angulo
- Asadi Tala Al
- Athath Samer Al
- Azab Mohammed
- Azhar Rawan Al
- Azize Diallo Abdoul
- Azzeh Nimer Al
- Badaai Ghalib Al
- Bakr Amna Abou
- Balushi Nawf Al
- Balushi Zainab Al
- Barnes Nicholas Adamson
- Bartolomé Santiago Alonso
- Bassam Wameedh Al
- Bdour Zakaria Al
- Benhamou Rita Ait
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- Bofill Marta Alomar
- Boira Mar Achalandabaso
- Bonito Alba Correa
- Carrillo Carolina Alfonso
- Claudiu Rad Costel
- Corella Fernando
- Coretti Guido
- Corkill Joel
- Cornali Tommaso
- Cornford Philip
- Corona-Cruz Jose
- Corpodean Alma-Andreea
- Corr Paula
- Correia Ana Margarida
- Correia Bernardo
- Correia Rebeca
- Corrigan Mark
- Corripio-Sanchez Ramon
- Corriveau-Durand Simon
- Corso Julian
- Cortes Henry
- Cortes Ludivina
- Cortes Ruben
- Cortes Susana
- Cortes-Flores Ana Olivia
- Cortes-Torres Edgar-Joaquin
- Cortinovis Sara
- Cortinovis Umberto
- Cortés-Guiral Delia
- Cory Jordan
- Cosimelli Maurizio
- Cossu Maria Laura
- Costa Francesco
- Costa Francisca
- Costa Laura
- Costa Paulo Matos
- Costa Tainá
- Costache Andreea
- Costache Victor
- Costantino Andrea
- Costanzi Andrea
- Costas-Chavarri Ainhoa
- Costas-Ochoa Simbad
- Costea Radu
- Costeira Beatriz
- Costeira Cristina
- Costi Renato
- Cote Mathieu
- Cote Maxime
- Cotoia Antonella
- Cotta Estefanía
- Cottin Tatiana
- Cottu Pietrina
- Coughlin Patrick
- Courval Valérie
- Crespo Francesc Angles
- Côté Mathilde
- Dahabrh Seif Al
- De Medeiros Jorge
- De Michele Federico
- De Nardi Paola
- De Nunzio Cosimo
- De Palma Alessandra
- De Palma Giovanni Domenico
- De Pano Jojiemar
- De Paola Gilda
- De Prizio Marco
- De Riu Giacomo
- De Robles Marie Shella
- De Rosa Raffaele
- De Santi Silvia
- De Silva Chathuranka
- De Silva Kanishka
- De Simone Belinda
- De Simone Veronica
- De Toma Giorgio
- De Vincenti Rosita
- De Virgilio Armando
- De Vita Carla
- De Vries Jean-Paul PM
- De Wachter Stefan
- De Zuanni Marco
- Deacon Christopher
- Deacon Laura
- Dealino Maria Angela
- Dean Benjamin
- Deb Mainak
- DeBiasio Ashe
- Debo-Aina Adeoye Oluwakanyinsola
- Debrah Samuel
- Debri Laila
- Decker Cassie
- Decker Georges
- Dede Kristof
- Dedemadi Georgia
- Dedey Florence
- Dediulia Natalija
- Deeb Haya
- Defert Coralie
- Degefa Eyueal
- Degefe Derje Worku
- Degefu Hailegebriel
- Degener Stephan
- Deguchi Yoshihiko
- Dehart Dustin
- Deiana Enrica
- Deierl Krisztian
- Dejanovic Tatjana
- Dekeryte Inga
- Dekker Nicole
- Del Basso Celeste
- Del Chiaro Marco
- Del Gaudio Massimo
- Del Giudice Roberto
- Del Rio Paolo
- Del Mathilde
- Delaney Christopher
- Deniz Elif Akova
- Dhafif Anwaar Al
- Dhaheri Mahmood Al
- Dhoun Sajedah Al
- Dosouky Mohammed Al
- Draz Najib Abu
- Duhileb Mohammed Al
- El-Ghani Wael
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- Elwahab Ahmed
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- Faifi Jubran Al
- Farsi Maather Al
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- Faya Camara Abraham
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- Forneris Agustin Albani
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- Gohary Rawda Al
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- Gujjuri Rohan
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- Habes Hessa Al
- Hameed Jumana Abdul
- Hameed Najat Abdul
- Haq Zainab Ahmad
- Harthi Abdulaziz Al
- Hasan Ziad Aboharp
- Hilal Mohammed Abu
- Hosni Mohammed Al
- Humaid Lama Al
- Imaz Ainhoa Andres
- Ingabire Jc Allen
- Jamahir Mohammed Al
- Jarad Ziad Al
- Jarmozi Buthina Al
- Jawad Hussain Al
- Jayyab Mustafa Abu
- Juarranz Miguel Alonso
- Junior Joel
- Júnior Samuel Aguiar
- Kalbani Maha Al
- Kalbani Moza Al
- Kamarajah Sivesh
- Kharusi Lamya Al
- Kharusi Safiya Al
- Khassawneh Ahmad Al
- Koculen
- Köylü Zehra Alan
- Lahham Salim Al
- Lara Iván Andújar
- Lara María Adrien
- Li Elizabeth
- Lucas Miriam Abellan
- Maadany Faraj Al
- Mahdawi Leyla Al
- Mahdy Hossam Al
- Makari Reem Al
- Manji Adil Al-Karim
- Maqtari Siham Al
- Mariño Mauricio Agüero
- Martinez Yicel Alvarez
- Maryam A
- Matas Fernando Alcaide
- Mendoza Veronica Alonso
- Mensah Kwasi Agyen
- Mintah Dominic Annor
- Moagal Rehab Al
- Moawad Karim Abdelraouf
- Mohamed Mohamed Ali
- Mohsen Mustafa Abo
- Momani Tareg Al
- Muhfouz Dima Abu
- Muhtadi Fadhl Al
- Mulke Rahaf Al
- Murgueitio Natalia Cortes
- Mutani Mohammed Al
- Nafesa Aminah Al
- Nahian Syed Al
- Najjar Majed Al
- Najjar Tasneem Al
- Nami Awaji Al
- Nassar Saleh Al
- Nepogodiev Dmitri
- Neto Alfeu Accorsi
- Noval Patricia Corriols
- Nwijy Khaled Ai
- Obead Hamza Abu
- Oliver Renato Aguera
- Omair Shehanah Al
- Otaibi Faisal Al
- Picciochi Maria
- Pinto João Almeida
- Polo Miriam Abdulkarim
- Qadhi Hani Al
- Qudhaya Rashed Al
- Qureshi Talha Ahmed
- Rahim Norazila
- Rahman Noorneza Abdul
- Rahman Norhafiza
- Raisi Amani Al
- Rashed Asmaa Al
- Rego Juliana Almeida
- Riaz Shujat Ahmed
- Riobello Eva Andreu
- Riyami Nihal Al
- Riyami Salim Al
- Ros Conrado Andrés
- Roselló Irene Vives
- Rubio Eva Corral
- Rueda Ignacio Alcalá
- Saad Sarah Ahmed
- Sabti Hilal Al
- Saez Iago Alvarez
- Saied Ghiath Al
- Salam Omar Abdul
- Salama Ibrahim Abdelkader
- Sanany Ghadeer Al
- Santos Daniel Costa
- Sayed Mohamed Al
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- Shaalah Ahmed Abdullah
- Shaibi Maha Al
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- Shanab Ahmed Abo
- Sharie Ahmed Al
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- Subaie Saud Al
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- Tarieh Ammar Abu
- Torres Eva Alvarez
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- Vives Inmaculada
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- Vivian-Taylor Josephine
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- Vlad Ioan Catalin
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- Vladimir Novgorodskii
- Vleminckx Nils
- Vo Uyen Giao
- Vogel Jon
- Vogel Keianna
- Vogel Rachel
- Vogelsang Holger
- Vogler Thomas
- Vogt Kelly
- Vohra Ravinder
- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population
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- Wolfrum Edgar
- Wolfrum Edgar
- Wolfrum Edgar
- Woller Hans
- Woller Henke
- Wrobel Hans
- Yablonka Hanna
- Yablonka Hanna
- Zandman Felix
- Zarusky Jürgen
- Zeidler Manfred
- Ziemann Benjamin
- Zimmerer Hg.
- Zimmermann Volker
- Zürndorf Bearb
- ühen Nachkriegsprozesse
- Publication venue
- 'Vandenhoeck & Ruprecht GmbH & Co, KG'
- Publication date
- Field of study